Assessment of the axial resolution of a compact gamma camera with coded aperture collimator
Handheld gamma cameras with coded aperture collimators are under investigation for intraoperative imaging in nuclear medicine. Coded apertures are a promising collimation technique for applications such as lym... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 21, 2024 Category: Radiology Authors: Tobias Mei ßner, Laura Antonia Cerbone, Paolo Russo, Werner Nahm and Jürgen Hesser Tags: Original research Source Type: research

Comparison of a 3D CZT and conventional SPECT/CT system for quantitative Lu-177 SPECT imaging
Next-generation SPECT/CT systems with CdZnTe (CZT) digital detectors in a ring-like setup are emerging to perform quantitative Lu-177 SPECT imaging in clinical routine. It is essential to assess how the shorte... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 19, 2024 Category: Radiology Authors: Victor Nuttens, Georg Schramm, Yves D ’Asseler and Michel Koole Tags: Original research Source Type: research

155Tb production by cyclotrons: what level of 155Gd enrichment allows clinical applications?
155Tb represents a potentially useful radionuclide for diagnostic medical applications, but its production remains a challenging problem, in spite of the fact that many production routes have been already investi... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 15, 2024 Category: Radiology Authors: Francesca Barbaro, Luciano Canton, Nikolay Uzunov, Laura De Nardo and Laura Melendez-Alafort Tags: Original research Source Type: research

Reduction of [68Ga]Ga-DOTA-TATE injected activity for digital PET/MR in comparison with analogue PET/CT
New digital detectors and block-sequential regularized expectation maximization (BSREM) reconstruction algorithm improve positron emission tomography (PET)/magnetic resonance (MR) image quality. The impact on ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 15, 2024 Category: Radiology Authors: Christina P. W. Cox, Tessa Brabander, Erik Vegt, Quido G. de Lussanet de la Sabloni ère, Laura H. Graven, Frederik A. Verburg and Marcel Segbers Tags: Original research Source Type: research

Sequential deep learning image enhancement models improve diagnostic confidence, lesion detectability, and image reconstruction time in PET
Investigate the potential benefits of sequential deployment of two deep learning (DL) algorithms namely DL-Enhancement (DLE) and DL-based time-of-flight (ToF) (DLT). DLE aims to enhance the rapidly reconstruct... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 15, 2024 Category: Radiology Authors: Meghi Dedja, Abolfazl Mehranian, Kevin M. Bradley, Matthew D. Walker, Patrick A. Fielding, Scott D. Wollenweber, Robert Johnsen and Daniel R. McGowan Tags: Original research Source Type: research

Validation of image-derived input function using a long axial field of view PET/CT scanner for two different tracers
Accurate image-derived input function (IDIF) from highly sensitive large axial field of view (LAFOV) PET/CT scanners could avoid the need of invasive blood sampling for kinetic modelling. The aim is to validat... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 13, 2024 Category: Radiology Authors: Xavier Palard-Novello, Denise Visser, Nelleke Tolboom, Charlotte L. C. Smith, Gerben Zwezerijnen, Elsmarieke van de Giessen, Marijke E. den Hollander, Frederik Barkhof, Albert D. Windhorst, Bart NM van Berckel, Ronald Boellaard and Maqsood Yaqub Tags: Original research Source Type: research

Clinical feasibility study of early 30-minute dynamic FDG-PET scanning protocol for patients with lung lesions
This study aimed to evaluate the clinical feasibility of early 30-minute dynamic 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) positron emission tomography (PET) scanning protocol for patients with lung lesions in co... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 5, 2024 Category: Radiology Authors: Fen Du, Xieraili Wumener, Yarong Zhang, Maoqun Zhang, Jiuhui Zhao, Jinpeng Zhou, Yiluo Li, Bin Huang, Rongliang Wu, Zeheng Xia, Zhiheng Yao, Tao Sun and Ying Liang Tags: Original research Source Type: research

Development and validation of a prognostic nomogram model in locally advanced NSCLC based on metabolic features of PET/CT and hematological inflammatory indicators
We combined the metabolic features of 18F-FDG-PET/CT and hematological inflammatory indicators to establish a predictive model of the outcomes of patients with locally advanced non-small cell lung cancer (LA-NSCL... (Source: EJNMMI Physics)
Source: EJNMMI Physics - March 5, 2024 Category: Radiology Authors: Congjie Wang, Jian Fang, Tingshu Jiang, Shanliang Hu, Ping Wang, Xiuli Liu, Shenchun Zou and Jun Yang Tags: Original research Source Type: research

Correction: Feasibility study of a SiPM-fiber detector for non-invasive measurement of arterial input function for preclinical and clinical positron emission tomography
(Source: EJNMMI Physics)
Source: EJNMMI Physics - March 4, 2024 Category: Radiology Authors: Sara de Scals, Luis Mario Fraile, Jos é Manuel Udías, Laura Martínez Cortés, Marta Oteo, Miguel Ángel Morcillo, José Luis Carreras-Delgado, María Nieves Cabrera-Martín and Samuel España Tags: Correction Source Type: research

Effect of kilovoltage and quality reference mAs on CT-based attenuation correction in 177Lu SPECT/CT imaging: a phantom study
CT-based attenuation correction (CT-AC) plays a major role in accurate activity quantification by SPECT/CT imaging. However, the effect of kilovoltage peak (kVp) and quality-reference mAs (QRM) on the attenuat... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 26, 2024 Category: Radiology Authors: Maikol Salas-Ramirez, Julian Leube, Michael Lassmann and Johannes Tran-Gia Tags: Original research Source Type: research

Fit of biokinetic data in molecular radiotherapy: a machine learning approach
In literature are reported different analytical methods (AM) to choose the proper fit model and to fit data of the time-activity curve (TAC). On the other hand, Machine Learning algorithms (ML) are increasingl... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 22, 2024 Category: Radiology Authors: Davide Ciucci, Bartolomeo Cassano, Salvatore Donatiello, Federica Martire, Antonio Napolitano, Claudia Polito, Elena Solfaroli Camillocci, Gianluca Cervino, Ludovica Pungitore, Claudio Altini, Maria Felicia Villani, Milena Pizzoferro, Maria Carmen Gargane Tags: Original research Source Type: research

Kinetic 18F-FDG PET/CT imaging of hepatocellular carcinoma: a dual input four-compartment model
The endoplasmic reticulum plays an important role in glucose metabolism and has not been explored in the kinetic estimation of hepatocellular carcinoma (HCC) via 18F-fluoro-2-deoxy-d-glucose PET/CT. (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 22, 2024 Category: Radiology Authors: Tao Wang, Yinglei Deng, Sidan Wang, Jianfeng He and Shaobo Wang Tags: Original research Source Type: research

Quantitative calibration of Tb-161 SPECT/CT in view of personalised dosimetry assessment studies
Terbium-161 (161Tb)-based radionuclide therapy poses an alternative to current Lutetium-177 (177Lu) approaches with the additional benefit of secondary Auger and conversion electron emissions capable of deliverin... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 19, 2024 Category: Radiology Authors: Lachlan McIntosh, Price Jackson, Brittany Emmerson, James P. Buteau, Ramin Alipour, Grace Kong and Michael S. Hofman Tags: Original research Source Type: research

Phantom study and clinical application of total-body 18F-FDG PET/CT imaging: How to use small voxel imaging better?
Conventional PET/CT imaging reconstruction is typically performed using voxel size of 3.0 –4.0 mm in three axes. It is hypothesized that a smaller voxel sizes could improve the accuracy of small lesion detectio... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 15, 2024 Category: Radiology Authors: Chi Qi, Xiuli Sui, Haojun Yu, Siyang Wang, Yan Hu, Hongyan Sun, Xinlan Yang, Yihan Wang, Yun Zhou and Hongcheng Shi Tags: Original research Source Type: research

How to obtain the image-derived blood concentration from 89Zr-immuno-PET scans
PET scans using zirconium-89 labelled monoclonal antibodies (89Zr-mAbs), known as 89Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is related to the supply of 89Zr-mAbs in the blood.... (Source: EJNMMI Physics)
Source: EJNMMI Physics - February 7, 2024 Category: Radiology Authors: Jessica E. Wijngaarden, Amina Ahbari, Johanna E. E. Pouw, Henri N. J. M. Greuter, Idris Bahce, Gerben J. C. Zwezerijnen, Dani ëlle J. Vugts, Guus A. M. S. van Dongen, Ronald Boellaard, C. Willemien Menke-van der Houven van Oordt and Marc C. Huisman Tags: Original research Source Type: research