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Nervenarzt. 2009 Nov 19; Authors: Strupp M, Katsarava Z The major invasive procedure of the neurologist is the spinal tap. Its most frequent complication is post-lumbar puncture syndrome/headache. The syndrome's leading symptom is posture-dependent headache, which is caused by the prolonged escape of CSF from a dural leak. Its frequency lies between 1 and 30%, depending on the technique used for lumbar puncture. An important measure for reducing the risk of its occurrence is the use of a small (22-gauge), atraumatic Sprotte or Whitacre needle. The treatment of choice for the syndrome is caffeine, and if ineffective...
Source: Der Nervenarzt - November 19, 2009 Category: Neurology Authors: Strupp M, Katsarava Z Tags: Nervenarzt Source Type: journals

[Prof. Dr. med. Franz Müller-Spahn : 18.08.1950 to 04.08.2009.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
[Prof. Dr. med. Franz Müller-Spahn : 18.08.1950 to 04.08.2009.] Nervenarzt. 2009 Nov 18; Authors: Dittmann V, Müller N, Möller HJ PMID: 19921502 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - November 18, 2009 Category: Neurology Authors: Dittmann V, Müller N, Möller HJ Tags: Nervenarzt Source Type: journals

[Epilepsy and driving : Background, new German guidelines and comments.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The German guidelines for driving licenses concerning people with epilepsy or those who experienced single epileptic seizures have been revised. In cases of epilepsy a seizure-free period of 12 months is required for group 1 drivers (e.g. passenger cars). A seizure-free period of 5 years without antiepileptic drugs is mandatory for group 2 drivers (e.g. trucks) with epilepsy. A seizure-free interval of 3 months (group 1) or 6 months (group 2) is required after a single epileptic seizure caused by a plausible provocative factor. The guidelines stress that people who experienced a seizure induced by sleep deprivation may...
Source: Der Nervenarzt - November 13, 2009 Category: Neurology Authors: Bauer J, Neumann M Tags: Nervenarzt Source Type: journals

[Antihistaminergic antipsychotics cause weight gain.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In recent years, weight gain has increasingly gained attention as a side effect of antipsychotic therapy due to its metabolic and cardiovascular health risks and its negative effect on therapy compliance. The various antipsychotics show clear differences concerning their influence on body weight. These differences seem to be mainly due to the affinity of these substances to the histaminergic H1 receptors and due to serotonergic mechanisms. In the hypothalamus, the antihistaminergic effect of those antipsychotics which are associated with a high amount of weight gain leads to an increase of the activity of the adenosine...
Source: Der Nervenarzt - November 11, 2009 Category: Neurology Authors: Veselinović T, Himmerich H Tags: Nervenarzt Source Type: journals

[Severe aseptic leucoencephalopathy : Manifested as immune reconstitution inflammatory syndrome in Caucasian and African patients.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Starting HAART, HIV-1-positive patients may develop an aseptic type of IRIS of the CNS without any detectable opportunistic infection, a finding that has not yet been published. This makes them susceptible for successful treatment with corticosteroids. Perhaps IRIS has a higher incidence in African patients and the patients have a poorer outcome than Caucasians. PMID: 19902166 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - November 11, 2009 Category: Neurology Authors: Ringelstein A, Oelschlaeger C, Arendt G, Mathys C, Dziewas R, Niederstadt T, Reichelt D, Hasselblatt M, Husstedt IW, Saleh A Tags: Nervenarzt Source Type: journals

[Aggressive immunotherapy in Susac's syndrome.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a previously healthy 36-year-old woman who presented with encephalopathy, central weakness of her right leg and multiple white matter lesions on MRI. Shortly thereafter, inner ear deafness developed and funduscopy revealed occlusions of branch retinal arteries. A diagnosis of retino-cochlear-cerebral vasculopathy or Susac's syndrome was established and steroid-based immunotherapy with high-dose corticosteroids was initiated. Steroid reduction led to repeated clinical worsening, so that immunotherapy was sequentially escalated. Finally, high-dose cyclophosphamide every 4 weeks led to sufficient control of disea...
Source: Der Nervenarzt - November 4, 2009 Category: Neurology Authors: Klein M, Illies T, Georgi S, Rosenkranz T, Terborg C Tags: Nervenarzt Source Type: journals

[Requirements and reality of the German Ordinance for Staff in Psychiatric Hospitals : Results of a multi-moment study on a psychiatric ward for acute psychosis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The PsychPV requirements must be urgently adapted so that more time is again available for the direct patient contact. PMID: 19876611 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - October 31, 2009 Category: Neurology Authors: Hoffmann M, Rieger W Tags: Nervenarzt Source Type: journals

[Conclusion: How should a meaningful meta-analysis of long-term psychodynamic psychotherapy be designed?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: How should a meaningful meta-analysis of long-term psychodynamic psychotherapy be designed?] Nervenarzt. 2009 Oct 28; Authors: Rief W, Hofmann SG In their answer to our critical evaluation of their meta-analysis about long-term psychodynamic psychotherapy (LTPP), Leichsenring and Rabung claim that all our critical points could be rejected. This is surprising, as the authors already confirmed different shortcomings of their analysis. Our major criticism is that the meta-analysis is based on very few high-quality studies (including follow-up assessments), but on many studies with poor quality and/or o...
Source: Der Nervenarzt - October 28, 2009 Category: Neurology Authors: Rief W, Hofmann SG Tags: Nervenarzt Source Type: journals

["Psychoanalysis should be rescued. : By all means?"]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19859682 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - October 28, 2009 Category: Neurology Authors: Dümpelmann M Tags: Nervenarzt Source Type: journals

[A favourite adversary: "classic long-term psychoanalysis" : Commentary on Rief and Hofmann's "Psychoanalysis should be rescued. By all means?"]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Rief and Hofmann (2009, Nervenarzt 80:593-597) harshly criticise the meta-analysis on the effectiveness of long-term psychodynamic psychotherapy (LTPP) by Leichsenring and Rabung (2008, JAMA 300(13):1551-1565). They find fault with the inclusion of naturalistic studies in addition to randomised clinical trials. Furthermore, they criticise the heterogeneity of the treatments included and the disorders studied. They suspect that a number of RCTs of LTPP with negative results for LTPP have been done and not been published. This paper comments on the following issues: the strict determination of RCTs is scientifically outd...
Source: Der Nervenarzt - October 28, 2009 Category: Neurology Authors: Benecke C, Boothe B, Frommer J, Huber D, Krause R, Staats H Tags: Nervenarzt Source Type: journals

[Core symptoms of depression.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19859684 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - October 28, 2009 Category: Neurology Tags: Nervenarzt Source Type: journals

[Personality in old age.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Modern developmental psychology tends to draw a positive, resource-based picture of human aging. We will however focus on more difficult aspects of personality in old age which are of psychiatric relevance: the persistence of cluster A and C personality disorders, antisocial personality in the elderly; the interaction of personality and a detection of mild cognitive impairment (MCI); personality features as risk or protective factors or early signs of Alzheimer's dementia; changes of personality in Parkinson's disease and frontotemporal dementia. We will briefly mention recent neuroimaging studies which appear to sugge...
Source: Der Nervenarzt - October 28, 2009 Category: Neurology Authors: Förstl H, Perneczky R, Karenberg A, Diehl-Schmid J, Lautenschlager NT Tags: Nervenarzt Source Type: journals

[Tics and Tourette's syndrome throughout the life span.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic motor and vocal tics lasting longer than a year are classified as Tourette's syndrome (TS). Tics mostly manifest before the age of 11 years. Boys are affected at a threefold higher rate than girls. Tics are often worst at the age of 14; in 50% of the cases the tic symptoms will remit nearly completely. Severely affected patients often suffer from comorbidities. In childhood and adolescence the most common comorbid condition is attention deficit hyperactivity disorder (ADHD). Obsessive-compulsive behaviour, anxiety and affective disorder might occur in the course of TS. A dysregulation in the dopaminergic neurot...
Source: Der Nervenarzt - October 25, 2009 Category: Neurology Authors: Neuner I, Ludolph A Tags: Nervenarzt Source Type: journals

[On the efficacy of long-term psychodynamic psychotherapy for complex psychological disorders.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Rief and Hofmann (Nervenarzt 80:593-597) criticize in a very detailed comment our meta-analysis of long-term psychodynamic psychotherapy (JAMA 300:1551-1565). Although our article clearly included information that our meta-analysis addressed long-term psychodynamic psychotherapy of at least 50 sessions or at least 1 year duration, Rief and Hofmann allege that we studied "psychoanalysis" or "long-term psychoanalysis". Then they "show" for some of the studies we included that these studies did not address "psychoanalysis" or "long-term psychoanalysis" - which they did indeed not, but had never been claimed by us. For all...
Source: Der Nervenarzt - October 24, 2009 Category: Neurology Authors: Leichsenring F, Rabung S Tags: Nervenarzt Source Type: journals

[Psychiatry over the course of life.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19851744 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - October 24, 2009 Category: Neurology Authors: Schneider F, Maier W Tags: Nervenarzt Source Type: journals

[Options, limits and ethics of pharmacological neuroenhancement.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pharmacological neuroenhancement is an attempt to increase cognitive performance in healthy humans. Learning and memory, attention and vigilance or mood and social interaction are targeted by a modulation of brain plasticity. Firstly, an analysis of the current state of research shows that, until now, clinical trials of neuroenhancing drugs have demonstrated only limited efficacy and long-term side effects remain largely unexplored. Secondly, we argue that, from an ethical perspective, neuroenhancement differs from socially mediated methods of learning. Pharmacological neuroenhancement is based on notions of efficacy a...
Source: Der Nervenarzt - October 24, 2009 Category: Neurology Authors: Normann C, Boldt J, Maio G, Berger M Tags: Nervenarzt Source Type: journals

[Wilson's disease and multiple sclerosis :]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a 38-year-old male patient who was diagnosed with a hepatic form of Wilson's disease at age 12 and with multiple sclerosis at age 38. Intravenous radio copper test confirmed the diagnosis of Wilson's disease. Multiple sclerosis was diagnosed after occurrence of transient sensory disturbances in both legs, based on typical changes on MRI over the course of 2 years, in the cerebrospinal fluid and in multimodal evoked potentials.Although Wilson's disease and multiple sclerosis are known as distinct diseases with a completely different pathophysiology, symptoms and results of evoked potentials overlap, and they sh...
Source: Der Nervenarzt - October 23, 2009 Category: Neurology Authors: Günther P, Baum P, Then Bergh F, Hermann W Tags: Nervenarzt Source Type: journals

[Psychological factors related to gastric banding : Results of a follow-up study.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This study pointed out the necessity for psychotherapeutic help after surgery to manage already existing or new psychological needs due to gastric banding. PMID: 19838661 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - October 16, 2009 Category: Neurology Authors: Bölter AF, Rosenthal A, Wolff S, Franke GH, Frommer J Tags: Nervenarzt Source Type: journals

[Vaccination and multiple sclerosis.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vaccinations to prevent communicable diseases are, like in other chronic diseases, of special importance in patients with multiple sclerosis (MS). Various bacterial and viral infections have been shown to induce relapses of MS. Reports of possible adverse effects of vaccinations on the course of multiple sclerosis have led patients and treating physicians to exercise caution in the use of vaccines. A number of vaccines have been studied with respect to the risk in MS patients. Some vaccines, for example against yellow fever, are not indicated in MS due to the risk of MS exacerbation. In contrast, tetanus or hepatitis B...
Source: Der Nervenarzt - October 16, 2009 Category: Neurology Authors: Löbermann M, Winkelmann A, Reisinger EC, Zettl UK Tags: Nervenarzt Source Type: journals

[Addiction across the lifespan.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Alcohol and nicotine are with us during most of our lifetime. About 4,000 children with fetal alcohol syndrome and another 20,000 children with fetal alcohol effects are born per year in Germany. Alcohol contributes to accidents and suicides especially in young people. It is particularly toxic for the developing brain.Germany is among the countries with a high consumption of alcohol and nicotine. Consequently substance-related diseases are highly prevalent. In the group of people aged 65 and older we expect a doubling of alcohol problems within the next 10 years. This will also lead to a sharp increase in alcohol-relat...
Source: Der Nervenarzt - October 16, 2009 Category: Neurology Authors: Mann K, Laucht M, Weyerer S Tags: Nervenarzt Source Type: journals

[Equal access to medical services over the lifespan.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Demand for health services is in principle unlimited, in contrast to resources. People covered by public health funds in principle have equal access to treatment according to the highest level of medical evidence available. In order to restrict expenditure the legislator stipulates different instruments. These include reference pricing for generics as well as price capping. The legislator still shies from price fixing which is well established in other states. Instead, office-based physicians are confronted by law with rationing decisions concerning their own services as well as services prescribed where the mentally i...
Source: Der Nervenarzt - October 16, 2009 Category: Neurology Authors: Fritze J Tags: Nervenarzt Source Type: journals

[In Process Citation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19830471 [PubMed - in process] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 30, 2009 Category: Neurology Tags: Nervenarzt Source Type: journals

[In Process Citation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19830472 [PubMed - in process] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 30, 2009 Category: Neurology Tags: Nervenarzt Source Type: journals

[In Process Citation]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19830473 [PubMed - in process] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 30, 2009 Category: Neurology Tags: Nervenarzt Source Type: journals

[Patients of immigrant origin in inpatient psychiatric facilities : Differences between first and second generation: nationwide questionnaire of the Psychiatry and Migration Working Group of the German Federal Conference of Psychiatric Hospital Directors.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In a representative nationwide survey, the Psychiatry and Migration Working Group of the German Federal Conference of Psychiatric Hospital Directors examined the use of inpatient psychiatric and psychotherapeutic services in Germany by patients of immigrant origin. Questionnaires were sent to a total of 350 general hospital psychiatric clinics throughout Germany and 131 responded by the specified deadline (19 July 2006).In our study, persons of immigrant origin comprised 17% of patients in the responding facilities, which confirmed the results of the pilot study in 2004 of 17.4%. This indicates that the percentage of i...
Source: Der Nervenarzt - September 26, 2009 Category: Neurology Authors: Schouler-Ocak M, Schepker R, Bretz HJ, Hartkamp N, Koch E, Penka S, Hauth I, Rapp MA, Aichberger MC, Heinz A Tags: Nervenarzt Source Type: journals

[Atacicept: a new B lymphocyte-targeted therapy for multiple sclerosis :]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Multiple sclerosis (MS) has traditionally been considered to be a T cell-mediated disease. However, there is an increasing body of evidence for the involvement of B cells and autoantibodies in the pathology of this disease, providing a rationale for treatment strategies directed against B cells. This paper summarizes the evidence for a key role of B cells in the immunopathology of MS and reviews data supporting the use of a novel B cell-targeted therapy, atacicept, for this condition. Atacicept is a human recombinant fusion protein that comprises the binding portion of a receptor for both BLyS (B Lymphocyte Stimulator)...
Source: Der Nervenarzt - September 25, 2009 Category: Neurology Authors: Hartung HP Tags: Nervenarzt Source Type: journals

[Bilateral spontaneous carotid artery dissection in osteogenesis imperfecta (type I).]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a 36-year-old patient with an acute cerebral infarction due to a spontaneous dissection of both internal carotid arteries in conjunction with type I osteogenesis imperfecta. Spontaneous dissections of cerebral arteries (DCA) represent a common cause of cerebral infarctions in younger patients. Our case shows that a hereditary connective tissue disorder should be considered in all patients with "spontaneous" DCA. The identification of an - initially unknown - hereditary connective tissue disorder may contribute to primary and secondary prophylaxis of cerebral ischemia. PMID: 19768444 [PubMed - as supplied b...
Source: Der Nervenarzt - September 19, 2009 Category: Neurology Authors: Becker C, Roth C, Reith W, Fassbender K, Spiegel J Tags: Nervenarzt Source Type: journals

[Gottfried Benn and schizoidism.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Based on increasing criticism concerning operational diagnostics in psychiatry, the concept of schizoid personality disorder in ICD and DSM is discussed critically. In a case study regarding the poet and doctor Gottfried Benn, the limitation of manualized, context-independent diagnostic systems is shown. In contrast Ernst Kretschmer's concept of schizoidism seems suitable to describe a schizoid character in his ambiguity. PMID: 19768445 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 19, 2009 Category: Neurology Authors: Pliska G Tags: Nervenarzt Source Type: journals

[Measurement of publication performance.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19768446 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 19, 2009 Category: Neurology Authors: Hacke W, Diener HC, Hartung HP, Elger C, Brandt TH Tags: Nervenarzt Source Type: journals

[Attention deficit hyperactivity syndrome throughout the life span.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Attention deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders in children. ADHD is often chronic persisting into adulthood in about 60% of patients. The disorder is frequently associated with co-occurring disruptive, anxiety, mood and personality disorders as well as substance abuse. The diagnosis of ADHD has to be based on careful assessment of symptoms and impairments in the different phases of life. Recent neuroimaging and genetic data support the neurobiological basis of the disorder. Multimodal treatment options including stimulants, antidepressants and behavioral therapy pla...
Source: Der Nervenarzt - September 19, 2009 Category: Neurology Authors: Konrad K, Rösler M Tags: Nervenarzt Source Type: journals

[Personality disorders in childhood and adolescence.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The diagnosis of a personality disorder is defined by the fact that personality traits are formed by early childhood, but German clinicians very rarely diagnose children and adolescents with personality disorders. Opponents of diagnosing personality disorders in childhood want to avoid labeling and refer to the developmental aspect of the personality. Supporters argue that children and adolescents already possess a describable personality and the developmental process continues into adulthood. By recognizing the pathological personality tendencies early enough allows an early therapy which can prevent an acute progress...
Source: Der Nervenarzt - September 19, 2009 Category: Neurology Authors: Jucksch V, Salbach-Andrae H, Lehmkuhl U Tags: Nervenarzt Source Type: journals

[Car driving ability of patients with frontotemporal lobar degeneration and Alzheimer's disease.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Patients with FTLD should cease driving as soon as possible in the course of the disease. With patients suffering from mild AD an individual assessment should be made. PMID: 19763528 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 18, 2009 Category: Neurology Authors: Ernst J, Krapp S, Schuster T, Förstl H, Kurz A, Diehl-Schmid J Tags: Nervenarzt Source Type: journals

[Fragile X-associated tremor/ataxia syndrome.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a recently characterized adult onset neurodegenerative disorder affecting both male and female (male>female) carriers of premutation CGG repeat expansions of the FMR1 gene. Onset typically occurs after the age of 50 years with a lifetime risk of FXTAS in males of about 1 in 3,000-6,000. Core features include progressive gait ataxia and cerebellar tremor with associated features of cognitive deficits, peripheral neuropathy and dysautonomia. The diagnosis of FXTAS is established based on clinical presentation, cerebral imaging and genetic testing. Due to the still...
Source: Der Nervenarzt - September 18, 2009 Category: Neurology Authors: Finke C, Horváth R, Holinski-Feder E, Ploner CJ Tags: Nervenarzt Source Type: journals

[Repetitive peripheral magnetic stimulation : Treatment option for spasticity?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The RPMS could prove to be an effective option for the treatment of spasticity. However, this method needs further evaluation by evidence-based studies. PMID: 19763530 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 18, 2009 Category: Neurology Authors: Marz-Loose H, Siemes H Tags: Nervenarzt Source Type: journals

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Nervenarzt. 2009 Sep 2; Authors: Volz HP, Reischies F, Riedel M Cognitive disorders have become a major topic not only in the scientific community but also among clinicians. Cognitive disorders are of special importance in schizophrenic patients. The present paper gives a survey over the basic definitions and the extent of these disturbances in schizophrenic patients, the main etiopathogenetic hypotheses and the development over time as well as treatment options with special regard to psychopharmacological treatment options. PMID: 19727640 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - September 1, 2009 Category: Neurology Authors: Volz HP, Reischies F, Riedel M Tags: Nervenarzt Source Type: journals

[Refuting the "myth of self-infliction" : Addiction psychiatry 2009.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19711049 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 27, 2009 Category: Neurology Authors: Mann K, Kiefer F Tags: Nervenarzt Source Type: journals

[Cortical venous thrombosis after a diagnostic lumbar puncture.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the case of a 49-year-old female patient who underwent a lumbar puncture in the context of an extended diagnostic work-up after a transient ischemic attack. A few days later the patient who suffered from severe post-lumbar puncture headache, developed a lobar hemorrhage due to a cortical venous thrombosis requiring decompression surgery. PMID: 19707734 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 26, 2009 Category: Neurology Authors: Pfeilschifter W, Neumann-Haefelin T, Hattingen E, Singer OC Tags: Nervenarzt Source Type: journals

[Depression during pregnancy and its treatment.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Approximately 11% of pregnant women suffer from major depression which requires treatment and if left untreated there are risks of preterm delivery or low birth weight. The initial difficulty lies in diagnosing the depression itself, as many symptoms of depression can be ascribed to the pregnancy. A further challenge is choosing the appropriate therapy. Treatment options are psychotherapy, antidepressants, electroconvulsive therapy (ECT) or the new possibility of light therapy. A growing number of reports on the side effects of antidepressants in pregnancy have led to uncertainties as to how to proceed. Thus, choosing ...
Source: Der Nervenarzt - August 26, 2009 Category: Neurology Authors: Bader A, Frisch U, Wirz-Justice A, Riecher-Rössler A Tags: Nervenarzt Source Type: journals

[Sexual dysfunction in remittent depressive women.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Impaired sexual function is a common feature in depressive disorders. In some cases sexual problems even persist after remission and the observed sexual dysfunctions negatively affect quality of life. A detailed patient history is important to detect sexual problems. PMID: 19707736 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 26, 2009 Category: Neurology Authors: Baranyi A, Stepan A, Rothenhäusler HB Tags: Nervenarzt Source Type: journals

[Social cognition in schizophrenia : Mentalising and psychosocial functioning.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews the evidence for such an association. Findings imply the integration of social-cognitive training in a treatment concept for schizophrenia. However, to date it remains elusive whether or not the impact of improved social cognition on psychosocial functioning is stable over prolonged periods of time. To answer this open question requires longitudinal studies that are currently unavailable. PMID: 19705091 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 25, 2009 Category: Neurology Authors: Brüne M, Juckel G Tags: Nervenarzt Source Type: journals

[Chronic progressive aphasia.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Progressive aphasia (PA) caused by neurodegenerative diseases is much less prevalent than aphasia following vascular brain lesions. Clinically, the progressive aphasias can be divided in progressive non-fluent aphasia, semantic dementia and logopenic aphasia. Differential diagnosis is based on a detailed language assessment and neuroimaging. Compared with the therapy of aphasia following stroke the treatment of patients with PA has been neglected. However, recently potential therapeutic options have been evaluated regarding feasibility and efficacy. PMID: 19705092 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 25, 2009 Category: Neurology Authors: Diehl-Schmid J, Knels C, Danek A Tags: Nervenarzt Source Type: journals

[Extended suicide : A problematic term.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In German psychiatry the concepts of homicide/suicide, collective suicide and double suicide are not precisely defined. These acts should be described formally as homicide with subsequent suicide or as homicide with subsequent suicide attempts. The psychopathological symptoms alone are important for the expertise but not a possible psychodynamic interpretation. PMID: 19701619 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 22, 2009 Category: Neurology Authors: Foerster K Tags: Nervenarzt Source Type: journals

[On the hermeneutics of depressive despair.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despair refers to a psychopathological phenomenon which is difficult to grasp. Its formal structure (Formalanzeige) has previously been described in a publication. The formal structure serves in the following as the basis for a hermeneutic examination of depression. Depressive despair is a development which originates from an antagonism within the biographically evolved personality. This antagonism increasingly tears apart aspects of reality and aspects of desire, begins to oscillate in the form of dichotomies and, in the worst case, leads to hopelessness and suicide. In favourable cases, this process can result in a r...
Source: Der Nervenarzt - August 22, 2009 Category: Neurology Authors: Bürgy M Tags: Nervenarzt Source Type: journals

[Gambling and internet addiction : Review and research agenda.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Behavioral addictions, especially pathological gambling and internet addiction, have become a growing concern in research and health policy. Similarities between behavioral addictions and substance dependency are currently being discussed in the scientific community. Unfortunately the number of scientific studies on pathological gambling and internet addiction is still very low. The estimated prevalence of pathological gambling among the German population is 0.2-0.5%. These numbers are comparable to prevalence rates reported for illegal drug dependency. About 1.5 million people, i.e. 3% of the German population, are be...
Source: Der Nervenarzt - August 21, 2009 Category: Neurology Authors: Wölfling K, Bühler M, Leménager T, Mörsen C, Mann K Tags: Nervenarzt Source Type: journals

[SSRI - treatment and bleeding : What risks do we take?]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Treatment with selective serotonin reuptake inhibitors (SSRI) increases the risk of gastrointestinal bleeding. The combination with non-steroidal anti-inflammatory drugs (NSAIDs) further augments this hazard. Particular precaution is also necessary in patients on platelet aggregation inhibitors, with a known bleeding disorder or preceding gastrointestinal lesions. The incidence of bleeding events apart from the gastrointestinal tract, e.g. intracerebral hemorrhages, is not cumulated under SSRI treatment. This also applies for the combination of SSRI and coumarin or aspirin. Prescribing doctors have to be aware of the b...
Source: Der Nervenarzt - August 20, 2009 Category: Neurology Authors: Strubel T, Birkhofer A, Mößmer G, Förstl H Tags: Nervenarzt Source Type: journals

[Functional nuclear magnetic resonance tomography in patients with schizophrenia : Neural correlates of symptoms, cognition and emotion.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In patients with schizophrenia, numerous mental processes are impaired, which can be related to brain systems using functional imaging methods (e.g. functional magnetic resonance imaging; fMRI). In this review the methodological and conceptual background of fMRI will first be discussed. Secondly, the cerebral networks involved in important symptoms of schizophrenia such as hallucinations, delusions and formal thought disorders will be outlined. Furthermore, the pathways of the central nervous system involved in cognitive dysfunction in patients with schizophrenia will be described also in the dependence on genotype and...
Source: Der Nervenarzt - August 20, 2009 Category: Neurology Authors: Kircher T, Leube D, Habel U Tags: Nervenarzt Source Type: journals

[Treatment of tobacco dependence : A responsibility of psychiatry and addiction medicine.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The World Health Organisation (WHO) considers smoking to be the biggest avoidable health risk. The consumption of tobacco leads to health hazards and resulting diseases, the consequences of which are far more serious than those emanating from other addictive substances. Approximately 27% of the German adult population smoke regularly and the proportion of smokers addicted to tobacco or nicotine is estimated to be around 60%. Many of these smokers have undertaken numerous unsuccessful attempts at abstinence. A professional support for smokers who are motivated to give up smoking enhances the chances of success. The curr...
Source: Der Nervenarzt - August 20, 2009 Category: Neurology Authors: Batra A, Friederich HM, Lutz U Tags: Nervenarzt Source Type: journals

[Evidence-based psychotherapy : Addiction and personality disorders as comorbidities.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article summarizes the current state of knowledge and introduces both methods by highlighting the core therapeutic strategies. PMID: 19690826 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 19, 2009 Category: Neurology Authors: Kienast T, Roediger E, Kensche M, Foerster J, Daig I, Heinz A Tags: Nervenarzt Source Type: journals

[EYEMOVE : Standardized assessment and treatment of visual search disorders.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Disorders of visual search by coordinated eye and head movements are frequently encountered in patients with brain damage. Homonymous visual field disorders, impaired elementary visual capacities (e.g. acuity, contrast sensitivity, convergent fusion, oculomotor disorders), visual neglect, Balint-Holmes syndrome or dementia (e.g. Alzheimer's disease) are the most frequent causes of such disorders. Efficient visual search is necessary to select salient stimuli and bring them onto the fovea in order to perform an in-depth analysis. Visual search is not only an indispensible capacity for visual activities in vocational and...
Source: Der Nervenarzt - August 12, 2009 Category: Neurology Authors: Kerkhoff G, Marquardt C Tags: Nervenarzt Source Type: journals

[Comorbidity of substance use disorders and attention-deficit hyperactivity disorders : Pathogenesis and therapy.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Substance use disorders (e.g. substance addiction, substance abuse) and adult attention-deficit hyperactivity disorders (adult ADHD) are frequent psychiatric disorders with a high individual and social relevance. Complex interactions of common and divergent susceptibility genes and environmental factors are important for both disorders which have a relatively high heritability. Substance use disorders and adult ADHD are both associated with an increased risk for additional axis I disorders. The results of studies with respect to the comorbidity of adult ADHD and substance use disorders are inconsistent. Different hypot...
Source: Der Nervenarzt - August 12, 2009 Category: Neurology Authors: Fallgatter AJ, Jacob CP Tags: Nervenarzt Source Type: journals