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A clinicopathological study of basaloid squamous carcinoma of the esophagusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract We reviewed the clinicopathological characteristics of 14 patients who underwent resection of basaloid squamous carcinoma (BSC) of the esophagus. The mean age was 65.3 years, and all patients were male. Seven patients had superficial BSCs and 7 had advanced BSCs. BSCs were associated with high rates of lymph node metastases and venous invasion. With regard to immunohistochemistry, the rate of cyclin D1 expression was higher (13/14), and the preservation rate of E-cadherin expression was lower (4/14), than that seen in ordinary esophageal squamous cell carcinoma. Squamous cell carcinoma components we...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Clinical features of primary small cell carcinoma of the thoracic esophagus: a retrospective analysis of 12 surgically resected casesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The prognosis of surgically resected cases of esophageal small cell carcinoma is poor; therefore, either chemotherapy or chemoradiotherapy should be administered to such cases. Furthermore, improved understanding of the biological characteristics of this type of tumor will result in the development of new therapeutic strategies, which are expected to improve patient outcome. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-009-0197-9Authors Noriaki Sadanaga, Kyushu University Department of Surgery and Science, Graduate School of Medical Sciences Fukuoka 812-8582 Japa...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

A case of sigmoid-type achalasia treated with hand-assisted laparoscopic Heller-Dor procedureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A male patient in his thirties was referred with dysphagia lasting 8 years. He had a history of a laparotomy for a testicular tumor in his twenties. From an upper gastrointestinal contrast X-ray, he was diagnosed to have sigmoid-type achalasia (greatest transverse diameter, 80 mm). Hand-assisted laparoscopic Heller-Dor surgery was performed because straightening of the esophagus using only a laparoscope was difficult due to the marked curvature of the lower mediastinal part of the esophagus and the history of a laparotomy. The postoperative course was excellent; the patient was discharged on day 9. ...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Evaluation of the feasibility and safety of immediate extubation after esophagectomy with extended radical three-field lymph node dissection for thoracic esophageal cancersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions IE is feasible and safe even after transthoracic esophagectomy with 3FLND. To avoid the possible disadvantages of MV after surgery, IE can be a standard protocol for postoperative management after transthoracic esophagectomy with radical lymph node dissection. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-009-0198-8Authors Yasushi Toh, National Kyushu Cancer Center Department of Gastroenterological Surgery 3-1-1 Notame, Minami-ku Fukuoka 811-1395 JapanEiji Oki, National Kyushu Cancer Center Department of Gastroenterological Surgery 3-1-1 Notame, Minami-ku Fukuoka ...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Therapeutic effectiveness of chemoradiotherapy for carcinosarcoma of the esophagus: two case reports and a review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report two patients with carcinosarcoma of the esophagus who received neoadjuvant chemoradiotherapy and underwent curative resection. Patient 1 was a 50-year-old man with a type 2 lesion in the upper thoracic esophagus; clinical stage was T3 or partial T4N1M0. After chemoradiotherapy the tumor and the lymph nodes become smaller, and subtotal esophagectomy was performed. Patient 2 was a 66-year-old man with a protruding lesion in the lower thoracic esophagus. Preoperative chemoradiotherapy was administered, and he had a partial response. However, surgery was postponed because of pneumonia; 11 months later, tumor enl...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Indications, techniques, and outcomes of endoscopic submucosal dissection for esophageal squamous cell carcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Endoscopic submucosal dissection (ESD) has gradually gained acceptance as one of the standard treatments for esophageal squamous cell carcinoma in Japan. Principal indications are little likelihood of nodal metastasis and having technical resectability. All lesions with preoperative diagnosis of high-grade intraepithelial neoplasms, including carcinomas in situ (T1a-EP), carcinomas invading the lamina propria (T1a-LPM), and some with preoperative diagnosis of carcinomas invading the muscularis mucosa (T1a-MM) and minute submucosal invasion (T1b-SM1), may become candidates for ESD, considering the su...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

GP73 contributes to the sensitivity of cisplatin in esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions GP73 is a candidate gene in esophageal cancer that may be the target of future molecular-targeted therapy in combination with CDDP. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-009-0201-4Authors Takeyasu Katada, Nagoya City University Graduate School of Medical Science, Oncology, Immunology and Surgery 1 Kawasumi, Mizuho-cho, Mizuho-ku Nagoya 467-8601 JapanHideyuki Ishiguro, Nagoya City University Graduate School of Medical Science, Oncology, Immunology and Surgery 1 Kawasumi, Mizuho-cho, Mizuho-ku Nagoya 467-8601 JapanMasahiro Kimura, Nagoya City University Gra...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Is postoperative early enteral nutrition with regular or disease-specific enteral formula really beneficial in patients undergoing esophagectomy?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Although recent studies have shown that early enteral nutrition (EEN) has certain advantages over parenteral nutrition for preventing postoperative complications, few previous studies have examined the effects of enteral nutrition in patients undergoing esophagectomy. Here we review the effects of EEN with regular polymeric or other disease-specific enteral formulas in patients undergoing esophagectomy. Previously reported data suggest that nutritional management with early enteral feeding may be beneficial and that an appropriate selection of specific enteral formula enriched with disease-specific ...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Multiple lesions of adenocarcinoma with extensive dysplasia in long-segment Barrett’s esophagus treated with thoracoscopic surgery: a case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this report, we describe a Japanese case of multiple lesions of adenocarcinoma in long-segment Barrett’s esophagus, resected by thoracoscopic surgery. Our experience indicates that thoracoscopic esophagectomy could be one of the treatment options for multiple malignant or extensive precancerous lesions in long-segment Barrett’s esophagus. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10388-009-0199-7Authors Takeshi Iwaya, Iwate Medical University School of Medicine Department of Surgery 19-1 Uchimaru Morioka 020-8505 JapanYusuke Kimura, Iwate Medical University School of Medicine Department of ...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Complete regression of advanced esophageal cancer with abdominal bulky lymph node metastasis treated by concurrent chemoradiotherapy using docetaxel, cisplatin, and 5-fluorouracilEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In an attempt to improve survival of patients with locally advanced esophageal cancer, chemoradiotherapy consisting of cisplatin, 5-fluorouracil (5-FU), and irradiation has recently been used. For such patients, concurrent chemoradiotherapy using docetaxel in combination with cisplatin and 5-FU has been introduced and is under evaluation. We herein report an esophageal cancer patient with concomitant distant lymph node metastasis in whom a complete response was achieved by chemoradiation therapy. A 46-year-old man was diagnosed as having stage IV A esophageal cancer with synchronous bulky metastasis...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Management of esophageal foreign bodies: experience of 90 casesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The majority of esophageal foreign bodies were successfully removed nonendoscopically in pediatric patients and endoscopically in adult patients. Endoscopic removal under topical pharyngeal anesthesia may not be indicated for patients who have swallowed large dental prostheses. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-009-0190-3Authors Tatsuya Miyazaki, Saitama Medical University Department of Digestive Tract and General Surgery, Saitama Medical Center 1981 Tsujido-Machi, Kamoda Kawagoe, Saitama 350-8550 JapanNaoko Hokama, Saitama Medical University Departmen...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Esophageal stenosis caused by T0 lung cancer with lymph node metastasis: a case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract T0 lung cancer is an intrathoracic tumor with an unknown primary site that is diagnosed as originating from lung tissue by histological examination. A 52-year-old man presented with esophageal stenosis. Esophagogastroscopy revealed severe stenosis of the upper esophagus with normal mucosa. Chest computed tomography showed a mass adjacent to the azygos vein and right main bronchus, and another mass in the posterior mediastinum that compressed the right main bronchus. Initially, we diagnosed esophageal cancer with mediastinal lymph node metastasis. The patient died 24 months after starting chemotherap...
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Role of FDG-PET in the multimodality treatment of esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Case AtlasDOI 10.1007/s10388-009-0192-1 Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 6 Journal Issue Volume 6, Number 3 / September, 2009 (Source: Esophagus)
Source: Esophagus - September 15, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Rapid-growth carcinosarcoma of the esophagus arising from 0-IIc squamous cell carcinoma after definitive chemoradiotherapy: a case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A case of carcinosarcoma arising from the area of intraepithelial spread of relapsed esophageal squamous cell carcinoma (SCC) after definitive chemoradiotherapy (CRT) is reported herein. A 71-year-old man was referred to our hospital because of a superficial esophageal carcinoma. Definitive CRT was performed because the patient refused surgical treatment. Complete response was recognized after CRT, but tumor relapse was diagnosed 3 months later. The relapsed tumor initially revealed a minimal depression with a small white nodule. This nodule developed to a sessile elevated mass after 1 month and fin...
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

A case of a gastrobronchial fistula after esophageal reconstruction successfully closed with an intercostal muscle flapEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 63-year-old man with esophageal cancer underwent a subtotal esophagectomy via the thoracolaparotomy approach. Two years after the operation, a gastrobronchial fistula unexpectedly occurred in the right bronchus. After admission, medication including omeprazole and nutritional support administered through an enteral tube improved his general condition, and the gastrobronchial fistula was successfully closed with the seventh intercostal muscle flap. After the operation, sputa were aspirated with a bronchofiberscope through a tracheal incision rather than blindly with a catheter. He was in good condi...
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Comprehensive Registry of Esophageal Cancer in Japan, 2001Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Special ArticleDOI 10.1007/s10388-009-0189-9Authors Soji Ozawa, Japan Esophageal Society Sun-city Inohana B, 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanYuji Tachimori, Japan Esophageal Society Sun-city Inohana B, 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanHideo Baba, Japan Esophageal Society Sun-city Inohana B, 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanHisahiro Matsubara, Japan Esophageal Society Sun-city Inohana B, 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanKei Muro, Japan Esophageal Society Sun-city Inohana B, 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanHodaka Numasaki, Japan Esop...
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Assessment of neoadjuvant chemotherapy for patients with advanced squamous cell carcinoma of the esophagusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These results suggest that chemotherapy improves prognosis of responders significantly more than those who show downstaged pathological stage. However, the chemotherapy does not give any clinical benefit for non-responders. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-009-0188-xAuthors Masahiko Yano, Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Surgery 1-3-3 Nakamichi, Higashinari-ku Osaka 537-8511 JapanMasaaki Motoori, Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Surgery 1-3-3 Nakamichi, Higashinari-ku Osa...
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Japanese classification of esophageal cancer, tenth edition: parts II and IIIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Special ArticleDOI 10.1007/s10388-009-0193-0Authors Japan Esophageal Society, Sun-city Inohana B, 3-2-4 Inohana, Chuo-ku Chiba 260-0856 Japan Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 6 Journal Issue Volume 6, Number 2 / June, 2009 (Source: Esophagus)
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Skeletal muscle metastasis from esophageal cancer: a report of two cases and a review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes two cases of skeletal muscle metastasis from esophageal cancer as the first distant metastasis. Case 1, a 58-year-old man with stage IVa upper thoracic esophageal squamous cell carcinoma (SqCC), underwent chemoradiotherapy (CRT) and a subtotal esophagectomy with a three-field lymph node dissection. After the operation, he complained of a painful mass in his forearm, which was diagnosed to be metastatic SqCC by a biopsy. Local radiation therapy and systemic chemotherapy were performed, but he died 7 months after the first CRT. Case 2, a 61-year-old woman with stage IVa middle thoracic SqCC, underw...
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Malignant acanthosis nigricans with esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 62-year-old woman was referred to our hospital with presenting pigmentation and/or dermal thickening in the nucha, face, axilla, abdomen, and hands. She also presented a history of weight loss of 4 kg during the previous 3 months. She was pathologically diagnosed as having acanthosis nigricans by skin biopsy. She subsequently underwent 18F-FDG-PET, CT, and upper gastrointestinal endoscopy, and then was diagnosed as having malignant acanthosis nigricans with squamous cell carcinoma in the esophagus at the clinical stage of T3, N0, M0, stage IIA in the UICC stage classification. She underwent subtot...
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Treatment process and tumor marker of esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Case AtlasDOI 10.1007/s10388-009-0191-2 Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 6 Journal Issue Volume 6, Number 2 / June, 2009 (Source: Esophagus)
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Mediastinal microdialysis: early diagnosis of anastomotic leakage after resection for esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The aim of the present study was to evaluate the safety of mediastinal microdialysis and its efficacy regarding the early diagnosis of anastomotic leakage after gastroesophageal resection for esophageal cancer. Eight consecutive patients were included; one patient was excluded for reasons of catheter malfunction. The tip of the mediastinal microdialysis catheter was placed close to the anastomosis and held by a 4-0 absorbable suture. A subcutaneous microdialysis catheter placed in the pectoral region served as a reference. Samples collected every 4 h in the first 8 postoperative days were analyzed f...
Source: Esophagus - March 18, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Lymph node dissection with cervical approach as a salvage surgery for locoregional failure after definitive chemoradiotherapy in a patient with recurrent esophageal carcinoma: report of a caseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Salvage surgery is one important therapeutic option after locoregional failure of definitive chemoradiotherapy (dCRT) in patients with advanced or recurrent esophageal carcinoma. We have performed cervical lymph node dissection as a salvage surgery after chemoradiotherapy in a patient with recurrent esophageal carcinoma. A 54-year-old Japanese man was admitted to our hospital because of multiple lymph node metastases after endoscopic submucosal dissection (ESD) for early-stage esophageal carcinoma. The patient underwent a circumferential ESD of early-stage esophageal carcinoma in another hospital. T...
Source: Esophagus - March 18, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Japanese Classification of Esophageal Cancer, tenth edition: part IEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Special ArticleDOI 10.1007/s10388-009-0169-0Authors Japan Esophageal Society, Sun-city Inohana B 3-2-4 Inohana, Chuo-ku Chiba 260-0856 Japan Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 6 Journal Issue Volume 6, Number 1 / March, 2009 (Source: Esophagus)
Source: Esophagus - March 18, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Comprehensive Registry of Esophageal Cancer in Japan, 2000Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Special ArticleDOI 10.1007/s10388-009-0185-0Authors Hiroko Ide, Sun-city Inohana B Japan Esophageal Society 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanSoji Ozawa, Sun-city Inohana B Japan Esophageal Society 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanHisahiro Matsubara, Sun-city Inohana B Japan Esophageal Society 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanTakao Saito, Sun-city Inohana B Japan Esophageal Society 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanMasayuki Shinoda, Sun-city Inohana B Japan Esophageal Society 3-2-4 Inohana, Chuo-ku Chiba 260-0856 JapanYuji Tachimori, Sun-city In...
Source: Esophagus - March 18, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Giant gastrointestinal stromal tumor in the esophagusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of a 74-year-old woman with an esophageal gastrointestinal stromal tumor (GIST). Endoscopic examination suggested a submucosal tumor in the middle-lower thoracic esophagus. Computed tomography showed a solid mass 95 × 56 × 44 mm in size, suggesting an esophageal mesenchymal tumor. Endoscopic ultrasonography-guided fine-needle aspiration biopsy was positive for c-kit and CD34, and negative for both S-100 and desmin, on immunohistochemical examination, confirming this to be a GIST. The patient underwent transthoracic esophagectomy with esophageal reconstruction using a gastric tube through the subcutan...
Source: Esophagus - March 18, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Superficial esophageal squamous cell carcinoma type 0-IIb+IIc (MM): a case atlasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Case AtlasDOI 10.1007/s10388-009-0184-1Authors Tsuneo Oyama, Saku Central Hospital Department of Gastroenterology 197 Usuda, Saku Nagano 384-0301 JapanYoko Kitamura, Saku Central Hospital Department of Gastroenterology 197 Usuda, Saku Nagano 384-0301 JapanAkiko Takahashi, Saku Central Hospital Department of Gastroenterology 197 Usuda, Saku Nagano 384-0301 JapanAkihisa Tomori, Saku Central Hospital Department of Gastroenterology 197 Usuda, Saku Nagano 384-0301 JapanKinich Hotta, Saku Central Hospital Department of Gastroenterology 197 Usuda, Saku Nagano 384-0301 Japan Journal ...
Source: Esophagus - March 18, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

Severe benign esophageal stricture following postoperative emesisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract An 80-year-old man presented with dysphagia after surgery for a hepatic tumor. In the postoperative period, he suffered from emesis and thereafter experienced dysphagia when taking a solid meal. The cause of his dysphagia was a benign lower esophageal stricture that had not been detected during preoperative examinations. Conservative treatment involving balloon dilatation was not effective, and the patient finally underwent a lower esophagectomy with reconstruction of the jejunum interposition from a left thoraco-abdominal approach. Based on his clinical manifestations, pathological findings, and pu...
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Surgical and nonsurgical management of perforation complicating endoscopic submucosal dissection of esophageal cancer: report of three casesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Perforation of the esophagus during endoscopic therapy is a severe complicati1on. Nonetheless, almost all perforations made during endoscopic submucosal dissection can be treated conservatively because their early diagnosis, the good condition of the patient, and their small size enables them to be closed with endoscopic clips. If inflammation around the esophagus progresses to mediastinitis, however, surgical management such as debridement and drainage should be applied without delay. Here we report three cases of esophageal perforation during endoscopic submucosal dissection that were successfully...
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Eosinophilic esophagitis: a rapidly emerging diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions EoE represents a immune-mediated disease of undetermined pathogenesis. Natural history studies as well as prospective therapeutic trials will be critical to defining future treatment strategies. Content Type Journal ArticleCategory Congress Report: Invited LectureDOI 10.1007/s10388-008-0172-xAuthors Alex Straumann, Kantonsspital Olten Department of Gastroenterology Roemerstrasse 7 4600 Olten Switzerland Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 5 Journal Issue Volume 5, Number 4 / December, 2008 (Source: Esophagus)
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Gastric gastrointestinal stromal tumor with synchronous metastasis to the esophagus: case report and review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a patient with synchronous gastrointestinal stromal tumors (GISTs) of the stomach and esophagus. The gastric GIST was larger than that in the esophagus, and no direct connection between the two lesions was seen microscopically. Based on molecular analysis, both lesions had the same c-kit mutation on exon 11, with deletion of codon 557–558. Analysis of normal gastric tissue showed no mutations. The gastric GIST was the primary lesion, and the esophageal tumor was thought to suggest a hematogenous metastasis. A liver metastasis in S6 appeared 6 months after surgery. Imatinib mesylate has been an effective tre...
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Fabulous contributions of Japanese doctors to relevant gastrointestinal, especially esophageal, pathology in the United States as well as areas of contentionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract There are innumerable contributions of Japanese doctors, especially Japanese pathologists, to the practice of modern gastrointestinal pathology. Among these are the basic descriptions and definitions of the most important gastric polyps, the identification of the duplicated muscularis mucosae in Barrett’s esophagus, the discovery of the minute or seedling leiomyomas in both muscularis mucosae and propria, and the first recognition of the importance of the c-kit gene and its protein product in the evolution of gastrointestinal stromal tumors and in defining the cells that make up these tumors. Ther...
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

One American pathologist’s view of the diagnosis of Barrett’s mucosa and its neoplastic complications: we do not always have to agree, but we need to respect our differencesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract In the United States, Barrett’s mucosa is defined as having an endoscopic change that looks like columnar mucosa in the lower esophagus and goblet cells in a biopsy from that endoscopic abnormality. This is not a universally accepted definition. In both Japan and the United Kingdom, the endoscopic change is still required, but any columnar mucosa, whether or not it has goblet cells, is adequate for the Barrett’s diagnosis. This difference of opinion probably does not affect patient care, because the American definition seems to work well from a clinical standpoint in the United States, while the...
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Aggressive progression of granulocyte colony-stimulating factor producing squamous cell carcinoma of the esophagus: case report and literature reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of a 69-year-old man who was diagnosed to have granulocyte colony-stimulating factor (G-CSF)-producing esophageal squamous cell carcinoma, based on a histological examination of endoscopic biopsy specimens. A high serum level of leukocytes and G-CSF was noted. Moreover, immunohistochemical examination revealed that the tumor cells were positive for antibodies against G-CSF. Palliative radiation therapy was performed because of existing distant metastasis at the time of presentation, and the patient died of tumor progression 7 months after the initial diagnosis. To the best of our knowledge, only five c...
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Summaries from The 62nd Annual Meetings of the Japan Esophageal Society June 21–22, 2008, TokyoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Congress Report: SummariesDOI 10.1007/s10388-008-0170-z Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 5 Journal Issue Volume 5, Number 4 / December, 2008 (Source: Esophagus)
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Multidisciplinary treatment of uncommon types of esophageal tumorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Case AtlasDOI 10.1007/s10388-008-0168-6 Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 5 Journal Issue Volume 5, Number 4 / December, 2008 (Source: Esophagus)
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Esophagoscopy-guided thoracoscopic resection of large epiphrenic esophageal diverticulumEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A diverticulum in the lower third of the esophagus is rare. A 62-year-old woman presented with symptoms of dysphagia and regurgitation associated with recurrent aspiration. Endoscopic examination disclosed a large epiphrenic diverticulum, for which esophagoscopy-guided thoracoscopic surgery was performed. The postoperative course was uneventful. It is proposed that this method could be a possible alternative to the standard classical thoracotomy approach for a large epiphrenic diverticulum of the esophagus. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10388-008-0176-6Authors Masa...
Source: Esophagus - December 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Surgical attempts to avoid anastomotic leaks and reduce reflux esophagitis following esophagectomy for cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our surgical attempts to avoid leaks of esophagogastrostomy were entirely successful. An intrathoracic anastomosis combined with an antireflux procedure was not advantageous for the incidence of reflux esophagitis compared to cervical anastomosis, but it minimized the effects of anastomotic height on the development of reflux esophagitis. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-008-0165-9Authors Satoshi Aiko, National Defense Medical College Department of Surgery II 3-2 Namiki, Tokorozawa Saitama 359-8513 JapanYutaka Yoshizumi, National Defense Medical Colle...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Therapeutic management of elderly patients with esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Elderly patients obtained similar therapeutic benefits from esophagectomy as did nonelderly patients through careful management of comorbid disease and good perioperative care. Also, nonsurgical treatment is a useful treatment option for elderly patients. A well-designed randomized trial, of surgical versus nonsurgical treatment, should be conducted in the elderly to clarify this concern. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-008-0159-7Authors Ryo Takagawa, Yokohama City University Department of Surgery, Gastroenterological Center 4-57 Urafune-cho, Minami...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Guidelines for diagnosis and treatment of carcinoma of the esophagusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Special ArticleDOI 10.1007/s10388-008-0158-8Authors Hiroyuki KuwanoYasumasa NishimuraAtsushi OhtsuHiroyuki KatoYuko KitagawaSetsuo TamaiYasushi TohHisahiro Matsubara Journal EsophagusOnline ISSN 1612-9067Print ISSN 1612-9059 Journal Volume Volume 5 Journal Issue Volume 5, Number 3 / September, 2008 (Source: Esophagus)
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Spontaneous esophageal rupture responding to simple suture closure, drainage, and percutaneous endoscopic gastrostomy (PEG): case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Spontaneous esophageal rupture is a rare disease, and the diagnosis and treatment have not been fully established. Herein we present a 55-year-old man with spontaneous esophageal rupture who was successfully treated using simple suture closure, drainage, and intraoperative percutaneous endoscopic gastrostomy. He was brought to the emergency room after vomiting gastric contents and blood and then experiencing chest pain. On admission, vital signs were normal. Emergency endoscopy was performed for hemostasis, and spontaneous esophageal rupture was diagnosed. As chest computed tomography suggested intr...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

A case of thoracoscopically resected benign esophageal schwannoma with high uptake on FDG-PETEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a rare case of esophageal schwannoma with high uptake of radiotracer on [18F]fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET). A 37-year-old woman underwent surgery for sarcoma of the uterus and received general PET examination for postoperative follow-up, which revealed high uptake at the thoracic esophagus. Esophagography, esophageal endoscopy, endoscopic ultrasonography, and computed tomography (CT) scan confirmed a submucosal tumor, about 20 mm in diameter, in the right wall of the upper thoracic esophagus. We performed thoracoscopic enucleation with the preoperative diagnosis of esophageal...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Carcinosarcoma of the esophagus producing granulocyte-colony stimulating factor: report of a caseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 51-year-old man was admitted to the hospital for dysphagia, pyrexia, and leukocytosis. The serum level of granulocyte-colony stimulating factor (G-CSF) was elevated. Barium esophagography and endoscopy revealed a polypoid tumor in the middle portion of the esophagus. After an esophagectomy, the leukocyte count and serum G-CSF level normalized. The pathological diagnosis was carcinosarcoma of the esophagus with two components: namely, squamous cell carcinoma and sarcoma. Moreover, cancer cells were positive for G-CSF antibody. These findings confirmed that the esophageal carcinosarcoma in this case...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Two resected cases of esophageal leiomyoma diagnosed with preoperative endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report herein on two resected cases of esophageal leiomyoma preoperatively diagnosed accurately with endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB). The first patient, a 34-year-old man, had complained of dysphagia. Following EUS-FNAB, the pathological diagnosis was leiomyoma. Esophagectomy and reconstruction with a gastric tube were performed because the tumor had almost completely encircled the esophageal wall. The second patient, a 60-year-old woman, had complained of dysphagia. Following EUS-FNAB, the pathological diagnosis was leiomyoma. Enucleation of the tumor was performed because the...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Metastatic hypopharyngeal and esophageal cancer to a percutaneous endoscopic gastrostomy siteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The patient was a 63-year-old man who underwent percutaneous endoscopic gastrostomy (PEG) for nutritional management while undergoing radiochemotherapy for hypopharyngeal and esophageal cancer. At about 6 months after PEG, redness and swelling were seen around the gastrostomy site, and pathological testing confirmed the same poorly differentiated squamous cell carcinoma as the hypopharyngeal and esophageal cancer. The tumor caused symptoms associated with buried bumper syndrome to increase significantly. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10388-008-0160-1Authors Naruo ...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Basaloid squamous carcinoma of the esophagus developed from achalasia: report of a caseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 57-year-old man, who had been diagnosed as having flask type, grade II achalasia of the esophagus at the age of 26, underwent Heller’s esophagomyectomy in a nearby hospital in 1971. A type 0-Is lesion measuring 2 cm in size was found on the middle thoracic esophagus in September 2002. A protruding tumor with a central depression, not stained with iodine, was detected by endoscopic examination. Standard subtotal esophagectomy with three-field lymph node dissection was performed. By histopathological examination, the esophageal lesion was classified as basaloid squamous carcinoma, extending to the...
Source: Esophagus - September 18, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Long-surviving case of advanced esophageal small cell carcinoma with a multidisciplinary treatment approachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 64-year-old man presented with dysphagia and heartburn. Upper gastrointestinal endoscopy showed an irregular type 2 tumor of the lower esophagus. Histological examination of the biopsy specimen revealed undifferentiated carcinoma, small cell type. Subtotal esophagectomy was performed. Two months after the initial surgery, an intradural extramedullary metastasis was found, and tumorectomy was performed. Eight months after the initial surgery, lymph node metastases were found, and alternate-week administration of CPT-11 was begun. Thirteen months after the initial surgery, an oropharyngeal metastasi...
Source: Esophagus - July 2, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus April 2007 edition: part I Edited by the Japan Esophageal SocietyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Special ArticleDOI 10.1007/s10388-008-0151-2Authors Hiroyuki Kuwano, Gunma University Graduate School of Medicine Department of General Surgical Science 3-39-22 Showa-machi Maebashi 371-8511 JapanYasumasa Nishimura, Kinki University School of Medicine Department of Radiology Osakasayama JapanAtsushi Ohtsu, National Cancer Center Hospital East Division of Internal Medicine Kashiwa JapanHiroyuki Kato, Gunma University Graduate School of Medicine Department of General Surgical Science 3-39-22 Showa-machi Maebashi 371-8511 JapanYuko Kitagawa, Keio University Department of Surgery, Schoo...
Source: Esophagus - July 2, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Setting of the candidate exposure conditions in an individualized tumor response testing (ITRT) toward an individual chemotherapy for esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Although the study failed to compare in vitro results with clinical outcomes in measurable lesions, and the practical usefulness and applicability of the technique remain to be demonstrated, CD-DST might be a useful tool in selecting optimal chemotherapeutic agents. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-008-0154-zAuthors Toshio Takayama, Juntendo University School of Medicine Department of Gastroenterological Surgery 2-1-1 Hongo, Bunkyo-ku Tokyo 113-8421 JapanMasahiko Tsurumaru, Juntendo University School of Medicine Department of Gastroenterological Surge...
Source: Esophagus - July 2, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals

Excess visceral fat accumulation is a risk factor for postoperative systemic inflammatory response syndrome in patients with esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Patients with visceral fat area of more than 100 cm2 are at high risk for prolonged postoperative SIRS. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s10388-008-0150-3Authors Koji Tanaka, Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Surgery 1-3-3 Nakamichi, Higashinari-ku Osaka 537-8511 JapanMasahiko Yano, Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Surgery 1-3-3 Nakamichi, Higashinari-ku Osaka 537-8511 JapanMasaaki Motoori, Osaka Medical Center for Cancer and Cardiovascular Diseases Department of Surgery 1-3-3 Nak...
Source: Esophagus - July 2, 2008 Category: Gastroenterology Tags: Esophagus Source Type: journals