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Dose and time-dependent hypercholesterolemic effects of iodine excess via TRβ1-mediated down regulation of hepatic LDLr gene expressionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Present findings demonstrated dose- and time-dependent hypercholesterolemic effects of iodine excess. Furthermore, our data suggests that TRβ1-mediated down regulation of hepatic LDLr gene may play a critical role in iodine excess-induced hypercholesterolemic effects. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0081-3Authors Li-Na Zhao, Huazhong University of Science and Technology Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College 430030 Wuhan Hubei ChinaJian Xu, Shen Zhen Center for Chronic Disease Control 518100...
Source: European Journal of Nutrition - November 16, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Two prolamin peptides from durum wheat preclude celiac disease-specific T cell activation by gluten proteinsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The T cell reactivity elicited by PTP is precluded by both the 9-mer and the 10-mer sequence, suggesting that over-expression of these proteolytically stable peptides may result in a wheat flour with reduced toxicity for CD patients. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00394-009-0080-4Authors Massimo De Vincenzi, Istituto Superiore di Sanità Division of Food Safety and Veterinary Public Health Viale Regina Elena, 299 00161 Rome ItalyOlimpia Vincentini, Istituto Superiore di Sanità Division of Food Safety and Veterinary Public Health Viale Regina Elena, 299...
Source: European Journal of Nutrition - November 5, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Suppressive effects of the marine carotenoids, fucoxanthin and fucoxanthinol on triglyceride absorption in lymph duct-cannulated ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These results show that these two marine carotenoids inhibit lipase activity in the gastrointestinal lumen and suppress triglyceride absorption, and fucoxanthin was converted to fucoxanthinol in the intestine and released into the lymph. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0078-yAuthors Megumi Matsumoto, Hokkaido University Meiji Dairies Research Chair, Creative Research Initiative Sousei (CRIS) Kita-21, Nishi-10, Kita-ku Sapporo Hokkaido 001-0021 JapanMasashi Hosokawa, Hokkaido University Laboratory of Biofunctional Material Chemistry, Division o...
Source: European Journal of Nutrition - November 3, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Beta-glucan may play an important role in algae hypocholesterolemia effectEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00394-009-0079-xAuthors Jiezhong Chen, University of Wollongong School of Health Sciences Northfields Avenue NSW 2522 AustraliaXu-Feng Huang, University of Wollongong School of Health Sciences Northfields Avenue NSW 2522 Australia Journal European Journal of NutritionOnline ISSN 1436-6215Print ISSN 1436-6207 (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - November 3, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Decreased high-density lipoprotein cholesterol and insulin resistance were the most common criteria in 12- to 19-year-old adolescentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions High prevalence of MetS especially among overweight and obese adolescents is a serious health problem. Early identification of the syndrome would contribute greatly to the prevention of diabetes and cardiovascular diseases in youth. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0066-2Authors Nurten Budak, Erciyes University Department of Nutrition and Dietetics, Atatürk School of Health 38039 Kayseri TurkeyAhmet Öztürk, Erciyes University Department of Biostatistics, Medical Faculty 38039 Kayseri TurkeyMümtaz Mazicioglu, Erciyes University Department o...
Source: European Journal of Nutrition - October 30, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Long chain saturated fatty acids increase haptoglobin gene expression in C57BL/6J mice adipose tissue and 3T3-L1 cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The type of lipids in the diet can differently modulate the white adipose tissue gene expression of haptoglobin, and saturated fatty acids play a major role in promoting a pro-inflammatory environment. This response is fat pad specific and dependant on the duration of treatment. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0069-zAuthors Allain Amador Bueno, São Paulo Federal University Department of Physiology Campus São Paulo, Rua Botucatu, 862, Edifício de Ciências Biomédicas São Paulo SP BrazilLila Missae Oyama, São Paulo Federal University, Cam...
Source: European Journal of Nutrition - October 24, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Prevention of oxidative DNA damage in inner organs and lymphocytes of rats by green tea extractEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our results show that a dose of GTE, which is equivalent to consumption of 500 ml GT/p/day in humans protects lymphocytes and to a lesser extent inner organs against oxidative DNA damage, while no effect was seen with a lower dose corresponding to an uptake of 100 ml/p/day. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0068-0Authors Nina Kager, Medical University of Vienna Department of Medicine I, Institute of Cancer Research Borschkegasse 8a 1090 Vienna AustriaFranziska Ferk, Medical University of Vienna Department of Medicine I, Institute of ...
Source: European Journal of Nutrition - October 22, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Dietary intake and plasma concentrations of PUFA and LC-PUFA in breastfed and formula fed infants under real-life conditionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Infants consuming present-day LC-PUFA-supplemented formula achieved plasma LC-PUFA concentrations similar to breastfed infants. In infants consuming non-LC-PUFA-supplemented formula, the favorable PUFA pattern of the formula may have supported n-3 LC-PUFA biosynthesis. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0067-1Authors Jana Schwartz, Rheinische Friedrich-Wilhelms-Universität Bonn Research Institute of Child Nutrition Dortmund Heinstück 11 44225 Dortmund GermanyClaudia Drossard, Rheinische Friedrich-Wilhelms-Universität Bonn Research Institute o...
Source: European Journal of Nutrition - October 22, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary IslandsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The T allele of the SNP might constitute a nutrigenetic factor increasing the susceptibility of LP subjects, especially women, to develop MS in the Canary Islands. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0058-2Authors Ricardo Almon, Örebro University Family Medicine Research Centre, School of Health and Medical Sciences Box 1613 701 16 Örebro SwedenEva E. Álvarez-Leon, University of Las Palmas de Gran Canaria Department of Clinical Sciences, Faculty of Health Sciences Canary Islands SpainPeter Engfeldt, Örebro University Family Medicine Research ...
Source: European Journal of Nutrition - October 21, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Effect of beer consumption on levels of complex I and complex IV liver and heart mitochondrial enzymes and coenzymes Q9 and Q10 in adriamycin-treated ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These results indicate that alcohol-free beer prevents adriamycin-induced damage to mitochondrial chain components and, therefore, helps to prevent mitochondrial dysfunction. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0064-4Authors Victoria Valls-Belles, Universidad de Valencia Departamento de Pediatría, Ginecología y Obstetricia. Facultad de Medicina Valencia SpainCarmen Torres, Universidad de Valencia Departamento de Pediatría, Ginecología y Obstetricia. Facultad de Medicina Valencia SpainPilar Muñiz, Universidad de Burgos Departamento de Biotecn...
Source: European Journal of Nutrition - October 20, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Effect of probiotic supplementation on immunoglobulins, isoagglutinins and antibody response in children of low socio-economic statusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Supplementation of standard fermented milk with additional probiotics was not of benefit. The high natural rate of early microbial exposure in infants and children from a population of low socio-economic status living in a “less hygienic environment” may account for the absence of an additional immune-stimulating effect by supplementary probiotics. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0063-5Authors Néstor Pérez, Hospital de Niños de La Plata, Comisión de Investigaciones Científicas de la Provincia de Buenos Aires (CICPBA) Unidad de Inmun...
Source: European Journal of Nutrition - October 16, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Soybean whey enhance mineral balance and caecal fermentation in ratsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Background Soybean whey, a by-product of tofu manufacturing, is currently discarded by the food industry. However, it contains valuable compounds such as non-digestible oligosaccharides (NDO), which promote the growth of beneficial lactic acid bacteria in the colon, and are therefore recognized as prebiotics. Acidic fermentation of NDO in the caecum appears to be related with an increase in mineral absorption. Aim of the study To evaluate the effect of consuming soybean whey containing galacto-oligosaccharides (GOS) on mineral absorption and caecal fermentation in rats. Met...
Source: European Journal of Nutrition - October 15, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Alcohol consumption and the risk of coronary heart disease in postmenopausal women with diabetes: Women’s Health Initiative Observational StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Moderate alcohol consumption of postmenopausal women with type 2 diabetes may have a benefit on CHD similar to that seen in postmenopausal nondiabetic women. The potential risks of alcohol on noncardiac outcomes may need consideration when recommending alcohol to women with diabetes. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0065-3Authors Swapnil N. Rajpathak, Albert Einstein College of Medicine Department of Epidemiology and Population Health Bronx NY 10461 USAMathew S. Freiberg, University of Pittsburgh Departments of Medicine and Epidemiology Pitts...
Source: European Journal of Nutrition - October 13, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

The association between high plasma homocysteine levels and lower bone mineral density in Slovak women: the impact of vegetarian dietEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Homocysteine is one of the predictors of bone mineral density, and hyperhomocysteinemia is associated with lower bone mineral density. In healthy adults, homocysteine levels are dependent on age as well as on nutritional habits. Thus, elderly women on a vegetarian diet seem to be at higher risk of osteoporosis development than nonvegetarian women. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0059-1Authors Zora Krivošíková, Slovak Medical University Department of Clinical and Experimental Pharmacotherapy Limbová 12 833 03 Bratislava SlovakiaMarica Kraj...
Source: European Journal of Nutrition - October 7, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Effect of polyunsaturated fatty acids on the reactive oxygen and nitrogen species production by raw 264.7 macrophagesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion High concentrations of PUFAs of both ω-3 and ω-6 groups can inhibit ROS and RNS formation by stimulated macrophages. The expression of iNOS can also be inhibited. This effect, together with the absence of antioxidant activity and cytotoxic properties, indicates that PUFAs can participate in the regulation of enzymes responsible for reactive species production. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0057-3Authors Gabriela Ambrozova, Academy of Sciences of the Czech Republic Institute of Biophysics Kralovopolska 135 612 65 Brno Czech RepublicMichael...
Source: European Journal of Nutrition - September 29, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Astaxanthin suppresses scavenger receptor expression and matrix metalloproteinase activity in macrophagesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These results indicate that astaxanthin has inhibitory effects on macrophage activation, such as scavenger receptors up-regulation, MMPs activation, and pro-inflammatory cytokines secretion. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0056-4Authors Yoshimi Kishimoto, Ochanomizu University Institute of Environmental Science for Human Life 2-1-1 Otsuka, Bunkyo-ku Tokyo 112-8610 JapanMariko Tani, Ochanomizu University Institute of Environmental Science for Human Life 2-1-1 Otsuka, Bunkyo-ku Tokyo 112-8610 JapanHarumi Uto-Kondo, National Defense Medical Coll...
Source: European Journal of Nutrition - September 29, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Very high plant stanol intake and serum plant stanols and non-cholesterol sterolsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Serum plant stanol levels remained at comparable low levels as in studies with daily intake of 2–3 g, and were normalized in 4 weeks suggesting that daily intake of 8.8 g of plant stanols might not increase systemic availability of plant stanols, but reduces effectively serum cholesterol and plant sterol levels. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0055-5Authors Helena Gylling, University of Kuopio Department of Clinical Nutrition P.O. BOX 1627 70211 Kuopio FinlandMaarit Hallikainen, University of Kuopio Department of Clinical Nu...
Source: European Journal of Nutrition - September 24, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Predictors of adherence to a Mediterranean-type diet in the PREDIMED trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Some participant characteristics (marital status and baseline dietary habits) could contribute to predicting the likelihood of achieving dietary goals in interventions aimed to improve adherence to a MeDiet, and may be useful for promoting individualized long-term dietary changes and improving the effectiveness of dietary counseling. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0053-7Authors Itziar Zazpe, University of Navarra Department of Preventive Medicine and Public Health Pamplona SpainRamón Estruch, IDIBAPS, Hospital Clinic, University of Barcelo...
Source: European Journal of Nutrition - September 17, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Dietary sucrose intake is related to serum leptin concentration in overweight pregnant womenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Overweight-related elevation in serum leptin is associated with impaired regulation of glucose metabolism during pregnancy. The novel finding that dietary sucrose intake is related to serum leptin concentration is in line with the current dietary recommendations to overweight pregnant women with impaired glucose metabolism advising the lower intake of sucrose during pregnancy. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0052-8Authors Sanna Vähämiko, University of Turku Functional Foods Forum 20014 Turku FinlandErika Isolauri, Turku University Hospita...
Source: European Journal of Nutrition - September 3, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Naringenin enhances insulin-stimulated tyrosine phosphorylation and improves the cellular actions of insulin in a dietary model of metabolic syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Naringenin improves insulin signaling and sensitivity and thereby promotes the cellular actions of insulin in this model. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0054-6Authors Sriramajayam Kannappan, Annamalai University Department of Biochemistry and Biotechnology, Faculty of Science Annamalai Nagar 608002 Tamil Nadu IndiaCarani Venkatraman Anuradha, Annamalai University Department of Biochemistry and Biotechnology, Faculty of Science Annamalai Nagar 608002 Tamil Nadu India Journal European Journal of NutritionOnline ISSN 1436-6215Print ISSN 1...
Source: European Journal of Nutrition - September 3, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Arabinoxylan-oligosaccharides (AXOS) reduce preneoplastic lesions in the colon of rats treated with 1,2-dimethylhydrazine (DMH)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The present study shows that dietary intake of AXOS by rats reduces the occurrence of two types of preneoplastic lesions, thus suggesting a chemopreventive effect on colon carcinogenesis that should be confirmed in a long-term carcinogenesis experiment. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00394-009-0050-xAuthors Angelo Pietro Femia, University of Florence Department of Pharmacology Viale Pieraccini 6 50139 Florence ItalyMaddalena Salvadori, University of Florence Department of Pharmacology Viale Pieraccini 6 50139 Florence ItalyWillem F. Broekaert, Fugeia NV...
Source: European Journal of Nutrition - August 27, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Potential antitumor properties of a protein isolate obtained from the seeds of Amaranthus mantegazzianusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions we report a protein isolate from the seeds of Amaranthus mantegazzianus that exhibit potential antitumor properties and propose a putative mechanism of action. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0051-9Authors Daniel Alejandro Barrio, Universidad Nacional de La Plata Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CIDCA) 47 y 115 1900 La Plata ArgentinaMaría Cristina Añón, Universidad Nacional de La Plata Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CIDCA) 47 y 115 1900 La Plata Argentina ...
Source: European Journal of Nutrition - August 21, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Lupin protein compared to casein slightly lowered the concentration of LDL cholesterol in hypercholesterolemic subjects, without altering HDL cholesterol. No or minor effects of lupin protein were observed on circulating glucose, homocysteine and plasma amino acids. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0049-3Authors Kristin Weiße, Martin-Luther-University Halle-Wittenberg Institute of Agricultural and Nutritional Sciences Von-Danckelmann-Platz 2 06120 Halle (Saale) GermanyCorinna Brandsch, Martin-Luther-University Halle-Wittenberg Institute of A...
Source: European Journal of Nutrition - August 12, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Effect of water soluble vitamins on Zn transport of Caco-2 cells and their implications under oxidative stress conditionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Results for the first time demonstrate advantageous effects of NA and deleterious consequences of FA with no effect by AA on Zn transport, especially under OS. These observed changes in the transport of Zn seem to have an impact on OS markers. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0048-4Authors Rashmi Santosh Tupe, Agharkar Research Institute G.G. Agarkar Road Pune 411004 IndiaVaishali Vilas Agte, Agharkar Research Institute G.G. Agarkar Road Pune 411004 India Journal European Journal of NutritionOnline ISSN 1436-6215Print ISSN 1436-6207 (So...
Source: European Journal of Nutrition - August 12, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Serum lutein concentrations in healthy term infants fed human milk or infant formula with luteinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Breastfed infants have higher mean serum lutein concentrations than infants who consume formula unfortified with lutein. These data suggest approximately 4 times more lutein is needed in infant formula than in human milk to achieve similar serum lutein concentrations among breastfed and formula fed infants. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0047-5Authors Jodi Bettler, Wyeth Collegeville PA USAJ. Paul Zimmer, Wyeth Collegeville PA USAMartha Neuringer, Oregon Health and Science University Oregon National Primate Research Center, Section of ...
Source: European Journal of Nutrition - August 11, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Contribution of energy density and food quantity to short-term fluctuations of energy intake in normal weight and obese subjectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Small day-to-day changes of EI are due to increased meal quantities while greater fluctuations are also due to higher food ED. The present data suggest that modification of FQ by cognitive and sensory factors plays an important role in the variation of daily EI under real life conditions with no major difference between normal weight and obese subjects. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0046-6Authors Volker Schusdziarra, Technical University of Munich Else-Kröner-Fresenius Center of Nutritional Medicine Ismaninger Straße 22 81675 Munich Germa...
Source: European Journal of Nutrition - August 11, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Genistein and β-carotene enhance the growth-inhibitory effect of trichostatin A in A549 cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Genistein and β-carotene enhance the cell-growth-arrest effect of TSA on A549 cells. Genistein exerts its effect, at least partly, by increasing caspase-3 activity; whereas β-carotene may enhance TSA-induced cell death mainly through a caspase-3-independent pathway. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0044-8Authors Rong-Jen Shiau, Chienkao Technology University Department of Beauty Science Changhua Taiwan, ROCKai-Yong Chen, Chung Shan Medical University Institute of Nutritional Science No. 110 Sec 1 Jianguo N. Rd Taichung Taiwan, ROCYu-Der Wen...
Source: European Journal of Nutrition - July 29, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Purified black tea theaflavins and theaflavins/catechin supplements did not affect serum lipids in healthy individuals with mildly to moderately elevated cholesterol concentrationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In this human intervention study, no statistically significant LDL-c lowering effect was seen with either TFs alone or the TFs/catechins combination as compared to placebo. Based on these findings it cannot be concluded that tea flavonoids such as theaflavins and catechins are responsible for a putative cholesterol-lowering effect of black tea, at least not with the daily dose applied in the present study. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0045-7Authors Elke A. Trautwein, Unilever Research and Development Vlaardingen The NetherlandsYaping Du, ...
Source: European Journal of Nutrition - July 29, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Modulation of detoxification enzymes by watercress: in vitro and in vivo investigations in human peripheral blood cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The results indicate that WC is able to modulate the enzymes SOD and GPX in blood cells in vitro and in vivo, and suggest that the capacity of moderate intake of CV to induce detoxification is dependent in part on the GSTM1 genotype. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0039-5Authors Thomas Hofmann, Friedrich Schiller University Jena Department of Nutritional Toxicology, Institute of Nutrition Dornburger Str. 24 07743 Jena GermanyA. Kuhnert, Friedrich Schiller University Jena Department of Nutritional Toxicology, Institute of Nutrition Dornburger S...
Source: European Journal of Nutrition - July 28, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Advanced glycation end products strongly activate plateletsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The increase in surface activation marker and RAGE expression in platelets, resulting from concentrations of AGEs that occur in vivo after a meal or a drink as a source of exogenous AGEs, points to signaling mechanisms for food AGEs that could favor the precipitation of acute postprandial ischemic events. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0038-6Authors Thomas Gawlowski, Ruhr-University Bochum Heart and Diabetes Center NRW Georgstrasse 11 32545 Bad Oeynhausen GermanyBernd Stratmann, Ruhr-University Bochum Heart and Diabetes Center NRW Georgstra...
Source: European Journal of Nutrition - July 26, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Comparison of free fructose and glucose to sucrose in the ability to cause fatty liverEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Diets containing 30% of fructose either as free fructose and glucose, or as sucrose, induce metabolic syndrome, intrahepatic accumulation of uric acid and TGs, increased MCP-1 and TNF-α as well as fatty liver in rats. It will be relevant to determine clinically whether pharmacological reduction in uric acid levels might have a therapeutic advantage in the treatment of non-alcoholic fatty liver disease. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0042-xAuthors Laura G. Sánchez-Lozada, University of Florida Division of Nephrology, Hypertension and Tran...
Source: European Journal of Nutrition - July 24, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Complementary food with low (8%) or high (12%) meat content as source of dietary iron: a double-blinded randomized controlled trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Background To investigate whether a low meat content of complementary food as accepted by EU law increases the risk of well-nourished infants to develop iron deficiency during the complementary feeding period. Methods Term born, healthy infants were randomized into a ‘High Meat’ Group (HM, n = 48) receiving commercial baby jars with a meat content of 12% by weight (according to pediatric guidelines), and a ‘Low Meat’ Group (LM, n = 49) receiving meals as marketed (meat 8% by weight, the lowest level of EU law). Intervention was from 4 to 10 months of...
Source: European Journal of Nutrition - July 22, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Comment on “Effects of adipocyte-secreted factors on cell cycle progression in HT29 cells” published by Eur J NutrEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00394-009-0040-zAuthors Jiezhong Chen, University of Wollongong Illawarra Health and Medical Research Institute Northfields Avenue Wollongong NSW 2522 AustraliaXu-Feng Huang, University of Wollongong Illawarra Health and Medical Research Institute Northfields Avenue Wollongong NSW 2522 Australia Journal European Journal of NutritionOnline ISSN 1436-6215Print ISSN 1436-6207 (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - July 18, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Hepatic lipid metabolism response to dietary fatty acids is differently modulated by PPARα in male and female miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our data suggests estrogen to modulate the regulation of hepatic lipid metabolic pathway by dietary fatty acids. Besides, PPARα invalidation resulted in unexpected regulations by ALA of its known targets and was compensated partly in females, which was therefore less sensitive to the detrimental effects of a SFA-rich diet. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0037-7Authors Anne Morise, Université Paris Sud Laboratoire d’Endocrinologie de la Nutrition 91405 Orsay FranceCharles Thomas, Inserm U866, ENSBANA Laboratoire de Physiologie de la Nutri...
Source: European Journal of Nutrition - July 9, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Effects of galacto-oligosaccharide ingestion on the mucosa-associated mucins and sucrase activity in the small intestine of miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions These results suggest that, in BALB/c mice, 4-week GOS ingestion is able to increase the small intestinal mucosa-associated mucin content and enterocyte-associated sucrase activity without modifying villus height. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0036-8Authors Géraldine Leforestier, INRA, CRNH-IdF, UMR914 Nutrition Physiology and Ingestive Behavior 16 rue Claude Bernard 75005 Paris FranceAnne Blais, INRA, CRNH-IdF, UMR914 Nutrition Physiology and Ingestive Behavior 16 rue Claude Bernard 75005 Paris FranceFrançois Blachier, INRA, CRNH-IdF, UM...
Source: European Journal of Nutrition - July 6, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Food derived carbonyl compounds affect basal and stimulated secretion of interleukin-6 and -8 in Caco-2 cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion These results suggest a pro-inflammatory effect of G and MG at high concentrations in human intestinal cells by stimulating IL-8 and IL-6 cytokine levels. Effects of G and MG in combination with other cytokines may negatively affect inflammatory processes. Content Type Journal ArticleCategory Short ContributionDOI 10.1007/s00394-009-0035-9Authors Sabine Kuntz, University of Giessen Institute of Nutritional Science Wilhelmstrasse 20 35392 Giessen GermanySilvia Rudloff, University of Giessen Department of Pediatrics Feulgenstrasse 12 35392 Giessen GermanyJulia Ehl, University of Giessen Insti...
Source: European Journal of Nutrition - June 22, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

ADIPOQ gene polymorphism rs1501299 interacts with fibre intake to affect adiponectin concentration in children: the GENe–Diet Attica Investigation on childhood obesityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In the present study, the rs1501299 × fibre interaction was significantly associated with adiponectin levels; in specific, GG homozygotes exhibited higher adiponectin levels compared to T carriers under conditions of lower fibre intake. Content Type Journal ArticleCategory Short ContributionDOI 10.1007/s00394-009-0034-xAuthors Ioanna Ntalla, Harokopio University Department of Dietetics, Nutrition 70 El. Venizelou St. 17671 Athens GreeceGeorge Dedoussis, Harokopio University Department of Dietetics, Nutrition 70 El. Venizelou St. 17671 Athens GreeceMary Yannakoulia, Harokopio Univ...
Source: European Journal of Nutrition - June 19, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Lycopene isomerisation and storage in an in vitro model of murine hepatic stellate cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions This study identified a novel hepatic cell type able to store and isomerise lycopene. Liver can contribute to the serum and tissue equilibrium of cis/trans isomers of lycopene, and to participate in storage of lycopene under high extracellular concentration such as observed after the alimentary input. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0001-6Authors Anderson J. Teodoro, Universidade Federal do Rio de Janeiro Laboratório de Bioquímica Nutricional e de Alimentos, Instituto de Química Rio de Janeiro BrazilDaniel Perrone, Universidade Federal do...
Source: European Journal of Nutrition - June 17, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

The effect of fatty or lean fish intake on inflammatory gene expression in peripheral blood mononuclear cells of patients with coronary heart diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The intake of FF or LF diet did not alter the expression of inflammatory and endothelial function-related genes in PBMCs of patients with CHD. However, the decrease in AA:EPA ratio in serum lipids in the FF group may induce an anti-inflammatory response at mRNA levels in PBMCs. A LF diet might benefit endothelial function, possibly mediated by the changes in serum FA composition. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0033-yAuthors Vanessa D. F. de Mello, University of Kuopio Department of Clinical Nutrition/Food and Health Research Centre, School ...
Source: European Journal of Nutrition - June 9, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Ability of probiotic Lactobacillus casei DN 114001 to bind or/and metabolise heterocyclic aromatic amines in vitroEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Introduction Heterocyclic aromatic amines (HCA) are compounds with high mutagenic potential, formed when meat is cooked at high temperatures of 150–300 °C. These compounds contribute to development of colon and gastric cancer. Western diet provides a lot of HCA and influences the available substrates for the intestinal microbiota which can activate HCA to direct acting mutagens. On the other hand, lactic acid bacteria existing in the colon and ingested with food including probiotics, may exert an anti-carcinogenic action, but the mechanism is still poorly understood. Materials and me...
Source: European Journal of Nutrition - May 16, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Mitochondrial DNA deletions of blood lymphocytes as genetic markers of low folate-related mitochondrial genotoxicity in peripheral tissuesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our data demonstrate that accumulated mtDNA deletions of lymphocytes depended upon dietary folate deprivation. The accumulated mt deletions in lymphocytes closely reflected the mt genotoxicity in the peripheral tissues during folate deficiency. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0031-0Authors Yi-Fang Chou, Fu-Jen University Department of Nutritional Science Hsinchuang 242 Taipei County TaiwanRwei-Fen S. Huang, Fu-Jen University Department of Nutritional Science Hsinchuang 242 Taipei County Taiwan Journal European Journal of NutritionOnline ISSN 143...
Source: European Journal of Nutrition - May 13, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Chronic undernutrition alters renal active Na+ transport in young rats: potential hidden basis for pathophysiological alterations in adulthood?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions We conclude that early alterations in proximal tubule Na+ pumps, together with an abnormally augmented urinary Na+ excretion, might be the link between undernutrition and late renal dysfunction. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0032-zAuthors João H. Costa-Silva, Universidade Federal de Pernambuco Departamento de Fisiologia e Farmacologia Recife Pernambuco 50670-901 BrazilPaulo A. Silva, Universidade Federal do Rio de Janeiro Instituto de Biofísica Carlos Chagas Filho Rio de Janeiro RJ 21941-902 BrazilNadir Pedi, Universidade Federal de Pernam...
Source: European Journal of Nutrition - May 12, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Effect of CLA isomers and their mixture on aging C57Bl/6J miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In conclusion, the major CLA isomers have a distinct effect on fat mass, glucose, and insulin metabolism. The t10,c12 isomer was found to reduce the fat mass and to increase the lean mass but significantly contributed to increase insulin resistance and liver hypertrophy, whereas c9,t11 isomer prevented the insulin resistance. Between the two major CLA isomers, the t10,c12 was attributed to reduce fat mass whereas, c9,t11 improves the insulin sensitivity. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0029-7Authors Ganesh V. Halade, University of Texas Heal...
Source: European Journal of Nutrition - May 8, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Adipocyte fatty acid binding protein during refeeding of female patients with anorexia nervosaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The present results indicate that variation in A-FABP plasma levels reflect alterations in nutritional status in patients with anorexia nervosa. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0027-9Authors Julia Engl, Medical University Innsbruck Department of Internal Medicine I Anichstrasse 35 6020 Innsbruck AustriaAlexander Tschoner, Medical University Innsbruck Department of Internal Medicine I Anichstrasse 35 6020 Innsbruck AustriaMichael Willis, Medical University Innsbruck Division for Psychosomatic Medicine and Psychosocial Psychiatry, Department of ...
Source: European Journal of Nutrition - May 7, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Health-promoting substances and heavy metal content in tomatoes grown with different farming techniquesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory ErratumDOI 10.1007/s00394-009-0028-8Authors Filippo Rossi, Università Cattolica del Sacro Cuore Istituto di Scienze degli Alimenti e della, Nutrizione, Facoltà di Agraria Via Emilia Parmense 84 29100 Piacenza ItalyFrancesco Godani, PAREN srl Noceto (Parma) ItalyTerenzio Bertuzzi, Università Cattolica del Sacro Cuore Istituto di Scienze degli Alimenti e della, Nutrizione, Facoltà di Agraria Via Emilia Parmense 84 29100 Piacenza ItalyMarco Trevisan, Università Cattolica del Sacro Cuore Istituto di Chimica Agraria ed Ambientale, Facoltà di Agraria Piacenza ItalyFederico Ferrari, ...
Source: European Journal of Nutrition - May 6, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

The influence of dietary fibre source and gender on the postprandial glucose and lipid response in healthy subjectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Postprandial glucose, insulin and triglyceride concentrations are influenced by dietary fibre-rich meals, depending on fibre source, dose of soluble and total fibre and possibly gender. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0026-xAuthors Matilda Ulmius, Lund University Biomedical Nutrition, Pure and Applied Biochemistry, Centre for Chemistry and Chemical Engineering P.O. Box 124 221 00 Lund SwedenAnna Johansson, Lund University Biomedical Nutrition, Pure and Applied Biochemistry, Centre for Chemistry and Chemical Engineering P.O. Box 124 221 00 Lun...
Source: European Journal of Nutrition - May 5, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Association between GPx1 Pro198Leu polymorphism, GPx1 activity and plasma selenium concentration in humansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The findings of the present study provide evidence for the hypothesis based on in vitro studies which assumes that GPx1 Pro198Leu polymorphism has a functional significance for the human organism and that this functionality is associated with a different response of GPx1 activity to Se. They also point to the importance of the genetic background in the assessment of the Se status with the use of selenoprotein biomarkers such as GPx1 activity. Content Type Journal ArticleCategory Short ContributionDOI 10.1007/s00394-009-0023-0Authors E. Jablonska, Nofer Institute of Occupational Medicine De...
Source: European Journal of Nutrition - May 5, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Serum sterol responses to increasing plant sterol intake from natural foods in the Mediterranean dietEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Small amounts of phytosterols in natural foods appear to be bioactive in cholesterol lowering. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0024-zAuthors Verónica Escurriol, Hospital Clínic Lipid Clinic, Endocrinology and Nutrition Service, Institut d’Investigacions Biomèdiques Ausgust Pi Sunyer (IDIBAPS) C. Villarroel 170 08036 Barcelona SpainMontserrat Cofán, Hospital Clínic Lipid Clinic, Endocrinology and Nutrition Service, Institut d’Investigacions Biomèdiques Ausgust Pi Sunyer (IDIBAPS) C. Villarroel 170 08036 Barcelona SpainMercè Serra, Ho...
Source: European Journal of Nutrition - May 3, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

Hypocholesterolemic effect of Nostoc commune var. sphaeroides Kützing, an edible blue-green algaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions N. commune supplementation exerted a hypocholesterolemic effect in mice, largely in part, by reducing intestinal cholesterol absorption and promoting fecal neutral sterol excretion. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0025-yAuthors Heather E. Rasmussen, University of Nebraska Department of Nutrition and Health Sciences Lincoln NE 68583-0806 USAKara R. Blobaum, University of Nebraska Department of Nutrition and Health Sciences Lincoln NE 68583-0806 USAElliot D. Jesch, University of Nebraska Department of Nutrition and Health Sciences Lincoln NE ...
Source: European Journal of Nutrition - April 30, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

[6S]-5-Methyltetrahydrofolate enhances folate status in rats fed growing-up milkEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion We conclude that the natural diastereomer [6S]-5-CH3-H4folate may adequately serve as an alternative to folic acid for the folate fortification of infant foods. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0022-1Authors Darío Pérez-Conesa, Universidad de Murcia Nutrición y Bromatología, Facultad de Veterinaria Campus Universitario de Espinardo 30071 Murcia SpainJuan Francisco Haro-Vicente, Universidad de Murcia Nutrición y Bromatología, Facultad de Veterinaria Campus Universitario de Espinardo 30071 Murcia SpainFernando Romero Braquehais, Hero España...
Source: European Journal of Nutrition - April 23, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals