Editorial Board
Publication date: December 2018Source: Egyptian Journal of Basic and Applied Sciences, Volume 5, Issue 4Author(s): (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - December 7, 2018 Category: Science Source Type: research

Corrigendum to “Characterization and applications of exopolysaccharide produced by marine Bacillus altitudinis MSH2014 from Ras Mohamed, Sinai, Egypt” [Egypt. J. Basic Appl. Sci. 5 (2018) 204–209]
Publication date: December 2018Source: Egyptian Journal of Basic and Applied Sciences, Volume 5, Issue 4Author(s): Sahar S. Mohamed, Shaimaa K. Amer, Manal S. Selim, Hala M. Rifaat (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - December 7, 2018 Category: Science Source Type: research

Anti-cancer potential of the lipoidal and flavonoidal compounds from Pisum sativum and Vicia faba peels
Publication date: Available online 14 November 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Amal M. El-Feky, Marwa M. Elbatanony, Marwa M. MounierAbstractFor a long time, plant secondary metabolites have been strongly examined for their antitumor and cytotoxic impacts. These days, there is another pattern of making utilization of the waste products of plants because of their extravagance of numerous phytochemical components and adequacy on human wellbeing. This research work is handling the effect of diversity of lipoidal and phenolic compounds found in the peels of two common edible plants in the M...
Source: Egyptian Journal of Basic and Applied Sciences - November 15, 2018 Category: Science Source Type: research

Ceramide pathway: A novel approach to cancer chemotherapy
Publication date: Available online 28 October 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Mahdi Mashhadi Akbar Boojar, Masoud Mashhadi Akbar Boojar, Sepide GolmohammadAbstractApoptosis or programmed cell death applies as a protected way to remove unwanted cells and plays a determinative role in many important biological processes such as normal development and tissue homeostasis in multicellular organisms. The main purpose of studies in this field is to focus on understanding the related regulatory mechanisms and novel approaches to the discovery of anticancer drugs. Among the apoptotic messenger m...
Source: Egyptian Journal of Basic and Applied Sciences - October 29, 2018 Category: Science Source Type: research

In silico prediction of anticarcinogenic bioactivities of traditional anti-inflammatory plants used by tribal healers in Sathyamangalam wildlife Sanctuary, India
Publication date: Available online 26 October 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Pavithra Chinnasamy, Rajendran ArumugamAbstractThe present study was designed to explore ethnopharmacological anti-inflammatory plants in the anti-cancer drug development. From the specialized local herbalists of the study area, who were treating tumors using anti-inflammatory plants by considering as a type of inflammation and explaining the potential of anti-inflammatory plants in prevalence of early stage's cancer. Interaction results obtained from the herbalists, and in silico PASS and CLC-pred prediction ...
Source: Egyptian Journal of Basic and Applied Sciences - October 27, 2018 Category: Science Source Type: research

Structural, IR spectra NBO, TDDFT, AIM calculation, biological activity and docking property of [1,2,4]-triazolo[3,4-b][1,3,4] thiadiazole
Publication date: Available online 25 October 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Anoop Kumar Pandey, Dharmesh Vikram Shukla, Vijay Singh, Vijay NarayanAbstractIn this paper a complete quantum chemical study of [1,2,4]-triazolo [3,4-b][1,3,4] thiadiazole has been done with the combination of DFT/B3LYP method and 6-311G(d, p) basis set. The vibrational assignments are calculated with the help of PED. By using quantum theory of atoms in the molecule (QTAIM) we have calculated topological parameters at BCP point by which the nature of several intermolecular hydrogen bondings are studied. Elect...
Source: Egyptian Journal of Basic and Applied Sciences - October 26, 2018 Category: Science Source Type: research

Comparison of total phenols, flavonoids and antioxidant potential of local and imported ripe bananas
Publication date: Available online 2 October 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Fatma Said Al Amri, Mohammad Amzad HossainAbstractBananas are globally used trade crops for nutrition and traditional medicine. The following research aims to study different polarity banana extracts from local and imported ripe bananas and determine the amount of phenols and flavonoids contents, and antioxidant potential by applying various spectroscopic methods. The banana extracts were prepared from the powdered banana samples of Pilipino (Cavendish) and Salalah ripe banana (Somali) by the maceration method ...
Source: Egyptian Journal of Basic and Applied Sciences - October 5, 2018 Category: Science Source Type: research

Lipogenesis inhibition and adipogenesis regulation via PPARγ pathway in 3T3-L1 cells by Zingiber cassumunar Roxb. rhizome extracts
This study aim to investigate the lipolytic and anti-adipogenic activity of crude extracts from ZC on in vitro cultures of the mouse adipocyte cell-model, 3T3-L1. Dry rhizome powder was extracted with absolute ethanol and boiled-water. On the exposed pre-adipocytes to the extracts, cytotoxicity was not detected by using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Lipid content and glycerol release were assessed using Oil Red-O and a commercial Adipolysis Assay kits respectively. The extracts exhibited no significant lipolytic activity on the exposed mature-adipocytes, in serial dilutions r...
Source: Egyptian Journal of Basic and Applied Sciences - September 22, 2018 Category: Science Source Type: research

Changes in the dielectric properties of rat lung tissue following x-irradiation
Publication date: Available online 29 August 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Abdelrazek B. Abdelrazzak, Ahmad M. Labeeb, Gamal S. El-BahyAbstractThe Dielectric and Fourier Transform Infrared (FTIR) spectroscopy have been used to investigate the effect of low dose (10 cGy) and high dose (2 Gy) X-rays on the lung of whole-body irradiated rats. The dielectric permittivity ε′, dielectric loss ε″, electric modulus M′ and the imaginary part of the electric modulus M″ measured show changes in the molecular dynamics of the cellular membrane following 10 cGy and 2 Gy-irradiatio...
Source: Egyptian Journal of Basic and Applied Sciences - August 31, 2018 Category: Science Source Type: research

Bioactive potential of secondary metabolites derived from medicinal plant endophytes
Publication date: Available online 6 August 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Prabha Palanichamy, Govindan Krishnamoorthy, Suganya Kannan, Murugan MarudhamuthuAbstractMedicinal plants have been used as an alternative medicine to promote human health and longevity in many regions of the world since ancient times. In recent years, many novel secondary metabolites from higher fungi have been isolated and reported to provide lead compounds for new drug discovery like antimicrobial, antioxidant, and anticancer agents, etc. A total of 42 endophytic fungi were isolated from 11 different medicina...
Source: Egyptian Journal of Basic and Applied Sciences - August 6, 2018 Category: Science Source Type: research

Genetics of congenital cataract, its diagnosis and therapeutics
Publication date: Available online 29 July 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Luqman Khan, Nargis Shaheen, Qaisar Hanif, Shah Fahad, Muhammad UsmanAbstractCongenital cataract is defined as an opacification of the eye lens appearing at birth or shortly thereafter. Congenital cataract is one of the highest significant causes of blindness or optical impairment in the childhood. Cataract, the cloudiness of the lens is the most frequent reason of blindness worldwide, demonstrating nearly half of all causes of loss of sight worldwide. A significant amount of isolated congenital cataract has mono...
Source: Egyptian Journal of Basic and Applied Sciences - August 4, 2018 Category: Science Source Type: research

Genetics of congenital cataract and its diagnosis and therapeutics
Publication date: Available online 29 July 2018Source: Egyptian Journal of Basic and Applied SciencesAuthor(s): Luqman Khan, Nargis Shaheen, Qaisar Hanif, Shah Fahad, Muhammad UsmanAbstractCongenital cataract is defined as an opacification of the eye lens appearing at birth or shortly thereafter. Congenital cataract is one of the highest significant causes of blindness or optical impairment in the childhood. Cataract, the cloudiness of the lens is the most frequent reason of blindness worldwide, demonstrating nearly half of all causes of loss of sight worldwide. A significant amount of isolated congenital cataract has mono...
Source: Egyptian Journal of Basic and Applied Sciences - July 29, 2018 Category: Science Source Type: research

Visfatin gene expression and oxidative stress in pregnancy induced hypertension
This study was conducted with the aim of evaluating the level of visfatin gene expression in placenta and measuring some oxidative stress parameters. Eighty Egyptian patients of newly diagnosed pregnant hypertensive disorder were selected for the study which was recruited from Mansoura University Hospital, Department of Obstetrics and Gynecology and also normotensive pregnant women were collected. The pregnant women groups were classified into four groups: gestational hypertension (n = 20), mild preeclampsia (n = 16), severe preeclampsia (n = 25), chronic hypertension with superimposed preeclampsia (n = 19)...
Source: Egyptian Journal of Basic and Applied Sciences - July 11, 2018 Category: Science Source Type: research

Polyphenon-E encapsulated into chitosan nanoparticles inhibited proliferation and growth of Ehrlich solid tumor in mice
In conclusion, encapsulation of PE into CSNPs provided a good platform for cancer chemotherapy and raised existing application of different polyphenols for nanochemotherapy/prevention.Graphical abstract (Source: Egyptian Journal of Basic and Applied Sciences)
Source: Egyptian Journal of Basic and Applied Sciences - July 11, 2018 Category: Science Source Type: research

Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of benzimidazole derivatives
Publication date: March 2018Source: Egyptian Journal of Basic and Applied Sciences, Volume 5, Issue 1Author(s): Snehlata Yadav, Balasubramanian Narasimhan, Siong Meng Lim, Kalavathy Ramasamy, Mani Vasudevan, Syed Adnan Ali Shah, Abhishek MathurAbstractA series of benzimidazole derivatives (1–20) was synthesized and evaluated for its in vitro antimicrobial, antitubercular and anticancer activities. Compound 10 was found to be the most active antibacterial agent. The compounds active in in vitro evaluation against M. tuberculosis were further assessed for their in vivo activity in mice and for their capacity to inhibit the...
Source: Egyptian Journal of Basic and Applied Sciences - July 11, 2018 Category: Science Source Type: research