MNDA expression and its value in differential diagnosis of B-cell non-Hodgkin lymphomas: a comprehensive analysis of a large series of 1293 cases
MNDA (myeloid nuclear differentiation antigen) has been considered as a potential diagnostic marker for marginal zone lymphoma (MZL), but its utility in distinguishing MZL from other B-cell non-Hodgkin lymphom... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 16, 2024 Category: Pathology Authors: Li-Fen Zhang, Yan Zhang, Rou-Hong Shui, Hong-Fen Lu, Wen-Hua Jiang, Xu Cai, Xiao-Qiu Li and Bao-Hua Yu Tags: Research Source Type: research

A case of pancreatic PEComa with prominent inflammatory cell infiltration: the inflammatory subtype is a distinct histologic group of PEComa
PEComa is a mesenchymal tumor that can occur in various organs including the uterus and soft tissues. PEComas are composed of perivascular epithelioid cells, and angiomyolipoma (AML), clear cell sugar tumor (C... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 15, 2024 Category: Pathology Authors: Hikaru Tsukita, Kei Koyama, Takahiro Ishinari, Ayana Takahashi, Ken Miyabe, Michinobu Umakoshi, Makoto Yoshida, Yukitsugu Kudo-Asabe, Akiko Nishida, Naohiko Otsuka, Ouki Yasui, Ikuma Kato, Noriyoshi Fukushima and Akiteru Goto Tags: Case Report Source Type: research

Development of crizotinib-associated renal cyst in a non-small cell lung cancer patient with ALK fusion: a case report and review of the literature
Crizotinib, an oral first-generation tyrosine kinase inhibitor (TKI), is superior to systemic chemotherapy for the treatment of non-small cell lung cancer (NSCLC) with positive rearrangement of anaplastic lymp... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 14, 2024 Category: Pathology Authors: Peng Zhang, JiaHua Xu, Qing Wu, Jianxin Qian and Song Wang Tags: Case Report Source Type: research

Recurrent cementoblastoma with multifocal growth and cellular atypia: a case report
Cementoblastoma is a rare odontogenic tumor characterized by the formation of osteocementum-like tissue on a tooth root directly by neoplastic cementoblasts. Although it is categorized as benign, it has a high... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 8, 2024 Category: Pathology Authors: Kaori Oya, Akinori Takeshita, Kanta Wakamori, Misa Song, Hayato Kimura, Katsutoshi Hirose, Hiroaki Shimamoto, Sunao Sato, Kazuhide Matsunaga, Narikazu Uzawa and Satoru Toyosawa Tags: Case Report Source Type: research

Clinicopathological analysis of 22 M üllerian adenosarcomas and the sequencing of DICER1 mutation
In this study, we conducted an analysis of the clinicopathological characteristics of 22 adenosarcomas, with a particu... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - April 3, 2024 Category: Pathology Authors: Xiaohong Yao, Wei Wang and Ying He Tags: Research Source Type: research

Concurrent KRAS p.G12C mutation and ANK3::RET fusion in a patient with metastatic colorectal cancer: a case report
Colorectal cancer (CRC) frequently involves mutations in the KRAS gene, impacting therapeutic strategies and prognosis. The occurrence of KRAS mutations typically precludes the presence of RET fusions, with curre... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 27, 2024 Category: Pathology Authors: Tillmann Bedau, Carina Heydt, Udo Siebolts, Thomas Zander, Max Kraemer, Heike Loeser, Reinhard Buettner and Alexander Quaas Tags: Case Report Source Type: research

Comprehensive evaluation of the relationship between biomarker profiles and neoadjuvant chemotherapy outcomes for breast cancer patients
Accurately predicting the response to neoadjuvant chemotherapy (NAC) in breast cancer patients is crucial for guiding treatment strategies and enhancing clinical outcomes. Current studies have primarily focuse... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 20, 2024 Category: Pathology Authors: Mijia Wang, Zhendong Wei, Jixia Kong and Haidong Zhao Tags: Research Source Type: research

Extradural spinal melanoma: is it primary or metastatic? A case report with a brief review of literature
Melanocytic lesions involving the central nervous system are extremely rare and pose a diagnostic challenge owing melanoma being the third most common malignancy metastasizing to the spine. Morphology and immu... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 20, 2024 Category: Pathology Authors: Raghav Kapoor, Anurag Mehta, Anila Sharma, Shrinidhi Nathany, Himanshi Diwan and Divya Bansal Tags: Case Report Source Type: research

High incidence of HPV infection in minors with oral squamous cell carcinoma
Oral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human papillomavirus (HPV) infection may trigger the initiation and promote... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 9, 2024 Category: Pathology Authors: Ningxiang Wu, Yonghui Li, Xiaokun Ma, Zhen Huang, Zhuoxuan Chen, Weihua Chen and Ran Zhang Tags: Research Source Type: research

Two lymphoma histotypes and papillary thyroid carcinoma coexisting on Hashimoto ground: a case report and review of the literature
Papillary carcinoma is the most frequent type of thyroid carcinoma, while primary thyroid lymphoma is uncommon disease. The coexistence of these entities has already been described, and the common risk factor ... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 9, 2024 Category: Pathology Authors: Igor Iskra, Maja Ili ć Tomaš, Tatjana Bogović Crnčić, Edvin Kukić, Ita Hadžisejdić, Manuela Avirović and Neva Girotto Tags: Case Report Source Type: research

Histological criteria for selecting patients who need clonality test for non-gastric MALT lymphoma diagnosis
The histological diagnosis of extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) is difficult for pathologists. Recently, digital pathology systems have been widely used... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 8, 2024 Category: Pathology Authors: Dajeong Park and Junhun Cho Tags: Research Source Type: research

Giant cell angiofibroma of gingiva in tuberous sclerosis complex: a case report and literature review
Tuberous sclerosis complex (TSC) is a rare, complex genetic disorder characterized by hamartomas and neoplastic lesions in various organ systems. With the development of radiology and gene testing, the diagnos... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 8, 2024 Category: Pathology Authors: Qiaochu Sun, Jaeyoung Ryu and Young Kim Tags: Case Report Source Type: research

PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating epithelial-mesenchymal transition: an experimental research
Patients with hypopharyngeal carcinoma (HPC) have a poor prognosis mainly because of lymphatic metastasis. This research aimed to determine the PKM2 role in lymphatic metastasis in HPC and the underlying molec... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 2, 2024 Category: Pathology Authors: Xin Zhou, Yanshi Li, Min Pan, Tao Lu, Chuan Liu, Zhihai Wang, Fengxiang Tang and Guohua Hu Tags: Research Source Type: research

Re-evaluating a historic cohort of sinonasal and skull base mucoepidermoid carcinoma: an institutional experience
Primary mucoepidermoid carcinomas (MECs) of the sinonasal tract and nasopharynx are rare entities that represent a diagnostic challenge, especially in biopsy samples. Herein, we present a case series of MECs o... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 1, 2024 Category: Pathology Authors: Chunyan Hu, Lan Lin, Ming Ye, Yifeng Liu, Qiang Huang, Cuncun Yuan, Ji Sun and Hui Sun Tags: Research Source Type: research

Cerebrospinal fluid and blood exosomes as biomarkers for amyotrophic lateral sclerosis; a systematic review
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron disease. Due to the limited knowledge about potential biomarkers that help in early diagnosis and monitoring disease progression, tod... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - March 1, 2024 Category: Pathology Authors: Shahram Darabi, Armin Ariaei, Auob Rustamzadeh, Dariush Afshari, Enam Alhagh Charkhat Gorgich and Leila Darabi Tags: Review Source Type: research