Obinutuzumab, a new anti ‐CD20 antibody, and chlorambucil are active and effective in anti‐myelin‐associated glycoprotein antibody polyneuropathy
ConclusionsIn our patients, obinutuzumab was effective as a first ‐line treatment of anti‐MAG antibody polyneuropathy. CLL might have had a role in the response to therapy, but the associations might be considered in future trials. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 27, 2018 Category: Neurology Authors: C. Briani,
A. Visentin,
A. Salvalaggio,
M. Cacciavillani,
L. Trentin Tags: Short Communication Source Type: research
Safety of urgent endarterectomy in acute non ‐disabling stroke patients with symptomatic carotid artery stenosis: an international multicenter study
ConclusionsOur findings highlight that urgent CEA performed within two days from the index event is related to a non ‐significant increase in the risk of peri‐procedural stroke. The safety of urgent CEA requires further evaluation in larger datasets.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 25, 2018 Category: Neurology Authors: Andromachi Roussopoulou,
Georgios Tsivgoulis,
Christos Krogias,
Andreas Lazaris,
Konstantinos Moulakakis,
George S. Georgiadis,
Robert Mikulik,
John D. Kakisis,
Christina Zompola,
Simon Faissner,
Maria Chondrogianni,
Chrissoula Liantinioti,
Th Tags: Original Article Source Type: research
High ‐frequency rTMS and iTBS for spasticity management in secondary‐progressive multiple sclerosis
ConclusionsThe results show that HF ‐rTMS and iTBS significantly reduce spasticity measured by MAS, in contrast to sham stimulation. Some evidence was found in favor of a longer‐lasting effect of iTBS on SESS, and of a reduction in pain and fatigue after HF‐rTMS.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 25, 2018 Category: Neurology Authors: Julia Korzhova,
Ilya Bakulin,
Dmitry Sinitsyn,
Alexandra Poydasheva,
Natalia Suponeva,
Maria Zakharova,
Michael Piradov Tags: Original Article Source Type: research
A randomized controlled trial of a walking training with simultaneous cognitive demand (dual ‐task) in chronic stroke
ConclusionsWalking with specific additional cognitive distraction (dual ‐task training) might increase activity more over 12 weeks, but the data are not conclusive. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 25, 2018 Category: Neurology Authors: D. Meester,
E. Al ‐Yahya,
A. Dennis,
J. Collett,
D. T. Wade,
M. Ovington,
F. Liu,
A. Meaney,
J. Cockburn,
H. Johansen‐Berg,
H. Dawes Tags: Original Article Source Type: research
“Stroke‐like” events after brain radiotherapy: a large series with long‐term follow‐up
Conclusions“Stroke‐like” events related to brain irradiation may be associated with permanent sequelae. Steroids are often administered on empirical grounds, as they are thought to accelerate recovery. Relapses are common, highlighting the need to elaborate adequate prevention strategies.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 24, 2018 Category: Neurology Authors: Anna Luisa Di Stefano,
Giulia Berzero,
Fran çois Ducray,
Marica Eoli,
Anna Pichiecchio,
Lisa Maria Farina,
Valeria Cuccarini,
Marta Claudia Brunelli,
Luca Diamanti,
Stéphanie Condette Auliac,
Andrea Salmaggi,
Antonio Silvani,
Bruno Giometto, Tags: Original Article Source Type: research
Compliance with international guidelines for chronic inflammatory neuropathies
This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 24, 2018 Category: Neurology Authors: Yusuf A. Rajabally,
Peter van den Bergh,
The European Study Group on Guidelines for Neuropathy Tags: Editorials Source Type: research
A study of the NR4A family gene expression in Multiple Sclerosis patients treated with Fingolimod
ConclusionsAn involvement of the NR4A family in MS pathogenesis and a role of Fingolimod in the recovery from NR4A2 deficit can be hypothesized based on our data.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 22, 2018 Category: Neurology Authors: Francesca Montarolo,
Simona Perga,
Serena Martire,
Federica Brescia,
Marzia Caldano,
Marianna Lo Re,
Giancarlo Panzica,
Antonio Bertolotto Tags: Original Article Source Type: research
Donepezil for Gait and Falls in Mild Cognitive Impairment. A Randomized Controlled Trial
ConclusionsDonepezil treatment improved dual ‐task gait speed and DTC in elderly with MCI. Our results support the concept of reducing falls in MCI by targeting motor‐cognitive interface.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 22, 2018 Category: Neurology Authors: Manuel Montero ‐Odasso,
Mark Speechley,
Howard Chertkow,
Yanina Sarquis‐Adamson,
Jennie Wells,
Michael Borrie,
Leanne Vanderhaeghe,
GY Zou,
Sarah Fraser,
Louis Bherer,
Susan Muir‐Hunter Tags: Original Article Source Type: research
Is there still a role for intravenous thrombolysis in the era of mechanical thrombectomy in patients with acute intracranial large artery occlusions?
This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 22, 2018 Category: Neurology Authors: M Uyttenboogaart Tags: Editorials Source Type: research
Acute ischemic lesions are associated with cortical superficial siderosis in spontaneous intracerebral hemorrhage
ConclusionsDWI lesions are more frequently observed in patients with acute lobar ICH than in those with deep ICH. cSS severity and WMH extent are independent predictors for the presence of DWI lesions, suggesting that CAA may be involved in the pathogenesis of DWI lesions associated with acute ICH.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 22, 2018 Category: Neurology Authors: Paul Revel ‐Mouroz,
Alain Viguier,
Vanessa Cazzola,
Lionel Calviere,
Sofia Patsoura,
Vanessa Rousseau,
Agnès Sommet,
Jean François Albucher,
Christophe Cognard,
Jean Marc Olivot,
Fabrice Bonneville,
Nicolas Raposo Tags: Original Article Source Type: research
Levodopa/carbidopa intestinal gel infusion and weight loss in Parkinson's disease
ConclusionsWeight loss may occur in patients with PD undergoing LCIG in correlation with the percentage of the waking day spent with dyskinesia. Regardless of the extent of WL, the nutritional status correlated with higher LEDD, as well as with indices of disease progression, such as motor symptom severity and dysphagia. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 18, 2018 Category: Neurology Authors: M. Fabbri,
M. Zibetti,
L. Beccaria,
A. Merola,
A. Romagnolo,
E. Montanaro,
J. J. Ferreira,
S. Palermo,
L. Lopiano Tags: Original Article Source Type: research
Peri ‐lead edema after deep brain stimulation surgery for Parkinson's disease: a prospective magnetic resonance imaging study
ConclusionsPeri ‐electrode edema is a common, transient reaction to DBS lead placement and a convincing relation between edema and post‐operative clinical status is lacking. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 18, 2018 Category: Neurology Authors: L. Borellini,
G. Ardolino,
G. Carrabba,
M. Locatelli,
P. Rampini,
S. Sbaraini,
E. Scola,
S. Avignone,
F. Triulzi,
S. Barbieri,
F. Cogiamanian Tags: Original Article Source Type: research
Comparison of two high doses of oral methylprednisolone for multiple sclerosis relapses: a pilot, multicentre, randomized, double ‐blind, non‐inferiority trial
ConclusionsA lesser high ‐dose oral methylprednisolone regimen may not be inferior to the standard high dose in terms of clinical and radiological response. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 16, 2018 Category: Neurology Authors: J. V. Herv ás‐García,
L. Ramió‐Torrentà,
L. Brieva‐Ruiz,
J. Batllé‐Nadal,
E. Moral,
Y. Blanco,
A. Cano‐Orgaz,
S. Presas‐Rodríguez,
F. Torres,
J. Capellades,
C. Ramo‐Tello Tags: Original Article Source Type: research
A cost –utility analysis of decompressive hemicraniectomy versus medical treatment in the management of space‐occupying brain oedema post middle cerebral artery infarction
DiscussionThis is above the National Institute for Health and Care Excellence (NICE) ‘cost‐effective’ threshold of £20 000–£30 000 per QALY, but lower mortality rates associated with the surgical alternative raises ethical considerations for healthcare providers in the UK. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 15, 2018 Category: Neurology Authors: A. Bhattacharyya,
A. Tahir,
A. Chandrashekar,
S. Vasisht,
L. Stinson,
J. Omatseye Tags: Original Article Source Type: research
Diagnostic usefulness of plexus MRI in chronic inflammatory demyelinating polyradiculopathy without electrodiagnostic criteria of demyelination
ConclusionsOur observations suggest that plexus MRI makes a valuable contribution to the diagnosis of CIDP ‐ND patients. Further studies are needed to investigate inter‐rater reliability of clinical and imaging criteria of CIDP in these patients, and the impact on outcomes.This article is protected by copyright. All rights reserved. (Source: European Journal of Neurology)
Source: European Journal of Neurology - November 15, 2018 Category: Neurology Authors: Guillaume Fargeot,
Karine Viala,
Marie Theaudin,
Marc ‐Antoine Labeyrie,
Raquel Costa,
Jean Marc Léger,
David Adams,
Christophe Vandendries,
Celine Labeyrie Tags: Original Article Source Type: research
