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Adverse effect of heroin hydrochloride on selected male reproductive parameters in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigated the effects of heroin on selected male reproductive parameters in mice (Balb/C), e.g. body weight, testis weight, gonado-somatic index, sperm viability, concentration of serum testosterone and fertility rate. Seventy-two mice (36 male and 36 female) were used. The male mice were divided into two control and two experimental groups. For evaluation of fertility rate, three mice were chosen from each group. Experimental groups of heroin-dependant mice were divided into two groups: Experimental group I were given heroin at a dose of 5 mg/kg and experimental group II 5 mg/ml, intra-peritone...
Source: Comparative Clinical Pathology - November 18, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Change in haematological profile of pregnant camels (Camelus dromedarius) at termEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Haematological parameters of 28 pregnant camels (Camelus dromedarius) were compared with those of 32 non-pregnant camels (C. dromedarius). The parameters compared were: total erythrocytes count (RBC), haemoglobin (Hb), packed cell volume (PCV), mean corpuscular volume (MCV), mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration and total leucocyte count (TLC). Results obtained indicate that RBC, Hb and PCV decreased in the later stages of pregnancy while TLC remained unchanged. Calculated indices revealed a significant increase in MCV (p < 0.02) of pregnant camels. Conten...
Source: Comparative Clinical Pathology - November 17, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Hemostatic profile, platelets, and blood constituents of the Arabian oryx (Oryx leucoryx)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Hemostatic, hematological, and chemical parameters were determined in 25 captive Arabian oryxes (Oryx leucoryx) of both sexes. Hemostatic parameters included prothrombin time, activated partial thromboplastin time, fibrinogen, and clotting factors activities. Serum concentrations of 26 biochemical and inorganic constituents were determined along with hematological data, namely platelet counts, platelet indices, and red and white blood cell variables. Hemostatic parameters, platelet indices, and many biochemical components are reported for the first time in the Arabian oryx. Relatively low mean platel...
Source: Comparative Clinical Pathology - November 17, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Evaluation of the expression of TLR-2, Dectin-1 and TNF-α level in invasive aspergillosis in cancer miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we explored whether the innate resistance to IA in cancer mice has resulted in altered expression of TLR-2 and Dectin-1 in macrophages (flow cytometry) and production of tumour necrosis factor alpha (TNF-α; ELISA) as well as overall mortality. The data demonstrated significant increases in Dectin-1 and TLR-2 on peritoneal macrophages and mortality in cancer mice intravenously infected with A. fumigatus. TNF-α levels were not significantly increased in this group. Probably, IA causes some disorganization in inflammatory responses. We hypothesize that concomitance of IA and cancer may change the micro-en...
Source: Comparative Clinical Pathology - November 17, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Evaluation of the correlation between tissue reaction and cytokines patterns induced by Alternaria alternate in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract   Alternaria alternata is well-known as a source of allergenic components in the cell wall and cytoplasm of conidia and hyphae that cause respiratory allergic disorders. The purpose of this study was to evaluate tissue reaction and Th2 cytokines in mice exposed to A. alternata. A. alternata was cultured, and fungal extract was prepared by freeze–defreeze and sonication methods. BALB/c mice in one group were sensitized by two intraperitoneal injections of A. alternata extract and then intra-nasally challenged with spores suspended in sterile normal saline solution, and in another group, mice only re...
Source: Comparative Clinical Pathology - November 11, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

New serovars of Leptospira interrogans in cavy (Cavia aperea)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The purpose of this study is to report the occurrence of new serovars of Leptospira interrogans in cavy in Brazil. Blood without anticoagulant was collected from five Cavia aperea to obtain serum for further testing with serum agglutination using eight serovars of L. interrogans. It was observed that four animals had titers for L. butembo, L. bratislava, and L. hardjo. We believe that cavy can be reservoirs and disseminators of these serovars of L. interrogans. Content Type Journal ArticleCategory Brief CommunicationDOI 10.1007/s00580-009-0924-6Authors Lucas Trevisan Gressler, Universidade Federal ...
Source: Comparative Clinical Pathology - November 6, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Different effects of cGMP and cAMP analogs on kinematic parameters of ram epididymal sperm in vitroEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, low concentrations of exogenous cAMP but no cGMP improves the motion parameters of ram epididymal sperm. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00580-009-0922-8Authors Ali Karimi Goodarzi, Islamic Azad University, Karaj Branch Department of physiology, Faculty of Veterinary Medicine Karaj IranHossein Hassanpour, Shahrekord University Department of Physiology, Faculty of Veterinary Medicine Shahrekord IranMasood Teshfam, Islamic Azad University, Science and Research Branch Department of physiology, Faculty of Specialized Veterinary Sciences Tehran Iran Journal Comparati...
Source: Comparative Clinical Pathology - October 28, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Effects of xylazine–ketamine–diazepam anesthesia on blood cell counts and plasma biochemical values in sheep and goatsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  To examine the effects of xylazine, ketamine, diazepam anesthesia on clinical pathology parameters in sheep and goats, seven adult, healthy, non-pregnant Awassi sheep weighing 40–60 kg and seven adult, healthy non-pregnant Damascus breed goats weighing 35 to 55 kg were used. Anesthesia was induced using 0.1 mg/kg xylazine, 5 mg/kg ketamine, and 0.25 mg/kg diazepam as a single intravenous injection. Blood cell counts and plasma biochemical analysis were performed before anesthesia (T0), 2 h after recovery, 24 h after recovery, and 5 days later. Hematological ...
Source: Comparative Clinical Pathology - October 21, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Erratum to: Survey of Clostridium botulinum toxins in Iranian traditional food productsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory ErratumDOI 10.1007/s00580-009-0921-9Authors Hamid Reza Tavakoli, Baqyatallah University of Medical Science Tehran Iran Journal Comparative Clinical PathologyOnline ISSN 1618-565XPrint ISSN 1618-5641 (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - October 21, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Evaluation of milk haptoglobin and amyloid A in high producing dairy cattle with clinical and subclinical mastitis in ShirazEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was designed to evaluate milk haptoglobin (Hp) and milk amyloid A (MAA) as an inflammatory indicator for clinical and subclinical mastitis of cattle in dairy farms in Shiraz, Iran. Forty-three subclinical mastitic cows with a positive California Mastitis Test (CMT) and no clinical signs of mastitis, 28 clinical mastitic cows, and 10 healthy cows with negative CMT were selected. After confirmation of clinical and subclinical mastitis by bacterial identification, milk samples were taken from four quarters of each cow and mixed, and one sample was taken from the pooled milk. The most dominant isolated bacteriu...
Source: Comparative Clinical Pathology - October 16, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Evaluation of relationship between Rotavirus and Coronavirus infections with calf diarrhea by capture ELISAEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract   Rotavirus and Coronavirus are two main causes of severe diarrhea in human infants and many animal species worldwide. Calves up to 3 months old can be affected by these viruses. The importance of these viruses in cattle industry is due to substantial economic loss, treatment costs, and reduced growth rates in beef and dairy calves. Mixed infections caused by Rotavirus and Coronavirus can lead to severe form of diarrhea. In present case-control study, 261 samples of healthy and diarrheic calves from farms around Mashhad were collected. These samples were tested by antigen-capture enzyme-linked i...
Source: Comparative Clinical Pathology - October 15, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Chicken anemia virus infection in broiler chickens in Shahrekord, Iran: serological, hematological, and histopathological findingsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Chicken infectious anemia caused by a single-strand DNA circovirus is a disease in young chickens that is characterized by aplastic anemia, generalized lymphoid atrophy, and immunosuppression. In the present study, the presence of chicken anemia virus (CAV) infection and the hematologic and histopathologic changes in CAV seropositive broiler chickens in Shahrekord region, center of Iran, were investigated. Blood and lymphoid tissue samples were obtained from 271, 2–6-week-old chicks of 23 commercial broiler chicken flocks. Measurement of CAV antibody titers by enzyme-linked immunosorbent assay (EL...
Source: Comparative Clinical Pathology - October 14, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Comparison between microscopic agglutination test (MAT) and enzyme-linked immunosorbent assay (ELISA) for detection of leptospiral antibodies in cattleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was conducted to evaluate two serological techniques, the microscopic agglutination test (MAT) and the enzyme-linked immunosorbent assay (ELISA), for detection of leptospiral antibodies in cattle. Three hundred and fifty five serum samples were collected from five commercial dairy farms in Tehran suburb from December 2004 to June 2005. The results of the MAT protocol showed that 55 serum samples (15.49%) had detectable antibodies against at least one serovar of L. interrogans at a dilution of ≥ 1:100. Icterohaemorrhagiae was the most (42.52%) and ballum the least (1.15%) prevalent serovars among 87 positiv...
Source: Comparative Clinical Pathology - October 13, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

The acute effects of ondansetron on the electrocardiogram in clinically normal dogsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, ondansetron at standard dosages apparently causes ECG changes in healthy dogs. These include marked QT interval prolongation and reduction in heart rate. Although in current experiment, we did not observe serious arrhythmias in this group of dogs, it does not exclude the possibility of ventricular arrhythmias in prolonged use after reaching a certain cumulative dose. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00580-009-0916-6Authors Masoud Selk Ghaffari, Islamic Azad University–Karaj Branch Department of Clinical Sciences, School of Veterinary Medicine Karaj IranAmir Pasha Mo...
Source: Comparative Clinical Pathology - October 7, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Changes of serum amyloid A, haptoglobin, ceruloplasmin, fibrinogen, and lipid-associated sialic acid in sheep fed high grain rations with altered digestive functionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Changes of serum amyloid A (SAA), haptoglobin (Hp), ceruloplasmin, fibrinogen, and lipid-associated sialic acid (LSA) were assessed in sheep fed high grain rations with negative alterations of digestive functions. During a period of 30 days (divided into three equal steps), eight Karakul lambs were divided into a control (n = 4) and an experiment group (n = 4). The control group was fed a ration consisting of 80% alfalfa hay and 20% wheat straw for the whole period of the study. In the experiment group, ground barley was substituted for 40% of the ration for the first step (10 days)...
Source: Comparative Clinical Pathology - October 3, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

A preliminary study of the use of human adipose tissue-derived stem cells for the treatment of streptozotocin-induced diabetes mellitus in a rat modelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The purpose of this study is to determine if intraventricular injection of human adipose tissue-derived stem cells (hADSC) are effective in treating streptozotocin (STZ)-induced diabetes mellitus (DM) in nude rats. Twenty-two adult, male nude rats (strain Crl:NIH-Fox1RNU) were used to induce diabetes using streptozotocin. A single, 150 mg/kg STZ was injected intraperitoneally. Severity of the induced diabetic state was assessed by daily monitoring of body weight, clinical signs, and blood glucose levels. C-peptide was assessed before ADSC injection (T0) and at 3, 5, and 21 days after ADSC ...
Source: Comparative Clinical Pathology - October 1, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Clinical–pathological findings in two cats with slipped capital femoral epiphysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article describes two cases of physeal dysplasia in two cats. Both cats were presented with an acute onset and severe hind limb lameness. Radiographic examination showed a radiolucent line crossing the metaphysis and a capital physeal incongruity with signs of bone resorption at the femoral neck. No other clinical and laboratory anomalies were seen at that time. Excision of the femoral head was performed in both cats. Bone samples were fixed in formalin and processed for a standard histological and histochemical evaluation. The definitive diagnoses were in both cases of physeal dysplasia with slipped capital femo...
Source: Comparative Clinical Pathology - October 1, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Artifactual changes in the haematocrit buffy coat of stored anti-coagulated blood samples of farm animalsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study therefore investigated the artifactual changes that occur in the BCP of stored anti-coagulated blood samples of farm animals. The BCPs of blood samples from a total of 16 cattle, 18 goats, 15 pigs, and 16 chickens were determined immediately upon blood collection to obtain the baseline value (BV). The blood samples were then divided into three parts and stored at 5°C (3–7°C), 30°C (27.5–32.5°C), and 37°C (35.5–38.5°C). Further BCP determinations on the samples were carried out at 24-h intervals for 72 h (3 days). Results showed that there were statistically significant increases (p &...
Source: Comparative Clinical Pathology - September 30, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Alterations of serum tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), and sialic acids in malignant ovine theileriosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The study was designed to evaluate the effect of the severity of Theileria lestoquardi (hirci) infection on tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), and sialic acid concentration in blood sera in a naturally infected sheep. Infected animals (diseased group) comprised 50 Iranian fat-tailed sheep, about 1–2 years old, naturally infected with Theileria lestoquardi (hirci), were divided into three subgroups according to parasitemia rates (<2%, 2–4%, and >4%). As a control group, ten noninfected sheep were also selected. Hematological parameters and levels of TNF-α, IFN-Î...
Source: Comparative Clinical Pathology - September 29, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Mixed mineral deficiencies in a dairy herd with subclinical production disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  An interventional study was performed for a period of 210 days in a dairy farm in Fars province, southern Iran with a history of both poor production and reproduction. Trace mineral deficiencies were suspected as the underlying causes because trace mineral supplements had been dropped from the rations. Serum concentrations of Co, Cu, Fe, Mn, Zn, and also those of Ca, P, Na, Cl, K, and Mg were measured in all lactating and dry cows. The results were compared with the midpoints of the reference values. With the exception of zinc, all studied minerals were significantly low (P < 0.01). The ...
Source: Comparative Clinical Pathology - September 29, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Effects of chytridiomycosis on circulating white blood cell distributions of bullfrog larvae (Rana catesbeiana)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Bullfrogs (Rana catesbeiana) are widely believed to be nonclinical carriers of Batrachochytrium dendrobatidis (Bd), the fungal pathogen that invades keratinized tissues of amphibians and causes the disease, chytridiomycosis. Although most research on this disease focuses on adults, larval anurans are also susceptible to infections in their keratinized mouthparts, and this allows for visual diagnosis of the disease via the degree of mouthpart depigmentation. When an unplanned outbreak of chytridiomycosis occurred in a set of captive bullfrog tadpoles in our lab, we conducted the current investigation ...
Source: Comparative Clinical Pathology - September 29, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Effects of NOC-18 (nitric oxide donor) and TRIM (nitric oxide synthase inhibitor) on kinematic parameters of ram epididymal spermEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, physiology of sperm motility in rams is affected by nitric oxide, although, exogenous NO does not increase sperm motility. Excess NO may initiate toxic conditions resulting in decreased sperm motility. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00580-009-0911-yAuthors Hossein Hassanpour, Shahrekord University Department of Basic Sciences, Faculty of Veterinary Medicine Shahrekord IranMasood Teshfam, Islamic Azad University, Science and Research Campus Department of Physiology, Faculty of Specialized Veterinary Sciences Tehran IranAli Karimi Goodarzi, Islamic Azad University, Kar...
Source: Comparative Clinical Pathology - September 29, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Purification and kinetic study of bone and liver alkaline phosphatase isoenzymes in the dogEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  To study bone and liver alkaline phosphatases (ALP) in the dog, tissue samples were obtained immediately after death from dogs apparently involved in road traffic accidents. Tissue samples were homogenized, and extracted protein was subjected to diethylaminoethyl cellulose–Sephadex column chromatography equilibrated previously with 0.01 M Tris-hydrochloric acid buffer (pH 7.2) and eluted with linear gradient of ionic strength from 0 to 0.4 M NaCl. Fractions with peak activity of ALP were considered a source of purified enzyme. ALP activity was measured by a kinetic method using p-nitroph...
Source: Comparative Clinical Pathology - September 29, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Haematology of captive grey-brocket deer Mazama gouazoubira (Fischer, 1814) (Cervidae: Odocoileinae)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Reference intervals for haematologic and total plasma proteins profiles were determined for 11 physically restrained adult grey-brocket deer. Erythrocytic alterations, as discrete to moderate poikilocytosis, were observed in all animals. Red and white blood cells counts were determined by manual methodology. Obtained erythron and leukon values were slightly higher than previous reports. Statistical difference was not demonstrated between stags and hinds. No previous studies reported blood values for captive grey-brocket deer obtained by manual methods. Also, the authors suggest that future studies o...
Source: Comparative Clinical Pathology - September 24, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

The acute and subchronic toxicity studies of aqueous leaf and stem bark extract of Costus afer ker (Zingiberaceae) in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  This work investigated the acute and subchronic toxicity profile of aqeous stem bark and leaf extract of Costus afer ker (Zingiberaceae). This plant is used extensively for food, economic, and medicinal purposes in Nigeria. Acute oral toxicity studies in male and female mice did not produce any sign of acute toxicity or death even at the dose of 4,000 mg/kg. Thirty-six albnino Wistar mice of varied sexes weighing between 28 and 35 g were divided into four groups. Groups A, B, and C were given different concentrations of the extract at 20, 13.33, and 6.67 mg/ml, respectively in water. G...
Source: Comparative Clinical Pathology - September 23, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Effect of experimental feeding of Codiaeum variegatum leaves on growth, hematology, gonadal, and extra-gonadal sperm reserves of adult albino ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study has shown that feeding male rats in particular and probably other animals in general on the leaves of garden croton at a level as low as 0.25% level of supplementation has the tendency to stimulate the immune function of animals but could severely reduce the testicular and epididymal sperm reserve counts, thereby reducing the reproductive efficiency of male animals. These results recommend further studies in respect to the immunostimulating and spermatotoxic properties of the leaves of this plant. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00580-009-0894-8Authors Shoyinka S. V. Ol...
Source: Comparative Clinical Pathology - September 18, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Effects of rearing temperature on hematological and biochemical parameters of great sturgeon (Huso huso Linnaeus, 1758) juvenileEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The effect of environmental temperature changes on hematological and biochemical parameters of Huso huso juveniles was studied. Six-month-old juveniles with mean body weight of 69.2 ± 4.1 g were subjected to different temperatures (9–14°C, 15–20°C, and 21–26°C, respectively). The hematological parameters, ion Ca2+, glucose, and the cortisol concentrations were assessed after a period of 21 days rearing at these temperatures. The results show that hematocrit, Ca2+, and eosinophil were affected by different temperatures. Increasing temperature led to a significant increase (P &...
Source: Comparative Clinical Pathology - September 3, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Determination of some normal serum parameters in starry sturgeon (Acipenser stellatus Pallas, 1771) during spring seasonEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Hematology can be a useful tool for monitoring health status, detecting illnesses, and following the progress of diseases and responses to therapy. Despite advances in fish medicine in recent years, interpretation of fish hematology is often hampered by lack of meaningful reference values and the bewildering diversity of fish species. Serum samples of 40 Acipenser stellatus fish were analyzed (20 male and 20 female) and their serum parameter values were measured in both sexes. Serum biochemical values were determined (mean ± SEM) for sodium (Na; 149.2 ± 1.917 mmol/l), potassium (K; 2.7...
Source: Comparative Clinical Pathology - August 28, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Haematology of great sturgeon (Huso huso Linnaeus, 1758) juvenile exposed to brakish water environmentEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The effect of environmental salinity on haematological parameters of Huso huso juvenile was studied. Five-month-old juveniles (mean body weight of 28.3 ± 2.1 g) were subjected to 0, 3, 6, 9 and 12 ppt salinities. Fish were adapted to salinity by increasing water salinity at a rate of 2 ppt per day. The haematological parameters were assessed after a period of 20 days rearing at these salinities. Increasing salinity affected some blood characteristics. After transfer from fresh water to brackish water, red blood cells, haematocrit, haemoglobin and mean corpuscular haemoglobin ...
Source: Comparative Clinical Pathology - August 28, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Bone-specific alkaline phosphatase activity in dairy cowsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, 75 healthy Holstein dairy cows in their first, second, third, fourth or fifth parities underwent serum bone-specific alkaline phosphatase quantification. The results indicate that enzyme activity values have a decreasing pattern with increasing order of parity (p < 0.05). However, the differences between cows in second and third parity and also between cows in fourth and fifth parity were not statistically significant (p > 0.1). We concluded that bone-specific alkaline phosphatase measurement by heat inactivation provides a simple method to determine bone metabolic status and useful data t...
Source: Comparative Clinical Pathology - August 27, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Haematology of great sturgeon (Huso huso Linnaeus, 1758) juvenile exposed to clove powder as an anaestheticEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The anaesthetic effects of clove powder were studied in juvenile great sturgeon. Haematological parameters were assessed before, immediately after and 24 h after 10 min of anaesthesia using clove powder at 175, 225, 275 and 350 mg/L concentrations. The 10-min exposure to clove powder caused a significant increase (P < 0.05) in the haematocrit, haemoglobin and total erythrocyte count after anaesthesia. These values returned back to normal within 24 h. Clove powder anaesthesia had no effect on any other haematological parameter measured. Results of the examinations suggest t...
Source: Comparative Clinical Pathology - August 27, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Relationship between the blood thyroid hormones and lipid profile in Moghani sheep; influence of age and sexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The aim of this study was to determine the correlation between thyroid hormones and lipid profile in blood of Iranian Moghani sheep in different ages and sexes. Blood samples were taken from the jugular vein of 260 clinically healthy and nonpregnant animals in eight age groups (1–14 days, 1–2, 2–3, 3–6, 6–12, 12–24, 24–48, and  > 48 months) in autumn. The plasma was analyzed to determine thyroxine (T4), triiodothyronine (T3), free thyroxine (fT4), free triiodothyronine (fT3), cholesterol, triglyceride, high-density lipoprotein (HDL-cholesterol), low-density lipoprotein ...
Source: Comparative Clinical Pathology - August 27, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Haematological and haematochemical responses to training and competition in standardbred horsesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The aim of this study was to evaluate haematological and haematochemical responses to training and competition in standardbred horses. We investigated the modifications that occur in athletic horses during different workloads of training and after official competitions of 1,600 and 2,000 m. The study was carried out on 15 gelding clinically healthy horses. The animals were divided into three groups: group A, group B, and group C. All animals of group A were subjected to two training schedules with different workloads. Group B took part in a 1,600 m trot official competition, and group C to...
Source: Comparative Clinical Pathology - August 25, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Detection of Staphylococcus aureus in milk by PCREmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The aim of this study was to compare the detection of Staphylococcus aureus (S. aureus) in raw milk samples by polymerase chain reaction (PCR) with detection by cultural methods. A total of 100 milk samples were collected from individual cattle in industrial dairy herds in Urmia, Iran. DNA was extracted from all samples directly. PCR amplifications were performed with a pair of primers specific for the coa gene of S. aureus. In order to isolate S. aureus by cultural methods, bacteriological examinations were done on all samples. Of the 100 milk samples tested, 14% were positive on the basis of the cu...
Source: Comparative Clinical Pathology - August 24, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Serological evidence of canine monocytic ehrlichiosis in IranEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract   Ehrlichia canis has a worldwide geographic distribution, but little is known about the occurrence of Canine monocytic ehrlichiosis (CME) in Iran. The current study was carried out to evaluate the seroprevalence and factors associated with a positive antibody response to E. canis in dogs from Kerman city, southeast of Iran. One hundred and twenty-three privately owned dogs were chosen from apparently healthy animals referred to veterinary hospital for health check or vaccination. All dogs were subjected to physical, hematological, and biochemical examinations and serological tests. Indirect immunof...
Source: Comparative Clinical Pathology - August 24, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Clinical aspects of cats experimentally infected with Trypanosoma evansiEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The aim of this study was to evaluate clinical signs of cats experimentally infected with Trypanosoma evansi. Thirteen adult female nonbreeding Felix catus were separated into two groups: seven animals were infected with 108 trypomastigotes each, and six animals were used as negative controls. Blood smears were performed daily for 56 days. Cardiorespiratory frequency was observed weekly, and blood samples for hematocrit analyses were collected at 15-day intervals. The protozoan was found in the blood 24 to 48 hours post-inoculation and irregular peaks of parasitemia were observed. Hematocrit sign...
Source: Comparative Clinical Pathology - August 24, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

The therapeutic potential of thiamine for treatment of experimentally induced subacute lead poisoning in sheepEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, the efficacy of thiamine on blood and tissue lead contents was evaluated in subclinical lead toxicosis in sheep. Nine female sheep weighing 25–29 kg were orally receiving a daily dose of 80 mg/kg body weight of lead acetate for 5 days. Then, the animals were assigned into two groups. Group 1 did not receive any further treatment and was used as the control group, and group 2 was treated intravenously by 25 mg/kg body weight of thiamine twice daily for 7 days. Within 1 day following treatment, in the treated group, blood lead level (mean 243.5 Î¼g/l) was significantly...
Source: Comparative Clinical Pathology - August 24, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

The effects of fresh garlic on the serum concentration of total cholesterol, total triglyceride and adipose tissues of broilersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  The aim of this study was to investigate the effects of garlic on total cholesterol, total triglyceride and adipose tissues in chickens, since garlic is typically used as a dietary supplement in broilers' diets. One hundred male broiler chicks were divided randomly into two groups. From the day after they were born, group one received standard feed plus 20 kg/ton dried fresh garlic and group two received just standard feed without added garlic. On day 50, the chickens were individually weighed and slaughtered. Carcasses and adipose tissues were weighed out separately. During the slaughtering pr...
Source: Comparative Clinical Pathology - August 24, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Successful management of refractory psychomotor seizures with gabapentin and phenobarbital in a Doberman pinscher dogEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Gabapentin is a new antiepileptic drug which is used in humans with complex partial epilepsy. Recently, two published studies described the efficacy of gabapentin in dogs with refractory epilepsy. However, clinical application of gabapentin in dogs with refractory psychomotor seizure has not been documented. The present report describes a 2-year-old male Doberman pinscher dog with a history of recurrent bizarre behaviors such as aggression, circling, and flank-biting. Initial oral administration of phenobarbital resulted in resolution of psychomotor seizures, but 3 months after the initial pres...
Source: Comparative Clinical Pathology - August 20, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Four kinds of hypothyroidism and the cancers of breast and lung found in cases of Japanese rheumatoid arthritis (RA), arthritis deformans, or bone fractureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Japanese patients were selected from 875 patients who had undergone an orthopedic operation. Seventy-two cases of rheumatoid arthritis (RA) and 17 cases of suspected RA were analyzed. In parallel with high levels of rheumatoid factor (RF), Sjoegren syndrome, finger and toe deformans, and knee and hip arthritis deformans were observed at high frequencies. The arthritis deformans of 51 patients displayed a mean serum iron levels of 50 ± 33 (SD) μg/dl and transferrin saturation (TS) of 18 ± 11%. The hypothyroidisms diagnosed in the 12 patients were caused by autoimmune, hypopituitary, and pa...
Source: Comparative Clinical Pathology - August 20, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Changes in the pathogenicity of relapsed diminazene aceturate (DA)-resistant Trypanosoma brucei brucei as the trypanosomes are transmitted from DA-treated hosts to another set of animalsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study investigated the changes in pathogenicity of relapsed diminazene aceturate (DA)-resistant Trypanosoma brucei brucei (TBB) as the trypanosomes are transmitted from DA-treated hosts to another set of animals. The Federe strain of T. brucei brucei which was known to be DA resistant was used to infect two groups of rats, one of which was treated at the peak of infection. There was temporary clearance of the trypanosomes from blood of the treated group and subsequent relapse of the infection. The relapsed trypanosomes were used to infect a group of rats (group A1), and the pathogenicity of the relapsed T. brucei br...
Source: Comparative Clinical Pathology - August 19, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Nodular dermatitis as an atypical form of canine demodicosis in an English bulldogEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  This case report describes the unusual clinical findings in a 2-year-old English bulldog with generalized demodicosis. The dog was referred with a 2-month history of generalized pruritus, alopecia, lichenification, and nodular lesions. A complete series of dermatologic tests such as Wood's light examination, direct microscopic examination, and fungal culture were performed. In the deep skin scrapings Demodex canis was identified by microscopic examination. A punch biopsy was taken from nodules and histological examination revealed that the large numbers of mites were located both in the lumen of hair...
Source: Comparative Clinical Pathology - August 19, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Effects of alcohol consumption on experimental Trypanosoma brucei brucei infection in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  Forty-two 3-week-old inbred albino mice were used to study the effect of alcohol consumption on experimental Trypanosoma brucei brucei (T. b. brucei) infection in mice. They were divided into three groups of 14 mice each. Group 1 mice received graded levels of ethanol at 10%, 20%, and 30% (v/v) in water for 1 week, 2 weeks, and the rest of the experimental period, respectively. At day 29 of the experiment, 1 ml of normal saline diluted blood of mice containing approximately 3.0 × 106 T. b. brucei was given intraperitoneally to the mice in groups 1 and 2 (non alcohol-exposed). Gr...
Source: Comparative Clinical Pathology - August 19, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Effect of xylazine–ketamine–diazepam anesthesia on certain clinical and arterial blood gas parameters in sheep and goatsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study was conducted to evaluate the effect of xylazine–ketamine–diazepam anesthesia on heart rate, respiration rate, rectal temperature, rumen motility, peripheral blood pH, PaO2, and PaCO2 in adult female nonpregnant Awassi sheep and adult female nonpregnant Damascus goats. Anesthesia was induced using 0.1 mg/kg, 5 mg/kg, and 0.25 mg/kg xylazine, ketamine, and diazepam respectively as a single intravenous injection. The heart rate, respiration rate, rectal temperature, rumen motility, peripheral arterial blood pH, PaO2, and PaCO2 were evaluated 15 min before and at 15, 30, and 60 min ...
Source: Comparative Clinical Pathology - August 19, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

The importance of publishing laboratory observations—reply to Camus and KrimerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory EditorialDOI 10.1007/s00580-009-0890-zAuthors Andrew K. Davis, The University of Georgia D.B. Warnell School of Forestry and Natural Resources Athens GA 30602 USAKerry Holcomb, The University of Georgia D.B. Warnell School of Forestry and Natural Resources Athens GA 30602 USA Journal Comparative Clinical PathologyOnline ISSN 1618-565XPrint ISSN 1618-5641 (Source: Comparative Clinical Pathology)
Source: Comparative Clinical Pathology - August 17, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Evaluation of the immunostimulatory activity of Ziziphora tenuior extractsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, Z. tenuior extract demonstrated significant immunostimulatory activity using MTT, NBT, and killing assays on Candida albicans. To clarify the exact machanisms of this activity, more studies should be performed with isolated immunostimulatory components. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00580-009-0885-9Authors Alireza Naeini, Shahed University Department of Mycology, Faculty of Medicine Tehran IranAlireza Khosravi, University of Tehran Mycology Research Center, Faculty of Veterinary Medicine Azadi Street P.O. Box: 14155-6453 Tehran IranHassan Tadjbakhsh, University of Teh...
Source: Comparative Clinical Pathology - August 17, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

In vitro effects of pentoxifylline on kinematic parameters, capacitation, and acrosome reaction of ram epididymal spermEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, a low concentration of pentoxifylline was able to increase most kinematic parameters while high concentration had the opposite effect. Pentoxifylline in high concentration increased capacitation but decreased acrosome reaction. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00580-009-0882-zAuthors Hossein Hassanpour, Shahrekord University Department of Basic Sciences, Faculty of Veterinary Medicine Saman St Shahrekord IranPezhman Mirshokraei, Shahrekord University Department of Clinical Sciences, Faculty of Veterinary Medicine Shahrekord IranParviz Tajik, University of Tehran Depart...
Source: Comparative Clinical Pathology - August 17, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Histopathologic features of a unilateral renal dysplasia in a cat (Felis domestica)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study shows congenital renal dysplasia that was detected in a stray cat. The present report describes the primary microscopic features that are essential to renal dysplasia diagnosis. Histopathologic examination showed a narrow renal cortex, decreased numbers of glomeruli, underdeveloped glomeruli, marked medullary mesenchymal connective tissue, and disorganized primitive tubules in the cortex and medulla. It is the first report of this anomaly that explains microscopic lesions of renal dysplasia in cat. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00580-009-0883-yAuthors Shahrzad Azizi,...
Source: Comparative Clinical Pathology - August 12, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

Therapeutic effect of cimetidine on acetaminophen-induced nephrotoxicity in rabbitsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, 120 female rabbits were randomized into 12 groups (three control and nine test groups). The LD50 of acetaminophen was calculated to be 3.24 g/kg, and a suspension at this concentration was administered orally to induce renal necrosis. Three treatment groups received a single dose of cimetidine (40 mg/kg) administered intravenously at 0, 2, or 4 h after administration of acetaminophen depending upon treatment group. The six remaining treatment groups received cimetidine in two equal doses of 20 mg/kg administered at 0 and 12 h, 0 and 24 h, 2 and 12 h, 2 and 24 h, 4 ...
Source: Comparative Clinical Pathology - August 12, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals

A bilateral ovarian psammomatous papillary cystic adenocarcinoma in a German Shepherd bitchEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract  A 14-year-old, 30-kg, intact female, German Shepherd was presented with a history of lethargy, anorexia, decreased body condition, dyspnoea, enlarged abdomen and abnormal oestral manifestation. The dog was then referred for further and complete clinical evaluation. On physical evaluation, the dog was depressed, dyspnoic, slightly dehydrated and the abdomen was distended with a positive succussion; an abdominal effusion was presumed. Disseminated peritoneal carcinomatosis with multi-organ metastasis and bilateral ovarian cystic papillary adenocarcinoma was diagnosed. Multiple psammoma bodies were als...
Source: Comparative Clinical Pathology - August 12, 2009 Category: Pathology Tags: Comparative Clinical Pathology Source Type: journals