Magnetic resonance imaging short protocols for intraductal papillary mucinous neoplasm (IPMN) surveillance: The time has come
To analyze the diagnostic performance of three short magnetic resonance imaging (MRI) protocols for the follow-up of pancratic intraductal papillary mucinous neoplasms (IPMN). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 13, 2024 Category: Gastroenterology Authors: Mirko D'Onofrio, Luca Geraci, Riccardo Lombardi De Robertis, Nicol ò Cardobi, Alberto Balduzzi, Luisa Tomaiuolo, Eda Bardhi, Niccolò Faccioli, Gregorio Aluffi, Giovanni Marchegiani, Roberto Salvia Tags: Liver, Pancreas and Biliary Tract Source Type: research
Oral Budesonide and low serum albumin levels at surgery are associated with a higher risk of postoperative intra-abdominal septic complications after primary ileocaecal resection for Crohn's disease: A retrospective analysis of 853 consecutive patients
The terminal ileum is the most frequent site of Crohn's Disease (CD) that necessitates surgery. Of the postoperative complications (POCs) associated with ileocaecal resection for CD, intra-abdominal septic complications (IASCs) include anastomotic leak, abscesses, and entero-cutaneous fistula.We aimed to identify predictors of IASCs and severe POCs (Clavien-Dindo ≥3) after primary ileocaecal resection for CD. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 13, 2024 Category: Gastroenterology Authors: Gerti Dajti, Stefano Cardelli, Giacomo Calini, Fernando Rizzello, Paolo Gionchetti, Maria Elena Flacco, Gilberto Poggioli, Matteo Rottoli Tags: Alimentary Tract Source Type: research
Whether and when to biopsy coeliac patients: A never-ending story
Coeliac disease (CD) is an autoimmune enteropathy that primarily affects the small intestine, causing mucosal inflammation and variable villous atrophy. It occurs in genetically predisposed subjects following the ingestion of gluten, a protein complex of cereals such as wheat, barley, rye, whose main fractions are prolamins (including gliadin) and gluten [1]. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 13, 2024 Category: Gastroenterology Authors: Salvatore Cucchiara, Beatrice Leter Tags: Editorial Source Type: research
Controversies in medical vs surgical management of ileocecal crohn's disease
Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) characterized by periods of relapsing luminal inflammation alternating with clinical remissions. Such chronic intestinal inflammation might lead to progressive bowel structural damage, resulting in the development of complications [1]. The Montreal classification perfectly reflects this natural history, describing a non-complicated, strictly inflammatory, CD behavior (B1 phenotype) and two complicated CD phenotypes: the stricturing CD behavior (B2) and the perforating CD behavior (B3). (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 13, 2024 Category: Gastroenterology Authors: L éon Maggiori, David Laharie Tags: Forum Source Type: research
Author's reply: “Bile reflux is associated with Barrett's esophagus”
We extend our gratitude to Dr. Li [1] and colleagues for their keen interest in our research, as expressed through their research letter which comments on our article, entitled “Association between endoscopic evidence of bile reflux and Barrett's esophagus: A large-scale case-control study” [2]. They conducted a meta-analysis including 6 cohort studies and concluded that bile reflux was associated with an increased risk of Barrett's esophagus, consistent with our study results. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 12, 2024 Category: Gastroenterology Authors: Yugo Iwaya Tags: Correspondence Source Type: research
Corrigendum to “Telemedicine in inflammatory bowel disease from its origin to the post pandemic golden age: A narrative review” [Digestive and Liver Disease, Volume 56, Issue 1, January 2024, Pages 1-6]
The authors regret that the author Amalia Di Petrillo's surname was tagged as Petrillo instead of Di Petrillo. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 8, 2024 Category: Gastroenterology Authors: Massimo Claudio Fantini, Erica Loddo, Amalia Di Petrillo, Sara Onali Tags: Corrigendum Source Type: research
Therapeutic endoscopy: Recent updates and future directions
The landscape of therapeutic endoscopy has undergone a remarkable evolution over the past few decades, carving out a niche that merges innovative technology with advanced clinical practice. As we venture further into the 21st century, the horizon of this field continues to expand, driven by rapid advancements in technology and a deeper understanding of gastrointestinal pathology. This review article aims to shed light on the recent advances and future trajectories of therapeutic endoscopy, focusing on pivotal areas such as third space endoscopy, endoscopic resection techniques, artificial endoscopy, endoscopic ultrasound (...
Source: Digestive and Liver Disease - April 6, 2024 Category: Gastroenterology Authors: Zaheer Nabi, D. Nageshwar Reddy Tags: Review Article Source Type: research
Preventing and managing cardiovascular events in patients with inflammatory bowel diseases treated with small-molecule drugs, an international Delphi consensus
Janus kinase (JAK) inhibitors and sphingosine 1 phosphate (S1P) receptor modulators are small molecule drugs (SMDs) approved for IBD treatment. Their use in clinical practice might be limited due to cardiovascular concerns. We aimed to provide guidance on risk assessment, monitoring, and management strategies, aiming to minimize potential cardiovascular risks of SMDs and to facilitate an adequate shared decision-making.A systematic literature search was conducted, and proposed statements were prepared. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 6, 2024 Category: Gastroenterology Authors: Pablo A. Olivera, Axel Dignass, Marla C. Dubinsky, Giovanni Peretto, Paulo G. Kotze, Iris Dotan, Taku Kobayashi, Subrata Ghosh, Fernando Magro, Jose Rocha Faria-Neto, Britta Siegmund, Silvio Danese, Laurent Peyrin-Biroulet Tags: Position Paper Source Type: research
Prevalence of celiac disease in systemic lupus erythematosus, sjogren syndrome and systemic sclerosis: A systematic review and meta-analysis
Celiac disease (CeD) is an immune-mediated disorder affecting the small bowel, associated with genetic factors and increasing global prevalence. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 6, 2024 Category: Gastroenterology Authors: Renato Beas, Euler Altamirano-Farfan, Diego Izquierdo-Veraza, Dalton A. Norwood, Adrian Riva-Moscoso, Ambar Godoy, Eleazar E. Montalvan-Sanchez, Mirian Ramirez, Daniel A. Guifarro, Emily Kitchin, Monika Fischer, Satya Kurada Tags: Meta-Analysis Source Type: research
Association between remnant cholesterol and metabolic dysfunction-associated steatotic liver disease in the elderly
This study aimed to investigate the relationship between RC and MASLD in the elderly Chinese population. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - April 5, 2024 Category: Gastroenterology Authors: Yanqi Lan, Zhinan Guo, Junsheng Dai, Kailin Chen, Youlan Chen Tags: Liver, Pancreas and Biliary Tract Source Type: research
The long intergenic non-coding RNA LINC01140 modulates gastric cancer phenotypes and cancer cell lines aggressiveness
Long-intergenic non-protein coding gene 01140 (LINC01140) a long non-coding RNA is highly expressed in various cancers. However, its biological functions in gastric cancer progression is still unknown. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - March 31, 2024 Category: Gastroenterology Authors: Juhi Singh, Gopeshwar Narayan, Vinod Kumar Dixit Tags: Oncology Source Type: research
Author's reply: The importance of professional training to foster the implementation of Artificial Intelligence in the clinical setting of liver diseases
I have carefully read the letter entitled “Artificial intelligence for liver diseases: The urgency of collaboration” by Cesaretti and colleagues [1], which comments on our review on the advantages and pitfalls of the application of Artificial Intelligence (AI) in the study, management and treatment of liver diseases [2]. Indeed, the com mentary points out questions and interesting insights that require further discussion. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - March 30, 2024 Category: Gastroenterology Authors: Clara Balsano Tags: Correspondence Source Type: research
Combination of Model for End-Stage Liver Disease (MELD) and Sarcopenia predicts mortality after transjugular intrahepatic portosystemic shunt (TIPS)
TIPS is the most effective treatment for portal hypertension. Patient selection remains important to achieving optimal post-TIPS outcomes. The study evaluates 1-year mortality factors in cirrhotic patients receiving TIPS.Methods: 87 cirrhotic patients received a TIPS between 2015 - 2021. Predictors of 1-year and overall mortality were assessed by estimating cumulative incidence functions and Grey's test to adjust for liver transplantation as a risk competing with mortality. Variables with p (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - March 29, 2024 Category: Gastroenterology Authors: Maria Gabriela Delgado, Nando Mertineit, Jaime Bosch, Iris Baumgartner, Annalisa Berzigotti Tags: Liver, Pancreas and Biliary Tract Source Type: research
Resmetirom for the treatment of nonalcoholic steatohepatitis: Evaluating the robustness of available evidence
Non-alcoholic steatohepatitis (NASH), recently renamed metabolic dysfunction-associated steatohepatitis (MASH) [1] is still an orphan condition, with no pharmacological therapy yet approved for use in clinical practice. Nonetheless, the clinical trial landscape in the field is rapidly changing with several molecules currently being studied in Phase 3 clinical programs. In particular, thyroid hormone beta receptor (TRB) agonists have received considerable attention as they reduce de novo lipogenesis, promote fatty acid oxidation, modulate mitophagy and mitochondrial biogenesis as well as cholesterol metabolism and potential...
Source: Digestive and Liver Disease - March 29, 2024 Category: Gastroenterology Authors: Stefano Ciardullo, Alessandro Mantovani Tags: Correspondence Source Type: research
Reticulated platelets are increased and hyper-activated in patients with cirrhosis, especially those with poor outcome
Reticulated platelets (RePLT) are emergency circulating platelets released to contrast peripheral platelet destruction. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - March 28, 2024 Category: Gastroenterology Authors: Alberto Zanetto, Serena Toffanin, Elena Campello, Claudia Maria Radu, Sabrina Gavasso, Patrizia Burra, Francesco Paolo Russo, Marco Senzolo, Paolo Simioni Tags: Liver, Pancreas and Biliary Tract Source Type: research
