Efficacy of Endoscopic Tissue Adhesive in Patients with Gastrointestinal Tumor Bleeding
ConclusionETA demonstrated excellent immediate hemostasis success rate in GITB cases and showed promising outcomes in prevention re-bleeding. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Effects of Exercise Training on Muscle Mass and Physical Function in Patients with Hepatocellular Carcinoma After Diagnosis: A Systematic Review
ConclusionTogether, the results suggest that patients may benefit from physical exercise training after treatment to improve muscle mass and physical function. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Development and Validation of a Colorectal Cancer Prediction Model: A Nationwide Cohort-Based Study
ConclusionsWe developed an individualized risk prediction model for CRC that can be utilized as a complementary decision support tool for healthcare providers to precisely identify subjects at high risk for CRC and refer them for confirmatory testing. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Coffee, Alcohol, and Artificial Sweeteners Have Temporal Associations with Gastrointestinal Symptoms
ConclusionsCoffee, alcohol, and artificial sweeteners were associated with GI symptoms in this large IBS-predominant sample. Symptom onset is often within 2 h postprandial, but some foods were associated with a delayed response, possibly an important consideration in implementing dietary recommendations. Clinical trials must test the causality of the demonstrated food–symptom associations. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Patients with Celiac Disease Have High Prevalence of Fatty Liver and Metabolic Syndrome
ConclusionsPatients with CeD have a high prevalence of fatty liver and metabolic syndrome which increases further with the initiation of GFD. Patients with CeD should thus be screened and monitored for development of fatty liver and metabolic syndrome. They should be counselled appropriately regarding their diet and inclusion of physical activity in their lifestyle.Graphical Abstract (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Effectiveness of Strategy-Focused Training in Colorectal Endoscopic Submucosal Dissection: A Retrospective Observational Study
Conclusion“Strategy-focused” ESD training consistently yields successful outcomes, effectively adapting to varying difficulty factors in different proficient stages. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
A Novel lncRNA lncRNA-4045 Promotes the Progression of Hepatocellular Carcinoma by Affecting the Expression of AKR1B10
ConclusionLncRNA-4045 may promote HCC via enhancement of the expression of AKR1B10 protein. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Endoscopic Removal of an Obstructing Fecolith at the Entrance of Appendix
(Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 25, 2024 Category: Gastroenterology Source Type: research
Effectiveness of Exercise Interventions on Body Composition, Exercise Capacity, Fatigue, and Quality of Life in Patients with Liver Cirrhosis: A Meta-Analysis of Randomized Controlled Trials
ConclusionsExercise can improve exercise capacity, thigh muscle thickness, and fatigue in patients with cirrhosis, but it does not have a significant impact on fat mass, BMI, or quality of life. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 24, 2024 Category: Gastroenterology Source Type: research
Inpatient Cost Burdens of Treating Chronic Hepatitis B in US Hospitals: A Weighted Analysis of a National Database
ConclusionsWe did not find a significant increase in overall costs with CHB inpatients, regardless of the presence of cirrhosis. However, certain groups are more susceptible to escalating costs. Therefore, increased screening and nuanced vaccination planning must be optimized in order to prevent and mitigate these growing cost burdens on vulnerable populations. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 24, 2024 Category: Gastroenterology Source Type: research
Efficacy and Safety of Endoscopic Resection for Gastric Gastrointestinal Stromal Tumors Originating from the Muscularis Propria
ConclusionsER is proven to be an effective and reasonably safe approach for gastric GISTs originating from the MP. Notably, larger tumor size and irregular shape are identified as risk factors for piecemeal resection during ER procedures. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research
DEAD-Box Helicase 17 circRNA (circDDX17) Reduces Sorafenib Resistance and Tumorigenesis in Hepatocellular Carcinoma
ConclusionOur findings firstly confirmed that circDDX17 suppressed sorafenib resistance and HCC progression by regulating miR-21-5p/PTEN/PI3K/AKT pathway, which may provide novel biomarkers for the diagnosis, treatment and prognosis of HCC.Graphical AbstractSchematic illustration showed that the molecular mechanism by which circDDX17 regulates sorafenib resistance and tumor progression of HCC via the miR-21-5p/PTEN/PI3K/AKT pathway. In HCC cells, the expression of circDDX17 was decreased, and overexpression of circDDX17 promoted cell apoptosis, and enhanced sorafenib sensitivity and reduced EMT process. Besides, circDDX17 ...
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research
Independent Associations of Aortic Calcification with Cirrhosis and Liver Related Mortality in Veterans with Chronic Liver Disease
This study ’s purpose was to evaluate AAC and liver-related death in a cohort of Veterans with chronic liver disease (CLD).MethodsWe utilized the VISN 10 CLD cohort, a regional cohort of Veterans with the three forms of CLD: NAFLD, hepatitis C (HCV), alcohol-associated (ETOH), seen between 2008 and 2014, with abdominal CT scans (n = 3604). Associations between MAC and cirrhosis development, liver decompensation, liver-related death, and overall death were evaluated with Cox proportional hazard models.ResultsThe full cohort demonstrated strong associations of MAC and cirrhosis after adjustment: HR 2.13 (95% CI 1.63, 2.7...
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research
Hepatic and Extrahepatic Characteristics of Autoimmune Hepatitis: A 23-year Hospital-Based Cohort Study
ConclusionIn an Asian country endemic for viral hepatitis, the female-to-male and baseline cirrhosis rates of AIH patients were lower than expected, while over 60% of the patients eventually developed cirrhosis. The high posttherapy relapse rate warrants cautious monitoring, particularly for patients with high baseline Alk-p levels. Baseline age, cirrhosis status and ANA titers are crucial for outcomes. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research
TET2 Is Downregulated in Early Esophageal Squamous Cell Carcinoma and Promotes Esophageal Squamous Cell Malignant Behaviors
ConclusionTET2 downregulation in ESCC potentially influences the necrosis, cell cycle, and tumorigenic ability of esophageal cancer cells, suggesting a role in the onset and progression of esophageal cancer. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 23, 2024 Category: Gastroenterology Source Type: research
