The Authors Respond
No abstract available (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Letters Source Type: research
Re. Assessing Uncontrolled Confounding in Associations of Being Overweight With All-Cause Mortality
No abstract available (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Letters Source Type: research
The Authors Respond
No abstract available (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Letters Source Type: research
Re. A Multipollutant Approach to Estimating Causal Effects of Air Pollution Mixtures on Overall Mortality in a Large, Prospective Cohort
No abstract available (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Letters Source Type: research
Could Smoking Initiation Among Youth by E-cigarettes Warrant a Shorter Definition for Epidemiology?
No abstract available (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Letters Source Type: research
Heterogeneity in Disparities in Life Expectancy Across US Metropolitan Areas
Conclusions:
Sociodemographic and policy factors likely help explain variation in life expectancy disparities within and across metro areas. (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Psychosocial Epidemiology Source Type: research
The Contribution of Health Behaviors to Depression Risk Across Birth Cohorts
Conclusion:
Increased obesity levels were associated with exacerbated depression risk in recent birth cohorts in the United States, while drinking patterns only played a minor role. (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Psychosocial Epidemiology Source Type: research
Gestational Hypertensive Disorders and Maternal Breast Cancer Risk in a Nationwide Cohort of 40,720 Parous Women
Conclusions:
History of a gestational hypertensive disorder was not associated with breast cancer risk in a cohort of women with a first-degree family history of breast cancer. (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Perinatal Epidemiology Source Type: research
We Don’t Talk About Consistency: The Unspoken Challenge of Identifying Mediated Effects in Perinatal Epidemiology
No abstract available (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Perinatal Epidemiology Source Type: research
Understanding Etiologic Pathways Through Multiple Sequential Mediators: An Application in Perinatal Epidemiology
Conclusions:
Through an application of causal mediation analysis with sequential mediators, we uncovered new insights into the pathways along which abruption impacts perinatal mortality. (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Perinatal Epidemiology Source Type: research
Log-transformation of Independent Variables: Must We?
In this study, we evaluated the validity of motivations underlying the decision to log-transform an independent variable using simulations, considering eight scenarios that can give rise to skewed X and normal Y. Our simulation study demonstrates that (1) if the skewness of exposure did not arise from a biasing factor (e.g., measurement error), the analytic approach with the best overall model fit best reflected the underlying outcome generating methods and was least biased, regardless of the skewness of X and (2) all estimates were biased if the skewness of exposure was a consequence of a biasing factor. We additionally i...
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Methods Source Type: research
Exact Mediation Analysis for Ordinal Outcome and Binary Mediator
With reference to a single mediator context, this brief report presents a model-based strategy to estimate counterfactual direct and indirect effects when the response variable is ordinal and the mediator is binary. Postulating a logistic regression model for the mediator and a cumulative logit model for the outcome, we present the exact parametric formulation of the causal effects, thereby extending previous work that only contained approximated results. The identification conditions are equivalent to the ones already established in the literature. The effects can be estimated by making use of standard statistical softwar...
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Methods Source Type: research
Negative Control Exposures: Causal Effect Identifiability and Use in Probabilistic-bias and Bayesian Analyses With Unmeasured Confounders
Conclusions:
We used dichotomous negative control exposure to identify causal effects when a confounder was unmeasured under strong assumptions. It may be possible to relax assumptions and the negative control exposure could prove helpful for probabilistic bias analyses and Bayesian analyses. (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Methods Source Type: research
Homogeneity in the Instrument-exposure Association and Point Estimation Using Binary Instrumental Variables
Conclusions:
For binary instruments, instrument-exposure additive homogeneity identifies the ADE if the exposure is also binary. Otherwise, additional assumptions (such as additive linearity of the exposure-outcome effect) are required. (Source: Epidemiology)
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Methods Source Type: research
On the Conventional Definition of Path-specific Effects: Fully Mediated Interaction With Multiple Ordered Mediators
Path-specific effects are a critical measure for assessing mediation in the presence of multiple mediators. However, the conventional definition of path-specific effects has generated controversy because it often causes misinterpretation of the results of multiple mediator analysis. For in-depth analysis of this issue, we propose the concept of decomposing fully mediated interaction from the average causal effect. We show that misclassification of fully mediated interaction is the main cause of misinterpretation of path-specific effects. We propose two strategies for specifying fully mediated interaction: isolating and rec...
Source: Epidemiology - October 20, 2022 Category: Epidemiology Tags: Methods Source Type: research
