Increased IL-22 in cerebrospinal fluid of neuro-beh çet's disease patients
In conclusion, these results suggest that IL-6 contributes to the production of IL-22 by T cells leading to the exacerbation of inflammation and damage within the CNS of NBD patients.PMID:38631183 | DOI:10.1016/j.cyto.2024.156617 (Source: Cytokine)
Source: Cytokine - April 17, 2024 Category: Molecular Biology Authors: Meriam Belghith Olfa Maghrebi Rafika Ben Laamari Mariem Hanachi Sana Hrir Zakaria Saied Samir Belal Adel Driss Samia Ben Sassi Thouraya Boussoffara Mohamed-Ridha Barbouche Source Type: research

Serum levels of sirtuins, leptin and adiponectin in women with pregnancy-induced hypertension
CONCLUSIONS: High leptin levels in PIH women during 3rd trimester might be helpful to predict the necessity for a caesarian section. Blood levels of sirtuins 1, 3 and 6 measured after the 20th week of gestation cannot be regarded as a single diagnostic test for PIH or preeclampsia. More studies to clarify significance of sirtuins in PIH and PE development and diagnosis are needed.PMID:38631184 | DOI:10.1016/j.cyto.2024.156612 (Source: Cytokine)
Source: Cytokine - April 17, 2024 Category: Molecular Biology Authors: Magdalena Gola ńska-Wróblewska Jolanta Fryczak Agnieszka Siejka Source Type: research

Multi-species synbiotic supplementation increased fecal short chain fatty acids and anti-inflammatory cytokine interleukin-10 in adult men with dyslipidemia; A randomized, double-blind, clinical trial
CONCLUSIONS: A Twelve-week synbiotic supplementation increased fecal SCFAs and improved inflammation in adult men with dyslipidemia.PMID:38631185 | DOI:10.1016/j.cyto.2024.156608 (Source: Cytokine)
Source: Cytokine - April 17, 2024 Category: Molecular Biology Authors: Shekoufeh Salamat Alireza Jahan-Mihan Lida Gharibvand Mohammad Reza Tabandeh Anahita Mansoori Source Type: research

Targeting TNF- α-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach
CONCLUSION: The findings of this study suggested that TNF-α promotes the differential expression of pro-inflammatory cytokines, TTR, and RAGE via NF-kB pathways activation. Anti-inflammatory effect of apigenin impedes TNF-α mediated dysregulation or expression associated with RA pathogenesis.PMID:38626647 | DOI:10.1016/j.cyto.2024.156616 (Source: Cytokine)
Source: Cytokine - April 16, 2024 Category: Molecular Biology Authors: None Monu Prachi Agnihotri Mohd Saquib Sagarika Biswas Source Type: research

Targeting TNF- α-induced expression of TTR and RAGE in rheumatoid arthritis: Apigenin's mediated therapeutic approach
CONCLUSION: The findings of this study suggested that TNF-α promotes the differential expression of pro-inflammatory cytokines, TTR, and RAGE via NF-kB pathways activation. Anti-inflammatory effect of apigenin impedes TNF-α mediated dysregulation or expression associated with RA pathogenesis.PMID:38626647 | DOI:10.1016/j.cyto.2024.156616 (Source: Cytokine)
Source: Cytokine - April 16, 2024 Category: Molecular Biology Authors: None Monu Prachi Agnihotri Mohd Saquib Sagarika Biswas Source Type: research

The sex-dependent impact of adipose tissue and inflammation on chronic pain - A cross-sectional study from the all of us research program
This article investigates the relationship between chronic pain, obesity, and inflammatory markers. It could help elucidating sex difference in pain mechanisms, as well as the risk factors for chronic pain, potentially improving patient diagnosis, follow-up and treatment.PMID:38621331 | DOI:10.1016/j.cyto.2024.156614 (Source: Cytokine)
Source: Cytokine - April 15, 2024 Category: Molecular Biology Authors: Deepak Berwal Dumitru D Branisteanu Mia Glickman Amit Sagar Julie G Pilitsis Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Expression and function of cytokine interleukin-22 gene in the tumor microenvironment of triple negative breast cancer
CONCLUSION: The findings suggested that targeting IL-22 and its related pathways can offer new insights for developing effective therapies for TNBC.PMID:38581864 | DOI:10.1016/j.cyto.2024.156590 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Yibin Xiao Xia Zhao Yihui Guo Yanping Li Source Type: research

Low expression of interleukin-1 receptor antagonist correlates with poor prognosis via promoting proliferation and migration and inhibiting apoptosis in oral squamous cell carcinoma
CONCLUSIONS: In summary, our investigation highlighted the possible involvement of low-expression IL1RA in OSCC cells in promoting invasive as well as metastatic and inhibiting apoptosis, as well as the efficacy of IL1RA-focused monitoring in the early detection and treatment of OSCC.PMID:38581865 | DOI:10.1016/j.cyto.2024.156595 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Yujie Ding Jie Yi Yufei Shan Jiaqi Gu Zhida Sun Jie Lin Source Type: research

Diagnostic, monitoring, and prognostic value of combined detection of cerebrospinal fluid heparin-binding protein, interleukin-6, interleukin-10, and procalcitonin for post-neurosurgical intracranial infection
CONCLUSION: The combined detection can be an important indicator for the diagnosis and disease monitoring of post-neurosurgical intracranial infection.PMID:38581866 | DOI:10.1016/j.cyto.2024.156593 (Source: Cytokine)
Source: Cytokine - April 6, 2024 Category: Molecular Biology Authors: Xinfang Pan Dina Haishaer Mei Liu Shaobo Zhou Heya Na Hongmei Zhao Source Type: research