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The prognostic role of echocardiographic indices in chronic heart failure: right ventricle revisitedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Farmakis, D., Parissis, J., Kremastinos, D. T. Tags: LETTER TO THE EDITOR Source Type: journals

Clinical trials update from the European Society of Cardiology Meeting 2009: AAA, RELY, PROTECT, ACTIVE-I, European CRT survey, German pre-SCD II registry, and MADIT-CRTEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article provides information and a commentary on trials relevant to the pathophysiology, prevention, and treatment of heart failure presented at the annual meeting of the European Society of Cardiology held in Barcelona in 2009. The AAA study does not support the routine use of aspirin for the prevention of vascular events in patients with asymptomatic atherosclerosis. RELY suggests that dabigatran may be more effective than warfarin for the prevention of stroke in patients with atrial fibrillation. Rolofylline was not superior to placebo in improving outcomes in patients with acute heart failure enrolled in the PROTE...
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Cleland, J. G.F., Coletta, A. P., Yassin, A., Buga, L., Torabi, A., Clark, A. L. Tags: MEETING REPORT Source Type: journals

'Hospital at home' care model as an effective alternative in the management of decompensated chronic heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Hospital at home care allows an important reduction in the costs during the index episode compared with hospital care, whilst maintaining similar outcomes with respect to cardiovascular mortality and morbidity and quality of life at 1 year follow-up. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Mendoza, H., Martin, M. J., Garcia, A., Aros, F., Aizpuru, F., Regalado De Los Cobos, J., Bello, M. C., Lopetegui, P., Cia, J. M. Tags: MANAGEMENT Source Type: journals

Depressive symptoms and outcomes in patients with heart failure: data from the COACH studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In patients with HF, depression is independently associated with poor outcomes. These findings highlight the need for continued exploration of whether improvements in depression lead to better cardiovascular outcomes. The study was registered at clinical trial (www.trialregister.nl): NCT 98675639. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Lesman-Leegte, I., van Veldhuisen, D. J., Hillege, H. L., Moser, D., Sanderman, R., Jaarsma, T. Tags: DEPRESSION Source Type: journals

Effect of simvastatin vs. rosuvastatin on adiponectin and haemoglobin A1c levels in patients with non-ischaemic chronic heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These findings suggest that hydrophilic rosuvastatin but not lipophilic simvastatin increases adiponectin and decreases HbA1c levels in patients with NICHF. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Tsutamoto, T., Yamaji, M., Kawahara, C., Nishiyama, K., Fujii, M., Yamamoto, T., Horie, M. Tags: TREATMENT Source Type: journals

The obesity paradox in stable chronic heart failure does not persist after matching for indicators of disease severity and confoundersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The obesity paradox does not appear to persist in a matched setting with respect to indicators of disease severity and other confounders. NT-proBNP remains an independent prognostic indicator of adverse outcome irrespective of obesity status. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Frankenstein, L., Zugck, C., Nelles, M., Schellberg, D., Katus, H. A., Remppis, B. A. Tags: PROGNOSIS Source Type: journals

The impact of concurrent heart failure on prognosis in patients with chronic obstructive pulmonary diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Heart failure is a strong independent predictor of all-cause mortality in patients with a diagnosis of COPD. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Boudestein, L. C.M., Rutten, F. H., Cramer, M. J., Lammers, J. W. J., Hoes, A. W. Tags: PROGNOSIS Source Type: journals

Cardiac mortality in {beta}-thalassemia major: resting but not dobutamine stress echocardiography predicts mortality among initially cardiac disease-free patients in a prospective 12-year studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Hahalis, G., Kourakli, A., Gerasimidou, I., Kalogeropoulos, A. P., Sitafidis, G., Papageorgiou, U., Davlouros, P., Grapsas, N., Zoumbos, N. C., Alexopoulos, D. Tags: ECHOCARDIOGRAPHY Source Type: journals

Right atrial size and deformation in patients with dilated cardiomyopathy undergoing cardiac resynchronization therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Right atrial area index was increased and RA myocardial deformation was impaired in patients with DCM who were non-responders to CRT. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: D'Andrea, A., Scarafile, R., Riegler, L., Salerno, G., Gravino, R., Cocchia, R., Castaldo, F., Allocca, F., Limongelli, G., Di Salvo, G., Cuomo, S., Pacileo, G., Caso, P., Russo, M. G., Calabro, R. Tags: ECHOCARDIOGRAPHY Source Type: journals

Increased plasma retinol binding protein 4 levels in patients with inflammatory cardiomyopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Elevated RBP 4 plasma concentrations, induced by IL-8, might be one mechanism leading to a higher incidence of diabetes in patients with DCMi. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Bobbert, P., Weithauser, A., Andres, J., Bobbert, T., Kuhl, U., Schultheiss, H. P., Rauch, U., Skurk, C. Tags: BIOMARKERS Source Type: journals

Red cell distribution width: an inexpensive and powerful prognostic marker in heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Red cell distribution width is a readily available test in the HF-population with similar independent prognostic power to NT-proBNP across the first to third quartiles. Prognostic models in HF should include RDW and further investigation is necessary to determine the pathological mechanism of the relationship. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Al-Najjar, Y., Goode, K. M., Zhang, J., Cleland, J. G.F., Clark, A. L. Tags: BIOMARKERS Source Type: journals

Red cell distribution width has incremental prognostic value to B-type natriuretic peptide in acute heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Jackson, C. E., Dalzell, J. R., Bezlyak, V., Tsorlalis, I. K., Myles, R. C., Spooner, R., Ford, I., Petrie, M. C., Cobbe, S. M., McMurray, J. J.V. Tags: BIOMARKERS Source Type: journals

Implementation of device therapy (cardiac resynchronization therapy and implantable cardioverter defibrillator) for patients with heart failure in Europe: changes from 2004 to 2008Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Implantation rates of devices for HF, in particular ICD and CRT-D, have increased significantly between 2004 and 2008 in Europe, but there remain major differences between countries. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: van Veldhuisen, D. J., Maass, A. H., Priori, S. G., Stolt, P., van Gelder, I. C., Dickstein, K., Swedberg, K. Tags: EPIDEMIOLOGY Source Type: journals

Heart failure in patients hospitalized with acute coronary syndromes: observations from the Gulf Registry of Acute Coronary Events (Gulf RACE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Heart failure complicates a substantial proportion of ACS admissions in the Arab Middle East and is associated with higher in-hospital death. Younger patients with ACS have a higher relative increase in mortality related to HF. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Alsheikh-Ali, A. A., Al-Mallah, M. H., Al-Mahmeed, W., Albustani, N., Al Suwaidi, J., Sulaiman, K., Zubaid, M., for the Gulf RACE Investigators Tags: EPIDEMIOLOGY Source Type: journals

Normal systolic blood pressure and risk of heart failure in US male physiciansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Our findings suggest a linear relationship between normotensive SBP and HF risk. Strategies to prevent HF, such as lifestyle modification, should be emphasized across all blood pressure ranges. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Britton, K. A., Gaziano, J. M., Djousse, L. Tags: EPIDEMIOLOGY Source Type: journals

Impaired cellular contractile function in thiamine-deficient rat cardiomyocytesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Gioda, C. R., Roman-Campos, D., Carneiro-Junior, M. A., da Silva, K. A., de Souza, M. O., Mendes, L. J., Natali, A. J., Cruz, J. S. Tags: EXPERIMENTAL Source Type: journals

Food-restriction in obese dyslipidaemic diabetic mice partially restores basal contractility but not contractile reserveEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Food-restriction in obese diabetic mice leads to improved cardiac performance by diminishing cardiac load and by ameliorating the intrinsic contractile properties of the cardiac muscle. However, cardiac reserve under dobutamine stimulation did not increase. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Van den Bergh, A., Vangheluwe, P., Vanderper, A., Carmeliet, P., Wuytack, F., Janssens, S., Flameng, W., Holvoet, P., Herijgers, P. Tags: EXPERIMENTAL Source Type: journals

Acute coronary syndromes, heart failure, and diabetes in the Gulf Registry of Acute Coronary EventsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Rosengren, A. Tags: EDITORIALS Source Type: journals

The Nobel Prize for medicine for telomere biology and relevance to heart failure researchEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: van der Harst, P., de Boer, R. A., van Veldhuisen, D. J. Tags: EDITORIALS Source Type: journals

What is the relationship between cardiac and peripheral ghrelin production? ReplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Lund, L. H., Freda, P., Mancini, D. M. Tags: LETTERS TO THE EDITOR Source Type: journals

Ghrelin resistance in heart failure or why failing cardiomyocytes do not produce ghrelin: the same problem?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Beiras-Fernandez, A., Weis, F., Reichart, B. Tags: LETTERS TO THE EDITOR Source Type: journals

Chronic Heart Failure (Oxford Cardiology Library)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: McIntyre, H. F. Tags: BOOK REVIEW Source Type: journals

Severe cardiomyopathy following treatment with the tumour necrosis factor-{alpha} inhibitor adalimumab for Crohn's diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Adalimumab belongs to the group of tumour necrosis factor- inhibitors and has been approved for the treatment Crohn's Disease since 2007. Herein we report a severe adverse reaction to adalimumab in a 25-year-old female patient. One week after the initial-dose of adalimumab (160 mg), which was initiated due to an acute exacerbation of Crohn's disease, the patient developed a fulminant cardiomyopathy. In severe cardiogenic shock, the patient required an extracorporeal membrane-oxygenation system for 8 days until cardiac recovery. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Emmert, M. Y., Salzberg, S. P., Emmert, L. S., Behjati, S., Plass, A., Felix, C., Falk, V., Gruenenfelder, J. Tags: CASE REPORT Source Type: journals

Timing of eplerenone initiation and outcomes in patients with heart failure after acute myocardial infarction complicated by left ventricular systolic dysfunction: insights from the EPHESUS trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion An earlier eplerenone administration (3–7days) post-AMI improved outcomes in patients with LVSD and HF. This benefit was not observed when eplerenone was initiated later (≥7days). (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Adamopoulos, C., Ahmed, A., Fay, R., Angioi, M., Filippatos, G., Vincent, J., Pitt, B., Zannad, F., the EPHESUS Investigators Tags: CLINICAL TRIALS Source Type: journals

Adherence to medication according to sex and age in the CHARM programmeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Women, particularly those <75 years of age, were less likely to be adherent in this large sample of patients with symptomatic heart failure. Understanding factors associated with adherence may provide opportunities for intervention. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Granger, B. B., Ekman, I., Granger, C. B., Ostergren, J., Olofsson, B., Michelson, E., McMurray, J. J.V., Yusuf, S., Pfeffer, M. A., Swedberg, K. Tags: CLINICAL TRIALS Source Type: journals

Rationale and design of Ferinject(R) Assessment in patients with IRon deficiency and chronic Heart Failure (FAIR-HF) study: a randomized, placebo-controlled study of intravenous iron supplementation in patients with and without anaemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion This study will provide evidence on the efficacy and safety of iron repletion with ferric carboxymaltose in CHF patients with ID with and without anaemia. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Anker, S. D., Colet, J. C., Filippatos, G., Willenheimer, R., Dickstein, K., Drexler, H., Luscher, T. F., Mori, C., von Eisenhart Rothe, B., Pocock, S., Poole-Wilson, P. A., Ponikowski, P., on behalf of the FAIR-HF committees and investigators Tags: CLINICAL TRIALS Source Type: journals

Is taking part in clinical trials good for your health? A cohort studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Those patients with chronic heart failure who express a willingness to take part in a clinical trial, appear to have a better prognosis than those who do not. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Clark, A. L., Lammiman, M. J., Goode, K., Cleland, J. G.F. Tags: CLINICAL TRIALS Source Type: journals

The safety and tolerability of darbepoetin alfa in patients with anaemia and symptomatic heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Darbepoetin alfa was well tolerated with an AE profile similar to placebo in HF subjects treated to a target Hb of 14.0 ± 1.0 g/dL. Contrary to recent data in other patient populations, there was no evidence of increased risk of mortality or cardiovascular events. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Klapholz, M., Abraham, W. T., Ghali, J. K., Ponikowski, P., Anker, S. D., Knusel, B., Sun, Y., Wasserman, S. M., van Veldhuisen, D. J. Tags: ANAEMIA Source Type: journals

Sleep apnoea induces cardiac electrical instability assessed by T-wave alternans in patients with congestive heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In CHF patients, sleep apnoea induces cardiac electrical instability manifested as TWA, reflecting increased risk of nocturnal SCD. Moreover, some CHF patients with sleep apnoea exhibit nighttime predominant TWA. Therefore, TWA should also be evaluated during the night. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Takasugi, N., Nishigaki, K., Kubota, T., Tsuchiya, K., Natsuyama, K., Takasugi, M., Nawa, T., Ojio, S., Aoyama, T., Kawasaki, M., Takemura, G., Minatoguchi, S. Tags: SLEEP APNOEA Source Type: journals

Serum levels of large tenascin-C variants, matrix metalloproteinase-9, and tissue inhibitors of matrix metalloproteinases in concentric versus eccentric left ventricular hypertrophyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Our data suggest that myocardial remodelling in LVH is associated with changes in serum levels of MMP-9, TIMP-1, -2, -4, and Tn-C splice variants. In addition, B domain containing Tn-C discriminated EH from CH and might be suggested as a potential diagnostic marker. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Franz, M., Berndt, A., Altendorf-Hofmann, A., Fiedler, N., Richter, P., Schumm, J., Fritzenwanger, M., Figulla, H. R., Brehm, B. R. Tags: BIOMARKERS Source Type: journals

Decreased soluble TWEAK levels predict an adverse prognosis in patients with chronic stable heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In contrast to other cytokines shown to be increased in heart failure patients, plasma levels of sTWEAK are significantly reduced in chronic stable heart failure. In addition, lower plasma levels of sTWEAK predict an adverse prognosis independent of established risk markers such as NT-proBNP. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Chorianopoulos, E., Rosenberg, M., Zugck, C., Wolf, J., Katus, H. A., Frey, N. Tags: BIOMARKERS Source Type: journals

Adjusting for clinical covariates improves the ability of B-type natriuretic peptide to distinguish cardiac from non-cardiac dyspnoea: a sub-study of HEARD-ITEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Adjusting BNP for important covariates may improve its ability to distinguish cardiac from non-cardiac dyspnoea. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Rogers, R. K., Stehlik, J., Stoddard, G. J., Greene, T., Collins, S. P., Peacock, W. F., Maisel, A. D., Clopton, P., Michaels, A. D. Tags: BIOMARKERS Source Type: journals

Lipoprotein components and risk of congestive heart failure in 84 740 men and women in the Apolipoprotein MOrtality RISk study (AMORIS)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Over and above adjustment factors, the apoB/apoA-1 ratio and TG were the most predictive of the LC, but all LC were highly significantly related to the development of HF. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Holme, I., Aastveit, A. H., Hammar, N., Jungner, I., Walldius, G. Tags: EPIDEMIOLOGY Source Type: journals

The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Moller, D. V., Pham, T. T., Gustafsson, F., Hedley, P., Ersboll, M. K., Bundgaard, H., Andersen, C. B., Torp-Pedersen, C., Kober, L., Christiansen, M. Tags: GENETICS Source Type: journals

Transplantation with survivin-engineered mesenchymal stem cells results in better prognosis in a rat model of myocardial infarctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Transplantation with SVV-engineered MSCs by lentiviral vector leads to better prognosis for MI by enhancing cellular survival. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Fan, L., Lin, C., Zhuo, S., Chen, L., Liu, N., Luo, Y., Fang, J., Huang, Z., Lin, Y., Chen, J. Tags: EXPERIMENTAL Source Type: journals

Clinical trial participation: are we studying the patients we are trying to treat?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - October 29, 2009 Category: Cardiology Authors: Wang, O. J., Krumholz, H. M. Tags: EDITORIAL Source Type: journals

Staged heart transplantation and chemotherapy as a treatment option in patients with severe cardiac light-chain amyloidosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Heart transplantation in advanced cardiac amyloidosis is a promising approach to interrupting the vicious circle of ineligibility for potential curative chemotherapeutic treatment and extremely poor prognosis of cardiac amyloidosis without chemotherapy. Highly urgent heart transplantation combined with subsequent HDM–ASCT appears to offer a successful treatment option to improve the poor outcome of cardiac amyloidosis. However, it should be restricted to highly selected patients in specialized centres. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Kristen, A. V., Sack, F.-U., Schonland, S. O., Hegenbart, U., Helmke, B. M., Koch, A., Schnabel, P. A., Rocken, C., Hardt, S., Remppis, A., Goldschmidt, H., Karck, M., Ho, A. D., Katus, H. A., Dengler, T. J. Tags: HEART TRANSPLANTATION Source Type: journals

Elevated serum uric acid levels following heart transplantation predict all-cause and cardiac mortalityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Elevated SUA at 1 year post-HTx, or a modest rather than a marked decline in SUA levels during the first year post-HTx, is associated with an increased risk of mortality. Although the pathophysiological mechanism is unclear, our data indicate a potential relationship between SUA and inflammation which should be explored further. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Arora, S., Aukrust, P., Ueland, T., Broch, K., Simonsen, S., Gude, E., Fiane, A. E., Geiran, O., Wergeland, R., Andreassen, A. K., Gullestad, L. Tags: HEART TRANSPLANTATION Source Type: journals

Significance of anaemia in patients with advanced heart failure receiving long-term mechanical circulatory supportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Anaemia is related to adverse outcomes in patients receiving prolonged LVAD support. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Vrtovec, B., Radovancevic, R., Delgado, R. M., Radovancevic, B., Bracey, A. W., Gregoric, I. D., Frazier, O.H. Tags: DEVICES Source Type: journals

Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Hawthorn provides no symptomatic or functional benefit when given with standard medical therapy to patients with heart failure. This trial is registered in ClinicalTrials.gov ID: NCT00343902. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Zick, S. M., Vautaw, B. M., Gillespie, B., Aaronson, K. D. Tags: CLINICAL TRIAL Source Type: journals

A randomized, double-blind, placebo-controlled study to determine the effects of valsartan on exercise time in patients with symptomatic heart failure with preserved ejection fractionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In this population, which predominantly included patients with well-controlled hypertension and symptomatic HFPEF, addition of valsartan did not increase exercise time within 14 weeks. However, valsartan 320 mg reduced blood pressure and improved symptoms of perceived exertion (Borg score) during exercise and was generally well-tolerated. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Parthasarathy, H. K., Pieske, B., Weisskopf, M., Andrews, C. D., Brunel, P., Struthers, A. D., MacDonald, T. M. Tags: TREATMENT Source Type: journals

Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial infarction (REPAIR-AMI) trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Intracoronary administration of BMC eliminates the correlation between depressed LVEF after reperfusion therapy and LV expansion during follow-up and, thereby, abrogates early LV remodelling after AMI. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Schachinger, V., Assmus, B., Erbs, S., Elsasser, A., Haberbosch, W., Hambrecht, R., Yu, J., Corti, R., Mathey, D. G., Hamm, C. W., Tonn, T., Dimmeler, S., Zeiher, A. M., for the REPAIR-AMI investigators Tags: TREATMENT Source Type: journals

Plasma B-type natriuretic peptide and anti-inflammatory cytokine interleukin-10 levels predict adverse clinical outcome in chronic heart failure patients with depressive symptoms: a 1-year follow-up studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Neurohormonal activation and defective anti-inflammatory properties are independent predictors of long-term outcome in hospitalized CHF patients with depressive symptoms. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Parissis, J. T., Farmakis, D., Nikolaou, M., Birmpa, D., Bistola, V., Paraskevaidis, I., Ikonomidis, I., Gaitani, S., Venetsanou, K., Filippatos, G., Kremastinos, D. Th. Tags: BIOMARKERS Source Type: journals

Brain natriuretic peptide for the prediction of sudden cardiac death and ventricular arrhythmias: a meta-analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The measurement of BNP has significant value in predicting SCD and VA. However, the benefit of BNP testing in addition to other risk stratification tests is unclear and BNP needs to be evaluated prospectively in combination with other complementary risk stratification tools. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Scott, P. A., Barry, J., Roberts, P. R., Morgan, J. M. Tags: BIOMARKERS Source Type: journals

Regional abnormalities of myocardial deformation in patients with hypertrophic cardiomyopathy: correlations with delayed enhancement in cardiac magnetic resonanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Areas of reduced left ventricular contractility in deformation analysis are associated with delayed CMR enhancement in patients with HCM. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Ghio, S., Revera, M., Mori, F., Klersy, C., Raisaro, A., Raineri, C., Serio, A., Pasotti, M., Visconti, L. O. Tags: IMAGING Source Type: journals

Left ventricular remodelling and torsional dynamics in dilated cardiomyopathy: reversed apical rotation as a marker of disease severityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Reversed apical rotation and loss of LV torsion in patients with DCM is associated with significant LV remodelling, increased electrical dyssynchrony, reduced systolic function, and increased filling pressures, indicating a more advanced disease stage. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Popescu, B. A., Beladan, C. C., Calin, A., Muraru, D., Deleanu, D., Rosca, M., Ginghina, C. Tags: IMAGING Source Type: journals

Gender differences in survival in patients with severe left ventricular dysfunction despite similar extent of myocardial scar measured on cardiac magnetic resonanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In patients with CAD and severely reduced LVEF, women have worse outcomes than men, irrespective of myocardial scar burden. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Kwon, D. H., Halley, C. M., Popovic, Z. B., Carrigan, T. P., Zysek, V., Setser, R., Schoenhagen, P., Flamm, S. D., Starling, R. C., Desai, M. Y. Tags: PROGNOSIS Source Type: journals

Independent relationship of left atrial size and mortality in patients with heart failure: an individual patient meta-analysis of longitudinal data (MeRGE Heart Failure)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Left atrial area is a powerful predictor of outcome among HF patients with predominantly impaired systolic function, and is independent of, and provides additional prognostic information beyond LV systolic and diastolic function. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Rossi, A., Temporelli, P. L., Quintana, M., Dini, F. L., Ghio, S., Hillis, G. S., Klein, A. L., Ajmone Marsan, N., Prior, D. L., Yu, C. M., Poppe, K. K., Doughty, R. N., Whalley, G. A., on behalf of the MeRGE Heart Failure Collaborators Tags: PROGNOSIS Source Type: journals

Intake of very long chain n-3 fatty acids from fish and the incidence of heart failure: the Rotterdam StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Our findings do not support a major role for fish intake in the prevention of heart failure. The potentially protective effect of EPA plus DHA in diabetic patients, however, warrants further investigation. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Dijkstra, S. C., Brouwer, I. A., van Rooij, F. J.A., Hofman, A., Witteman, J. C.M., Geleijnse, J. M. Tags: EPIDEMIOLOGY Source Type: journals

The accelerated post-infarction progression of cardiac remodelling is associated with genetic changes in an untreated streptozotocin-induced diabetic rat modelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The present data suggest that hyperglycaemia up-regulates remodelling-related genes, which may be responsible for the worse outcomes in diabetics than in non-diabetics after AMI. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - September 28, 2009 Category: Cardiology Authors: Song, G.-Y., Wu, Y.-J., Yang, Y.-J., Li, J.-J., Zhang, H.-L., Pei, H.-J., Zhao, Z.-Y., Zeng, Z.-H., Hui, R.-T. Tags: EXPERIMENTAL Source Type: journals