Domestic Animal Endocrinology
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - October 9, 2009 Category: Endocrinology Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - October 9, 2009 Category: Endocrinology Source Type: journals
Plasma hormone and metabolite concentrations involved in the somatotropic axis of Japanese Black heifers in association with growth hormone gene polymorphism
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In this study, 10-mo-old Japanese Black heifers with growth hormone (GH) genotypes AA, AB, BB, AC, BC, and CC (N=141) were compared for basal GH, insulin-like growth factor-1 (IGF-1), insulin, ghrelin, glucose, and nonesterified fatty acid (NEFA) concentrations. Growth hormone release was also measured as response to growth hormone–releasing hormone (GHRH) (0.4μg/kg body weight [BW]) using 18 heifers with GH genotypes AA, BB, and CC (n=6 for each group). The genotype AA heifers showed the greatest BW among genotypes (P (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - September 13, 2009 Category: Endocrinology Authors: A. Ardiyanti, F. Abe, H. Kobashikawa, T. Hirayama, T. Sugino, K. Suzuki, K. Katoh Source Type: journals
Effects of GnRH treatment on initiation of pulses of LH, LH release, and subsequent concentrations of progesterone
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In conclusion, timing of GnRH treatment following onset of estrus influenced pulses of LH and subsequent progesterone. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - September 13, 2009 Category: Endocrinology Authors: S.D. Fields, B.L. Perry, G.A. Perry Source Type: journals
Periparturient insulin secretion and whole-body insulin responsiveness in dairy cows showing various forms of ketone pattern with or without puerperal metritis
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Abstract: To study the effect of time and different forms of hyperketonemia, with or without puerperal metritis, on insulin and glucose responses, 31 Holstein cows were subjected to glucose (GTT) and insulin tolerance tests (ITT) between 18 and 22 d before, and on days 7 and 60-70 after calving. Plasma concentrations of beta-hydroxybutyrate (BHB), nonesterified fatty acids, glucose, insulin, insulin-like growth factor I and leptin were measured from 18 d before until 70 d after calving. The revised quick insulin sensitivity index (RQUICKI) was calculated at each time point. First postpartum (PP) ovulation was monitored by ...
Source: Domestic Animal Endocrinology - August 31, 2009 Category: Endocrinology Authors: M. Kerestes, V. Faigl, M. Kulcsár, O. Balogh, J. Földi, H. Fébel, Y. Chilliard, G. Huszenicza Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - August 28, 2009 Category: Endocrinology Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - August 28, 2009 Category: Endocrinology Source Type: journals
Chicken folliculo-stellate cells express thyrotropin receptor mRNA
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Abstract: We investigated the presence of thyrotropin receptor (TSHR) mRNA in chicken pituitary and brain, and quantified the changes in its expression during the last week of embryonic development. We found that in the pituitary gland, TSHR mRNA co-localizes with folliculo-stellate cells but not with thyrotropic cells, suggesting the existence of a paracrine ultra-short thyrotropin feedback loop. TSHR mRNA was also present throughout the diencephalon and various other brain regions, which implies a more general function for thyrotropin in the avian brain. During late embryogenesis, when the activity of the hypothalamo-pit...
Source: Domestic Animal Endocrinology - August 16, 2009 Category: Endocrinology Authors: S.V. Grommen, S. Geysens, V.M. Darras, B. De Groef Source Type: journals
Interactions between genes involved in growth and muscularity in pigs: IGF-2, myostatin, ryanodine receptor 1, and melanocortin-4 receptor
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Abstract: In the swine breeding industry, two economical traits are of particular importance in sires, namely, muscle growth and average daily gain (ADG). These traits are quantitative, which implies that they are under the control of multiple genes. Mutations in these genes, associated with either muscularity or growth, are useful quantitative trait nucleotides (QTN) for unraveling genetic variation of these traits and can be used in marker-assisted selection. Until now, QTN involved in muscle growth and/or ADG in pigs were identified in porcine ryanodine receptor 1 (RYR1), insulin-like growth factor-2 (IGF-2), and melano...
Source: Domestic Animal Endocrinology - August 11, 2009 Category: Endocrinology Authors: A. Stinckens, T. Luyten, K. Van den Maagdenberg, S. Janssens, S. De Smet, M. Georges, N. Buys Source Type: journals
Improvement in insulin resistance and reduction in plasma inflammatory adipokines after weight loss in obese dogs
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Abstract: Obesity is now a major disease of dogs, predisposing to numerous disorders including diabetes mellitus. Adipocytes are active endocrine cells, and human obesity is characterized by derangements in inflammatory adipokine production. However, it is unclear as to whether similar changes occur in dogs. The purpose of the current study was to assess insulin sensitivity and inflammatory adipokine profiles in dogs with naturally occurring obesity and to investigate the effect of subsequent weight loss. Twenty-six overweight dogs were studied, representing a range of breeds and both sexes. All dogs underwent a weight los...
Source: Domestic Animal Endocrinology - August 11, 2009 Category: Endocrinology Authors: A.J. German, M. Hervera, L. Hunter, S.L. Holden, P.J. Morris, V. Biourge, P. Trayhurn Source Type: journals
Effects of immunization against α-inhibin using two adjuvants on daily sperm production and hormone concentrations in ram lambs
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Abstract: Twenty-five ram lambs were immunized against α-inhibin peptide emulsified in Freund's adjuvant (FRA), Emulsigen (EML) containing an oligodeoxynucleotide as an immunostimulant, or adjuvant without α-inhibin antigen (control). Four immunizations were administered during an 85-d period, after which testes were obtained for determination of daily sperm production (DSP) and histological evaluation. α-Inhibin antibody (Ab) titers were 70-fold greater in lambs treated with FRA than in EML-treated ram lambs. α-Inhibin immunization had no effect on testes weight or on plasma concentrations of follicle-stimulating horm...
Source: Domestic Animal Endocrinology - July 30, 2009 Category: Endocrinology Authors: J.L. Voge, J.B. Parker, J.E. Wheaton Source Type: journals
Dynamics of GHRH in third-ventricle cerebrospinal fluid of cattle: Relationship with serum concentrations of GH and responses to appetite-regulating peptides
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Abstract: Objectives were to (1) characterize the relationship of third-ventricle (IIIV) cerebrospinal fluid (CSF) concentrations of growth hormone–releasing hormone (GHRH) with concentrations of GH in the peripheral circulation; and (2) assess the influence of acute administration of appetite-regulating peptides leptin (anti-orexigenic) and neuropeptide Y (NPY; orexigenic) on the release of GHRH. Six mature beef cows fitted with IIIV and jugular vein cannulae were treated intracerebroventricularly with saline, and leptin (600μg) and NPY (500μg) in saline, in a replicated 3×3 Latin square design. Third-ventricle CSF a...
Source: Domestic Animal Endocrinology - July 26, 2009 Category: Endocrinology Authors: M.G. Thomas, M. Amstalden, D.M. Hallford, G.A. Silver, M.D. Garcia, D.H. Keisler, G.L. Williams Source Type: journals
Low doses of estradiol partly inhibit release of GH in sheep without affecting basal levels
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This study sought to determine the effects of estradiol on GH-releasing hormone (GRH)-stimulated GH release in sheep. Growth hormone secretory characteristics, the GH response to GRH, and steady-state GH mRNA concentrations were determined in castrated male lambs treated with 2 different doses of estradiol 17-β for a 28-d experimental period. Although no differences between treatments in mean GH, basal GH, or GH pulse number were observed after 28 d of estradiol treatment, GH pulse amplitude was greater (P (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - July 20, 2009 Category: Endocrinology Authors: A. Hudmon, G. Davenport, E.S. Coleman, J.L. Sartin Source Type: journals
Presenilin enhancer-2 (PSENEN), a component of the γ-secretase complex, is involved in adipocyte differentiation
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This study was conducted to identify genes expressed during adipocyte differentiation of bovine intramuscular fibroblast-like cells using differential display reverse-transcriptase polymerase chain reaction. The presenilin enhancer-2 (PSENEN) gene was found to be down-regulated during adipocyte differentiation of bovine intramuscular fibroblast-like cells. The ectopic expression of bovine PSENEN in 3T3-L1 reduced adipogenesis and the inhibition of endogenous PSENEN by siRNA induced adipogenesis on d 4 of adipocyte differentiation of 3T3-L1 cells. Interestingly, the expression of γ-secretase complex gene-related Notch sign...
Source: Domestic Animal Endocrinology - July 9, 2009 Category: Endocrinology Authors: S.M. Lee, Y.H. Jeong, H.M. Kim, H.Y. Park, D. Yoon, D.H. Kim, S. Saeki, S.J. Moon, M.J. Kang Source Type: journals
Local regulation of corpus luteum development and regression in the cow: Impact of angiogenic and vasoactive factors
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Abstract: The corpus luteum (CL) of the estrous cycle in the cow is a dynamic organ which has a life time of approximately 17-18 days. The main function of the CL is to secrete a large amount of progesterone (P) thereby supporting the achievement of pregnancy. As the CL matures, the steroidogenic cells establish contact with many capillaries and the matured CL is composed of many vascular endothelial cells that account for up to 50% of all CL cells. The bovine CL produces several major angiogenic and vasoactive foctors such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiopoietin-1 ...
Source: Domestic Animal Endocrinology - July 9, 2009 Category: Endocrinology Authors: A. Miyamoto, K. Shirasuna, K. Sasahara Source Type: journals
Estradiol-17β and linseed meal interact to alter visceral organ mass and hormone concentrations from ovariectomized ewes
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Abstract: To evaluate the estrogenic potential of secoisolariciresinol diglycoside (SDG) found in linseed meal (LSM) on visceral organ mass, IGF-I, and thyroid hormone (T3 and T4) concentrations, 48 multiparous, ovariectomized ewes (54.6±1.1kg) were used in a 3×4 factorial arrangement. Main effects were length of LSM feeding (0, 1, 7, or 14 d) and length of exposure to estradiol-17β (E2) implant (0, 6, or 24h prior to tissue collection). Implanting ewes with E2 for 24h increased liver mass relative to empty body weight (EBW; g/kg EBW) compared with ewes implanted for 0 or 6h (P≤0.03), whereas feeding LSM for 14 d decr...
Source: Domestic Animal Endocrinology - June 25, 2009 Category: Endocrinology Authors: M.R. O’Neil, G.P. Lardy, M.E. Wilson, C.O. Lemley, L.P. Reynolds, J.S. Caton, K.A. Vonnahme Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - June 25, 2009 Category: Endocrinology Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - June 25, 2009 Category: Endocrinology Source Type: journals
A miniature condition in Brahman cattle is associated with a single nucleotide mutation within the growth hormone gene
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The objective, therefore, was to clone the GH cDNA from Brooksville miniature Brahman cattle, compare its sequence to normal Brahman cattle, and test the biological activity of the native GH protein. Messenger RNA was isolated from the pituitary, and a cDNA for the protein coding region of the GH gene was amplified by reverse-transcription polymerase chain reaction (PCR) from each of 2 miniature Brahman bulls. The cDNA were cloned into plasmid vectors, and top and bottom strands were sequenced by automated DNA sequencing. The sequence of both cDNA clones derived from miniature cattle differed from Bos indicus GH (GenBank A...
Source: Domestic Animal Endocrinology - June 14, 2009 Category: Endocrinology Authors: B.L. McCormack, C.C. Chase, T.A. Olson, T.H. Elsasser, A.C. Hammond, T.H. Welsh, H. Jiang, R.D. Randel, C.A. Okamura, M.C. Lucy Source Type: journals
Temporal pattern and effect of sex on lipopolysaccharide-induced stress hormone and cytokine response in pigs
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Abstract: The temporal pattern and sex effect of immune and stress hormone responses to a lipopolysaccharide (LPS) challenge were assessed using a pig model. Secretion of the pro-inflammatory cytokines tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6 increased in a time-dependent manner following LPS infusion. There was also a time-dependent increase in secretion of the stress-related hormones cortisol, epinephrine (E), and norepinephrine (NE) following LPS, with peak concentrations attained within 30min. The magnitude of the TNF-α and IL-1β responses were both positively associated (P (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - June 11, 2009 Category: Endocrinology Authors: P.N. Williams, C.T. Collier, J.A. Carroll, T.H. Welsh, J.C. Laurenz Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - June 7, 2009 Category: Endocrinology Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - June 7, 2009 Category: Endocrinology Source Type: journals
Hormone interactions confer specific proliferative and histomorphogenic responses in the porcine mammary gland
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Abstract: Mammary gland growth and morphogenesis are regulated by interactions between hormones as much as by their individual actions. The effect of these interactions on the mammary gland phenotype in species other than rodents is relatively undefined. We investigated the individual and combined effects of estrogen (E), progestin (P), and prolactin (PRL) on mammary gland development in gilts. Pigs were shown to have a ductal-lobular parenchyma that underwent hormone-stimulated progression of terminal ductal lobular unit (TDLU) morphogenesis similar to that in the human breast. Ovariectomy plus hypoprolactinemia abolished...
Source: Domestic Animal Endocrinology - June 3, 2009 Category: Endocrinology Authors: K.C. Horigan, J.F. Trott, A.S. Barndollar, J.M. Scudder, R.M. Blauwiekel, R.C. Hovey Source Type: journals
Interaction between ascorbic acid and follicle-stimulating hormone maintains follicular viability after long-term in vitro culture of caprine preantral follicles
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In conclusion, the combination of 50μg/mL of ascorbic acid and FSH maintained follicular integrity and promoted follicular activation and growth after long-term in vitro culture of caprine preantral follicles. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - June 2, 2009 Category: Endocrinology Authors: R. Rossetto, I.B. Lima-Verde, M.H.T. Matos, M.V.A. Saraiva, F.S. Martins, L.R. Faustino, V.R. Araújo, C.M.G. Silva, K.P.O. Name, S.N. Báo SN, C.C. Campello, J.R. Figueiredo, H. Blume Source Type: journals
Effects of fasting on IGF-I, IGF-II, and IGF-binding protein mRNA concentrations in channel catfish (Ictalurus punctatus)
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Abstract: The effects of fasting on insulin-like growth factor (IGF)-I, IGF-II, and IGF-binding protein (IGFBPs) mRNA in channel catfish were examined. Fed control fish (Fed) were compared to fish that had been fasted for 30 d followed by 15 d of additional feeding (Restricted). Sequence alignment and similarity to orthologous proteins in other vertebrates provided structural evidence that the 3 catfish sequences identified in the present research were IGFBP-1, -2, and -3. Prolonged fasting (30 d) reduced body weight approximately 60% (P (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - May 17, 2009 Category: Endocrinology Authors: B.C. Peterson, G.C. Waldbieser Source Type: journals
Sunflower-seed oil, rapidly-degradable starch, and adiposity up-regulate leptin gene expression in lactating goats
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Abstract: We conducted experiments to evaluate the effects of lipid supplementation and the nature of starchy concentrate on the regulation of leptin synthesis in lactating goats. Multiparous goats in mid- to late lactation received diets based on different forages and containing plant oil or seeds rich in either 18:1c9, 18:2n-6 or 18:3n-3 corresponding to 3%–7% dry matter (DM) as lipid supplements, or diets based on concentrate as either rapidly or slowly degradable starch. The isoenergetic replacement of a part of the concentrate by either oleic sunflower-seed oil, formaldehyde-treated linseeds, or linseed oil did not ...
Source: Domestic Animal Endocrinology - May 14, 2009 Category: Endocrinology Authors: M. Bonnet, C. Delavaud, L. Bernard, J. Rouel, Y. Chilliard Source Type: journals
Possible roles of myostatin and PGC-1α in the increase of skeletal muscle and transformation of fiber type in cold-exposed chicks: Expression of myostatin and PGC-1α in chicks exposed to cold
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This study examined the hypothesis that myostatin and PGC-1α are involved in the increase in skeletal muscle mass and transformation of fiber type in cold-exposed chicks. One-week-old chicks were exposed to acute (24h) or long-term (8d) cold at 4°C or kept warm at 30°C. Acute cold exposure induced a significant increase in the skeletal muscle weight and the ratio of slow- to fast-fiber specific troponin I expression (sTnI/fTnI), accompanied by a significant decrease in lactate dehydrogenase activity. Expression of myostatin mRNA in the muscle was significantly lower in cold-exposed chicks than in the controls, whereas P...
Source: Domestic Animal Endocrinology - May 8, 2009 Category: Endocrinology Authors: Daichi Ijiri, Yukio Kanai, Miho Hirabayashi Source Type: journals
Growth hormone stimulation of serum insulin concentration in cattle: Nutritional dependency and potential mechanisms
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In this study, we determined whether the effect of GH on serum insulin concentration in cattle could be affected by the nutritional levels of the animal and whether GH increased serum insulin concentration in cattle by directly stimulating insulin release or insulin gene expression in the pancreatic islets. Administration of recombinant bovine GH increased serum insulin concentration in nonlactating, nonpregnant beef cows fed a daily concentrate meal in addition to ad libitum hay, but it had no effect in those cows fed hay only. Both GH treatments for 1 and 24h increased insulin concentrations in cultures of pancreatic isl...
Source: Domestic Animal Endocrinology - May 7, 2009 Category: Endocrinology Authors: J. Feng, Z. Gu, M. Wu, F.C. Gwazdauskas, H. Jiang Source Type: journals
Influence of triiodothyronine (T3) on secretion of steroids and thyroid hormone receptor expression in chicken ovarian follicles
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In conclusion, the data indicate that thyroid hormones acting via nuclear receptors are involved in regulation of the pituitary-ovarian axis and processes associated with follicle growth and maturation. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - April 26, 2009 Category: Endocrinology Authors: A. Sechman, K. Pawlowska, J. Rzasa Source Type: journals
Bovine C-terminal octapeptide of RFamide-related peptide-3 suppresses luteinizing hormone (LH) secretion from the pituitary as well as pulsatile LH secretion in bovines
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This study was conducted to evaluate the effects of bovine C-terminal octapeptide of RFRP-3 (RFRP-3-8) on LH secretion from cultured anterior pituitary (AP) cells of cattle, and the effects of RFRP-3-8 injections on pulsatile LH secretion in castrated male calves. The suppressive effect of RFRP-3-8 on LH secretion from AP cells was observed in the presence of gonadotropin-releasing hormone (GnRH), but not in the absence of GnRH in culture media. In another experiment collecting blood samples serially from castrated male calves with repeated intravenous injections of RFRP-3-8 (n=6) or saline (n=6), the RFRP-3-8 group showed...
Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Authors: H. Kadokawa, M. Shibata, Y. Tanaka, T. Kojima, K. Matsumoto, K. Oshima, N. Yamamoto Source Type: journals
Interleukin-1 receptor antagonist expression in the equine endometrium during the peri-implantation period
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Abstract: To identify factors involved in the establishment of pregnancy in the mare, endometrium was collected from day 13 (day 0=day of ovulation) cyclic and day 13, 19, and 25 pregnant animals. From initial cDNA subtraction studies, interleukin-1 receptor antagonist (IL-1RN) mRNA was found as a candidate molecule expressed uniquely in the pregnant endometrium. Expression of IL-1RN mRNA was markedly increased in day 19 and 25 gravid endometrium. In situ hybridization analysis revealed that IL-1RN mRNA was localized to the glandular epithelium. Interleukin-1 receptor antagonist (IL-1RN) protein was found in the extracts o...
Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Authors: S. Haneda, K. Nagaoka, Y. Nambo, M. Kikuchi, Y. Nakano, M. Matsui, Y. Miyake, J.N. Macleod, K. Imakawa Source Type: journals
Cortisol disrupts the ability of estradiol-17β to induce the LH surge in ovariectomized ewes
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Abstract: Stress disrupts the preovulatory luteinizing hormone (LH) surge in females, but the mechanisms are unknown. We tested the hypothesis that cortisol compromises the ability of estrogen to induce a preovulatory-like LH surge in ovariectomized ewes in both the breeding and nonbreeding season. Luteinizing hormone surges were induced in ovariectomized ewes by treatment with progesterone followed by a surge-inducing estradiol-17β (E2) stimulus using a crossover design. The experiment was replicated in the breeding and nonbreeding seasons. Cortisol reduced the incidence of LH surges irrespective of season. Cortisol incr...
Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Authors: B.N. Pierce, I.J. Clarke, A.I. Turner, E.T.A. Rivalland, A.J. Tilbrook Source Type: journals
Rapid calcitonin response to experimental hypercalcemia in healthy horses
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Abstract: Calcium has important physiological functions, and disorders of calcium homeostasis are frequent in horses. We have made important progress understanding equine calcium homeostasis; however, limited information on equine calcitonin (CT) is available, in part because of the lack of validated CT assays. To determine the CT response to high ionized calcium (Ca2+) concentrations in healthy horses, we induced hypercalcemia in 10 healthy horses using a calcium gluconate 23% solution (5mg/kg; 120mL/500kg horse) infused over 4min. Four horses were infused with 120mL of 0.9% NaCl and used as controls. We validated a human...
Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Authors: K.M. Rourke, C.W. Kohn, A.L. Levine, T.J. Rosol, R.E. Toribio Source Type: journals
Somatotropin response in vitro to corticosterone and triiodothyronine during chick embryonic development: Involvement of type I and type II glucocorticoid receptors
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Abstract: Corticosterone (CORT) can stimulate growth hormone (GH) secretion on embryonic day (e) 12 in the chicken. However, CORT failed to induce GH secretion on e20 in a single report, suggesting that regulation of GH production changes during embryonic development. Secretion in response to CORT during embryonic development is modulated by the thyroid hormones triiodothyronine (T3) and thyroxine (T4). Growth hormone responses on e12 involve both glucocorticoid (GR) and mineralocorticoid receptors (MR); however, involvement of MR has not been evaluated past e12. To further define changes in somatotroph responsiveness to C...
Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Authors: K.A. Heuck, L.E. Ellestad, J.A. Proudman, T.E. Porter Source Type: journals
Protein kinase C isoforms in the porcine corpus luteum: Temporal and spatial expression patterns
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Abstract: Porcine corpora lutea (CL) fail to show a luteolytic response to prostaglandin-F-2α (PGF-2α) (ie, luteolytic sensitivity, or LS) until ∼day 13 of the estrous cycle. In view of the importance of protein kinase C (PRKC) in PGF-2α signal transduction, it was hypothesized that limiting levels of 1 or more PRKC isoforms may explain the lack of LS before day 13. This hypothesis was tested by examining expression of mRNA and protein, and the cellular localization patterns of the 11 PRKC isoforms throughout the porcine estrous cycle, to determine whether PRKC expression correlates with and thus may be associated wit...
Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Authors: L.M. Zorrilla, M.S. Irvin, J.E. Gadsby Source Type: journals
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(Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Source Type: journals
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Source: Domestic Animal Endocrinology - April 21, 2009 Category: Endocrinology Source Type: journals
Insulin sensitivity and glucose dynamics during pre-weaning foal development and in response to maternal diet composition
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This study also presents the first data examining glucose and insulin dynamics in developing foals in response to maternal high starch diet. (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - April 8, 2009 Category: Endocrinology Authors: L.A. George, W.B. Staniar, K.H. Treiber, P.A. Harris, R.J. Geor Source Type: journals
Transition period-related changes in the abundance of the mRNAs of adiponectin and its receptors, of visfatin, and of fatty acid binding receptors in adipose tissue of high-yielding dairy cows
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Abstract: Adipose tissue expresses adipokines, which are involved in regulation of energy expenditure, lipid metabolism, and insulin sensitivity. To adapt for the transition from pregnancy to lactation, particularly in high-yielding dairy cows, adipokines, their receptors, and particular G-protein coupled receptors (GPRs) are of potential importance. Signaling by GPR 41 stimulates leptin release via activation by short-chain fatty acids; GPR 43/109A inhibits lipolysis, and GPR 109A thereby mediates the lipid-lowering effects of nicotinic acid and β–hydroxybutyrate. The aim of this study was to compare the mRNA expressio...
Source: Domestic Animal Endocrinology - April 5, 2009 Category: Endocrinology Authors: Anneka Lemor, Afshin Hosseini, Helga Sauerwein, Manfred Mielenz Source Type: journals
Ghrelin differentially modulates the GH secretory response to GHRH between the fed and fasted states in sheep
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Abstract: The effect of energy balance on the growth hormone (GH) secretory responsiveness to growth hormone-releasing hormone (GHRH) has not been determined in ruminant animals. Therefore, we examined the effects of intravenous injections of 0, 3.3, and 6.6μg ghrelin/kg body weight (BW), with and without GHRH at 0.25μg/kg BW, on GH secretory responsiveness in both the fed and fasted sheep. The injections were carried out at 48h (Fasting state) and 3h (Satiety state) after feeding. Blood samples were taken every 10minutes, from 30minutes before to 120minutes after the injection. Low (3.3μg/kg BW) and high (6.6μg/kg BW)...
Source: Domestic Animal Endocrinology - April 2, 2009 Category: Endocrinology Authors: H. Takahashi, Y. Kurose, Y. Suzuki, M. Kojima, T. Yamaguchi, Y. Yoshida, M. Ogino, K. Hodate, Y. Azuma, T. Sugino, M. Kojima, K. Kangawa, Y. Hasegawa, S. Kobayashi Source Type: journals
Gossypol, a polyphenolic aldehyde from cotton plant, interferes with swine granulosa cell function
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This study was therefore conducted to investigate the effect of 5 or 25μg/mL gossypol on swine granulosa cell steroidogenic activity, redox status and Vascular Endothelial Growth Factor (VEGF) production. Study demonstrated that gossypol significantly (P (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - April 1, 2009 Category: Endocrinology Authors: G. Basini, S. Bussolati, L. Baioni, F. Grasselli Source Type: journals
Down-regulation of genes encoding steroidogenic enzymes and hormone receptors in late preovulatory follicles of the cow coincides with an accumulation of intrafollicular steroids
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Abstract: The transformation of the dominant follicle into a functional corpus luteum is accompanied by a profound molecular and morphological reorganization of somatic cell layers. Several studies have focused on gene expression during early processes of follicular differentiation as it relates to recruitment and selection of dominant follicles. However, little information exists on changes of gene expression profiles in late preovulatory follicles. This lack of information is addressed here to elucidate molecular mechanisms behind the LH-induced transition from the large dominant estrogen-active to the preovulatory folli...
Source: Domestic Animal Endocrinology - March 31, 2009 Category: Endocrinology Authors: Marika Nimz, Marion Spitschak, Falk Schneider, Rainer Fürbass, Jens Vanselow Source Type: journals
Effects of short- and long-term fasting on plasma and stomach ghrelin, and the growth hormone/insulin-like growth factor I axis in the tilapia, Oreochromis mossambicus
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Abstract: Ghrelin is a highly conserved peptide hormone secreted by the stomach, which is involved in the regulation of food intake and energy expenditure. Ghrelin stimulates growth hormone (GH) release, and increases appetite in a variety of mammalian and non-mammalian vertebrates, including several fish species. Studies were conducted to investigate the effect of feeding and fasting on plasma and stomach ghrelin, and the growth hormone/insulin-like growth factor I (IGF-I) axis in the Mozambique tilapia, a euryhaline teleost. No postprandial changes in plasma and stomach ghrelin levels or stomach ghrelin mRNA levels were ...
Source: Domestic Animal Endocrinology - March 31, 2009 Category: Endocrinology Authors: Bradley K. Fox, Jason P. Breves, Tetsuya Hirano, E. Gordon Grau Source Type: journals
Ghrelin differentially modulates the GH secretory response to GHRH between the fed and fasted states in sheep.
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In conclusion, the present study has demonstrated for the first time that ghrelin differentially modulates GH secretory response to GHRH according to feeding states in ruminant animals.
PMID: 19342191 [PubMed - as supplied by publisher] (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - March 27, 2009 Category: Endocrinology Authors: Takahashi H, Kurose Y, Suzuki Y, Kojima M, Yamaguchi T, Yoshida Y, Ogino M, Hodate K, Azuma Y, Sugino T, Kojima M, Kangawa K, Hasegawa Y, Kobayashi S Tags: Domest Anim Endocrinol Source Type: journals
Bovine C-terminal octapeptide of RFamide-related peptide-3 suppresses luteinizing hormone (LH) secretion from the pituitary as well as pulsatile LH secretion in bovines.
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In conclusion, our results suggested that RFRP-3-8 suppresses LH secretion from cultured AP cells, as well as LH pulse frequency in cattle.
PMID: 19328642 [PubMed - as supplied by publisher] (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - March 22, 2009 Category: Endocrinology Authors: Kadokawa H, Shibata M, Tanaka Y, Kojima T, Matsumoto K, Oshima K, Yamamoto N Tags: Domest Anim Endocrinol Source Type: journals
Down-regulation of genes encoding steroidogenic enzymes and hormone receptors in late preovulatory follicles of the cow coincides with an accumulation of intrafollicular steroids.
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The transformation of the dominant follicle into a functional corpus luteum is accompanied by a profound molecular and morphological reorganization of somatic cell layers. Several studies have focused on gene expression during early processes of follicular differentiation as it relates to recruitment and selection of dominant follicles. However, little information exists on changes of gene expression profiles in late preovulatory follicles. This lack of information is addressed here to elucidate molecular mechanisms behind the LH-induced transition from the large dominant estrogen-active to the preovulatory follicle, a...
Source: Domestic Animal Endocrinology - March 22, 2009 Category: Endocrinology Authors: Nimz M, Spitschak M, Schneider F, Fürbass R, Vanselow J Tags: Domest Anim Endocrinol Source Type: journals
Effects of short- and long-term fasting on plasma and stomach ghrelin, and the growth hormone/insulin-like growth factor I axis in the tilapia, Oreochromis mossambicus.
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Ghrelin is a highly conserved peptide hormone secreted by the stomach, which is involved in the regulation of food intake and energy expenditure. Ghrelin stimulates growth hormone (GH) release, and increases appetite in a variety of mammalian and non-mammalian vertebrates, including several fish species. Studies were conducted to investigate the effect of feeding and fasting on plasma and stomach ghrelin, and the growth hormone/insulin-like growth factor I (IGF-I) axis in the Mozambique tilapia, a euryhaline teleost. No postprandial changes in plasma and stomach ghrelin levels or stomach ghrelin mRNA levels were observ...
Source: Domestic Animal Endocrinology - March 22, 2009 Category: Endocrinology Authors: Fox BK, Breves JP, Hirano T, Grau EG Tags: Domest Anim Endocrinol Source Type: journals
Gossypol, a polyphenolic aldehyde from cotton plant, interferes with swine granulosa cell function.
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In conclusion, study has demonstrated effecs of gossypol on swine granulosa cell function in vitro. Effects on female swine fertility can not be excluded.
PMID: 19342192 [PubMed - as supplied by publisher] (Source: Domestic Animal Endocrinology)
Source: Domestic Animal Endocrinology - March 22, 2009 Category: Endocrinology Authors: Basini G, Bussolati S, Baioni L, Grasselli F Tags: Domest Anim Endocrinol Source Type: journals
Transition period-related changes in the abundance of the mRNAs of adiponectin and its receptors, of visfatin, and of fatty acid binding receptors in adipose tissue of high-yielding dairy cows.
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Adipose tissue expresses adipokines, which are involved in regulation of energy expenditure, lipid metabolism, and insulin sensitivity. To adapt for the transition from pregnancy to lactation, particularly in high-yielding dairy cows, adipokines, their receptors, and particular G-protein coupled receptors (GPRs) are of potential importance. Signaling by GPR 41 stimulates leptin release via activation by short-chain fatty acids; GPR 43/109A inhibits lipolysis, and GPR 109A thereby mediates the lipid-lowering effects of nicotinic acid and beta-hydroxybutyrate. The aim of this study was to compare the mRNA expression of a...
Source: Domestic Animal Endocrinology - March 22, 2009 Category: Endocrinology Authors: Lemor A, Hosseini A, Sauerwein H, Mielenz M Tags: Domest Anim Endocrinol Source Type: journals
Reproductive responses and nitric oxide activity in Japanese quail, Coturnix coturnix japonica, are altered by specific phase relationships of neural (serotonergic and dopaminergic) oscillations and pineal function.
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The present study investigates the effects of temporal synergism of 5-hydroxytryptophan (5-HTP) and l-dihydroxyphenylalanine (l-DOPA) and pineal function (pinealectomy and melatonin administration) on gonadal response and nitric oxide (NO) activity in Japanese quail. Three-week-old male quails were divided into 9 groups, as follows: (I) control (treated with normal saline); (II) 8-h and (III) 12-h (receiving l-DOPA after the administration of 5-HTP [5mg/100g body weight] at the interval of 8 and 12h, respectively, over a period of 13 days); (IV) SO (sham operated); (V) Px (pinealectomized); (VI) Veh (vehicle treated co...
Source: Domestic Animal Endocrinology - January 23, 2009 Category: Endocrinology Authors: Kumar P, Chaturvedi CM Tags: Domest Anim Endocrinol Source Type: journals
