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621 records returned

Professionalism beyond medical school: an educational continuum?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article describes the attention currently paid to professionalism in the residency programmes, differences in perception of professionalism between patients, faculty, students and residents, differences in professionalism issues in the different educational phases, as well as their consequences for training and assessment regarding professionalism. Continuous medical education in professionalism is thereafter briefly discussed. PMID: 19892294 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: van Mook WN, Gorter SL, de Grave WS, van Luijk SJ, O'Sullivan H, Wass V, Zwaveling JH, Schuwirth LW, van der Vleuten CP Tags: Eur J Intern Med Source Type: journals

Approaches to professional behaviour assessment: tools in the professionalism toolbox.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is general agreement that professionalism and professional behaviour should be (formatively and summatively) assessed, but consensus on how this should be done is still lacking. After discussing some of the remaining issues and questions regarding professionalism assessment, this article discusses the importance of qualitative comments to the assessment of professional behaviour, focuses on the currently most frequently used tools, as well as stresses the need for triangulation (combining) of these tools. PMID: 19892295 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: van Mook WN, Gorter SL, O'Sullivan H, Wass V, Schuwirth LW, van der Vleuten CP Tags: Eur J Intern Med Source Type: journals

Cryoglobulins not HCV-related and solid tumors: retrospective analysis from a series of 493 patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19892296 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Rullier P, Le Quellec A, Cognot C Tags: Eur J Intern Med Source Type: journals

Statin induced angiogenesis and tumour growth.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19892297 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Mascitelli L, Pezzetta F, Goldstein MR Tags: Eur J Intern Med Source Type: journals

Emotional stress and sudden death: the role of cathecholaminergic polymorphic ventricular tachycardia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19892298 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Iyer HV Tags: Eur J Intern Med Source Type: journals

New antiplatelet agents: why they are needed.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite recent advances in the treatment of acute coronary syndromes (ACS), including dual antiplatelet therapy with aspirin and a thienopyridine during the acute phase and for secondary prevention, this condition remains a leading cause of morbidity and mortality. The limitations of the currently available antiplatelet agents have triggered the development of newer drugs. In this review we summarize the mechanisms of actions and results of current clinical trials of novel antiplatelet agents. These include prasugrel, a thienopyridine prodrug which has a mechanism similar to that of clopidogrel but superior pharmacokin...
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Franchini M, Mannucci PM Tags: Eur J Intern Med Source Type: journals

Lessons from acute pancreatitis-induced thrombotic thrombocytopenic purpura.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Acute pancreatitis is an inflammatory disease characterized by local tissue injury which can trigger a systemic inflammatory response. There is increasing evidence that endothelial dysfunction is one of the critical pathophysiologic manifestations in patients with severe form of acute pancreatitis. In keeping with this, there have been recent reports of a haematological disorder, thrombotic thrombocytopenic purpura (TTP), as being precipitated by acute pancreatitis. However, the patients who develop TTP, secondary to acute pancreatitis, do not always have the characteristic low levels of VonWillebrand multimer cleaving...
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Thachil J Tags: Eur J Intern Med Source Type: journals

Prevention of strongyloides hyperinfection syndrome: a rheumatological point of view.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Since there is no evidence on the prophylaxis of SHS in immunosuppressed rheumatic patients, the suggested regimen for that prophylaxis may rely on the results obtained from therapeutical studies. Ivermectin has the best safety profile, lower cost and best efficacy and should be the drug of choice for the prophylaxis of SHS in such patients. Although a definitive prophylactic regimen has not been defined, the option for 200 microg/kg/day for 2 days, repeated within 2 weeks, seems to be a reasonable approach. Such regimen should be repeated every 6 months in case of persisting immunosuppression in permanent res...
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Santiago M, Leitão B Tags: Eur J Intern Med Source Type: journals

Peptidylarginine deiminases and the pathogenesis of rheumatoid arthritis: a reflection of the involvement of transglutaminase in coeliac disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Post-translational modifications are associated with certain autoimmune diseases. For example, in the initial steps of coeliac disease (CD), transglutaminase type 2 (TG2) catalyzes a post-translational deamidation of specific glutamine residues in dietary gluten, resulting in antibodies against both modified gliadin and against TG2. Anti-TG2 has become a specific biomarker for CD. In rheumatoid arthritis (RA), the presence of antibodies against citrullinated peptides (ACPA) characterizes a distinct subset of this inflammatory disorder. Moreover, antibodies against the enzyme that catalyzes the citrullination (peptidyla...
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Stenberg P, Roth B, Wollheim FA Tags: Eur J Intern Med Source Type: journals

Thromboembolic and haemorrhagic events in permanent atrial fibrillation: observational study in an emergency department.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: OT is well-tolerated even in elderly patients, with a low rate of haemorrhagic events. In clinical practice OT is underused, in particular in older patients, in spite of a high number of thrombotic events. PMID: 19892303 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Rovellini A, Folli C, Cardani F, Monzani V Tags: Eur J Intern Med Source Type: journals

Ambulatory blood pressure monitoring in stroke survivors: do we really control our patients?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Survivors of stroke, both hypertensive and non-hypertensive patients, present a chronic disruption of circadian rhythm of BP. Conventional clinical recordings are an unreliable method of controlling these patients and ABPM should be routinely performed in this population. PMID: 19892304 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Castilla-Guerra L, Fernández-Moreno Mdel C, Espino-Montoro A, López-Chozas JM Tags: Eur J Intern Med Source Type: journals

Clinical outcomes in medical outliers admitted to hospital with heart failure.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Patients admitted to the Department of Internal Medicine with heart failure had a longer stay if they initially start in other departments' wards. Significant differences were not seen in this group of patients with respect to mortality, readmission, or intra-hospital morbidity. PMID: 19892305 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Alameda C, Suárez C Tags: Eur J Intern Med Source Type: journals

Therapeutic implications of low lymphocyte count in non-ST segment elevation acute coronary syndromes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: LLC identifies a subgroup of patients with greater reduction in the risk of postdischarge MI when a RIS is applied. PMID: 19892306 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Núñez J, Sanchis J, Bodí V, Núñez E, Heatta AM, Miñana G, Merlos P, Rumiz E, Palau P, Sanjuán R, Blasco ML, Llàcer A Tags: Eur J Intern Med Source Type: journals

Evaluation of in vivo antineoplastic effects of rapamycin in patients with chemotherapy-refractory AML.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Rapamycin at 2mg per day acts mildly cytoreductive in a subgroup of patients with refractory AML. Higher doses and drug combinations may be required to obtain long lasting anti-leukemic effects in these patients. PMID: 19892307 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Boehm A, Mayerhofer M, Herndlhofer S, Knoebl P, Sillaber C, Sperr WR, Jaeger U, Valent P Tags: Eur J Intern Med Source Type: journals

Application of HRV-CD for estimation of life expectancy in various clinical disorders.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Diminished HRV-CD is associated with heart failure, coronary artery disease, cardiac arrhythmia, renal dysfunction, diabetes mellitus and low serum potassium. Among the latter, heart failure is most significantly associated with decreased HRV-CD. Decreased HRV-CD values, especially in diabetics, are also associated with lower survival. PMID: 19892308 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Almoznino-Sarafian D, Sarafian G, Zyssman I, Shteinshnaider M, Tzur I, Kaplan BZ, Berman S, Cohen N, Gorelik O Tags: Eur J Intern Med Source Type: journals

Diagnostic performance in a primary referral hospital assessed by autopsy: evolution over a ten-year period.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Autopsy remains a valuable tool to measure diagnostic performance. Errors occur most frequently in cardiovascular events, whereas in malignant and neurological diseases they are rare. The significant improvement of diagnostic accuracy for cardiovascular diseases is associated with the introduction of new sensitive laboratory tests and algorithms for thoracic pain and thromboembolic diseases. PMID: 19892309 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Thurnheer R, Hoess C, Doenecke C, Moll C, Muntwyler J, Krause M Tags: Eur J Intern Med Source Type: journals

Do PubMed and Google searches help medical students and young doctors reach the correct diagnosis? A pilot study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: We believe that these preliminary findings justify the induction of further studies in order to clarify whether resources such as PubMed and Google may substantially aid physicians and medical students in the differential diagnosis process. PMID: 19892310 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - November 8, 2009 Category: Internal Medicine Authors: Falagas ME, Ntziora F, Makris GC, Malietzis GA, Rafailidis PI Tags: Eur J Intern Med Source Type: journals

Clinical manifestations and laboratory tests in biopsy proven giant cell arteritis in Glasgow.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19818282 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Aziz S, Al-Ansari A, Bankart J, McFadzean R Tags: Eur J Intern Med Source Type: journals

High levels of tumor markers in pleural fluid correlate with poor survival in patients with adenocarcinomatous or squamous malignant effusions.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19818283 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Singh SK, Bhargava R, Gupta V Tags: Eur J Intern Med Source Type: journals

The role of angiogenesis in solid tumours: An overview.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Angiogenesis is the physiological process of the formation of new blood vessels from pre-existing ones. Multiple molecules regulate angiogenesis, such as the vascular endothelial growth factor, angiopoietins, the fibroblast growth factor, the platelet-derived growth factor and the transforming growth factor-beta. Angiogenesis plays an important role in the growth, progression and metastasis of a tumour. Inhibiting the angiogenic process or targeting existing tumour vessels can be used for treatment of tumours as an alternative or in parallel with conventional chemotherapy. Many anti-angiogenic factors are under investi...
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Makrilia N, Lappa T, Xyla V, Nikolaidis I, Syrigos K Tags: Eur J Intern Med Source Type: journals

Atrial fibrillation: Mechanistic insights and treatment options.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Atrial fibrillation (AF) remains the most common clinically encountered arrhythmia. Unlike supraventricular arrhythmias that use a defined mechanism, AF involves a wide spectrum of arrhythmias from lone AF to paroxysmal to chronic AF. AF is an arrhythmia that may develop in several ways. Mechanical remodeling manifests as decreased atrial contractility and increased atrial compliance which leads to a stretch of the atrial myocardium. Atrial remodeling may also increase in atrial fibrosis which can slow conduction velocity and can shorten the refractory period in atria with long-standing AF. It is still unclear whether ...
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Mathew ST, Patel J, Joseph S Tags: Eur J Intern Med Source Type: journals

ACTH-producing pheochromocytoma: Clinical considerations and concise review of the literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a patient with a rare cause of ectopic ACTH-dependent Cushing's syndrome, caused by a pheochromocytoma. The case provides clues for a detailed discussion on the pitfalls and diagnostic difficulties in establishing the correct underlying cause of ACTH-dependent Cushing's syndrome. It clearly demonstrates that the relative contributions of clinical, biochemical, and radiological clues in establishing the correct underlying cause of Cushing's syndrome may differ considerably between Cushing's disease and Cushing's syndrome due to ectopic overproduction of ACTH. In addition, the literature concerning ACTH-producing ...
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Nijhoff MF, Dekkers OM, Vleming LJ, Smit JW, Romijn JA, Pereira AM Tags: Eur J Intern Med Source Type: journals

Minimally invasive management of biliary complications after laparoscopic cholecystectomy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Most patients with bile leakage can be managed successfully by percutaneous drainage. If biliary output does not decrease, endoscopy is needed. In patients with jaundice endoscopic diagnostic and therapeutic procedures should be performed immediately. PMID: 19818287 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Zerem E, Omerović S Tags: Eur J Intern Med Source Type: journals

Risk factors for delirium tremens in patients with alcohol withdrawal syndrome in a hospital setting.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Three clinical findings (seizures, blood pressure and temperature) can aid in identifying patients with AWS who are likely to develop DTs. The model's predictive capacity is not high. PMID: 19818288 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Monte R, Rabuñal R, Casariego E, Bal M, Pértega S Tags: Eur J Intern Med Source Type: journals

The prevalence of Helicobacter pylori in obese subjects.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: In our study, we determined that prevalence of H. pylori increased in subjects with obesity. We consider that obesity can be a risk factor for H. pylori infection. However, further studies evaluating more subjects are required. PMID: 19818289 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Arslan E, Atılgan H, Yavaşoğlu I Tags: Eur J Intern Med Source Type: journals

Hepatitis B remains a major health priority in Western Balkans: Results of a 4-year prospective Greek-Albanian collaborative study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The HEPAGA I study showed a decrease in the prevalence of chronic HBV infection in Albania compared to that of the previous decade. The HEPAGA II study demonstrated that health care consumption due to HBV infection is still an important determinant of the overall health consumption in Western Balkans. PMID: 19818290 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Katsanos KH, Christodoulou DK, Zervou E, Babameto A, Craja B, Hyphantis H, Karetsos V, Tsonis G, Basho J, Resuli BF, Tsianos EV Tags: Eur J Intern Med Source Type: journals

Oxidative stress and thyroid hormones in patients with liver diseases.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The measurement of the total T(3), NO, MDA, GSH reduced and GSHPx as biomarkers for liver diseases might be a beneficial tool, helping in monitoring the state of liver disease patients. PMID: 19818291 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Moustafa AH, Ali EM, Mohamed TM, Abdou HI Tags: Eur J Intern Med Source Type: journals

Determinants of a positive response to carotid sinus massage and head-up tilt testing.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Male sex, increasing age and being referred with syncope were all associated with an increased likelihood of receiving a diagnosis of either OH or CSH. The overall prevalence of CSH was lower than in previous studies, which may reflect different patient populations. PMID: 19818292 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Milton JC, Lee TC, Jackson SH Tags: Eur J Intern Med Source Type: journals

Relation of inflammatory chemokines to insulin resistance and hypoadiponectinemia in coronary artery disease patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Obese CAD patients with MS have a more pronounced increase of MCP-1, IL-8 and HOMA-IR and more decreased adiponectin levels than non-obese CAD patients without MS. PMID: 19818293 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Tretjakovs P, Jurka A, Bormane I, Mackevics V, Mikelsone I, Balode L, Reihmane D, Stukena I, Bahs G, Aivars JI, Pirags V Tags: Eur J Intern Med Source Type: journals

Upper limb musculoskeletal abnormalities and poor metabolic control in diabetes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Upper limb locomotor abnormalities are very common in diabetes and are associated with worse glycaemic control and more diabetic complications. Assessment of upper limb locomotor disease in diabetes should include an estimate of glycaemic control and a search for other complications. PMID: 19818294 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Ramchurn N, Mashamba C, Leitch E, Arutchelvam V, Narayanan K, Weaver J, Hamilton J, Heycock C, Saravanan V, Kelly C Tags: Eur J Intern Med Source Type: journals

eGFR and creatinine clearance in relation to metabolic changes in an unselected patient population.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Metabolic changes in an in- and outpatient hospital population are present at earlier stages than was stated in recent guidelines, especially when creatinine clearance levels are used as indicators. This might have implications for testing and treatment of patients with suspected kidney disease and/or loss of renal function. PMID: 19818295 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Drion I, Joosten H, Dikkeschei LD, Groenier KH, Bilo HJ Tags: Eur J Intern Med Source Type: journals

Iatrogenic intravenous medication errors reported to the GIZ-Nord Poisons Center Göttingen.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: IIME increased from 1997 to 2006. Intravenous use of antipsychotics and theophylline should be restricted to a minimum. PMID: 19818296 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 13, 2009 Category: Internal Medicine Authors: Deters M, Prasa D, Hentschel H, Schaper A Tags: Eur J Intern Med Source Type: journals

Invasive aspergillosis in non-neutropenic patients.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782903 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Kaiser P, Thurnheer R, Moll C, Frauchiger B, Rochat P, Krause M Tags: Eur J Intern Med Source Type: journals

Fatal lactic acidosis after prolonged linezolid exposure for treatment of multidrug-resistant tuberculosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782904 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Boutoille D, Grossi O, Depatureaux A, Tattevin P Tags: Eur J Intern Med Source Type: journals

A case of thyroid storm following radioiodine therapy underlying usefulness of cardiac MRI.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782905 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Thebault C, Leurent G, Potier J, Bedossa M, Bonnet F Tags: Eur J Intern Med Source Type: journals

Diagnostic and therapeutic opportunities in hypertension and prehypertension.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782906 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Jolobe OM Tags: Eur J Intern Med Source Type: journals

Omalizumab administration in Churg-Strauss syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782907 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Giavina-Bianchi P, Kalil J Tags: Eur J Intern Med Source Type: journals

RS3PE Syndrome: extending spectrum?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782908 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Alvarez Díaz H Tags: Eur J Intern Med Source Type: journals

Spontaneous bacterial peritonitis presenting with a very high leukocyte count in the ascitic fluid.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782909 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Badshah A, Shaukat A Tags: Eur J Intern Med Source Type: journals

Progressive multifocal leukoencephalopathy - experimental options.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782910 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Rock C, Bergin C Tags: Eur J Intern Med Source Type: journals

Are colorectal adenomas associated with iron deficiency in hospitalized older patients?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19782911 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Joosten E, Vandewinckele H, Meeuwissen J, Hiele M Tags: Eur J Intern Med Source Type: journals

The role of tubular injury in diabetic nephropathy.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article reviews these data and the light they throw on the role of renal tubules in the pathogenesis of diabetic nephropathy. PMID: 19782912 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Magri CJ, Fava S Tags: Eur J Intern Med Source Type: journals

Evaluation of proteinuria and GFR to diagnose and classify kidney disease: systematic review and proof of concept.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic kidney disease is often not associated with significant symptoms or abnormalities in common laboratory test results. Diagnosis is supposedly facilitated by calculating the glomerular filtration rate (GFR) from serum creatinine. A reference range GFR, however, does not exclude renal disease, because renal disease causes the subsequent decrease of renal function. Thorough analysis of proteinuria, however, requires a profound knowledge of the renal handling of the different marker proteins of glomerular and tubular origin. This paper summarizes the scientific basis, explains the diagnostic rationale and proves the...
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Regeniter A, Freidank H, Dickenmann M, Boesken WH, Siede WH Tags: Eur J Intern Med Source Type: journals

A new era for anticoagulants.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Selective inhibitors of specific coagulation factors represent a new class of antithrombotic agents, designed to overcome the limitations of traditional anticoagulants. Available clinical studies indicate that the most promising new anticoagulants are those selectively targeting factor Xa and thrombin. Typically, the standard steps for clinical evaluation of new anticoagulants are thromboprophylaxis in high risk orthopedic surgery, followed by treatment of established venous thromboembolism, nonvalvular atrial fibrillation and acute coronary syndromes. These agents - that have the potential to be more effective and eas...
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Franchini M, Mannucci PM Tags: Eur J Intern Med Source Type: journals

Common ground: the overlap between Endocrinology and Rheumatology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A number of medical specialities have witnessed a dramatic change in the provision of in patient care over the last decade. Work has moved into outpatient and Day Unit settings and, more recently, into the community. This has led to the amalgamation of speciality based beds with the perceived threat of loss of independence and potential reduction in training opportunities. In reality, our experience of a combined inpatient ward for Rheumatology and Endocrinology patients has been positive, with increased awareness of the coexistence of certain disorders and a resulting enhanced approach to the delivery of patient care,...
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Bracewell C, Vila J, Narayanan K, Kelly C Tags: Eur J Intern Med Source Type: journals

Placebo therapy in Crohn's disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The knowledge of the outcome among patients receiving placebo is important for evaluating the response to therapy, for evaluating the natural history of a disease and for calculating the sample size for future clinical trials. In Crohn's disease placebo has been used in therapeutic trials in every relevant setting: active disease, prevention of relapse after induced medical remission and after surgery and fistulising disease. The analysis of the placebo response shows that in every setting there is a high heterogeneity demonstrating mainly that the selection of patients is not often homogeneous and that the outcome cri...
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Renna S, Orlando A, Mocciaro F, Cottone M Tags: Eur J Intern Med Source Type: journals

Chlamydophila pneumoniae infection and COPD: more evidence for lack of evidence?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chlamydophila pneumoniae has been recognized as a common cause of respiratory tract infections affecting all age groups. The organism has been implicated as an infectious trigger for acute exacerbations of COPD. Moreover, the intracellular existence of this pathogen and the ability to cause chronic respiratory infections have led to a number of studies that investigated its possible association with disease development. The present paper examines and discusses the possible association of acute C. pneumoniae infection in episodes of acute exacerbation of COPD. It also reviews the existing evidence of chronic C. pneumoni...
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Papaetis GS, Anastasakou E, Orphanidou D Tags: Eur J Intern Med Source Type: journals

Secondary stroke prevention in the elderly: new evidence in hypertension and hyperlipidemia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recurrent stroke is a major public health concern, occurring in approximately one third of stroke survivors within 5 years. Besides, the overall aging of the developed countries population and the improved survival of patients with stroke have created a large population of older adults in need of secondary stroke prevention. Thus, at present, more than 5% of individuals 65 to 74 years old and more than 10% of those 75 and older have had a prior stroke. An age bias exists in the prescription of important secondary-preventive therapies in the elderly. Knowledge of the evidence behind the secondary prevention strategies c...
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Castilla-Guerra L, Fernández-Moreno Mdel C, Alvarez-Suero J Tags: Eur J Intern Med Source Type: journals

Implantable cardioverter defibrillator: what a hospital practitioner needs to know.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The implantable cardioverter defibrillator (ICD) has undergone a remarkable transformation in the last three decades, both in generator size and functionality. This, coupled with improvements in lead design, allows the simplicity of defibrillator implantation to approach that of pacemakers, with outpatient placement now feasible. Nowadays, the majority of new ICD implants are performed on primary prevention grounds with device longevity of more than 7 years. In this article, we will concisely explain the evolution of this treatment, the implantation technique, arrhythmia detection and patient follow-up. In addition, we...
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Albouaini K, Mudawi T, Pyatt JR, Wright DJ Tags: Eur J Intern Med Source Type: journals

A prospective study of the management of non-massive pulmonary embolism in the home.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Patients with stable non-massive pulmonary embolism may be safely treated under conditions of home hospitalization. PMID: 19782920 [PubMed - in process] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - September 30, 2009 Category: Internal Medicine Authors: Rodríguez-Cerrillo M, Alvarez-Arcaya A, Fernández-Díaz E, Fernández-Cruz A Tags: Eur J Intern Med Source Type: journals