European Journal of Nuclear Medicine and Molecular Imaging
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1137 records returned
New reconstruction algorithm allows shortened acquisition time for myocardial perfusion SPECT
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Conclusion With the new IR algorithm, SPECT MPI can be acquired at half of the scan time without compromising image quality, resulting
in an excellent agreement with FULL time scans regarding to uptake and clinical conclusion.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1300-0Authors
Ines Valenta, University Hospital Zurich Cardiac Imaging Raemistrasse 100 8091 Zurich SwitzerlandValerie Treyer, University Hospital Zurich Cardiac Imaging Raemistrasse 100 8091 Zurich SwitzerlandLars Husmann, University Hospital Zurich Cardiac Imaging Raemistrasse 100 8091 Zurich Switzerlan...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 18, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Radiation burden in myocardial imaging: an old concern in the new age of hi-tech, hybrid imaging
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Content Type Journal ArticleCategory Focus onDOI 10.1007/s00259-009-1309-4Authors
Giovanni Lucignani, University of Milan Department of Biomedical Sciences and Technologies and Center of Molecular and Cellular Imaging (IMAGO) Milan Italy
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 18, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Erratum to: FDG PET as a prognostic predictor in the early post-therapeutic evaluation for unresectable hepatocellular carcinoma
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Content Type Journal ArticleCategory ErratumDOI 10.1007/s00259-009-1320-9Authors
Tatsuya Higashi, Shiga Medical Center Research Institute 5-4-30 Moriyama Moriyama City Shiga 524-8524 JapanEtsuro Hatano, Kyoto University Graduate School of Medicine Department of Gastroenterological Surgery 54 Kawahara-cho, Shogoin Sakyo-ku Kyoto 606-8507 JapanIwao Ikai, Kyoto University Graduate School of Medicine Department of Gastroenterological Surgery 54 Kawahara-cho, Shogoin Sakyo-ku Kyoto 606-8507 JapanRyuichi Nishii, Shiga Medical Center Research Institute 5-4-30 Moriyama Moriyama City Shiga 524-8524 JapanYuji Nakamoto, Kyoto Uni...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 18, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Detection of hypoxia in microscopic tumors using 131I-labeled iodo-azomycin galactopyranoside (131I-IAZGP) digital autoradiography
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Conclusion
131I-IAZGP can detect hypoxia in microscopic tumors. Microscopic tumors are useful models for the validation of hypoxia radiotracers,
and digital autoradiography is an appropriate technique for studying the distribution of hypoxia radiotracers in microscopic
tumors.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1310-yAuthors
Xiao-Feng Li, Memorial Sloan-Kettering Cancer Center Department of Medical Physics New York NY USAXiaorong Sun, Memorial Sloan-Kettering Cancer Center Department of Medical Physics New York NY USAYuanyuan Ma, Memorial Sloan-Kettering Canc...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 18, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Multimodality imaging in Europe: a survey by the European Association of Nuclear Medicine (EANM) and the European Society of Radiology (ESR)
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Conclusion The results of this survey show that there is wide heterogeneity in the current practice of multimodality imaging in Europe.
This situation may limit the full potential and integration of multimodality imaging within the clinical arena. There is a
strong desire within both specialties for the development of interdisciplinary training to address some of these issues.
Content Type Journal ArticleCategory Special ContributionDOI 10.1007/s00259-009-1250-6Authors
Alberto Cuocolo, University of Naples Federico II and SDN Foundation, Institute of Diagnostic and Nuclear Development Department of Bi...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
PET aerosol lung scintigraphy using Galligas
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Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00259-009-1304-9Authors
Jörg Kotzerke, Technische Universität Dresden Klinik und Poliklinik für Nuklearmedizin Dresden GermanyMichael Andreeff, Technische Universität Dresden Klinik und Poliklinik für Nuklearmedizin Dresden GermanyGerd Wunderlich, Technische Universität Dresden Klinik und Poliklinik für Nuklearmedizin Dresden Germany
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Clinical impact of 11C-methionine PET on expected management of patients with brain neoplasm
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Conclusion
11C-MET PET can provide useful information in initial diagnosis and differentiating tumor recurrence from radiation necrosis.
The intended management was changed in half of the scans. Since a few cases did not receive the requisite treatment due to
false-negative results of 11C-MET PET, management decision should be made carefully, especially in the case of a negative scan.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1302-yAuthors
Tomohiko Yamane, Institution of Biomedical Research and Innovation Division of Molecular imaging 2-2 Minatojima-Minamimachi, Chu...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Revisiting the prognostic value of preoperative 18F-fluoro-2-deoxyglucose (18F-FDG) positron emission tomography (PET) in early-stage (I & II) non-small cell lung cancers (NSCLC)
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Conclusion Each doubling of SUVmax as determined by preoperative PET is associated with a 1.28-fold increase in hazard of death in early-stage (I & II) NSCLC.
Preoperative SUVmax is not an independent predictor of overall survival.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1291-xAuthors
Mohit Agarwal, Oakland University William Beaumont School of Medicine Hospital Department of Internal Medicine 3601 W 13 Mile Rd Royal Oak MI 48073-6769 USAGovinda Brahmanday, Oakland University William Beaumont School of Medicine Hospital Department of Internal Medicine 3601 W 13 Mile ...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Radiobiological effects of hypoxia-dependent uptake of 64Cu-ATSM: enhanced DNA damage and cytotoxicity in hypoxic cells
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Conclusion The results support a model in which hypoxia-enhanced uptake of radiotoxic 64Cu induces sufficient DNA damage and toxicity to overcome the documented radioresistance in hypoxic MCF-7 cells. This suggests
that 64Cu-ATSM and related complexes have potential for targeted radionuclide therapy of hypoxic tumours.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1305-8Authors
Amanda J. Weeks, University of Kent School of Biosciences Canterbury Kent CT2 7NJ UKRowena L. Paul, Rayne Institute, St Thomas’ Hospital Division of Imaging Sciences, King’s College London Londo...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
FDG PET and PET/CT: EANM procedure guidelines for tumour PET imaging: version 1.0
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Abstract The aim of this guideline is to provide a minimum standard for the acquisition and interpretation of PET and PET/CT scans
with [18F]-fluorodeoxyglucose (FDG). This guideline will therefore address general information about [18F]-fluorodeoxyglucose
(FDG) positron emission tomography-computed tomography (PET/CT) and is provided to help the physician and physicist to assist
to carrying out, interpret, and document quantitative FDG PET/CT examinations, but will concentrate on the optimisation of
diagnostic quality and quantitative information.
Content Type Journal ArticleCategory GuidelinesDOI 10.100...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Motion correction and myocardial perfusion SPECT using manufacturer provided software. Does it affect image interpretation?
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Conclusion Motion-correction software must be used with caution when trying to optimize myocardial perfusion SPECT based on individual
analysis. Acquisition should be always repeated in cases with severe motion and in no or mild motion it seems preferable to
avoid correction.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1290-yAuthors
Teresa Massardo, University of Chile Clinical Hospital Nuclear Medicine Section, Department of Medicine Santos Dumont 999-1E, Independencia Santiago Chile 6531063Rodrigo Jaimovich, University of Chile Clinical Hospital Nuclear Medicine Secti...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Impaired myocardial blood flow reserve in subjects with metabolic syndrome analyzed using positron emission tomography and N-13 labeled ammonia
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Conclusions The results indicate that MFR was impaired in MS subjects, suggesting that an abnormal coronary microvascular response occurred
in these subjects. This abnormality may have been partially due to insulin resistance and hypertension.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1307-6Authors
Hiroki Teragawa, Hiroshima University Graduate School of Biomedical Sciences Department of Cardiovascular Medicine 1-2-3 Kasumi, Minami-ku Hiroshima 734-8551 JapanKoichi Morita, Hokkaido University Graduate School of Medicine Department of Nuclear Medicine Sapporo JapanHirok...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Kidney protection during peptide receptor radionuclide therapy with somatostatin analogues
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Abstract This review focuses on the present status of kidney protection during peptide receptor radionuclide therapy (PRRT) using radiolabelled
somatostatin analogues. This treatment modality for somatostatin receptor-positive tumours is limited by renal reabsorption
and retention of radiolabelled peptides resulting in dose-limiting high kidney radiation doses. Radiation nephropathy has
been described in several patients. Studies on the mechanism and localization demonstrate that renal uptake of radiolabelled
somatostatin analogues largely depends on the megalin/cubulin system in the proximal tubule cells. T...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 13, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Key role of nuclear medicine in bringing imaging biomarkers into clinical practice
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Content Type Journal ArticleCategory EditorialDOI 10.1007/s00259-009-1318-3Authors
Ignasi Carrió, Barcelona Spain
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 4, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Reduced parahippocampal and lateral temporal GABAA-[11C]flumazenil binding in major depression: preliminary results
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Conclusion The bilateral reduction in limbic parahippocampal and right temporal [11C]FMZ binding found in MDD indicates decreased GABAA-benzodiazepine receptor complex affinity and/or number. The inverse relationship between GABAA binding in the temporal lobe and HPA axis activity, suggests that HPA axis hyperactivity is partly due to reduced GABA-ergic
inhibition.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1292-9Authors
Ursula M. H. Klumpers, VU University Medical Center Department of Psychiatry Amsterdam The NetherlandsDick J. Veltman, VU University Medical Center Dep...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 4, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Bluth EI, Benson CB, Ralls PW, Siegel MJ (eds): Ultrasonography in vascular diseases. A practical approach to clinical problems (2nd edition)
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Content Type Journal ArticleCategory Book ReviewDOI 10.1007/s00259-009-1287-6Authors
Gianfranco Vallone, University Federico II Naples ItalyMassimo Vallone, University Federico II Naples Italy
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 31, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region
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Conclusion Subcortical white matter can be used as a reference region for quantitative analysis of [18F]FDDNP with the Logan method which allows more accurate and less biased binding estimates, but a population efflux rate constant
has to be determined a priori.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1293-8Authors
Koon-Pong Wong, David Geffen School of Medicine at UCLA Department of Molecular and Medical Pharmacology Rm. B2-085E CHS, 10833 Le Conte Avenue Los Angeles CA 90095 USAMirwais Wardak, David Geffen School of Medicine at UCLA Department of Molecular and Medi...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 31, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
FDG PET/CT in carcinoma of unknown primary
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This article will review the
use, diagnostic performance, and utility of FDG PET/CT in CUP and will discuss challenges and future considerations in the
diagnostic management of CUP.
Content Type Journal ArticleCategory Review ArticleDOI 10.1007/s00259-009-1295-6Authors
Thomas C. Kwee, University Medical Center Utrecht Department of Radiology Heidelberglaan 100 3584 CX Utrecht The NetherlandsSandip Basu, Hospital of the University of Pennsylvania Division of Nuclear Medicine, Department of Radiology Philadelphia PA USAGang Cheng, Hospital of the University of Pennsylvania Division of Nuclear Medicine, Department of R...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 31, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Early FDG-PET response–adapted risk stratification and further therapeutic decision-making in lymphoma: will this replace the established prognostic indices and be the standard-of-care in clinical management?
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Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00259-009-1296-5Authors
Sandip Basu, Tata Memorial Hospital Annexe Radiation Medicine Centre (BARC) Parel Bombay 400012 India
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 27, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Clinical value of 18F-fluorodihydroxyphenylalanine positron emission tomography/computed tomography (18F-DOPA PET/CT) for detecting pheochromocytoma
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Conclusion
18F-DOPA PET/CT more accurately diagnoses and localizes adrenal and extra-adrenal masses suspicious for PHEO than do 18F-DOPA PET or CT alone.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1294-7Authors
Markus Luster, University of Ulm Department of Nuclear Medicine Albert-Einstein-Allee 23 89081 Ulm GermanyWolfram Karges, RWTH Aachen Division of Endocrinology and Diabetes Aachen GermanyKatrin Zeich, University of Ulm Department of Nuclear Medicine Albert-Einstein-Allee 23 89081 Ulm GermanySandra Pauls, University of Ulm Department of Radiology Ulm GermanyFrede...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 27, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Human biodistribution and radiation dosimetry of 11C-(R)-PK11195, the prototypic PET ligand to image inflammation
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Conclusion Imaging of TSPO with PET using 11C-(R)-PK11195 is associated with modest radiation exposure, similar in magnitude to most other 11C-labelled PET tracers, suggesting feasibility of 11C-(R)-PK11195 imaging in clinical human studies involving multiple scans in the same subjects per year.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1298-3Authors
Jussi Hirvonen, University of Turku and Turku University Hospital Turku PET Centre P.O. Box 52 20521 Turku FinlandAnne Roivainen, University of Turku and Turku University Hospital Turku PET Centre P.O. Box 52 20521 Turku Fi...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 27, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
C. B. Benson and E. I. Bluth, Ultrasonography in obstetrics and gynecology. A practical approach, 2nd edition
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Content Type Journal ArticleCategory Book ReviewDOI 10.1007/s00259-009-1288-5Authors
Massimo Vallone, Naples ItalyGianfranco Vallone, Naples Italy
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 27, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Clinical features and 123I-FP-CIT SPECT imaging in drug-induced parkinsonism and Parkinson’s disease
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Conclusion DIP and PD are difficult to differentiate based on clinical signs. The precision of clinical diagnosis could be reliably enhanced
by 123I-FP-CIT SPECT imaging.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1289-4Authors
Francisco J. Diaz-Corrales, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla Unidad de Trastornos del Movimiento, Servicio de Neurología, Instituto de Biomedicina de Sevilla Seville SpainSalome Sanz-Viedma, Hospital Universitario Virgen del Rocio Unidad Diagnóstica de Medicina Nuclear Seville SpainDavid Garcia-Solis, Hospita...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 27, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Progress and challenges in neuroendocrine and neural crest tumours: molecular imaging and therapy
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Content Type Journal ArticleCategory Focus onDOI 10.1007/s00259-009-1286-7Authors
Giovanni Lucignani, University of Milan Department of Biomedical Sciences and Technologies and Center of Molecular and Cellular Imaging (IMAGO) Milan ItalyEmilio Bombardieri, Istituto Nazionale Tumori IRCCS Foundation Nuclear Medicine Division, Department of Diagnostic Imaging and Therapy Milan Italy
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 21, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
EANM procedure guidelines for brain neurotransmission SPECT using 123I-labelled dopamine transporter ligands, version 2
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Abstract These guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee (ENC).
The aim of the guidelines is to assist nuclear medicine practitioners when making recommendations, performing, interpreting,
and reporting the results of clinical dopamine transporter (DAT) single photon emission computed tomography (SPECT) studies
using 123I-labelled radiopharmaceuticals. The aim is to achieve a high-quality standard of DAT SPECT imaging, which will increase the
diagnostic impact of this technique in neurological practice. The present document is an update of t...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 16, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
EANM procedure guideline for brain perfusion SPECT using 99mTc-labelled radiopharmaceuticals, version 2
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Abstract These guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee (ENC).
The purpose of the guidelines is to assist nuclear medicine practitioners when making recommendations, performing, interpreting,
and reporting the results of brain perfusion single photon emission computed tomography (SPECT) studies using 99mTc-labelled radiopharmaceuticals. The aim is to achieve a high quality standard for brain perfusion SPECT imaging, which will
increase the diagnostic impact of this technique in clinical practice. The present document replaces a former versio...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 16, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
EANM procedure guidelines for PET brain imaging using [18F]FDG, version 2
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Abstract These guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee (ENC).
The purpose of the guidelines is to assist nuclear medicine practitioners in making recommendations, performing, interpreting,
and reporting the results of fluorine-18 fluoro-2-deoxyglucose ([18F]FDG) PET imaging of the brain. The aim is to help achieve a high standard of FDG imaging, which will increase the diagnostic
impact of this technique in neurological and psychiatric practice. The present document replaces a former version of the guidelines
that were published in 2002 [1...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 16, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
EANM procedure guidelines for brain neurotransmission SPECT/PET using dopamine D2 receptor ligands, version 2
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Abstract The guidelines summarize the current views of the European Association of Nuclear Medicine Neuroimaging Committee (ENC). The
aims of the guidelines are to assist nuclear medicine practitioners in making recommendations, performing, interpreting and
reporting the results of clinical dopamine D2 receptor SPECT or PET studies, and to achieve a high quality standard of dopamine
D2 receptor imaging, which will increase the impact of this technique in neurological practice.
The present document is an update of the first guidelines for SPECT using D2 receptor ligands labelled with 123I [1] and was guided...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 16, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
FDG PET as a prognostic predictor in the early post-therapeutic evaluation for unresectable hepatocellular carcinoma
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Conclusion The present study suggests that post-therapeutic PET performed within 1 month after non-operative therapy can be a good predictor
of overall survival in unresectable HCC patients, while pre-therapeutic evaluation including PET, tumour markers and clinical
staging may not be useful.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1284-9Authors
Tatsuya Higashi, Shiga Medical Center Research Institute 5-4-30, Moriyama Moriyama City Shiga 524-8524 JapanEtsuro Hatano, Kyoto University Graduate School of Medicine Department of Gastroenterological Surgery 54 Kawaha...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 16, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Imaging of EGFR expression in murine xenografts using site-specifically labelled anti-EGFR 111In-DOTA-ZEGFR:2377 Affibody molecule: aspect of the injected tracer amount
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Conclusion The 111In-DOTA-ZEGFR:2377 Affibody molecule is a promising tracer for radionuclide molecular imaging of EGFR expression in malignant tumours. Careful
optimization of protein dose is required for high-contrast imaging of EGFR expression in vivo.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1283-xAuthors
Vladimir Tolmachev, Uppsala University Unit of Biomedical Radiation Sciences, Rudbeck Laboratory 751 81 Uppsala SwedenDaniel Rosik, Affibody AB Bromma SwedenHelena Wållberg, Royal Institute of Technology School of Biotechnology Stockholm SwedenAnna Sjöberg, Aff...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 16, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Time-dependent changes in 18F-FDG activity in the thymus and bone marrow following combination chemotherapy in paediatric patients with lymphoma
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Conclusion Knowledge of the time-dependent changes in metabolic activity in the thymus and marrow is important to avoid misinterpretation
of increased 18F-FDG uptake as disease in the off-therapy setting.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1280-0Authors
Ingeborg Goethals, Ghent University Hospital Department of Nuclear Medicine, Polikliniek 7 De Pintelaan 185 9000 Ghent BelgiumPieter Hoste, Ghent University Hospital Department of Nuclear Medicine, Polikliniek 7 De Pintelaan 185 9000 Ghent BelgiumCiel De Vriendt, Ghent University Hospital Department of Nuclear Me...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 10, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Pre-therapy 18F-FDG PET quantitative parameters help in predicting the response to radioimmunotherapy in non-Hodgkin lymphoma
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Conclusions Our preliminary results indicate that pre-therapy 18F-FDG PET functional parameters such as SUVmax and TLG may help predicting more accurately response to single agent Y90 based
RIT.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1275-xAuthors
Thomas Cazaentre, CHU Lille Service de Médecine Nucléaire et Imagerie Fonctionnelle 59000 Lille FranceFranck Morschhauser, CHU Lille Service des Maladies du Sang 59000 Lille FranceMaximilien Vermandel, CHU Lille Service de Médecine Nucléaire et Imagerie Fonctionnelle 59000 Lille FranceNacim Betrouni, INSERM U703 59000 ...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 10, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Brain perfusion SPECT correlates with CSF biomarkers in Alzheimer’s disease
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Conclusion Our results suggest a strong correlation between T-tau and P-tau levels and decreased brain perfusion in regions typically
affected by neuropathological changes in AD.
Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00259-009-1285-8Authors
Marie-Odile Habert, UMR-S 678 Université Pierre et Marie Curie-Paris 6, INSERM 75013 Paris FranceLeonardo Cruz de Souza, CHU Pitié-Salpêtrière, AP-HP Research and Resource Memory Centre and INSERM U610 Paris 75013 FranceFoudil Lamari, CHU Pitié-Salpêtrière, AP-HP Department of Metabolic Biochemistry Paris 75013 FranceNelle Darag...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 10, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
First experience of hepatic radioembolization using microspheres labelled with yttrium-90 (TheraSphere): practical aspects concerning its implementation
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Conclusion Although sometimes technically difficult, the use of TheraSphere microspheres is a worthwhile therapeutic approach because
of the low level exposure of operators and the encouraging rate of response or stabilization. The use of SPECT/CT contributes
greatly to helping therapeutic planning, especially in the learning curve or when the angiographic procedure is difficult.
Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00259-009-1279-6Authors
Etienne Garin, Comprehensive Cancer Center Eugène Marquis Department of Nuclear Medicine Rennes FranceYan Rolland, Comprehensive Ca...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 10, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Biodistribution, toxicity and radiation dosimetry studies of the serotonin transporter radioligand 4-[18F]-ADAM in rats and monkeys
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Conclusion Toxicity studies in Sprague-Dawley rats and radiation dosimetry studies in Formosa Rock monkeys suggested that 4-[18F]-ADAM is safe for use in human PET imaging studies.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1281-zAuthors
Ya-Yao Huang, Tri-Service General Hospital PET Center, Department of Nuclear Medicine 325 Sec. 2, Cheng-Kung Rd., Neihu 114 Taipei TaiwanKuo-Hsing Ma, National Defense Medical Center Department of Biology and Anatomy Taipei TaiwanTa-Wei Tseng, Tri-Service General Hospital PET Center, Department of Nuclear Medicine 325 Sec. 2, Cheng-Kun...
Source: European Journal of Nuclear Medicine and Molecular Imaging - October 10, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
[18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging
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Conclusion [18F]F15599 is a radiofluorinated agonist presenting interesting characteristics for probing in vitro and in vivo the high-affinity
states of the 5-HT1A receptors. Its differential labelling of 5-HT1A receptors in vitro and in vivo may result from its reported preferential interaction with receptors coupled to specific G-protein
subtypes.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1274-yAuthors
Laëtitia Lemoine, Université de Lyon Laboratory of Neuropharmacology EAC CNRS 5006 Lyon FranceMathieu Verdurand, Université de Lyon Laboratory of Neuropharmacology...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 29, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Dual-gated cardiac PET–Clinical feasibility study
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Conclusion The first clinical experiences using robust cardiac-respiratory dual gating are encouraging. Further testing in larger clinical
populations using tracers designed especially for plaque imaging is warranted.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1252-4Authors
Mika Teräs, Turku PET Centre PO BOX 52 20521 Turku FinlandTommi Kokki, Turku PET Centre PO BOX 52 20521 Turku FinlandNicolas Durand-Schaefer, General Electric Medical Systems Buc FranceTommi Noponen, Turku PET Centre PO BOX 52 20521 Turku FinlandMikko Pietilä, Turku University Hospital Departmen...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 29, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Increased uptake of 131I-MIBG after intra-arterial application in liver metastases of a neuroendocrine tumor
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Content Type Journal ArticleCategory Image of the MonthDOI 10.1007/s00259-009-1277-8Authors
Manuel Popp, Klinik und Poliklinik für Nuklearmedizin Fetscherstr. 74 01307 Dresden GermanyAnnette Strumpf, Klinik und Poliklinik für Nuklearmedizin Fetscherstr. 74 01307 Dresden GermanyKlaus Zöphel, Klinik und Poliklinik für Nuklearmedizin Fetscherstr. 74 01307 Dresden GermanyChristian Stroszczynski, Universitätsklinikum Institut und Poliklinik für Radiologische Diagnostik Dresden GermanyJörg Kotzerke, Klinik und Poliklinik für Nuklearmedizin Fetscherstr. 74 01307 Dresden Germany
Journal European Journal of Nucle...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 29, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Non-invasive assessment of coronary artery disease with CT coronary angiography and SPECT: a novel dose-saving fast-track algorithm
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Conclusion This new individualized low-dose algorithm allows rapid and accurate prediction of invasive CA findings and of treatment decision
with minimized radiation dose.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1273-zAuthors
Aju P. Pazhenkottil, University Hospital Zurich Cardiac Imaging Ramistrasse 100 CH-8091 Zurich SwitzerlandBernhard A. Herzog, University Hospital Zurich Cardiac Imaging Ramistrasse 100 CH-8091 Zurich SwitzerlandLars Husmann, University Hospital Zurich Cardiac Imaging Ramistrasse 100 CH-8091 Zurich SwitzerlandRonny R. Buechel, University Hospital...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 29, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Joint practice guidelines for radionuclide lymphoscintigraphy for sentinel node localization in oral/oropharyngeal squamous cell carcinoma
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This article was designed to outline the current best practice guidelines for the provision of
SNB in patients with early-stage OSCC, and to provide a framework for the currently evolving recommendations for its use.
These guidelines were prepared by a multidisciplinary surgical/nuclear medicine/pathology expert panel under the joint auspices
of the European Association of Nuclear Medicine (EANM) Oncology Committee and the Sentinel European Node Trial Committee.
Content Type Journal ArticleCategory GuidelinesDOI 10.1007/s00259-009-1248-0Authors
Lee W. T. Alkureishi, University of Chicago Medical Center Department o...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 28, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Molecular imaging of rheumatoid arthritis by radiolabelled monoclonal antibodies: new imaging strategies to guide molecular therapies
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This article reviews the use
of radiolabelled mAbs in the study of RA with particular emphasis on the use of different radiolabelled monoclonal antibodies
for therapy decision-making and follow-up.
Content Type Journal ArticleCategory Review ArticleDOI 10.1007/s00259-009-1272-0Authors
G. Malviya, University Medical Centre Groningen, University of Groningen Department of Nuclear Medicine and Molecular Imaging Groningen The NetherlandsF. Conti, “Sapienza” University of Rome Rheumatology Unit, I Faculty of Medicine and Surgery Rome ItalyM. Chianelli, University Medical Centre Groningen, University of Groningen Depa...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 24, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
EANM Springer Prizes 2009 Awarded
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Content Type Journal ArticleCategory Society communicationsDOI 10.1007/s00259-009-1257-z
Journal European Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 24, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Tumoural denervation of the nigrostriatal pathway
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Content Type Journal ArticleCategory Image of the MonthDOI 10.1007/s00259-009-1278-7Authors
Martin Victor Añaños, Hospital Universitario Miguel Servet Department of Nuclear Medicine P. Isabel la Católica 1-3. 50009 Zaragoza SpainTeresa Baringo, Hospital Universitario Miguel Servet Department of Nuclear Medicine P. Isabel la Católica 1-3. 50009 Zaragoza SpainPaola Lievano, Hospital Universitario Miguel Servet Department of Nuclear Medicine P. Isabel la Católica 1-3. 50009 Zaragoza SpainLeticia De la Cueva, Hospital Universitario Miguel Servet Department of Nuclear Medicine P. Isabel la Católica 1-3. 50009 Zaragoza...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 24, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Coronary calcium score scans for attenuation correction of quantitative PET/CT 13N-ammonia myocardial perfusion imaging
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Conclusion Use of attenuation maps from CCS scans allows accurate quantitative MBF and CFR assessment with 13N-ammonia PET/CT.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1271-1Authors
Nina Burkhard, University Hospital Zurich Cardiac Imaging NUK C42, Ramistrasse 100 8091 Zurich SwitzerlandBernhard A. Herzog, University Hospital Zurich Cardiac Imaging NUK C42, Ramistrasse 100 8091 Zurich SwitzerlandLars Husmann, University Hospital Zurich Cardiac Imaging NUK C42, Ramistrasse 100 8091 Zurich SwitzerlandAju P. Pazhenkottil, University Hospital Zurich Cardiac Imaging NUK C42...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 24, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
186Re-maSGS-ZHER2:342, a potential Affibody conjugate for systemic therapy of HER2-expressing tumours
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Conclusion Optimization of chelators improves biodistribution properties of rhenium-labelled small scaffold proteins and enables selection
of promising radiotherapeutic agents based on the Affibody molecule.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1268-9Authors
Anna Orlova, Uppsala University Division of Biomedical Radiation Sciences, Rudbeck Laboratory 751 81 Uppsala SwedenThuy A. Tran, Uppsala University Division of Biomedical Radiation Sciences, Rudbeck Laboratory 751 81 Uppsala SwedenTorun Ekblad, Royal Institute of Technology School of Biotechnology, Division of...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 21, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging
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Conclusions The novel Df-Bz-NCS BFC allows efficient and easy preparation of optimally performing 89Zr-labeled mAbs, facilitating further exploration of 89Zr-immuno-PET as an imaging tool.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1263-1Authors
Lars R. Perk, VU University Medical Center Department of Otolaryngology/Head and Neck Surgery De Boelelaan 1117 PO Box 7057 1007 MB Amsterdam The NetherlandsMaria J. W. D. Vosjan, VU University Medical Center Department of Otolaryngology/Head and Neck Surgery De Boelelaan 1117 PO Box 7057 1007 MB Amsterdam The NetherlandsGerard...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 18, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Potential impact of 68Ga-DOTATOC PET/CT on stereotactic radiotherapy planning of meningiomas
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Conclusion
68Ga-DOTATOC-PET enables delineation of SR-positive meningiomas and delivers additional information to both CT and MRI regarding
the planning of stereotactic radiotherapy. The acquisition on a PET/CT scanner helps to estimate the relation of PET findings
to anatomical structures and is especially useful for detection of osseous infiltration. 68Ga-DOTATOC-PET also allows detection of additional lesions in patients with multiple meningiomas.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1270-2Authors
Fonyuy Nyuyki, Charité-Universitätsmedizin Berlin Departmen...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 18, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
A dose-effect correlation for radioiodine ablation in differentiated thyroid cancer
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Conclusions A successful ablation is strongly dependent on the absorbed dose to the thyroid remnant. Dosimetry-based personalized treatment
can prevent both sub-optimal administrations, which entails further radioiodine therapy, and excessive administration of radioactivity,
which increases the potential for radiation toxicity.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1261-3Authors
Glenn D. Flux, Royal Marsden NHS Foundation Trust Department of Physics Downs Road Sutton Surrey SM2 5PT UKMasud Haq, Royal Marsden NHS Foundation Trust Thyroid Unit Downs Road Sutton Surr...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 17, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Recombinant human TSH and ablation of post-surgical thyroid remnants in differentiated thyroid cancer: the effect of pre-treatment with furosemide and furosemide plus lithium
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Conclusion rhTSH is highly effective for post-surgical thyroid remnant ablation in low-risk cancer patients using the low 30-mCi dose
protocol combined with the short 4-day withdrawal of L-T4. Moreover, in these patients the pre-treatment with furosemide seems
to play an important role to further improve the outcome of ablation by reducing the iodine pool.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1254-2Authors
Daniele Barbaro, General Hospital of Livorno Endocrinology Unit Livorno ItalyMariano Grosso, University of Pisa Medical School Regional Center of Nuclear Medic...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 17, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
Intraoperative avidination for radionuclide treatment as a radiotherapy boost in breast cancer: results of a phase II study with 90Y-labeled biotin
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Conclusions IART plus reduced EBRT can accelerate irradiation after conservative breast surgery.
Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-009-1260-4Authors
Giovanni Paganelli, European Institute of Oncology Division of Nuclear Medicine Via Ripamonti 435 20141 Milan ItalyConcetta De Cicco, European Institute of Oncology Division of Nuclear Medicine Via Ripamonti 435 20141 Milan ItalyMahila E. Ferrari, European Institute of Oncology Division of Medical Physics Via Ripamonti 435 Milan ItalyGiuseppe Carbone, European Institute of Oncology Division of Nuclear Medicine Via Ripam...
Source: European Journal of Nuclear Medicine and Molecular Imaging - September 17, 2009 Category: Radiology Tags: European Journal of Nuclear Medicine and Molecular Imaging Source Type: journals
