Emergency Medicine Clinics of North America
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Contents
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Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Source Type: journals
Forthcoming Issues
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Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Source Type: journals
Foreword
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Anybody who has worked in emergency medicine for more than a few years has undoubtedly noticed a marked increase in the number of patients reporting a past medical history notable for cancer. This change can largely be attributable to 3 major factors. First, diagnostic testing for cancer has improved dramatically during the past decade, resulting in earlier detection of many neoplasms. Second, advances in therapy have increased the lifespan of many patients with cancer, turning the condition from a rapid killer in many cases into a chronic and often manageable disease. Third, advances in diagnosis and management of the 2 o...
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Amal Mattu Source Type: journals
Preface
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This issue of Emergency Medicine Clinics of North America, the second one dedicated to cancer emergencies, focuses on malignancies that affect children along with hematologic and gastrointestinal emergencies related to cancer that present to the emergency department (ED).
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: David M. Spiro, Mohamud Daya Source Type: journals
Gastrointestinal Bleeding in the Cancer Patient
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Gastrointestinal bleeding is a common occurrence in patients with cancer and is a frequent indicator of a gastrointestinal malignancy. Rapid evaluation and treatment is key for the hemodynamically unstable patient. Endoscopy remains the cornerstone of diagnosis and management for cancer patients with gastrointestinal bleeding. The emergency physician should also be aware of other diagnostic and treatment modalities that may be needed to take care of these patients.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Jonathan P. Yarris, Craig R. Warden Tags: Gastrointestinal Emergencies Source Type: journals
Cancer Emergencies: The Acute Abdomen
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This article focuses specifically on patients with cancer who present with an acute abdomen, and it discusses how a concurrent malignancy can shape the differential diagnosis in these cases.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Jonathan S. Ilgen, Amy L. Marr Tags: Gastrointestinal Emergencies Source Type: journals
Hepatic Encephalopathy
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This article reviews the pathogenesis, diagnostic criteria, grading, and management of hepatic encephalopathy.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Yasemen Eroglu, William J. Byrne Tags: Gastrointestinal Emergencies Source Type: journals
Neutropenic Enterocolitis
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Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare but important complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia, and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification by emergency physicians and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Robert L. Cloutier Tags: Gastrointestinal Emergencies Source Type: journals
Management of Acquired Bleeding Problems in Cancer Patients
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Cancer patients can have acquired bleeding problems for many reasons. In this review, an approach to the bleeding patient in the Emergency Department is discussed. Specific issue including coagulation defects, thrombocytopenia, platelet dysfunction, bleeding complications of specific hematological malignancies and due to anticoagulation, are discussed.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Thomas G. DeLoughery Tags: Hematologic Emergencies Source Type: journals
Venous Thrombotic Emergencies
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This article reviews the diagnosis and management of the most common cancer-related thrombotic problem; deep venous thrombosis, pulmonary embolism, and catheterrelated thrombosis. Rarer entities, such as cerebral vein thrombosis and Budd-Chiari syndrome, are also reviewed.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Thomas G. DeLoughery Tags: Hematologic Emergencies Source Type: journals
Myeloproliferative Disorders and the Hyperviscosity Syndrome
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Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Bruce D. Adams, Russell Baker, J. Abraham Lopez, Susan Spencer Tags: Hematologic Emergencies Source Type: journals
Emergency Department Presentation of Childhood Cancer
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This article reviews the most common presentations of childhood cancer and the appropriate initial management in the Emergency Department.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Kellie J. Nazemi, Suman Malempati Tags: Pediatric Oncologic Emergencies Source Type: journals
Management of Pediatric Tumor Lysis Syndrome in the Emergency Department
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Tumor lysis syndrome is most often seen after the treatment of blood and solid malignancies. The resultant hyperkalemia, hyperphosphatemia, hypocalcemia, and hyperuricemia can lead to life threatening complications. Expeditious evaluation and therapy are paramount in preventing the most serious sequelae of acute renal failure and fatal dysrhythmias.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Mark R. Zonfrillo Tags: Pediatric Oncologic Emergencies Source Type: journals
Thrombocytopenia and Anemia in Infants and Children
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This article reviews the common causes of isolated thrombocytopenia and anemia in infancy and childhood.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Michael Recht Tags: Pediatric Oncologic Emergencies Source Type: journals
Fever and Neutropenia in Pediatric Patients with Cancer
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This article reviews the concepts involved in the evaluation and management of febrile, neutropenic, pediatric cancer patients.
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Garth Meckler, Susan Lindemulder Tags: Pediatric Oncologic Emergencies Source Type: journals
Emergency Department Management of Selected Orthopedic Injuries
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The above article, which appeared in the August 2007 issue on “Current Concepts in the Management of the Trauma Patient,” contains an error on page 777 regarding the descriptions of the “Monteggia's Fracture” and the “Galeazzi's Fracture.”
Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Authors: Edward J. Newton, John Love Source Type: journals
Index
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Source: Emergency Medicine Clinics of North America - August 1, 2009 Category: Emergency Medicine Source Type: journals
Contents
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Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Source Type: journals
Forthcoming Issues
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Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Source Type: journals
Foreword
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Anybody who has worked in emergency medicine for more than a few years has undoubtedly noticed a marked increase in the number of patients reporting a past medical history notable for cancer. This change can largely be attributable to three major factors. First, diagnostic testing for cancer has improved dramatically over the past decade, resulting in earlier detection of many neoplasms. Second, advances in therapy have increased the lifespan of many patients with cancer, turning the condition from a rapid killer in many cases into a chronic and often manageable disease. Third, advances in diagnosis and management of the t...
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Amal Mattu Source Type: journals
Preface
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Cancer will affect one in three people at some point in their lifetime and is primarily a disease of those over the age of 50. As emergency department (ED) physicians and providers see increasing numbers of cancer patients as the population ages, they need to be well prepared to deal with cancer-specific emergencies. Since the last clinics issue dedicated to this topic in 1993, there have been many advances in cancer treatment (palliative and curative), including more targeted therapies that will hopefully maximize benefit and reduce side effects.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Mohamud Daya, Charles R. Thomas Source Type: journals
Management of Cancer-Related Pain
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Patients and families struggling with cancer fear pain more than any other physical symptom. There are also significant barriers to optimal pain management in the emergency setting, including lack of knowledge, inexperienced clinicians, myths about addiction, and fears of complications after discharge. In this article, we review the assessment and management options for cancer-related pain based on the World Health Organization (WHO) 3-step approach.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Paul L. DeSandre, Tammie E. Quest Tags: GENERAL Source Type: journals
Optimal Management of Malignant Epidural Spinal Cord Compression
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Malignant epidural spinal cord compression (MESCC) is a common neurologic complication of cancer. MESCC is a medical emergency that needs rapid diagnosis and treatment to prevent paraplegia. Patients with malignancy who present with new onset of neurologic signs and symptoms should undergo emergent evaluation including magnetic resonance imaging of the entire spine. If MESCC is diagnosed, corticosteroids should be administered. Simultaneously, spine surgery and oncology teams should be immediately consulted. If indicated, patients should undergo maximal tumor resection and stabilization, followed by postoperative radiother...
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Hai Sun, Andrew N. Nemecek Tags: NEUROLOGIC EMERGENCIES Source Type: journals
Cerebral Edema, Altered Mental Status, Seizures, Acute Stroke, Leptomeningeal Metastases, and Paraneoplastic Syndrome
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This article reviews common neuro-oncologic syndromes that may lead to urgent evaluation in the emergency department, including cerebral edema, altered mental status, seizures, acute stroke, leptomeningeal metastases, and paraneoplastic neurologic syndromes.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Denise M. Damek Tags: NEUROLOGIC EMERGENCIES Source Type: journals
Emergent Management of Malignancy-Related Acute Airway Obstruction
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Acute obstruction of the airway in the emergent situation results from a wide variety of malignant and benign disease processes. Acute management involves establishing a secure and patent route for adequate gas exchange. This requires rapid determination of the location of the obstruction and nature of the obstruction followed by a thoughtful management approach based on findings. Difficult anatomy, hemorrhage, dense secretions, inflammation, and bulky tumor mass can significantly complicate the task of clearing the airway. Obstruction of the central airways by malignant tumor is associated with poor prognosis, but quality...
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Pierre R. Theodore Tags: CARDIOPULMONARY EMERGENCIES Source Type: journals
Superior Vena Cava Syndrome
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Superior vena cava syndrome (SVCS) is a common complication of malignancy. The epidemiology, presentation, and diagnostic evaluation of patients presenting with the syndrome are reviewed. Management options including chemotherapy and radiation therapy (RT) and the role of endovascular stents are discussed along with the evidence for each of the therapeutic options.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Jonathan F. Wan, Andrea Bezjak Tags: CARDIOPULMONARY EMERGENCIES Source Type: journals
Electrolyte Complications of Malignancy
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A thorough working knowledge of the diagnosis and treatment of life-threatening electrolyte abnormalities in cancer patients, especially hyponatremia, hypoglycemia, and hypercalcemia, is essential to the successful practice of emergency medicine. Although most minor abnormalities have no specific treatment, severe clinical manifestations of several notable electrolytes occur with significant frequency in the setting of malignancy. The treatment of life-threatening electrolyte abnormalities is reviewed here. Promising future treatments directed at the underlying physiology are also introduced.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Robert F. Kacprowicz, Jeremy D. Lloyd Tags: METABOLIC EMERGENCIES Source Type: journals
Adrenal Insufficiency and Other Adrenal Oncologic Emergencies
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Normal function of the adrenal gland can be disrupted not only by metastases of nonadrenal cancers but also by their treatment. In addition, tumors of the adrenal gland itself can cause disease by hypersecretion of a variety of hormones, adrenal gland destruction with inadequate production of cortisol, and by metastasis to other sites. Although rare, abnormal adrenal function should be considered in the appropriate clinical settings as failure to recognize and treat can result in significant morbidity and mortality. The adrenal “incidentaloma” is a frequent finding of abdominal radiologic studies. All patients with an ...
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Yael R. Taub, Robert W. Wolford Tags: METABOLIC EMERGENCIES Source Type: journals
Renal Complications in Oncologic Patients
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This article focuses on several of these etiologies, such as tumor lysis syndrome (TLS) and thrombotic microangiopathy (TMA), which are unique threats faced by the oncologic patient.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Melissa L. Givens, Joy Wethern Tags: METABOLIC EMERGENCIES Source Type: journals
Radiation Therapy–Related Toxicity (Including Pneumonitis and Fibrosis)
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This article is designed to acquaint emergency medicine physicians with common, expected, and potential acute and late complications of RT.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Rahul R. Chopra, Jeffrey A. Bogart Tags: TREATMENT-RELATED COMPLICATIONS PRESENTING TO THE EMERGENCY DEPARTMENT Source Type: journals
Emergencies Related to Cancer Chemotherapy and Hematopoietic Stem Cell Transplantation
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As a vast majority of oncologic treatments are being administered in the outpatient setting, emergency department (ED) physicians are increasingly encountering patients who present with a wide array of toxicities that are a direct effect of chemotherapy. This review aims to highlight the most often encountered and clinically relevant toxicities of the more commonly administered chemotherapeutic drugs. In addition, because stem cell transplantation is being used increasingly for various malignancies, a brief introduction to post-transplant complications is included.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: David E. Adelberg, Michael R. Bishop Tags: TREATMENT-RELATED COMPLICATIONS PRESENTING TO THE EMERGENCY DEPARTMENT Source Type: journals
Caring for Patients with Malignancy in the Emergency Department: Patient–Provider Interactions
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Patients with malignancy and caregivers can present to the emergency department (ED) under stress and fatigue as a result of the intensity of energy required to cope with the physical, psychological, social, and spiritual aspects of their illness. When interacting with patients and families, emergency clinicians should be aware of patient, family, and caregiver coping, which may be impaired due to the chronic, serious illness. The emergency clinician should not be surprised that conflicts may arise between patients and providers as a result of fatigue and stress. Strategies to manage conflict can be employed.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Tammie E. Quest, Placid Bone Tags: ETHICAL DILEMMAS AND END-OF-LIFE ISSUES Source Type: journals
Treating Cancer Patients who Are Near the End of Life in the Emergency Department
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Cancer-related visits to the emergency department (ED) can be expected to increase in the next decade as the population ages. Some of the these patients and their caregivers will come to the ED without prior end-of-life care planning, and others will require modification of prior plans based on disease progression. In this article, we discuss some of these end-of-life issues related to and including those of legal documents, transmission of patient wishes, limiting factors in implementing those wishes, and the new horizon of palliative care in the ED.
Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Authors: Dawn Felch Rondeau, Terri A. Schmidt Tags: ETHICAL DILEMMAS AND END-OF-LIFE ISSUES Source Type: journals
Index
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Source: Emergency Medicine Clinics of North America - May 1, 2009 Category: Emergency Medicine Tags: ETHICAL DILEMMAS AND END-OF-LIFE ISSUES Source Type: journals
Glycemic Control and the Injured Brain.
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This article reviews the epidemiology of the problem, relevant pathophysiology, the use of tight glycemic control therapy in other populations, and the potential for tight glycemic control as a way to improve outcomes after acute neurologic illness and injury.
PMID: 19218025 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Gentile NT, Siren K Tags: Emerg Med Clin North Am Source Type: journals
Therapeutic Hypothermia for Neuroprotection.
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This review briefly discusses induced therapeutic hypothermia (TH), which represents the intentional induction of a lowered core body temperature of 35 degrees C or less. The focus is on resuscitative or postarrest hypothermia, the data that support it, and the practical issues pertaining to TH implementation.
PMID: 19218024 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Dine CJ, Abella BS Tags: Emerg Med Clin North Am Source Type: journals
Enhancing Community Delivery of Tissue Plasminogen Activator in Stroke Through Community-Academic Collaborative Clinical Knowledge Translation.
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This article reviews the history of tPA use in stroke as a case study of a breakdown of knowledge translation in emergency medicine. It reviews knowledge translation concepts and theory and explores practical community-academic collaborative methods based on these tenets to enhance acute stroke care delivery in the community setting.
PMID: 19218023 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Scott PA Tags: Emerg Med Clin North Am Source Type: journals
Emergency Treatment of Status Epilepticus: Current Thinking.
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Current thinking about the acute treatment of status epilepticus (SE) emphasizes a more aggressive clinical approach to this common life-threatening neurologic emergency. In this review, the authors consider four concepts that can accelerate effective treatment of SE. These include (1) updating the definition of SE to make it more clinically relevant, (2) consideration of faster ways to initiate first-line benzodiazepine therapy in the prehospital environment, (3) moving to second-line agents more quickly in refractory status in the emergency department, and (4) increasing detection and treatment of unrecognized noncon...
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Millikan D, Rice B, Silbergleit R Tags: Emerg Med Clin North Am Source Type: journals
Central Nervous System Infections.
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This article describes the changing pattern and epidemiology of a variety of common central nervous system infections, including meningitis, encephalitis, and brain abscesses, and reviews pathophysiology and the most current approach to clinical diagnosis, treatment, and disposition from the emergency physician perspective.
PMID: 19218021 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Somand D, Meurer W Tags: Emerg Med Clin North Am Source Type: journals
Diagnosis and Management of the Primary Headache Disorders in the Emergency Department Setting.
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This article reviews the diagnostic criteria and management strategies for the primary headache disorders.
PMID: 19218020 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Friedman BW, Grosberg BM Tags: Emerg Med Clin North Am Source Type: journals
Management of Transient Ischemia Attacks in the Twenty-First Century.
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Patients who have a transient ischemic attack (TIA) represent a group that may appear well but are at high risk for stroke within 90 days. Management of patients who have a TIA requires an understanding of the short-term risk for stroke to guide acute management and the long-term benefits to medical and surgical therapies. The initial emergency department (ED) evaluation may be supplemented with simple TIA stroke risk scores to estimate short-term stroke risk. The addition of MRI provides yet more information regarding stroke risks, while identifying some specific causes of TIA. Extended testing may not be feasible in ...
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Ross M, Nahab F Tags: Emerg Med Clin North Am Source Type: journals
Vertigo and Dizziness in the Emergency Department.
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Understanding three peripheral vestibular disorders-vestibular neuritis, benign paroxysmal positional vertigo, and Meniere's disease-is the key to the evaluation and management of vertigo and dizziness presentations in the emergency department. Each of these benign disorders is a common cause of a broad category of dizziness presentation. In addition, each of these disorders has characteristic features that allow for a bedside diagnosis. An effective strategy for "ruling-out" a serious disorder, such as stroke, is "ruling-in" a peripheral vestibular disorder. In this article a focus is on the key features of these diso...
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Kerber KA Tags: Emerg Med Clin North Am Source Type: journals
Clinical Nihilism in Neuroemergencies.
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This article examines the role of prognostication early after neuroemergencies, the potential impact of early treatment limitations, and how these may relate to communication with patients and surrogate decision makers in the context of these acute neurologic events.
PMID: 19218017 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Hemphill JC, White DB Tags: Emerg Med Clin North Am Source Type: journals
Critical Care Transport of Patients Who Have Acute Neurological Emergencies.
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This article reviews the special questions and issues in critical care transport related specifically to the care of patients who have neurologic emergencies. It first considers potential indications for transport and reviews attempts to create a hierarchical stroke center system akin to that developed for trauma care. It then discusses therapeutic concerns relating to the transport environment and the use of specific interventions, including the effects of end-tidal CO(2) monitoring on intracranial pressure, patient outcomes after traumatic brain injury, and opportunities to initiate therapeutic hypothermia in comatose su...
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Uren B, Lowell MJ, Silbergleit R Tags: Emerg Med Clin North Am Source Type: journals
Rapid Focused Neurological Assessment in the Emergency Department and ICU.
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This article discusses how to direct the history and examination in patients who have focal complaints, possible strokes affecting the anterior or posterior circulations, neck or back pain, neuromuscular complaints, global symptoms, or nonanatomic complaints.
PMID: 19218015 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Goldstein JN, Greer DM Tags: Emerg Med Clin North Am Source Type: journals
Preface.
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PMID: 19218014 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Silbergleit R, Geocadin RG Tags: Emerg Med Clin North Am Source Type: journals
Foreword.
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PMID: 19218013 [PubMed - as supplied by publisher]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Mattu A Tags: Emerg Med Clin North Am Source Type: journals
Neurological emergencies are a common presentation. Preface.
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PMID: 19218014 [PubMed - in process]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Silbergleit R, Geocadin RG Tags: Emerg Med Clin North Am Source Type: journals
The brain has long been considered the "black box" of the human body. Foreword.
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PMID: 19218013 [PubMed - in process]
Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Authors: Mattu A Tags: Emerg Med Clin North Am Source Type: journals
Contents
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Source: Emergency Medicine Clinics of North America - February 1, 2009 Category: Emergency Medicine Source Type: journals
