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Neurofibromatosis and Type 1 diabetes mellitus: an unusual associationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - November 4, 2009 Category: Endocrinology Authors: M. Kamoun, N. Charfi, N. Rekik, M. F. Mnif, F. Mnif, H. Kmiha, Z. Mnif, M. Abid Tags: Letters Source Type: journals

RD Lawrence Lecture 2009 Old genes, new tricks: learning about blood glucose regulation from naturally occurring genetic variation in humansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The study of rare monogenic forms of diabetes and pancreatic B-cell dysfunction provides an unrivalled opportunity to link a specific change in gene function with precise cellular consequences and clinical phenotype in humans. Over the past 20 years there has been considerable success in determining the genetic aetiology of a number of rare monogenic forms of diabetes, which has had a significant impact on both our understanding of normal physiology and on translational medicine. The impact of these discoveries has been substantial, with insights into both developmental biology and normal physiology. There are clear exampl...
Source: Diabetic Medicine - October 8, 2009 Category: Endocrinology Authors: A. L. Gloyn Tags: Review Article Source Type: journals

Putting feet first—national guidance at lastEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - October 1, 2009 Category: Endocrinology Authors: W. Jeffcoate, M. Edmonds, G. Rayman, C. Shearman, L. Stuart, B. Turner Tags: Editorial Source Type: journals

U-shape association between white blood cell count and the risk of diabetes in young Chinese adultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Both low and high levels of WBC count were associated with an increased risk of diabetes in young workers. (Source: Diabetic Medicine)
Source: Diabetic Medicine - September 26, 2009 Category: Endocrinology Authors: X. Du, B. Zhu, G. Hu, W. Mao, S. Wang, H. Zhang, F. Wang, Z. Shi Tags: Original Articles Source Type: journals

Severe neuroglycopaenia secondary to severe hypoglycaemia from serendipitous overdose of gliclazide without adrenergic or autonomic responseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: G. R. Ling, K. Singh, S. Y. Wong, V. K. L. Toh Tags: Letters Source Type: journals

Use of insulin detemir in pregnancy: a report on 10 Type 1 diabetic womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: A. Lapolla, G. Di Cianni, D. Bruttomesso, M. G. Dalfrà, R. Fresa, G. Mello, A. Napoli, T. Romanelli, L. Sciacca, G. Stefanelli, E. Torlone, D. Mannino Tags: Letters Source Type: journals

The threshold for definition of impaired fasting glucose in a Japanese populationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions It may be reasonable to retain the conventional lower FPG limit for IFG and treat FPG values of 5.6[ndash]6.1 mmol/l as non-diabetic hyperglycaemia, considering the four- to fivefold increase in individuals classified as IFG when the new cut-off is applied. Diabet. Med. 26, 1175[ndash]1178 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: K. Inoue, M. Matsumoto, K. Akimoto Tags: Short Report Source Type: journals

Hepatocyte nuclear factor (HNF)1A and HNF4A substitution occurring simultaneously in a family with maturity-onset diabetes of the youngEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions To our knowledge this is the first reported family carrying both a substitution of HNF1A and HNF4A gene simultaneously. The exact contribution of each substitution to the phenotype of our subjects remains to be further elucidated, however, given the high birthweights and the low triglyceride levels in those with both substitutions, it is reasonable that the HNF4A substitution is pathogenic. Diabet. Med. 26, 1172[ndash]1174 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: H. J. B. H. Beijers, M. Losekoot, R. J. Odink, B. Bravenboer Tags: Case Report Source Type: journals

Self-reported history of overweight and its relationship to disordered eating in adolescent girls with Type 1 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Because of the ill-health effects of disordered eating and the higher rate of overweight in adolescent girls with T1D, effective screening tools are warranted. The single question 'Have you ever been overweight?' may be sufficient as a first question to screen for those at high risk for disordered eating attitudes/behaviours and to provide early intervention and prevention. Diabet. Med. 26, 1165[ndash]1171 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: J. T. Markowitz, M. R. Lowe, L. K. Volkening, L. M. B. Laffel Tags: Original Articles Source Type: journals

Pharmacokinetic and pharmacodynamic properties of taspoglutide, a once-weekly, human GLP-1 analogue, after single-dose administration in patients with Type 2 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions A single dose of taspoglutide significantly improved glycaemic parameters in Type 2 diabetes patients for up to 14 days. The formulation was well tolerated and appears suitable for weekly administration. Diabet. Med. 26, 1156[ndash]1164 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: C. Kapitza, T. Heise, P. Birman, K. Jallet, J. Ramis, R. Balena Tags: Original Articles Source Type: journals

Risk factors for gestational diabetes mellitus in Chinese women—a prospective study of 16 286 pregnant women in ChinaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In this large study of GDM in Chinese women, advanced maternal age, pre-pregnancy overweight or obesity and family history of diabetes were confirmed to be risk factors. In addition, a history of recurrent vulvovaginal candidiasis or spontaneous abortion and residency in south China appeared to be novel risk factors in this population. Diabet. Med. 26, 1099[ndash]1104 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: H. Yang, Y. Wei, X. Gao, X. Xu, L. Fan, J. He, Y. Hu, X. Liu, X. Chen, Z. Yang, C. Zhang Tags: Original Articles Source Type: journals

Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These findings identify several novel loci which may contribute to ESRD susceptibility in individuals with Type 1 diabetes. Diabet. Med. 26, 1090[ndash]1098 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - September 3, 2009 Category: Endocrinology Authors: D. W. Craig, M. P. Millis, J. K. DiStefano Tags: Original Articles Source Type: journals

The use of hypothetical scenarios and importance weightings when measuring the impact of diabetes on quality of life. A response to Brose et al.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - September 2, 2009 Category: Endocrinology Authors: J. Speight, M. D. Reaney, K. D. Barnard Tags: Letters Source Type: journals

Exenatide efficacy and safety: a systematic reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In subjects with poorly controlled diabetes, exenatide was associated with a reduction in HbA1c that was similar to introducing another oral agent or insulin. Weight loss may be an advantage with exenatide. Long-term studies in diverse and unselected populations are needed to clarify the benefit vs. harm profile of this drug. (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 27, 2009 Category: Endocrinology Authors: S. L. Norris, N. Lee, S. Thakurta, B. K. S. Chan Tags: Review Article Source Type: journals

Diabetes mellitus may be the earliest and sole manifestation of the H syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - August 21, 2009 Category: Endocrinology Authors: V. Broshtilova, Y. Ramot, V. Molho-Pessach, A. Zlotogorski Tags: Letters Source Type: journals

Plantar pressures in diabetic patients with foot ulcers which have remained healedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions We propose that the mean value for in-shoe pressures reported in these patients be used as a target in footwear prescription for patients with prior ulcers. Although plantar pressure is only one factor in a multifaceted strategy to prevent ulcer recurrence, the quantitative focus on pressure reduction in footwear is likely to have beneficial effects. Diabet. Med. 26, 1141[ndash]1146 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 18, 2009 Category: Endocrinology Authors: T. M. Owings, J. Apelqvist, A. Stenström, M. Becker, S. A. Bus, A. Kalpen, J. S. Ulbrecht, P. R. Cavanagh Tags: Original Articles Source Type: journals

Maternal arterial stiffness in pregnancies affected by Type 1 diabetes mellitusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Pregnancy in women with Type 1 diabetes mellitus is not associated with altered maternal systemic arterial stiffness. However, maternal wave reflections increase with the duration of diabetes. Diabet. Med. 26, 1135[ndash]1140 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 8, 2009 Category: Endocrinology Authors: J. M. Anderson, M. D. Savvidou, C. Kaihura, C. M. McEniery, K. H. Nicolaides Tags: Original Articles Source Type: journals

Conservative management of diabetic forefoot ulceration complicated by underlying osteomyelitis: the benefits of magnetic resonance imagingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions High rates of healing and low rates of amputation were achieved. The use of MRI was associated with long courses of antibiotics, but particularly low relapse rate. Diabet. Med. 26, 1127[ndash]1134 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 8, 2009 Category: Endocrinology Authors: J. Valabhji, N. Oliver, D. Samarasinghe, T. Mali, R. G. J. Gibbs, W. M. W. Gedroyc Tags: Original Articles Source Type: journals

Emergency room visit: a red-flag indicator for poor diabetes careEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Admission to the ER can be used as an indicator for poor quality of diabetes care. There is an association between ER admission and poor quality of diabetes care. Diabet. Med. 26, 1105[ndash]1111 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 8, 2009 Category: Endocrinology Authors: Z. Stern, R. Calderon-Margalit, M. Mazar, M. Brezis, A. Tirosh Tags: Original Articles Source Type: journals

Initiating insulin therapy in elderly patients with Type 2 diabetes: efficacy and safety of lispro mix 25 vs. basal insulin combined with oral glucose-lowering agentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In this elderly subgroup post-hoc analysis, LM25 demonstrated a lower endpoint HbA1c and a higher % of patients reaching HbA1c target of < 7.0%, but with more weight gain and higher rates of hypoglycaemia compared to glargine. Diabet. Med. 26, 1147[ndash]1155 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 4, 2009 Category: Endocrinology Authors: B. H. R. Wolffenbuttel, L. J. Klaff, R. Bhushan, J. L. Fahrbach, H. Jiang, S. Martin Tags: Original Articles Source Type: journals

Intraepidermal nerve fibre density at wrist level in diabetic and non-diabetic patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In mild neuropathy no difference in IENFD at the wrist level could be detected between diabetic and non-diabetic patients. Independent of diabetes, we found IENFD to be higher in hairy skin compared with glabrous skin and higher in females than in males. These results must be taken into consideration when assessing small nerve fibre pathology in the upper extremity. Diabet. Med. 26, 1120[ndash]1126 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 4, 2009 Category: Endocrinology Authors: N. O. B. Thomsen, E. Englund, S. Thrainsdottir, I. Rosén, L. B. Dahlin Tags: Original Articles Source Type: journals

Skeletal muscle microvascular exchange capacity is associated with hyperglycaemia in subjects with central obesityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions We found a strong negative independent association between a measure of skeletal muscle microvascular exchange capacity (Kf) and HbA1c. Kf was associated with almost as much of the variance in HbA1c as fasting plasma glucose. Diabet. Med. 26, 1112[ndash]1119 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 4, 2009 Category: Endocrinology Authors: M. Turzyniecka, S. H. Wild, A. J. Krentz, A. J. Chipperfield, J. Gamble, G. F. Clough, C. D. Byrne Tags: Original Articles Source Type: journals

Comments on Speight et al.'s 'Not all roads lead to Rome—a review of quality of life measurement in adults with diabetes'Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: L. S. Brose, J. Mitchell, C. Bradley Tags: Letters Source Type: journals

Variability in cross-reactivity of novel insulin analogues in immunometric insulin assaysEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: I. Krull, R. Sahli, P. Diem, C. Stettler Tags: Letters Source Type: journals

Testing for monogenic diabetes among children and adolescents with antibody-negative clinically defined Type 1 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The identification of patients with monogenic diabetes from children with clinically defined Type 1 diabetes may be helped by clinical criteria including the absence of pancreatic autoantibodies. (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: O. Rubio-Cabezas, E. L. Edghill, J. Argente, A. T. Hattersley Tags: Short Reports Source Type: journals

Health-related quality of life predicts hospital admission within 1 year in people with diabetes: a nationwide study from TaiwanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In people with diabetes, poorer scores on the PCS of the SF-36 at baseline may provide additional information for assessment of hospital admission risk, independent of other measures of health outcomes. (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: C. L. Li, H. Y. Chang, J. R. Lu Tags: Original Articles Source Type: journals

Trends in yield and effects of screening intervals during 17 years of a large UK community-based diabetic retinopathy screening programmeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Over time the risk of late diagnosis of STDR decreased, possibly attributable to earlier diagnosis of less severe retinopathy, decreasing risk factors and systematic screening. Screening intervals of up to 24 months should be considered for lower risk patients. (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: A. Misra, M. O. Bachmann, R. H. Greenwood, C. Jenkins, A. Shaw, O. Barakat, M. Flatman, C. D. Jones Tags: Original Articles Source Type: journals

Long-term glycaemic control with metformin–sulphonylurea–pioglitazone triple therapy in PROactive (PROactive 17)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Intensifying an existing dual oral therapy regimen to a triple oral regimen by adding pioglitazone to the classical metformin[ndash]sulphonylurea combination resulted in sustained improvements in glycaemic control and reduced progression to insulin therapy. The advantages and disadvantages of adding pioglitazone instead of adding basal insulin should be assessed further. (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: A. J. Scheen, M. H. Tan, D. J. Betteridge, K. Birkeland, O. Schmitz, B. Charbonnel Tags: Original Articles Source Type: journals

Persistent arterial stiffness and endothelial dysfunction following successful pancreas–kidney transplantation in Type 1 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Objective Successful simultaneous pancreas-kidney transplantation (SPK) in Type 1 diabetic (T1DM) patients results in improved cardiovascular outcome and survival. However, it is doubtful whether the impairment of cardiovascular and endothelial function in T1DM can be completely reversed.Methods Pulse-wave velocity, stroke volume, heart rate, serological markers of endothelial dysfunction (soluble intercellular, vascular cell-adhesion molecules, E-selectin, and plasminogen-activator-inhibitor-1) were measured in 10 T1DM patients after SPK with non-diabetic glucose levels, 10 T1DM patients with poor [T1DM>8; glycated haemog...
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: M. Stadler, E. Theuer, C. Anderwald, U. Hanusch-Enserer, M. Auinger, C. Bieglmayer, P. Quehenberger, M. Bischof, T. Kästenbauer, M. Wolzt, O. Wagner, R. Prager Tags: Original Articles Source Type: journals

Serum apolipoprotein C-III in high-density lipoprotein: a key diabetogenic risk factor in TurksEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Serum total apoC-III or its fractions are linearly and inversely associated with smoking, positively with alcohol usage and serum complement C3. The presumably dysfunctional HDL apoC-III is a stronger predictor of Type 2 diabetes than waist girth in Turks. Non-HDL apoC-III predicts strongly the development of MetS as well as incident CHD, independent of HDL cholesterol, BMI and non-lipid factors. The atherogenicity of apoC-III and dysfunctionality of HDL apoC-III carry huge public health implications in Turks. (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: A. Onat, G. Hergenç, E. Ayhan, M. Uğur, H. Kaya, M. Tuncer, G. Can Tags: Original Articles Source Type: journals

Childhood growth and age at diagnosis with Type 1 diabetes in Colorado young peopleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our study provides evidence that increased linear growth, but not increased BMI or weight over time, may account, at least in part, for the younger age at diagnosis of T1D in Colorado children. This finding supports the hypothesis that increasing environmental pressure resulting from changes in potentially preventable risk factors may accelerate the onset of T1D in children. (Source: Diabetic Medicine)
Source: Diabetic Medicine - August 3, 2009 Category: Endocrinology Authors: K. Vehik, R. F. Hamman, D. Lezotte, J. M. Norris, G. J. Klingensmith, D. Dabelea Tags: Original Articles Source Type: journals

J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes: an 8-year follow-up of relatively lean Japanese individualsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions There was a J-shaped relationship between waist circumference and subsequent risk for Type 2 diabetes in relatively lean Japanese individuals; lower pancreatic B-cell function may also increase the risk of diabetes in very lean Japanese people. Diabet. Med. 26, 753[ndash]759 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 31, 2009 Category: Endocrinology Authors: M. Sakurai, K. Miura, T. Takamura, M. Ishizaki, Y. Morikawa, K. Nakamura, K. Yoshita, T. Kido, Y. Naruse, S. Kaneko, H. Nakagawa Tags: Original Articles Source Type: journals

Glycaemia-independent ethnic differences in HbA1c in subjects with impaired glucose toleranceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion South Asians have higher HbA1c levels than Whites despite lower fasting glucose value on OGTT, indicating ethnic differences in HbA1c are due to glycaemia-independent factors (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: T. Likhari, R. Gama Tags: Short Reports Source Type: journals

Psychosocial adjustment to diabetes-related lower limb amputationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Individuals with diabetes-related amputations may be at elevated risk for psychological distress as a result of their co-morbid medical condition. Regular screening for anxiety and depression and the provision of appropriate follow-up care may therefore be advisable in this population. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: L. Coffey, P. Gallagher, O. Horgan, D. Desmond, M. MacLachlan Tags: Short Reports Source Type: journals

Can peer educators influence healthy eating in people with diabetes? Results of a randomized controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In this study of people with Type 2 diabetes, the EPP approach was not effective in changing measures of diabetes control or diet. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: J. E. Cade, S. F. L. Kirk, P. Nelson, L. Hollins, T. Deakin, D. C. Greenwood, E. L. Harvey Tags: Original Articles Source Type: journals

Plasma glucose and hypoglycaemia following exercise in people with Type 1 diabetes: a comparison of three basal insulinsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Insulin detemir was associated with less hypoglycaemia than insulin glargine but not NPH insulin in relatively well-controlled people with Type 1 diabetes during and after exercise. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: V. Arutchelvam, T. Heise, S. Dellweg, B. Elbroend, I. Minns, P. D. Home Tags: Original Articles Source Type: journals

Amitriptyline vs. pregabalin in painful diabetic neuropathy: a randomized double blind clinical trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions As there are few differences between the two treatments in efficacy, pregabalin 150 mg twice daily might be the alternative choice as it is associated with fewer adverse effects in our population. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: D. Bansal, A. Bhansali, D. Hota, A. Chakrabarti, P. Dutta Tags: Original Articles Source Type: journals

Clinical factors associated with gait alterations in diabetic patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion This study indicated that both physiological (strength and proprioception) and cognitive[ndash]behavioural factors (fear of falls) should be considered when treating diabetic patients with gait alterations. Therapists should apply these findings when developing specific fall prevention and treatment programmes. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: L. Allet, S. Armand, R. A. de Bie, A. Golay, Z. Pataky, K. Aminian, E. D. de Bruin Tags: Original Articles Source Type: journals

Risk prediction models for the development of diabetes in Mauritian IndiansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions A diabetes prediction model based on obesity and family history yielded moderate discrimination in Mauritian Indians, which was slightly inferior to the model with the FPG but may be useful in low-income countries to promote identification of people at high risk of diabetes. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: W. G. Gao, Q. Qiao, J. Pitkäniemi, S. Wild, D. Magliano, J. Shaw, S. Söderberg, P. Zimmet, P. Chitson, S. Knowlessur, G. Alberti, J. Tuomilehto Tags: Original Articles Source Type: journals

Increasing incidence and prevalence with limited survival gains among rural Albertans with diabetes: a retrospective cohort study, 1995–2006Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Diabetes prevalence remains highest in men, with the greatest increases seen in men living in rural residences. While mortality rates have declined substantially over the past decade for those people with diabetes living in urban settings, declines in mortality in rural areas have been much more modest (for men) or non-existent (for women). (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: J. A. Johnson, S. U. Balko, G. Hugel, C. Low, L. W. Svenson Tags: Original Articles Source Type: journals

Relative and absolute contributions of postprandial and fasting plasma glucose to daytime hyperglycaemia and HbA1c in subjects with Type 2 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The relative contribution of postprandial glucose to excess hyperglycaemia decreases as glycaemic control deteriorates, being dominant with HbA1c[le] 7.3%, irrespective of the timing of the meal during the day. However, the absolute contribution of postprandial glucose to excess HbA1c does not differ significantly ([sim]1.5%) with varying glycaemic control. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: R. Peter, G. Dunseath, S. D. Luzio, R. Chudleigh, S. R. Choudhury, D. R. Owens Tags: Original Articles Source Type: journals

Insulin resistance is not coupled with defective insulin secretion in primary hyperparathyroidismEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our study confirms a reduction in both basal and stimulated insulin sensitivity in primary hyperparathyroidism, in spite of increased insulin secretion. Moreover, our data show for the first time a significant relationship between hypercalcaemia and insulin sensitivity in this condition. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: F. Tassone, M. Procopio, L. Gianotti, G. Visconti, A. Pia, M. Terzolo, G. Borretta Tags: Original Articles Source Type: journals

Low health-related quality of life is associated with all-cause mortality in patients with diabetes on haemodialysis: the Japan Dialysis Outcomes and Practice Pattern StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The physical component score derived from the SF-36 is an independent risk factor for mortality in patients with diabetes on haemodialysis who generally had very low HRQoL scores. Baseline mental component score was not predictive of mortality. Patient self-reporting regarding the physical component of health status may aid in risk stratification and clinical decision making for patients with diabetes on haemodialysis. Diabet. Med. 26, 921[ndash]927 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: Y. Hayashino, S. Fukuhara, T. Akiba, T. Akizawa, Y. Asano, S. Saito, K. Kurokawa Tags: Original Articles Source Type: journals

Hub-and-spoke model for a 5-day structured patient education programme for people with Type 1 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The benefits of a 5-day structured education programme can be provided to patients with Type 1 diabetes attending centres without the resources to provide the teaching course itself, by a 'hub-and-spoke' methodology. Diabet. Med. 26, 915[ndash]920 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: H. Rogers, E. Turner, G. Thompson, D. Hopkins, S. A. Amiel Tags: Original Articles Source Type: journals

Diabetes-specific family conflict and psychological distress in paediatric Type 1 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions This study highlights the importance of considering the impact of individual psychological functioning on family conflict and also suggests a bidirectional relationship between conflict and glycaemic control. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: L. B. Williams, L. M. B. Laffel, K. K. Hood Tags: Original Articles Source Type: journals

Adherence to a Mediterranean diet and glycaemic control in Type 2 diabetes mellitusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In Type 2 diabetes, greater adherence to a Mediterranean-type diet is associated with lower HbA1c and postprandial glucose levels. Diabet. Med. 26, 900[ndash]907 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: K. Esposito, M. I. Maiorino, C. Di Palo, D. Giugliano Tags: Original Articles Source Type: journals

Randomized trial of custom orthoses and footwear on foot pain and plantar pressure in diabetic peripheral arterial diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Custom foot orthoses significantly reduced plantar pressure compared with the sham, but there were no significant differences between groups for pain or function. The high-quality walking footwear provided to both groups may explain this finding. Footwear should have greater emphasis as the clinical intervention. Diabet. Med. 26, 893[ndash]899 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: J. Burns, C. Wegener, L. Begg, M. Vicaretti, J. Fletcher Tags: Original Articles Source Type: journals

Erythrocytosis in offspring of mothers with Type 1 diabetes—are factors other than insulin critical determinants?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Fetal haematocrit is increased in response to diabetes in pregnancy and is related to maternal glycaemic control. Fetal hyperinsulinism, hyperleptinaemia or macrosomia, although readily demonstrable in this cohort, do not emerge as determinants of raised fetal haematocrit in OT1DM. Both increased birthweight and fetal leptin are negatively associated with platelet count. Diabet. Med. 26, 887[ndash]892 (2009) (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: S. M. Nelson, D. J. Freeman, N. Sattar, R. S. Lindsay Tags: Original Articles Source Type: journals

High prevalence of diabetes and impaired fasting glucose in urban Latin America: the CARMELA StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The prevalence of diabetes and impaired fasting glucose is high in seven major Latin American cities; intervention is needed to avoid substantial medical and socio-economic consequences. CARMELA supports the associations of abdominal obesity, hypertension, elevated serum triglycerides and carotid intima-media thickness with diabetes. (Source: Diabetic Medicine)
Source: Diabetic Medicine - July 30, 2009 Category: Endocrinology Authors: J. Escobedo, L. V. Buitrón, M. F. Velasco, J. C. Ramírez, R. Hernández, A. Macchia, F. Pellegrini, H. Schargrodsky, C. Boissonnet, B. M. Champagne Tags: Original Articles Source Type: journals

Comparing hormonal and symptomatic responses to experimental hypoglycaemia in insulin- and sulphonylurea-treated Type 2 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Sulphonylurea-treated subjects are more symptomatic of hypoglycaemia at a higher glucose level than insulin-treated subjects. This may protect them from severe hypoglycaemia but hinder attainment of glycaemic goals. (Source: Diabetic Medicine)
Source: Diabetic Medicine - June 30, 2009 Category: Endocrinology Authors: P. Choudhary, K. Lonnen, C. J. Emery, I. A. MacDonald, K. M. MacLeod, S. A. Amiel, S. R. Heller Tags: Original Articles Source Type: journals