Skin Grafting for Dermatologists: Past, Present, and Future
ConclusionSkin grafting is a complex procedure that requires careful planning and postoperative care. Success depends on factors like the type of graft, wound management, and overall health of the patient. Skin grafting has evolved with advancements in surgery, anesthesia, and wound care and remains a crucial technique for restoring function and appearance. (Source: Current Dermatology Reports)
Source: Current Dermatology Reports - April 9, 2024 Category: Dermatology Source Type: research
Symmetrical Drug-Related Intertriginous and Flexural Exanthem-Like Eruption Post-COVID-19 Vaccination: A Case Report and Review of the Literature
AbstractPurpose of ReviewSDRIFE (Symmetrical drug-related intertriginous and flexural exanthema) is type IV hypersensitivity drug-related skin eruption. Numerous drugs have previously been associated with SDRIFE; however few cases associated with the coronavirus disease 2019 (COVID-19) vaccine have been reported. Here, we present a case in which SDRIFE was generated following administration of the CoronaVacTM (SinoVac Biotech Corporation) vaccine. A literature review was also conducted to summarize the various cases of SDRIFE induced by the coronavirus disease 2019 (COVID-19) vaccine.Recent FindingsSDRIFE is a rare complic...
Source: Current Dermatology Reports - March 28, 2024 Category: Dermatology Source Type: research
Exploring Therapeutic Approaches for Vitiligo: An Inclusive Review from Translational Modalities to Alternative Therapies
AbstractPurpose of ReviewThe primary objective of this extensive literature review was to explore emerging therapeutic modalities for Vitiligo, with the aim of identifying promising avenues for treatment. These modalities encompass various techniques such as melanocyte transplantation for repopulation and innovative pharmacological interventions aimed at modulating immune responses. This review aims to shed light on the theories underlying Vitiligo pathogenesis and evaluate the efficacy of a range of therapeutic interventions and preventive measures associated with the condition.Recent FindingsCutting-edge research in the ...
Source: Current Dermatology Reports - March 14, 2024 Category: Dermatology Source Type: research
Oral Psoriasis —An Overlooked Entity: Current Paradigms and Future Perspectives
AbstractPurpose of ReviewPsoriasis is a chronic, genetically determined, scaly, and inflammatory disease of the skin. Pathogenesis is multi-factorial, involving dysregulated inflammation and genetic associations. Cutaneous lesions are characterized as thick, erythematous, all-around defined plaques covered with a silvery white scale. Commonly affected areas include the elbows, knees, sacral area, and scalp. One of the factors that may result in the appearance of psoriatic lesions may be the oral cavity lesions. Aim of the present article was to review the effects of psoriasis on oral cavity, histopathological investigation...
Source: Current Dermatology Reports - March 2, 2024 Category: Dermatology Source Type: research
The Use of Timolol for Wound Healing—A Review
AbstractPurpose of ReviewIn recent years, drug repurposing has gained traction as a method to accelerate the availability of effective treatments. This review focuses on timolol, originally a topical non-selective β-adrenergic antagonist used for increased intraocular pressure and glaucoma, and its emerging role in the wound healing landscape—a field that has been lacking in effective treatments for decades.Recent FindingsPreclinical and clinical studies have highlighted timolol ’s promise as a therapeutic option in wound healing. Its benefits are attributed to various mechanisms including improved re-epithelial...
Source: Current Dermatology Reports - February 22, 2024 Category: Dermatology Source Type: research
Deroofing: A Practical Guide for the Dermatologist
AbstractPurpose of ReviewHidradenitis suppurativa is a chronic inflammatory skin condition marked by significant structural changes such as nodules, abscesses, and subcutaneous tunnels, often accompanied by drainage and pain. Medical treatment alone usually does not suffice for optimal disease control. Therefore, surgical interventions, particularly for moderate-to-severe cases with tunnel formation, are a crucial adjunct to medical therapy. This paper aims to outline a practical approach to deroofing in hidradenitis suppurativa, covering the necessary materials, surgical approach, wound care, common complications, and fre...
Source: Current Dermatology Reports - February 15, 2024 Category: Dermatology Source Type: research
Foam Dressings for Wound Healing
AbstractPurpose of ReviewChronic, non-healing wounds affect millions of people globally and demand significant healthcare spending. One of the most important aspects of wound care is the appropriate selection and placement of a wound dressing. One of the key roles of a wound dressing is the optimization of a moist wound environment for healing. A moist wound environment facilitates wound healing by encouraging interaction of growth factors with their targets, epithelialization, angiogenesis, and autolytic debridement of dead tissue. However, while some chronic wounds are highly exudative and require absorptive dressings in...
Source: Current Dermatology Reports - February 13, 2024 Category: Dermatology Source Type: research
Innovative Immunotherapy for the Treatment of Atopic Dermatitis: Focus on the European and Latin American Regulatory Frameworks
AbstractPurpose of ReviewThis review focused on the mechanisms of action, safety profiles, and efficacy of new and promising systemic immunological treatments for AD. In particular, it has been highlighted how new treatments ’ targets participate in the pathogenic mechanisms of AD. The introduction of new pharmacological agents can provide new therapeutic options, but there is the need to evaluate how “narrow-acting” agents like individual interleukin inhibitors will perform under the safety and efficacy profiles compared with “broad-acting” agents like JAK inhibitors. Furthermore, the article aimed to describe a...
Source: Current Dermatology Reports - February 9, 2024 Category: Dermatology Source Type: research
