Identification of Critical Genes Differentiating Stable and Unstable Atherosclerotic Plaques: A Bioinformatic and Computational Analysis
CONCLUSION: The present study used several datasets to identify key genes associated with stable and unstable atherosclerotic plaque.PMID:38639275 | DOI:10.2174/0115701611282362240409035233 (Source: Current Vascular Pharmacology)
Source: Current Vascular Pharmacology - April 19, 2024 Category: Drugs & Pharmacology Authors: Maryam Mahjoubin-Tehran Raul D Santos Wael Almahmeed Khalid Al-Rasadi Amirhossein Sahebkar Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research

Statins and Venous Thromboembolic Disease - Where are we Now?
Curr Vasc Pharmacol. 2024 Mar 4. doi: 10.2174/0115701611308323240229050237. Online ahead of print.ABSTRACTClassical risk factors for atherosclerosis also play a role in the pathogenesis of venous thromboembolism (VTE). Low-density lipoprotein cholesterol has prothrombotic and endothelium- deteriorating effects which are not limited to the arterial system. The association between hypercholesterolemia and VTE has been established, but the benefits of statins in the prevention of VTE assessed by observation studies seemed equivocal. The large, randomized trial Justification for the Use of Statins in Prevention: an Interventio...
Source: Current Vascular Pharmacology - March 5, 2024 Category: Drugs & Pharmacology Authors: Pavel Poredo š Debabrata Mukherjee Ale š Blinc Source Type: research