European Heart Journal
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Coronary sequelae of mitral stenosis
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Wiedemann, S., Stolte, D., Simonis, G. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Resting heart rate and excessive heart rate increase during pre-exercise mental stress: which one predicts mortality? Reply
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Jouven, X. Tags: LETTERS TO THE EDITOR Source Type: journals
Resting heart rate and excessive heart rate increase during pre-exercise mental stress: which one predicts mortality?
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Fourlas, C. A. Tags: LETTERS TO THE EDITOR Source Type: journals
Abnormal left ventricular relaxation in patients with long QT syndrome: reply
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Haugaa, K. H., Edvardsen, T., Leren, T. P., Smiseth, O. A., Amlie, J. P. Tags: LETTERS TO THE EDITOR Source Type: journals
Abnormal left ventricular relaxation in patients with long QT syndrome
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Belardinelli, L., Dhalla, A., Shryock, J. Tags: LETTERS TO THE EDITOR Source Type: journals
C-reactive protein: not only a marker but also a mediator of myocardial damage following acute myocardial infarction
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Celik, T. Tags: LETTERS TO THE EDITOR Source Type: journals
Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: The Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Society of Cardiology (ESC) and endorsed by the European Society of Anaesthesiology (ESA)
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Authors/Task Force Members, Poldermans, D., Bax, J. J., Boersma, E., De Hert, S., Eeckhout, E., Fowkes, G., Gorenek, B., Hennerici, M. G., Iung, B., Kelm, M., Kjeldsen, K. P., Kristensen, S. D., Lopez-Sendon, J., Pelosi, P., Philippe, F., Pierard, L., Pon Tags: ESC GUIDELINES Source Type: journals
Severe coronary spasm occasionally detected by coronary computed tomography
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Ito, K., Ogawa, T., Yoshimura, M. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
A simplified biventricular defibrillator with fixed long detection intervals reduces implantable cardioverter defibrillator (ICD) interventions and heart failure hospitalizations in patients with non-ischaemic cardiomyopathy implanted for primary prevention: the RELEVANT [Role of long dEtection window programming in patients with LEft VentriculAr dysfunction, Non-ischemic eTiology in primary prevention treated with a biventricular ICD] study
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Conclusion
A simplified CRT-D device with fixed long detection reduced overall ICD therapy burden and HF hospitalizations without entailing any additional adverse events in primary prevention non-ischaemic HF patients. (Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Gasparini, M., Menozzi, C., Proclemer, A., Landolina, M., Iacopino, S., Carboni, A., Lombardo, E., Regoli, F., Biffi, M., Burrone, V., Denaro, A., Boriani, G. Tags: Arrhythmia/electrophysiology Source Type: journals
Growth differentiation factor-15 predicts mortality and morbidity after cardiac resynchronization therapy
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Conclusion
Pre-implant GDF-15 is a strong predictor of mortality and morbidity after CRT, independent of NT pro-BNP. The predictive value of these analytes is enhanced by combined measurement. (Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Foley, P. W.X., Stegemann, B., Ng, K., Ramachandran, S., Proudler, A., Frenneaux, M. P., Ng, L. L., Leyva, F. Tags: Heart failure/cardiomyopathy Source Type: journals
Association between type II secretory phospholipase A2 plasma concentrations and activity and cardiovascular events in patients with coronary heart disease
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Conclusion
Secretory phospholipase A2 mass and activity appear to be predictive of secondary CVD events in patients with CHD. (Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Koenig, W., Vossen, C. Y., Mallat, Z., Brenner, H., Benessiano, J., Rothenbacher, D. Tags: Coronary heart disease Source Type: journals
Effect of irbesartan and enalapril in non-ST elevation acute coronary syndrome: results of the randomized, double-blind ARCHIPELAGO study
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Conclusion
In patients with NSTEACS, inflammatory markers decreased over time in both treatment arms, with no differences between irbesartan and enalapril. (Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Montalescot, G., Drexler, H., Gallo, R., Pearson, T., Thoenes, M., Bhatt, D. L. Tags: Coronary heart disease Source Type: journals
Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathy
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Conclusion
Together these data demonstrate that autologous MSCs can be safely delivered in an adult heart failure model, producing substantial structural and functional reverse remodelling. These findings demonstrate the safety and efficacy of autologous MSC therapy and support clinical trials of MSC therapy in patients with chronic ischaemic cardiomyopathy. (Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Schuleri, K. H., Feigenbaum, G. S., Centola, M., Weiss, E. S., Zimmet, J. M., Turney, J., Kellner, J., Zviman, M. M., Hatzistergos, K. E., Detrick, B., Conte, J. V., McNiece, I., Steenbergen, C., Lardo, A. C., Hare, J. M. Tags: Coronary heart disease Source Type: journals
Severe right bivalvular carcinoid heart disease
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Jadidi, A. S., Didier, D., Karaca, S., Muller, H. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Stent thrombosis after drug-eluting stent implantation: incidence, timing, and relation to discontinuation of clopidogrel therapy over a 4-year period
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Conclusion
The 4 year incidence of ST after DES implantation is low. A relevant number of ST occur early after discontinuation of clopidogrel therapy. The dependence of ST on discontinuation of clopidogrel therapy seems to be mostly confined to the first 6 months after DES implantation. However, specifically designed randomized studies are required to establish the optimal length of clopidogrel therapy after DES implantation. (Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Schulz, S., Schuster, T., Mehilli, J., Byrne, R. A., Ellert, J., Massberg, S., Goedel, J., Bruskina, O., Ulm, K., Schomig, A., Kastrati, A. Tags: Coronary heart disease Source Type: journals
Primary cardiac T-cell lymphoma in a child
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Patel, J., Sheppard, M. N. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials
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Conclusion
This meta-analysis shows a significant relationship between benefits in mortality from Gp IIb-IIIa inhibitors and patient's risk profile. Thus, Gp IIb-IIIa inhibitors should be strongly considered among high-risk patients. (Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: De Luca, G., Navarese, E., Marino, P. Tags: Coronary heart disease Source Type: journals
Carotid artery stenting vs. endarterectomy
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Randomized clinical trials have demonstrated that carotid endarterectomy (CEA) is superior to medical management for stroke prevention in patients with symptomatic and, to a lesser degree, asymptomatic internal carotid artery stenosis. However, large-scale registries have shown that the adverse event rates following CEA are commonly higher than observed in the trials. In the last decade, carotid artery stenting (CAS) has emerged as a less invasive alternative to surgery. In order to address the efficacy of CAS, we performed a meta-analysis of 10 randomized trials comparing CAS with CEA in 4648 mainly symptomatic patients. ...
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Roffi, M., Mukherjee, D., Clair, D. G. Tags: Controversies in cardiovascular medicine series Source Type: journals
Not too late, not too fast!!
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Leclercq, C., Daubert, C., Mabo, P. Tags: EDITORIALS Source Type: journals
Stent thrombosis: who's guilty?
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Authors: Montalescot, G., Hulot, J.-S., Collet, J.-P. Tags: EDITORIALS Source Type: journals
EHJ's People's corner
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Tags: CardioPulse Source Type: journals
CardioPulse Articles
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(Source: European Heart Journal)
Source: European Heart Journal - November 14, 2009 Category: Cardiology Tags: CardioPulse Source Type: journals
Guidelines for the diagnosis and management of syncope (version 2009): The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC)
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Developed in collaboration with, European Heart Rhythm Association (EHRA), Heart Failure Association (HFA), and Heart Rhythm Society (HRS), Endorsed by the following societies, European Society of Emergency Medicine (EuSEM), European Federation of Interna Tags: ESC GUIDELINES Source Type: journals
Percutaneous treatment of a giant right coronary artery pseudoaneurysm in Adamantiades-Behcet's syndrome
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Kasapis, C., Grossman, P. M., Chetcuti, S. J. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Incremental prognostic value of multi-slice computed tomography coronary angiography over coronary artery calcium scoring in patients with suspected coronary artery disease
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Conclusion
MSCTA provides additional information to CS regarding stenosis severity and plaque composition. This additional information was shown to translate into incremental prognostic value over CS. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: van Werkhoven, J. M., Schuijf, J. D., Gaemperli, O., Jukema, J. W., Kroft, L. J., Boersma, E., Pazhenkottil, A., Valenta, I., Pundziute, G., de Roos, A., van der Wall, E. E., Kaufmann, P. A., Bax, J. J. Tags: Imaging Source Type: journals
Prevalence and outcome of newly detected diabetes in patients who undergo percutaneous coronary intervention
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Conclusion
The prevalence of diabetes in patients who underwent PCI was very high (45%), 35% of which was patients with newly detected diabetes. In our series newly detected diabetes was not an independent predictor of outcome at 12 months. Nevertheless, this finding requires independent confirmation in other series to draw general conclusions on the whole spectrum of percutaneous interventions. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: de la Hera, J. M., Delgado, E., Hernandez, E., Garcia-Ruiz, J. M., Vegas, J. M., Avanzas, P., Lozano, I., Barriales-Villa, R., Hevia, S., Martin, J. S., Alvarez, F., Moris, C. Tags: Prevention and epidemiology Source Type: journals
Magnetic resonance assessment of fibrosis in systemic right ventricle after atrial switch procedure
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Ladouceur, M., Bruneval, P., Mousseaux, E. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Arrhythmias and increased neuro-endocrine stress response during physicians' night shifts: a randomized cross-over trial
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Conclusion
Our results highlight the association of OCD with an increased risk profile for cardiovascular disease. In addition to the acute effects observed, frequent night-calls over a longer period possibly elicit sustained alterations in cardiovascular homeostasis. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Rauchenzauner, M., Ernst, F., Hintringer, F., Ulmer, H., Ebenbichler, C. F., Kasseroler, M.-T., Joannidis, M. Tags: Arrhythmia/electrophysiology Source Type: journals
Exercise-induced ventricular arrhythmias and risk of sudden cardiac death in patients with hypertrophic cardiomyopathy
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Conclusion
Ventricular arrhythmia during symptom limited exercise is rare in patients with hypertrophic cardiomyopathy, but is associated with an increased risk of sudden cardiac death. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Gimeno, J. R., Tome-Esteban, M., Lofiego, C., Hurtado, J., Pantazis, A., Mist, B., Lambiase, P., McKenna, W. J., Elliott, P. M. Tags: Heart failure/cardiomyopathy Source Type: journals
Frightening ST-segment elevation
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Martins, R. P., Baruteau, A.-E., Daubert, J.-C. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Disease penetrance and risk stratification for sudden cardiac death in asymptomatic hypertrophic cardiomyopathy mutation carriers
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Conclusion
Hypertrophic cardiomyopathy was diagnosed in 41% of carriers. Disease penetrance was age dependent, warranting repeated cardiologic evaluation. The MYBPC3 mutation carriers were affected at higher age than MYH7 mutation carriers. Risk factors for SCD were present in carriers with and without HCM. Follow-up studies are necessary to evaluate the effectiveness of risk stratification for SCD in this population. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Michels, M., Soliman, O. I.I., Phefferkorn, J., Hoedemaekers, Y. M., Kofflard, M. J., Dooijes, D., Majoor-Krakauer, D., Ten Cate, F. J. Tags: Heart failure/cardiomyopathy Source Type: journals
The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease: a report from APPROACH
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Conclusion
A paradoxical association between BMI and survival exists in patients with established CAD irrespective of treatment strategy. Patients with obesity may be presenting earlier and receiving more aggressive treatment compared with those with normal BMI. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Oreopoulos, A., McAlister, F. A., Kalantar-Zadeh, K., Padwal, R., Ezekowitz, J. A., Sharma, A. M., Kovesdy, C. P., Fonarow, G. C., Norris, C. M. Tags: Coronary heart disease Source Type: journals
Transfusion and mortality in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention
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Conclusion
Transfusion is associated with 90-day mortality in acute myocardial infarction treated with primary percutaneous coronary intervention. Although transfusion may be causally related to mortality, it is likely that at least part of the association is due to confounding. This association illustrates the complex relationship between transfusion, bleeding, and mortality and underscores the need for further research to understand the relationship between transfusion and clinical outcomes. (Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Jolic{oelig}ur, E. M., O'Neill, W. W., Hellkamp, A., Hamm, C. W., Holmes, D. R., Al-Khalidi, H. R., Patel, M. R., Van de Werf, F. J., Pieper, K., Armstrong, P. W., Granger, C. B., for the APEX-AMI Investigators Tags: Coronary heart disease Source Type: journals
Tuberculous pericarditis with constrictive physiology
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Kraen, M., Muller, M., Bjorkman, P. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Imaging of the unstable plaque: how far have we got?
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Rupture of unstable plaques may lead to myocardial infarction or stroke and is the leading cause of morbidity and mortality in western countries. Thus, there is a clear need for identifying these vulnerable plaques before the rupture occurs. Atherosclerotic plaques are a challenging imaging target as they are small and move rapidly, especially in the coronary tree. Many of the currently available imaging tools for clinical use still provide minimal information about the biological characteristics of plaques, because they are limited with respect to spatial and temporal resolution. Moreover, many of these imaging tools are ...
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Matter, C. M., Stuber, M., Nahrendorf, M. Tags: Controversies in cardiovascular medicine series Source Type: journals
Hotline sessions of the 31st European Congress of Cardiology
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Evertz, R., van Bennekom, S., Dirksen, M. T., Verheugt, F. W.A. Tags: ESC REPORT Source Type: journals
Night shift work and the cardiovascular health of medical staff
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Steptoe, A. Tags: EDITORIALS Source Type: journals
Sudden cardiac death risk in hypertrophic cardiomyopathy
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Ommen, S. R., Gersh, B. J. Tags: EDITORIALS Source Type: journals
Is there an acceptable ceiling for bleeding for an antithrombotic drug dose to be tested in a phase 3 trial?
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: White, H. D. Tags: ESC BARCELONA COMMENTARIES Source Type: journals
The RE-LY study: Randomized Evaluation of Long-term anticoagulant therapY: dabigatran vs. warfarin
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Camm, A. J. Tags: ESC BARCELONA COMMENTARIES Source Type: journals
MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy): cardiac resynchronization therapy towards early management of heart failure
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Authors: Breithardt, G. Tags: ESC BARCELONA COMMENTARIES Source Type: journals
CardioPulse Articles
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(Source: European Heart Journal)
Source: European Heart Journal - November 1, 2009 Category: Cardiology Tags: CardioPulse Source Type: journals
Guidelines for the diagnosis and treatment of pulmonary hypertension: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
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(Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: Authors/Task Force Members, Galie, N., Hoeper, M. M., Humbert, M., Torbicki, A., Vachiery, J.-L., Barbera, J. A., Beghetti, M., Corris, P., Gaine, S., Gibbs, J. S., Gomez-Sanchez, M. A., Jondeau, G., Klepetko, W., Opitz, C., Peacock, A., Rubin, L., Zellwe Tags: ESC GUIDELINES Source Type: journals
In vivo histology by cardiovascular magnetic resonance imaging
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(Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: Delnoij, T., van Suylen, R. J., Cleutjens, J. P.M., Schalla, S., Bekkers, S. C.A.M. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
First locus for primary pulmonary vein stenosis maps to chromosome 2q
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Conclusion
Our findings open perspectives for the identification of the genetic cause(s) leading to PVS, which might contribute to elucidate the pathological mechanisms involved in this disorder. (Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: van de Laar, I., Wessels, M., Frohn-Mulder, I., Dalinghaus, M., de Graaf, B., van Tienhoven, M., van der Moer, P., Husen-Ebbinge, M., Lequin, M., Dooijes, D., de Krijger, R., Oostra, B. A., Bertoli-Avella, A. M. Tags: Valvular heart disease Source Type: journals
Increase in end-systolic volume after exercise independently predicts mortality in patients with coronary heart disease: data from the Heart and Soul Study
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Conclusion
End-systolic volume reversal is a novel parameter that independently predicts mortality in patients with CHD undergoing exercise treadmill echocardiography, even after adjustment for a wide range of clinical, echocardiographic, and treadmill exercise variables. Because measurement of ESV is simple, reproducible, and requires no additional imaging views, identification of ESV reversal during exercise echocardiography can provide useful complementary information for risk stratification. (Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: Turakhia, M. P., McManus, D. D., Whooley, M. A., Schiller, N. B. Tags: Coronary heart disease Source Type: journals
Characteristics of heart failure patients associated with good and poor response to cardiac resynchronization therapy: a PROSPECT (Predictors of Response to CRT) sub-analysis
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Conclusion
Sub-analysis of data from PROSPECT showed that gender, aetiology of HF, QRS duration, severity of HF, a history of VT, and the presence of baseline mechanical dyssynchrony influence clinical and/or LV reverse remodelling after CRT. Although integration of information about these characteristics would improve patient selection and counselling for CRT, further randomized controlled trials are necessary prior to changing the current guidelines regarding patient selection for CRT. (Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: van Bommel, R. J., Bax, J. J., Abraham, W. T., Chung, E. S., Pires, L. A., Tavazzi, L., Zimetbaum, P. J., Gerritse, B., Kristiansen, N., Ghio, S. Tags: ESC clinical trial update Source Type: journals
Coronary and vertebral subclavian steal demonstrated by subclavian angiography
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(Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: Acu, B., Firat, M., Onalan, O. Tags: CARDIOVASCULAR FLASHLIGHTS Source Type: journals
Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study
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Conclusion
Valsartan add-on treatment to improve blood pressure control prevented more cardiovascular events than conventional non-ARB treatment in high-risk hypertensive patients in Japan. These benefits cannot be entirely explained by a difference in blood pressure control. (Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: Sawada, T., Yamada, H., Dahlof, B., Matsubara, H., for the KYOTO HEART Study Group Tags: ESC hot line Source Type: journals
The European cardiac resynchronization therapy survey
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Conclusion
This CRT survey provides important information describing current European practice with regard to patient demographics, selection criteria, procedural routines, and status at discharge. These data should be useful for benchmarking individual patient management and national practice against wider experience. (Source: European Heart Journal)
Source: European Heart Journal - October 14, 2009 Category: Cardiology Authors: Dickstein, K., Bogale, N., Priori, S., Auricchio, A., Cleland, J. G., Gitt, A., Limbourg, T., Linde, C., van Veldhuisen, D. J., Brugada, J., on behalf of the Scientific Committee and National Coordinators Tags: ESC hot line Source Type: journals
