Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
Outcomes of Total Hip Arthroplasty Performed for HIV-Associated Osteonecrosis in China: A Retrospective Cohort Study
CONCLUSION: THA is safe and effective in Chinese AIDS patients with ONFH. However, optimal treatment has limited efficacy in AIDS patients undergoing THA for ONFH. The reconsideration and evaluation of the predictive value of CD4+ T lymphocytes for postoperative complications in joint replacement procedures is warranted.PMID:38638043 | DOI:10.2174/011570162X302889240408033958 (Source: Current HIV Research)
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Kangpeng Li Rui Ma Rugang Zhao Qiang Zhang Source Type: research
The Hidden Enemy Within: Uncovering the Secrets of HIV Tissues Reservoirs and Current mRNA Vaccine Development
Curr HIV Res. 2024 Apr 18. doi: 10.2174/011570162X301593240409072840. Online ahead of print.ABSTRACTHuman Immunodeficiency Viruses (HIV) continue to pose a significant global health threat despite the availability of antiretroviral therapy (ART). As a retrovirus, HIV persists as a stable, integrated, and replication-competent provirus within a diverse array of long-lived cells for many years, often termed "latent reservoirs" in individuals. Thus, this review aims to furnish a comprehensive overview of diverse tissue reservoirs where HIV persists, elucidating their pathogenesis and advancement in their strategies for clinic...
Source: Current HIV Research - April 19, 2024 Category: Infectious Diseases Authors: Satyendra Prakash Mayank Kumar Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
Discovery of Ten Anti-HIV Hit Compounds and Preliminary Pharmacological Mechanisms Studies
CONCLUSION: A drug screening system using Rev-A3R5-GFP reporter cells with pseudoviruses (pNL4-3) is highly efficient. This study provided potential hit compounds for new HIV drug research.PMID:38532605 | DOI:10.2174/011570162X301289240320082840 (Source: Current HIV Research)
Source: Current HIV Research - March 27, 2024 Category: Infectious Diseases Authors: Yushan Lian Zhimin Huang Xinyi Liu Zhicheng Deng Dan Gao Xiaohui Wang Source Type: research
