Directional Analysis of Cardiac Motion Field from Gated Fluorodeoxyglucose PET images using the Discrete Helmholtz Hodge Decomposition
Cardiovascular diseases (CVDs) represent a significant risk of death. In 2012 an estimated 17.5 million people died from CVDs in 2012, which is 31% of global deaths, according to the World Health Organization1) (WHO, 2012). Since CVDs can cause a change to normal cardiac motion, quantification and analysis of the cardiac motion field may assist in diagnosis. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - June 29, 2017 Category: Radiology Authors: J.A. Sims, M.C. Giorgi, M.A. Oliveira, J.C. Meneghetti, M.A. Gutierrez Source Type: research

Abdominal Parametric Perfusion Imaging with Respiratory Motion-Compensation based on Contrast-enhanced Ultrasound: in-vivo Validation
(Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - June 21, 2017 Category: Radiology Authors: Diya Wang, Mengnan Xiao, Yu Zhang, Mingxi Wan Source Type: research

Deep convolutional neural networks for automatic classification of gastric carcinoma using whole slide images in digital histopathology
This study explores deep learning methods for computer-aided classification in H&E stained histopathological whole slide images of gastric carcinoma. An introductory convolutional neural network architecture is proposed for two computerized applications, namely, cancer classification based on immunohistochemical response and necrosis detection based on the existence of tumor necrosis in the tissue. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - June 16, 2017 Category: Radiology Authors: Harshita Sharma, Norman Zerbe, Iris Klempert, Olaf Hellwich, Peter Hufnagl Source Type: research

A Level-set Approach to Joint Image Segmentation and Registration with Application to CT Lung Imaging
Image registration and segmentation techniques are fundamental components of medical image analysis as they form the basis for many advanced frameworks for computerized understanding of medical imaging. For example, registration and segmentation of X –ray Computed Tomography (CT) can be used for a vast range of emerging pulmonary applications (Schnabel et al., 2016). Such applications in current and developing medical practice include: personalized adjustment of image-guided radiation therapy (IGRT) (Xing et al., 2006), assessment of disease a nd treatment progression, e.g. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - June 15, 2017 Category: Radiology Authors: Piotr Swierczynski, Bart łomiej W. Papież, Julia A. Schnabel, Colin Macdonald Source Type: research

Automatic quantification of IHC stain in breast TMA using colour analysis
Immunohistochemical (IHC) biomarkers in breast tissue microarray (TMA) samples are used daily in pathology departments. In recent years, automatic methods to evaluate positive staining have been investigated since they may save time and reduce errors in the diagnosis. These errors are mostly due to subjective evaluation. The aim of this work is to develop a density tool able to automatically quantify the positive brown IHC stain in breast TMA for different biomarkers. To avoid the problem of colour variation and make a robust tool independent of the staining process, several colour standardization methods have been analyse...
Source: Computerized Medical Imaging and Graphics - June 13, 2017 Category: Radiology Authors: M. Milagro Fern ández-Carrobles, Gloria Bueno, Marcial García-Rojo, Lucía González-López, Carlos López, Oscar Déniz Source Type: research

Elimination of White Gaussian Noise in Arterial Phase CT Images to Bring Adrenal Tumours into the Forefront
(Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - June 4, 2017 Category: Radiology Authors: Hasan Koyuncu, Rahime Ceylan Source Type: research

The 3D Pelvic Inclination Correction System (PICS): A universally applicable coordinate system for isovolumetric imaging measurements, tested in women with pelvic organ prolapse (POP)
Reference systems are widely used in medicine to classify physiologic and pathologic conditions. Each is specifically to be relevant for the joint or body part of interest and the questions to be asked (Wu and Cavanagh, 1995). The pelvic organs are complex, three-dimensional structures, dispersed in space within the bony pelvis. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - June 3, 2017 Category: Radiology Authors: Caecilia S. Reiner, Tom Williamson, Thomas Winklehner, Sean Lisse, Daniel Fink, John O.L. DeLancey, Cornelia Betschart Tags: Original research Source Type: research

Editorial board and publication information
(Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - June 1, 2017 Category: Radiology Source Type: research

Application of eye tracking in medicine: A survey, research issues and challenges
The performance and quality of medical procedures and treatments are inextricably linked to technological development. The application of more advanced techniques provides the opportunity to gain wider knowledge and deeper understanding of the human body and mind functioning. The eye tracking methods used to register eye movement to find the direction and targets of a person's gaze are well in line with the nature of the topic. Such information is useful not only in revealing abnormalities in eye functioning and thus ensuring appropriate therapy but also in cognitive studies focused on learning about peoples ’ emotions, ...
Source: Computerized Medical Imaging and Graphics - May 30, 2017 Category: Radiology Authors: Katarzyna Harezlak, Pawel Kasprowski Source Type: research

Information Granules in Image Histogram Analysis
Widely understood information plays an important role in different communication processes. Digital information, which may represent text, sounds, images, videos and many others is of particular importance. Among the terms associated with digital information are acquisition, storage and processing. The processing of information often involves the extraction of substantial information parts. The concepts of information granule and granular computing appear to be very helpful. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - May 10, 2017 Category: Radiology Authors: Wojciech Wieclawek Source Type: research

Fully Automatic Segmentation of Left Ventricular Anatomy in 3-D LGE-MRI
About 26 million people worldwide are suffering from heart failure (HF) (Ponikowski et al., 2014). The symptoms of HF typically include shortness of breath, signs of fluid retention, fatigue, exercise intolerance, and depression (Shea and Sweeney, 2003). The underlying cardiac cause of HF is most often a myocardial infarction (McMurray et al., 2012). According to Dickstein et al. (2009) at least 51% of patients suffering from HF have an ischemic history. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - May 8, 2017 Category: Radiology Authors: Tanja Kurzendorfer, Christoph Forman, Michaela Schmidt, Christoph Tillmanns, Andreas Maier, Alexander Brost Source Type: research

Transfer Learning on Fused Multiparametric MR Images for Classifying Histopathological Subtypes of Rhabdomyosarcoma
Rhabdomyosarcoma (RMS) represents the most common extracranial solid malignancy in children and adolescents with an age of less than 20 years(Ognjanovic et al., 2009). The majority of RMS is of embryonal (ERMS) and alveolar (ARMS) subtypes. Patient outcomes vary considerably, with 5 years survival rates between 35% and 95% depending on the type of RMS involved, tumor grade, tumor stage and patient age, among other factors (Malempati and Hawkins, 2012). Most ARMS are more aggressive than ERMS and require more intense treatment. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - May 5, 2017 Category: Radiology Authors: Imon Banerjee, Alexis Crawley, Mythili Bhethanabotla, Heike E Daldrup-Link, Daniel L. Rubin Source Type: research

Virtual bacterium colony in 3D image segmentation
Image processing and analysis is a widely developed and used engineering activity nowadays. On one hand, civilization of the first decades of the 21st century is a more picture-based civilization than ever, mainly due to globalization mechanisms and expansion of social networks. On the other hand, the rapid and symbiotic growth of medicine and technique produces terabytes of imaging data of various modalities, like computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), or ultrasonography (US). (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - April 26, 2017 Category: Radiology Authors: Pawel Badura Source Type: research

An adaptive positivity thresholding method for automated Ki67 hotspot detection (AKHoD) in breast cancer biopsies
The proliferative activity of breast cancer tissue can be estimated using the Ki67 biomarker. The percentage of positivity of such biomarker is correlated with proliferation and consequently with the prognosis of a breast tumor. Ki67 marked tissue samples are analyzed by an experienced pathologist who identifies the most active areas of tumor cell proliferation called hotspots, and estimates the positivity of each case.A method for the Automated Ki67 Hotspot Detection (AKHoD) is presented in this work. (Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - April 24, 2017 Category: Radiology Authors: David Pilutti, Vincenzo Della Mea, Enrico Pegolo, Francesco La Marra, Fulvio Antoniazzi, Carla Di Loreto Source Type: research

Accurate 3D Reconstruction of Bony Surfaces Using Ultrasonic Synthetic Aperture Techniques for Robotic Knee Arthroplasty
(Source: Computerized Medical Imaging and Graphics)
Source: Computerized Medical Imaging and Graphics - April 19, 2017 Category: Radiology Authors: William Kerr, Philip Rowe, Stephen Gareth Pierce Source Type: research