Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia
ConclusionFerritin is deregulated in most AML patients likely through inflammation, associated with chemoresistance, and could represent a new therapeutic target. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 28, 2018 Category: Hematology Authors: Sarah Bertoli, Etienne Paubelle, Emilie B érard, Estelle Saland, Xavier Thomas, Suzanne Tavitian, Marie‐Virginie Larcher, François Vergez, Eric Delabesse, Audrey Sarry, Françoise Huguet, Clément Larrue, Claudie Bosc, Thomas Farge, Jean Tags: ORIGINAL ARTICLE Source Type: research

Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group
Conclusionsthe inflammatory state of MF disturbs iron turnover, FID is common and contributes to anaemia development and impairment of QoL. Anaemic MF patients should be screened for FID.This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 25, 2018 Category: Hematology Authors: Gunnar Birgegard, Jan Samuelsson, Erik Ahlstrand, Elisabeth Ejerblad, Christian Enevold, Waleed Ghanima, Hans Hasselbalch, Claus H. Nielsen, H åvar Knutsen, Ole B Pedersen, Anders Sørensen, Björn Andreasson Tags: Original Article Source Type: research

Efficacy of the GMALL ‐B‐ALL/NHL2002 Protocol in Burkitt Leukaemia/Lymphoma and Aggressive Non‐Hodgkin‐Lymphomas with or without CNS‐Involvement
ConclusionThis study confirmed the activity of the GMALL ‐B‐ALL/NHL2002 protocol in BL/B‐LBL. It was also effective in first‐line treated non‐BL/B‐LBL lymphomas with and without simultaneous CNS‐/peripheral involvement, but ineffective in relapsed/refractory disease.This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 24, 2018 Category: Hematology Authors: Maria Sakarou, Lewin Eisele, Ulrich D ührsen, Andreas Hüttmann Tags: Original Article Source Type: research

Increased survival due to lower toxicity for high ‐risk T‐cell acute lymphoblastic leukemia patients in two consecutive pediatric‐inspired PETHEMA trials
ConclusionPatients with T ‐cell ALL included in the HR‐11 trial showed better OS than patients in the HR‐03, mostly driven by a reduction of NRM. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 22, 2018 Category: Hematology Authors: Pere Barba, Mireia Morgades, Pau Montesinos, Cristina Gil, Mar ía‐Laura Fox, Juana Ciudad, María‐José Moreno, José González‐Campos, Eulàlia Genescà, Daniel Martínez‐Carballeira, Rodrigo Martino, Susana Vives, Ramon Guardia, Sa Tags: ORIGINAL ARTICLE Source Type: research

CTLA ‐4 polymorphism rs231775: influence on relapse and survival after allogeneic hematopoietic stem cell transplantation in childhood
ConclusionThis study suggests that CTLA ‐4 polymorphism rs231775 is relevant for relapse and survival after allogeneic HSCT in childhood and should be further investigated in clinical trials.This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 22, 2018 Category: Hematology Authors: Judith Hammrich, Susan Wittig, Thomas Ernst, Bernd Gruhn Tags: Original Article Source Type: research

Comparative risk of major bleeding with rivaroxaban and warfarin: Population ‐based cohort study of unprovoked venous thromboembolism
ConclusionsRivaroxaban was associated with a reduced risk of overall, gastrointestinal, and intracranial major bleeding vs warfarin in unprovoked VTE. No bleeding subtype was significantly more frequent in rivaroxaban patients. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 20, 2018 Category: Hematology Authors: Christine G. Kohn, Thomas J. Bunz, Jan Beyer ‐Westendorf, Craig I. Coleman Tags: ORIGINAL ARTICLE Source Type: research

Corrigendum
European Journal of Haematology, EarlyView. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 19, 2018 Category: Hematology Tags: CORRIGENDUM Source Type: research

Frequency and etiology of pulmonary hypertension in patients with myeloproliferative neoplasms
ConclusionIn the largest study ever reported, we found a lower prevalence of PH (3.8%) than previously reported. Screening for PH in unselected MPN patients is not justified.This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 19, 2018 Category: Hematology Authors: Mette Brabrand, Knud N ørregaard Hansen, Christian B. Laursen, Thomas Stauffer Larsen, Hanne Vestergaard, Niels Abildgaard Tags: Original Article Source Type: research

Bone marrow mononuclear cell telomere length in acute myeloid leukaemia and high ‐risk myelodysplastic syndrome
ConclusionIn patients with acute myeloid leukaemia or high ‐risk myelodysplastic syndrome, bone marrow mononuclear cell telomere length increased from diagnosis to remission. Furthermore, telomere length paradoxically was longer at higher age at diagnosis, even after adjusting for known risk factors of disease severity. Finally, we did not detect any prog nostic information in telomere length.This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 14, 2018 Category: Hematology Authors: Marie Warny, Jens Helby, Henrik Sengel øv, Børge G. Nordestgaard, Henrik Birgens, Stig E. Bojesen Tags: Original Article Source Type: research

Current practices in the management of adenovirus infection in allogeneic hematopoietic cell transplant recipients in Europe: The AdVance study
ConclusionsOur findings confirm that screening for AdV is more common in pediatric patients. Antiviral treatment is employed in both pediatric and adult patients, although adults are generally treated when AdV disease is diagnosed. The approach to AdV screening and treatment is risk ‐based and consistent with clinical guidelines.This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 12, 2018 Category: Hematology Authors: Marta Gonz ález‐Vicent, Marta Verna, Cécile Pochon, Aastha Chandak, Enrikas Vainorius, Tom Brundage, Essy Mozaffari, Garrett Nichols, Kanchan Rao Tags: Original Article Source Type: research

Issue Information
European Journal of Haematology, Volume 101, Issue 6, Page 709-710, December 2018. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 8, 2018 Category: Hematology Tags: ISSUE INFORMATION Source Type: research

Inhibitors in haemophilia A and B: Management of bleeds, inhibitor eradication, and strategies for difficult ‐to‐treat patients
This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 8, 2018 Category: Hematology Authors: Rolf Ljung, Guenter Auerswald, Gary Benson, Gerry Dolan, Anne Duffy, Cedric Hermans, Victor Jim énez‐Yuste, Thierry Lambert, Massimo Morfini, Silva Zupančić‐Šalek, Elena Santagostino Tags: Review Article Source Type: research

Back to the future: TFR and pregnancy in CML
This article is protected by copyright. All rights reserved. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 7, 2018 Category: Hematology Authors: Elisabetta Abruzzese, Paolo de Fabritiis, Malgorzata M Trawinska, Pasquale Niscola, Jane F Apperley, Michael J Mauro Tags: Letter to the Editor Source Type: research

CD79B mutations in primary vitreoretinal lymphoma: Diagnostic and prognostic potential
European Journal of Haematology,Volume 0, Issue ja, -Not available-. (Source: European Journal of Haematology)
Source: European Journal of Haematology - November 3, 2018 Category: Hematology Authors: Ichiro Yonese, Hiroshi Takase, Mayumi Yoshimori, Erika Onozawa, Akiho Tsuzura, Tohru Miki, Manabu Mochizuki, Osamu Miura, Ayako Arai Source Type: research

Molecular Pathogenesis of Acquired Aplastic Anemia
European Journal of Haematology,Volume 0, Issue ja, -Not available-. (Source: European Journal of Haematology)
Source: European Journal of Haematology - October 31, 2018 Category: Hematology Authors: Prajwal Chaitanya Boddu, Tapan Mahendra Kadia Source Type: research