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664 records returned

Satisfying patient expectations with soft-tissue augmentation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article suggests a series of steps to help determine the most appropriate approach for volume restoration with injectable devices for satisfying patient treatment expectations. PMID: 19903429 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Mandy SH Tags: Dermatol Online J Source Type: journals

Nail disease in pemphigus vulgaris.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients affected by pemphigus vulgaris will occasionally present with associated and characteristic nail changes. This manuscript was prepared as a review of this unique presentation of pemphigus. Articles describing pemphigus vulgaris of the nail were compiled and reviewed and pertinent information was extracted to provide a concise analysis. The literature on this topic is still maturing. Publications to date suggest the incidence of nail and periungal involvement may correlate with the severity of mucocutaneous symptoms and the duration of the disease. The most common nail manifestations reported were acute or chro...
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Serratos BD, Rashid RM Tags: Dermatol Online J Source Type: journals

Pioderma gangrenoso - Abordagem clínica, laboratorial e terapêutica: Revisão de 28 casos.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a retrospective study of 28 patients, admitted to Hospital de São João, EPE, between January of 1990 and June of 2008. Pyoderma gangrenosum was observed more frequently in middle age adults, in the ulcerated form, and predominantly localized in the lower limbs. Pediatric presentation was very rare. In 50 percent of these cases a systemic disease was present and the most frequent was Crohn disease (14% of patients). PMID: 19903431 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Duarte AF, Nogueira A, Lisboa C, Azevedo F Tags: Dermatol Online J Source Type: journals

Advice for medical students interested in dermatology: Perspectives from fourth year students who matched.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present perspectives from four fourth year medical students who matched into dermatology that highlight the factors they believed helped them most. The purpose is to offer advice to medical students interested in dermatology. We divide the paper into four areas of discussion: academics, extracurricular activities, research, and mentorship. All four factors are crucial for a strong dermatology application. We believe the paper provides valuable suggestions and guidance to students considering a career in dermatology. PMID: 19903432 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Alikhan A, Sivamani RK, Mutizwa MM, Aldabagh B Tags: Dermatol Online J Source Type: journals

A case of bullous disease limited to the skin illustrates the spectrum of neoplasia induced autoimmunity.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a patient with fatal autoimmune blistering disease with absence of mucous membrane lesions. The pattern of complement indirect immunofluoresence helped identify the prognosis prospectively. This case illustrates yet another presentation of the neoplasia-induced autoimmunity. PMID: 19903433 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Grover RK, Stites PC, Helm TN, Hashimoto T, Beutner EH Tags: Dermatol Online J Source Type: journals

A case of primary cutaneous B cell lymphoma of the knee.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a gentleman with a primary cutaneous B cell lymphoma of the leg who underwent an amputation and later died. This is an uncommon type of cutaneous lymphoma with poor prognosis and the case demonstrates how aggressive the tumor can become. PMID: 19903434 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Turner EJ, Tsim H, Pawade J, Wolowczyk L Tags: Dermatol Online J Source Type: journals

Pseudoxanthoma elasticum-like syndrome and thalassemia: An update.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe three cases of the acquired PXE-like syndrome that often occurs in association with hemolytic anemias, in particular the hemoglobinopathies, and review the literature on the subject. The pathogenesis of the acquired PXE-like lesions is not yet completely understood. None of the mutations observed in the inherited form has been detected in the syndrome accompanying thalassemia. The cardiovascular complications could be life-threatening. Therefore, an close surveillance of these patients is mandatory. PMID: 19903435 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Fabbri E, Forni GL, Guerrini G, Borgna-Pignatti C Tags: Dermatol Online J Source Type: journals

Mucoceles not - Oral cysticercosis and minor salivary gland adenocarcinoma: Two case reports.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present two cases that were clinically diagnosed as mucoceles that were removed because of patient anxiety. However, histological examination revealed dissimilar and medically significant pathologies. Oral cysticercosis and salivary gland adenocarcinoma are rare diseases of the oral mucosa. It is important to consider these and other uncommon diagnoses when evaluating an oral nodule presumed to be a mucocele. We will discuss the natural history and pathogenesis of these disease processes. PMID: 19903436 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Lee KH, Cepeda L, Miller M, Siegel DM Tags: Dermatol Online J Source Type: journals

Keratoacanthoma in a tattoo.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a keratoacanthoma arising in a recent tattoo. A 60-year-old woman presented with a tumor on her right leg, over an area of red pigment in a professional tattoo. Histological analysis confirmed the clinical diagnosis of keratoacanthoma. Although the association between malignancy and tattoos is very uncommon dermatologists and dermatologic surgeons should be attentive to this possibility. PMID: 19903437 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Gon AS, Minelli L, Meissner MG Tags: Dermatol Online J Source Type: journals

A remarkable case of cutaneous metastatic breast carcinoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a 50-year-old woman with a 5-month history of multiple asymptomatic papulonodular lesions on the left chest area. Biopsy was consistent with cutaneous metastases from a ductal breast carcinoma. No distant metastatic lesions were detected. The patient was referred to the Gynecologic Oncology Department. Treatment included chemotherapy, radiotherapy and surgery. At present the patient is well with no signs of recurrence. This case reports a clinically remarkable cutaneous metastatic breast carcinoma. PMID: 19903438 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Santiago F, Saleiro S, Brites MM, Frutuoso C, Figueiredo A Tags: Dermatol Online J Source Type: journals

Title.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
TITLE. Dermatol Online J. 2009;15(7):11 Authors: Last FM, Last FM, Last FM ABSTRACT. PMID: 19903439 [PubMed - as supplied by publisher] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Last FM, Last FM, Last FM Tags: Dermatol Online J Source Type: journals

Autologous "foreign body" as a sequel of improper cutting of an ingrowing toe nail?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on a 63-year-old male who suffered from an ingrown toenail affecting the left first digit for several years. Medical history revealed that repeated vigorous nail plate trimming by the patient relieve the red, painful swelling of his great toe. Furthermore, Emmert onychoplasty as well as non-invasive procedures did not achieve improvement. A thorough surgical exploration of the affected area detected a nail spicule in the deeper paronychium. This was likely caused by improper cutting of the nail plate. Removal of the fragment in combination with partial nail plate excision, followed by phenol cauterization of the ...
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Jessberger B, Ring J, Möhrenschlager M Tags: Dermatol Online J Source Type: journals

Saphenous vein harvesting site dermatoses in eastern India.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the cutaneous effects at the saphenous vein harvesting sites in 21 patients who underwent CABG. PMID: 19903441 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Ghosh SK, Bandyopadhyay D Tags: Dermatol Online J Source Type: journals

Drug-induced pruritic micropapular eruption: anastrozole, a commonly used aromatase inhibitor.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anastrozole, a selective nonsteroidal aromatase inhibitor is widely used as an adjuvant therapy for postmenopausal women with early hormone-sensitive breast cancer. There are few reports on cutaneous side effects of anastrozole. It may induce subacute cutaneous lupus erythematosus, erythema nodosum, cutaneous vasculitis, and nondescript skin eruptions. A 68-year-old woman was prescribed anastrozole after surgical removal of her breast cancer and adjuvant radiation therapy. Two months later she experienced a generalized pruritic micropapular eruption. History, clinical presentation, histology and inadvertent re-exposure...
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Bremec T, Demsar J, Luzar B, Pavlović MD Tags: Dermatol Online J Source Type: journals

Adalimumab in the management of palmoplantar psoriasis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Palmoplantar pustular psoriasis (PPP) is an uncommon form of chronic psoriasis. Characterized by sterile, intraepidermal pustules located on the palms and soles, it is highly resistant to treatment. Our patient presented with palmar inflammation and throbbing joint pain in his hands, as well as erythematous, pustular, and micaceous scaling skin on his right foot, legs, elbows, and hands. Approximately 4 percent of his body surface area was involved and he was diagnosed with PPP after skin biopsy. After conventional therapy failed, the patient underwent treatment with adalimumab and the majority of his symptoms resolved...
Source: Dermatol Online J - November 13, 2009 Category: Dermatology Authors: Ghate JV, Alspaugh CD Tags: Dermatol Online J Source Type: journals

Rowell syndrome (systemic lupus erythematosus + erythema multiforme).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 61-year-old woman with a history of chilblains and systemic lupus erythematosus (SLE) for 15 years presented with annular, erythematous, scaly papules and plaques on her face, neck, chest, abdomen, back, arms, and legs. A biopsy specimen showed a destructive interface dermatitis with extensive epithelial cell necrosis, which was consistent with lupus erythematosus with combined subacute cutaneous lupus and erythema multiforme-like features. These findings are most compatible with a diagnosis of Rowell syndrome. Rowell syndrome and its relation to lupus erythematosus and erythema multiforme are discussed. PMID: 19...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Lee A, Batra P, Furer V, Cheung W, Wang N, Franks A Tags: Dermatol Online J Source Type: journals

Eosinophilic fasciitis/generalized morphea overlap.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 50-year-old woman presented with a three-month history of violaceous, non-tender, indurated plaques on the chest, abdomen, breasts, and proximal portions of the arms and legs. An incisional biopsy specimen showed changes consistent with a diagnosis of inflammatory morphea. Over the course of one year, the patient began to develop signs and symptoms suggestive of a diagnosis of eosinophilic fasciitis, which included the characteristic groove sign on the upper extremities. Although our patient did not exhibit peripheral or histopathologic evidence of eosinophilia, the diagnosis of eosinophilic fasciitis could still be ...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Heidary N, Cheung W, Wang N, Kamino H, Franks AG Tags: Dermatol Online J Source Type: journals

Systemic drug-related intertriginous and flexural exanthema (SDRIFE).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 72-year-old man with a history of metastatic melanoma presented with a two-day history of erythematous and edematous plaques, with scattered bullae on the neck, chest, axillae, and inguinal and gluteal folds, which began five days after infusion of an experimental drug. The clinical and histopathologic findings were consistent with systemic drug-related intertriginous and flexural exanthema (SDRIFE), which is an uncommon drug reaction that results in symmetric erythema that affects the buttocks, groin, and/or thighs as well other flexural folds. The clinical manifestations of SDRIFE are highly characteristic and incl...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Elmariah SB, Cheung W, Wang N, Kamino H, Pomeranz MK Tags: Dermatol Online J Source Type: journals

Linear psoriasis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 33-year-old man presented with verrucous, red-brown papules, which coalesced into linear plaques on the right buttock, waist, thigh, and genitals. A skin biopsy was consistent with psoriasis, and the unilateral distribution in a linear pattern led to a diagnosis of linear psoriasis, which is a rare variant of psoriasis. Although histopathologically it can be difficult to distinguish from inflammatory linear verrucous epidermal nevus (ILVEN), linear psoriasis presents in adulthood and responds to conventional topical antipsoriatic therapies. PMID: 19891912 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Chien P, Rosenman K, Cheung W, Wang N, Sanchez M Tags: Dermatol Online J Source Type: journals

Fixed cutaneous sporotrichosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a patient with fixed cutaneous sporotrichosis whose delayed diagnosis led to appreciable scars and morbidity. PMID: 19891913 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Mahlberg MJ, Patel R, Rosenman K, Cheung W, Wang N, Sanchez M Tags: Dermatol Online J Source Type: journals

Generalized eruptive keratoacanthomas of Grzybowski.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 48-year-old man presented with a two-year history of a generalized, pruritic eruption that was associated with numerous, dome-shaped papules and nodulocystic lesions. Biopsy specimens have shown keratoacanthomas and a lichenoid dermatitis. Evaluation for malignant conditions has been negative. Owing to the constellation of findings, a diagnosis of generalized eruptive keratoacanthomas of Grzybowski associated with lichenoid dermatitis and acneiform lesions is favored. The patient is currently on a trial of acitretin. PMID: 19891914 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Lu PD, Lee A, Cassetty CT, Cheung W, Wang N, Halpern AC, Cohen DE Tags: Dermatol Online J Source Type: journals

Lymphedema praecox.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 57-year-old man presented with the post-pubertal onset of asymptomatic swelling of the left arm and legs that had been complicated by recurrent bouts of cellulitis. The presentation and disease course are consistent with lymphedema praecox, which is a subtype of primary lymphedema with onset at puberty and a slowly progressive course. The subtypes of lymphedema, pathogenesis, and treatment are reviewed. PMID: 19891915 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Rizzo C, Gruson LM, Wainwright BD Tags: Dermatol Online J Source Type: journals

Porokeratosis palmaris et plantaris disseminata or a disseminated late-onset variant of porokeratotic eccrine ostial and dermal ductal nevus (PEODDN) with follicular involvement.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 48-year-old woman presented with a four-year history of pruritic, hyperkeratotic, spiny papules that began on her chest and spread to her extremities, groin, palms, face, and scalp where it caused non-scarring alopecia. Histopathologic features included cornoid lamella, which is the hallmark of porokeratosis. However, the patient's constellation of findings does not meet diagnostic criteria for any of the five clinical variants of porokeratosis. Her presentation is most compatible with either porokeratosis palmaris et plantaris disseminata (PPPD), which is a rare variant of punctate porokeratosis that can involve any...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Hartman R, Rizzo C, Patel R, Kamino H, Shupack JL Tags: Dermatol Online J Source Type: journals

POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 62-year-old woman with hypothyroidism presented with a seven-year history of paresthesias, itching, and edema of the skin. Physical examination showed indurated, edematous plaques on the lower extremities. A biopsy specimen showed increased mucin deposition that was consistent with myxedema, and monoclonal IgM was observed on immunofixation. The constellation of findings, which included paresthesias, endocrinopathy, monoclonal gammopathy, and skin changes was consistent with POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome, which is a rare multisystemic disease th...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Liang C, Gonzalez M, Patel R, Meehan S, Kamino H, Franks AG Tags: Dermatol Online J Source Type: journals

Cutaneous piloleiomyomata.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 49-year-old man presented with an eight-month history of intermittently painful, subcutaneous nodules that were increasing in size, number, and pain intensity. A biopsy specimen showed smooth muscle proliferation, which also stained positive for actin, and was consistent with piloleiomyoma. The patient was placed initially on gabapentin and then nifedipine with very limited success in pain control. The lesions continued to proliferate, and the patient was referred to surgery for excision. PMID: 19891918 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Smith G, Heidary N, Patel R, Rosenman K, Meehan SA, Kamino H, Sanchez M Tags: Dermatol Online J Source Type: journals

Keratitis-ichthyosis-deafness (KID) syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report draws attention to inflammatory nodules (representing ruptured folliculitis), cysts, and recurrent infections on the scalp as manifestations of KID syndrome and reviews the increasingly recognized risk of follicular tumors and squamous-cell carcinomas in patients with this conditions. PMID: 19891919 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Gonzalez ME, Tlougan BE, Price HN, Patel R, Kamino H, Schaffer JV Tags: Dermatol Online J Source Type: journals

Acquired smooth-muscle hamartoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 52-year-old woman presented with an occasionally pruritic, hyperpigmented and hypertrichotic, indurated plaque on the left upper arm that initially developed during childhood. Histopathologic examination showed changes that were consistent with a smooth-muscle hamartoma. Cutaneous smooth-muscle hamartomas are uncommon benign neoplasms. Most lesions are congenital, but there have been a few reports of acquired lesions. These lesions have been described as part of a spectrum of neoplasms that include Becker nevi since they share many clinical and histopathologic features. PMID: 19891920 [PubMed - in process] (Sourc...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Yancovitz M, Gonzalez ME, Votava HJ, Walters R, Kundu R, Shupack JL Tags: Dermatol Online J Source Type: journals

Lichenoid drug eruption.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 78-year-old man presented with an eight-month history of folliculocentric, pink, hyperkeratotic papules and plaques with thick white scale that involved the entire body, with confluence on the buttocks and genitalia. A biopsy specimen demonstrated superficial and focal, mild perivascular and perifollicular, band-like lymphocytic infiltrate and eosinophils. There were lymphocytes extending to the dermo-epidermal junction with vacuolar changes. A diagnosis of lichenoid drug eruption secondary to a proton-pump inhibitor was made. To the best of our knowledge, only one other case of lichenoid drug eruption secondary to a...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Brauer J, Votava HJ, Meehan S, Soter NA Tags: Dermatol Online J Source Type: journals

Pityriasis rotunda.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 42-year-old man presented with asymptomatic, sharply-demarcated, round, scaly lesions on his forearms that had been present for several months. A skin biopsy specimen was consistent with pityriasis rotunda. Pityriasis rotunda is a disorder of keratinization, which is thought to be a form of acquired ichthyosis, a delayed presentation of congenital ichthyosis, or a cutaneous manifestation of systemic disease. Patients with pityriasis rotunda may be classified into one of two groups, which are based on ethnicity, number of lesions, family history, and association with systemic diseases. Treatment is challenging, but th...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Batra P, Cheung W, Meehan SA, Pomeranz M Tags: Dermatol Online J Source Type: journals

Familial benign chronic pemphigus (Hailey-Hailey disease).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 57-year-old woman presented with a 27-year history of vesicles and crusted erosions of the intertriginous folds. Prior treatments had included topical glucocorticoids, mupirocin, and minocycline, all of which provided minimal relief. A skin biopsy specimen was consistent with Hailey-Hailey disease. Hailey-Hailey disease is the result of mutations in the ATP2C1 gene and is characterized by recurrent vesicles and erosions in intertriginous areas. Whereas topical and/or systemic antibiotic/antifungal agents in combination with topical glucocorticoids is the mainstay of treatment, case reports have documented dramatic im...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Warycha M, Patel R, Meehan S, Merola JF Tags: Dermatol Online J Source Type: journals

Hyperimmunoglobulin E syndrome with a novel STAT3 mutation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 35-year-old man with severe eczematous dermatitis and recurrent staphylococcal skin infections, some of which required hospitalization, is presented. Other medical concerns include recurrent oral staphylococcal infections, otitis media, ocular herpes simplex virus keratitis, asthma, steroid-induced gastritis, steroid-induced cataracts, recurrent upper respiratory infections, and acute pharyngitis. Past medical history includes retained dentition of six primary teeth, two episodes of childhood pneumonia that required hospitalization, and three wrist and ankle fractures. Laboratory data showed an eosinophil count of 2,...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Anolik R, Elmariah S, Lehrhoff S, Votava HJ, Martiniuk FT, Levis W Tags: Dermatol Online J Source Type: journals

Pseudoxanthoma elasticum.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present two siblings with pseudoxanthoma elasticum, who have considerable differences in disease related morbidity, which highlights intra-familiar phenotypic heterogeneity. PMID: 19891925 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Gonzalez ME, Votava HJ, Lipkin G, Sanchez M Tags: Dermatol Online J Source Type: journals

Generalized discoid lupus erythematosus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 79-year-old woman presented with a four-year history of generalized, erythematous, indurated plaques on the malar areas, back, and extremities. The lesions had been recalcitrant in the past to topical glucocorticoid therapy. A skin biopsy specimen was diagnostic of discoid lupus erythematosus (DLE). A minority of patients with DLE progress to develop systemic lupus erythematosus although generalized DLE is more frequently associated with systemic involvement than is limited disease. Standard therapy of cutaneous lupus includes broad spectrum sunscreens, topical and intralesional glucocorticoids, and antimalarial agen...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Farley-Loftus R, Mahlberg M, Merola JF, Votava HJ, Meehan S, Stein J, Shupack JL Tags: Dermatol Online J Source Type: journals

Mixed immunobullous disorder most consistent with the IgA-form of epidermolysis bullosa acquisita.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a case of non-scarring, generalized, cutaneous and mucosal subepidermal bullous dermatosis that is characterized histopathologically by a neutrophilic infiltrate and strong linear staining with both IgA and IgG along the basement-membrane zone. Autoantibodies to collagen VII of both the IgA and IgG4 subtypes were detected by indirect immunofluorescence test, which led led to a diagnosis of epidermolysis bullosa aquisita (EBA). EBA is a subepidermal bullous disorder that is mediated by autoantibodies, which are directed against type VII collagen. The distinct clinical presentations of EBA are reviewed and discus...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Rizzo C, Votava HJ, Meehan SA, Kundu R, Franks AG Tags: Dermatol Online J Source Type: journals

Multiple eruptive milia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 61-year-old-man presented with a sudden onset of multiple, hyperpigmented papules with a central punctum on the face, chest, upper back, and arms. Histopathologic examination showed infundibular cysts. These findings are consistent with a diagnosis of multiple eruptive milia, which is a rare disorder that is characterized by the sudden development of crops of milia over weeks to months. They are more extensive in number and distribution than they are in primary milia. Milia may present spontaneously without a known cause, as part of an inherited familial condition, or as part of a genodermatosis. The etiologies are u...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Batra P, Tsou HC, Warycha M, Votava HJ, Stein J Tags: Dermatol Online J Source Type: journals

Neurovascular hamartoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 29-year-old man presented with a large, asymptomatic, brown, hyperpigmented, depressed plaque over his left upper back, which included the scapular area, since childhood. Histopathological analyses of the biopsy specimens was consistent with a rare entity known as neurovascular hamartoma. This uncommon lesion has been reported in two publications, either as a possible marker of the malignant rhabdoid tumor or as a hamartomatous tongue lesion in children. Due to its possible association with the aggressive and often fatal rhabdoid tumor, periodic examination of this lesion may be warranted. PMID: 19891929 [PubMed ...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Lee A, Heidary N, Altiner A, Votava H, Kamino H, Sanchez M Tags: Dermatol Online J Source Type: journals

Interstitial granulomatous dermatitis with arthritis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 54-year-old woman with a history of arthritis presented for a long-standing history of symmetric, indurated plaques on her thighs and lateral aspects of the trunk. Histopathologic examination of skin biopsy specimens was consistent with interstitial granulomatous dermatitis, and a diagnosis of interstitial granulomatous dermatitis with arthritis was made. Administration of topical potent glucocorticoids, intralesional glucocorticoids, and narrow-band ultraviolet B phototherapy, in addition to continuation of systemic glucocorticoids and methotrexate, resulted in improvement of her cutaneous and musculoskeletal diseas...
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Jabbari A, Cheung W, Kamino H, Soter NA Tags: Dermatol Online J Source Type: journals

Genital porokeratosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 22-year-old man presented with a two-year history of warts on the penis, scrotum, and thighs. Physical examination showed multiple annular plaques with thin, threadlike borders on the penis and scrotum. The biopsy specimen showed a cornoid lamella with underlying dyskeratotic cells that was consistent with porokeratosis. Genital porokeratosis is a rare condition that may be misdiagnosed as a sexually transmitted disease. PMID: 19891931 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - November 7, 2009 Category: Dermatology Authors: Liang C, Batra P, Patel R, Kamino H Tags: Dermatol Online J Source Type: journals

Graduates-of-foreign-dermatology residencies and military dermatology residencies and women in academic dermatology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: GFDRs, GMDRs, and women comprise important proportions of full-time faculty members at U.S. dermatology residency programs. PMID: 19624980 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J)
Source: Dermatol Online J - October 3, 2009 Category: Dermatology Authors: Wu JJ, Davis KF, Ramirez CC, Alonso CA, Berman B, Tyring SK Tags: Dermatol Online J Source Type: journals

[Stevens-Johnson syndrome plus intrahepatic cholestasis caused by clindamycin or chlorpheniramine]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a discussion of this case and review the main characteristics of the Stevens Johnson Syndrome. PMID: 19624990 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J)
Source: Dermatol Online J - October 3, 2009 Category: Dermatology Authors: Sahagún Flores JE, Soto Ortiz JA, Tovar Méndez CE, Cárdenas Ochoa EC, Hernández Flores G Tags: Dermatol Online J Source Type: journals

Melanoma screening with serial whole body photographic change detection using Melanoscan technology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The use of an automated, whole-body, diffusely lit digital imaging enclosure to produce serial images, which were then compared, using an astrophysics image display method, enabled a private practice dermatologist to detect melanoma at significantly thinner Breslow depths compared to all other clinical detection paradigms examined in this study. The patients were triaged to scanning using a melanoma risk survey system. The system employed a 24 camera semicircular imaging wall, with front and back views. 10,000 whole body photographic scans were obtained. Privacy was maintained with 128-bit image encryption and off-line...
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Drugge RJ, Nguyen C, Drugge ED, Gliga L, Broderick PA, McClain SA, Brown CC Tags: Dermatol Online J Source Type: journals

Pearls for perfecting the mastoid interpolation flap.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present our suggestions for performing these reconstructions. Ways to optimize results, potential pitfalls, and postoperative care instructions are discussed. Step by step videos are included with this manuscript. PMID: 19723476 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Justiniano H, Eisen DB Tags: Dermatol Online J Source Type: journals

Juvenile dermatomyositis in an 8-year-old boy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report we describe an 8-year-old boy who, besides myopathy, presented with an uncommonly broad spectrum of skin findings that had evolved after summer holidays at the Mediterranean Sea. Upon treatment with intravenous methylprednisolone the patient's condition considerably improved. Our case report illustrates that JDM requires comprehensive evaluation and multidisciplinary management. PMID: 19723477 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Schmieder A, von Komorowski G, Peitsch WK, Goerdt S, Goebeler M Tags: Dermatol Online J Source Type: journals

Anti-phospholipid syndrome preceding a diagnosis of lepromatous leprosy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present this as a case of APS, preceding a diagnosis of lepromatous leprosy. PMID: 19723478 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Kaliyadan F, Bhaskaran M, Dharmaratnam AD, Manoj J, Sreekanth G Tags: Dermatol Online J Source Type: journals

Two cases of primary endonasal leishmaniasis in Sardinia (Italy).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report two cases of endonasal primary Leishmaniasis, which is a very rare event in adult men who are immunocompetent, born in, and residents of Sardinia. The diagnosis was confirmed by the presence of intra and extracellular Leishmania amastigotes in the histological smear. Isoenzymatic characterization identified Leishmania infantum zymodeme MON-111 in both cases. Laboratory and instrumental investigations excluded visceral involvement. Treatment with meglumine antimoniate (Glucantim) intralesional administration, 1 ml weekly for 4-5 weeks, led to complete resolution. The unusual location is likely a reflection an unco...
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Pau M, Atzori L, Aste N, Aste N Tags: Dermatol Online J Source Type: journals

Pemphigus vulgaris presenting as an isolated crusted plaque of the cheek.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A healthy 45-year-old man presented with a three-month history of an isolated enlarging eroded plaque on the left cheek. Pemphigus vulgaris was diagnosed by biopsy and positive direct immunofluorescence. The patient was lost to follow up, but returned two months later with generalized cutaneous involvement without mucosal involvement. He responded rapidly to oral corticosteroid therapy. PMID: 19723480 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Khelifa E, Benmously R, Badri T, Debbiche A, Ben Ayed M, Mokhtar I, Fenniche S Tags: Dermatol Online J Source Type: journals

Pemphigus vulgaris manifesting as a sole persistent lesion on the lower lip: a case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Oral lesions in patients with pemphigus vulgaris commonly manifest as slowly healing erosions with irregular and ill-defined borders of the buccal mucosa and palate. These lesions may be the initial and sole presentation of pemphigus vulgaris. Herein, we describe a 37-year-old woman suffering from pemphigus vulgaris who had only a solitary crusted erosion on the lower lip persisting for eight months without any progression. PMID: 19723481 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Shahidi Dadras M, Qeisari M, Givrad S Tags: Dermatol Online J Source Type: journals

Primary cutaneous nocardiosis with craniocerebral extension: a case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 26-year-old male, a fisherman by occupation, presented with boggy swelling of the scalp and multiple discharging sinuses over the fronto-parietal area for one year. He described a history of periodic trauma to the scalp beginning about one year prior to the onset of the scalp condition. Histopathology suggested a chronic granulomatous suppuration. Magnetic resonance imaging showed intracranial and intra-orbital involvement. Tissue cultures of the sample identified Nocardia brasilienses. The patient was successfully treated with a modified Welsh regimen, given for eight months. PMID: 19723482 [PubMed - in process]...
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Patil SP, Gautam MM, Sodha AA, Khan KJ Tags: Dermatol Online J Source Type: journals

Whitish bullae on the fingers: what is the diagnosis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 56-year-old woman presented with a 6 month history of bullae and whitish plaques of the fingers. She had chronic renal failure, but no joint pains or evidence of arthritis. An aspirate of fluid from a bulla revealed uric acid crystals and serum uric acid was elevated at 16.2 mg/dL. A diagnosis of tophaceous gout was made. PMID: 19723483 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Nogueira A, Duarte AF, Morais P, Magina S, Azevedo F Tags: Dermatol Online J Source Type: journals

A man with erythematous nodules: what is the diagnosis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 65-year-old man presented with an approximately 5-year history of cutaneous nodules of the arms and legs. In addition, physical examination revealed bilateral thickening of ulnar and tibial nerves, distal weakness with hallux extension and finger abduction, and distal hypoesthesia of the left hallux. Histopathological analysis of the skin biopsy specimen showed a dense inflammatory infiltrate in the hypodermis, characterized by vacuolated macrophages containing multiple organisms. The Fite stain was positive confirming the diagnosis of multibacillary leprosy. PMID: 19723484 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 4, 2009 Category: Dermatology Authors: Santos AP, Santos BR, Ayres EL, Xavier MH, Rochael MC Tags: Dermatol Online J Source Type: journals