Self-esteem, depression, anxiety and sexual function in Mayer-Rokitansky-K üster-Hauser syndrome with neovagina: A case series
The Mayer-Rokitansky-K üster-Hauser (MRKH) syndrome is a rare congenital disorder which affects one out of 4000 to 5000 women [1]. Due to failed embryologic development of the Müllerian ducts, the uterus and vagina are absent in women with MRKH syndrome. Patients are usually diagnosed during adolescence because of the a bsence of menstruation [2] or when difficulties with vaginal intercourse or infertility are experienced [3,4]. MRKH syndrome is traditionally classified into two types: Type I (isolated) without other malformations, Type II (atypical) includes renal and adnexal malformations and Müllerian agenesis, renal...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 22, 2024 Category: OBGYN Authors: Xiao-hong Lei, Xiao Wang, Shu-yi Shao, Ke-qin Hua, Ying Zhang Tags: Full length article Source Type: research

To drain or not to drain: A propensity score analysis of abdominal drainage after colorectal surgery for endometriosis
Bowel endometriosis is one of the most severe forms of deep endometriosis (DE) affecting 5  % to 12 % of patients with endometriosis [1]. The colorectum is involved in up to 85 % of patients with bowel endometriosis [2]. Surgery is an option for women experiencing pain and/or infertility after failure of medical treatment or when an organ function is compromised, such as hydronephro sis or digestive stenosis [3]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 22, 2024 Category: OBGYN Authors: Adrien Crestani, Eric de Labrouhe, Marjolaine Le Gac, Kamila Kolanska, Cl ément Ferrier, Cyril Touboul, Yohann Dabi, Emile Darai Tags: Full length article Source Type: research

Exome sequencing in genuine empty follicle syndrome: Novel candidate genes
Empty follicle syndrome (EFS) is a female fertility disorder characterized by the complete failure to retrieve oocytes despite apparently normal ovarian follicular development and successful ovarian puncture [1]. Its prevalence ranges from 0.045  % to 7 % [2]. False EFS (fEFS) occurs due to inadequate levels of circulating HCG or LH, often indicating errors in pharmaceutical preparation, administration, physician procedures during oocyte retrieval, or patient-related factors [3]. In contrast, genuine EFS (gEFS) occurs despite a correctl y administered ovulation trigger. (Source: European Journal of Obstetrics, Gynecolo...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 22, 2024 Category: OBGYN Authors: Belen Lled ó, Juan J. Piqueras, Francisca M. Lozano, Mónica Hortal, Ruth Morales, José A. Ortiz, Jaime Guerrero, Andrea Benabeu, Rafael Bernabeu Tags: Full length article Source Type: research

European Urogynaecological Association position Statement: The role of urodynamics in stress urinary incontinence evaluation and treatment decision
Stress urinary incontinence (SUI) is defined as a condition characterized by the involuntary leakage of urine during activities that increase intra-abdominal pressure, such as coughing, sneezing, laughing, or exercising [1,2], that typically occurs due to weakened or damaged pelvic floor muscles and/or the sphincter mechanism that controls urine flow [2]. It is a common health condition, affecting 5  % up to 35 % of the general female population [1], which may decrease quality of life [3] with a significant economic impact on health systems, necessitating the implementation of cost-effective management plans [4]. (Sour...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 21, 2024 Category: OBGYN Authors: Alessandro Ferdinando Ruffolo, Sofia Tsiapakidou, Yair Daykan, Stefano Salvatore, Stavros Athanasiou, Andrea Braga, Michele Meschia, Christian Phillips, Maurizio Serati Tags: Review article Source Type: research

Construction of deep learning-based convolutional neural network model for automatic detection of fluid Hysteroscopic endometrial micropolyps in infertile women with chronic endometritis
Deep learning is one of the artificial intelligence models that are actively introduced into clinical practice to assist healthcare providers due to its well-fitting to medical image analysis [1]. One of the most advanced algorithms among the deep learning models is convolutional neural network (CNN). A CNN model comprises a circuit of artificial neurons/nodes that exceed in object recognition and has been developed to the performance of the expert level [2]. The value of the CNN models is that their outputs can provide the probability of the disease, contrary to physicians being able to give only two judgments (presence o...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 21, 2024 Category: OBGYN Authors: Kotaro Kitaya, Tadahiro Yasuo, Takeshi Yamaguchi, Yuko Morita, Atsumi Hamazaki, Shinji Murayama, Takako Mihara, Masaya Mihara Tags: Full length article Source Type: research

Changes in metabolic acidosis following birth in intensive care unit neonates
Acidosis in the fetus-neonate is often measured at the time of delivery from samples of arterial and venous umbilical cord blood. The cord blood arterial pH and base excess (BE) in particular, reflecting the degree of metabolic acidosis present in the fetus just prior to birth, may be used retrospectively to assess the impact of intrapartum events, timeliness of interventions, and prospectively to guide newborn treatment (e.g., therapeutic hypothermia) [1 –3]. Severe acidosis (pH ≤ 7.1 and especially ≤ 7.0) in the umbilical cord artery is commonly used to assess the risk of fetal neurologic injury attributabl...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 20, 2024 Category: OBGYN Authors: Natalie T Simon, Patricia M Hagan, Karilynn M Rockhill, Kent D Heyborne Tags: Full length article Source Type: research

How does maternal anemia affect the levels of umb ılıcal cord braın-derıved neurotrophıc factor?
Iron deficiency anemia affects billions of people worldwide, and without anemia, iron deficiency is even the most common nutritional deficiency [1,2] Anemia is a global health problem which children and pregnant women throughout the world. World Health Organization estimates that 42% of children who are younger than 5 years of age and 40% of pregnant women have anemia [1]. Enlargement of the maternal red blood cell mass during pregnancy and the Growing placenta and the fetus triples the amount of iron needed [2]. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 18, 2024 Category: OBGYN Authors: G ökçe İpek Aytok, Asuman Akkaya Fırat, İlke Mungan Akın, Ayşegül Özel Tags: Full length article Source Type: research

Evaluation of serum CA125, HE4 and CA724 and the risk of ovarian malignancy algorithm score in the diagnosis of high-grade serous ovarian cancer
Over the last 20  years, there has been a continuous increase in the number of cases of ovarian cancer, which is the most lethal gynaecological cancer. In 2020, there were approximately 300,000 new cases and 200,000 deaths worldwide due to ovarian cancer [1]. High-grade serous ovarian cancer (HGSOC) is the most co mmon and aggressive form, and is often found as distant metastasis at the time of initial diagnosis due to the lack of specific symptoms [2]. Compared with other histological types, HGSOC exhibits a higher tendency to recur and develop resistance to chemotherapy within 2 years of diagnosis [3]. (Source: Europ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 18, 2024 Category: OBGYN Authors: Deyu Hu, Jun Qian, Fenghua Yin, Bing Wei, Jiayu Wang, Huijuan Zhang, Haiou Yang Tags: Full length article Source Type: research

Meta-analysis of the efficacy of neoadjuvant chemotherapy for locally advanced cervical cancer
Cervical cancer is one of the most common gynaecological malignancies, and although the level of screening and early prevention of cervical cancer has improved considerably in recent years, cervical cancer remains an important malignancy threatening women's health [1]. The current incidence of cervical cancer in China poses a serious challenge [2]. Traditional surgery is controversial for patients with cervical cancer of stage IIb and above [3]. However, neither improvements in surgical techniques and methods nor advances in radiotherapy equipment and techniques have significantly improved cervical cancer survival rates fo...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 18, 2024 Category: OBGYN Authors: Daying Wang, Xiuli Fang Tags: Review article Source Type: research

Should we should consider day 3 blastomere number during single vitrified-warmed blastocyst transfer cycle? A retrospective study
The success of frozen-warmed transfer cycles has improved markedly with the emergence of vitrification (VIT). Reportedly, vitrified-warmed embryos/blastocysts transfer cycles achieve equivalent or higher clinical outcomes than fresh embryos/blastocysts transfer cycles [1,2]. Furthermore, assisted reproductive technology (ART) centers worldwide utilizes single vitrified-warmed blastocyst transfer to obtain a single healthy baby. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 17, 2024 Category: OBGYN Authors: Haisu Zhou, Lianmin Ye, Huan Zhang, Yi Zheng, Wumin Jin Tags: Full length article Source Type: research

Saliva-based microRNA diagnostic signature for the superficial peritoneal endometriosis phenotype
Patients with superficial peritoneal endometriosis (SPE) present with symptoms suggestive of endometriosis but clinical and imaging exams are inconclusive. Consequently, laparoscopy is usually necessary to confirm diagnosis. The present study aimed to evaluate the accuracy of microRNAs (miRNAs) to diagnose patients with SPE from the ENDOmiARN cohort (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 17, 2024 Category: OBGYN Authors: Sofiane Bendifallah, Yohann Dabi, St éphane Suisse, Johanna Ilic, Léa Delbos, Mathieu Poilblanc, Philippe Descamps, Francois Golfier, Ludmila Jornea, Delphine Bouteiller, Cyril Touboul, Anne Puchar, Emile Daraï Tags: Full length article Source Type: research

Inside Back Cover - Editors with images
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 16, 2024 Category: OBGYN Source Type: research

Prenatal diagnosis and outcomes for fetuses with suspected pelvic kidney
Pelvic kidney is a form of renal ectopia, occurring with a frequency of 1 in 900 live births [1]. The pelvic kidneys are located in the presacral region, below the aortic bifurcation. Pelvic region localization is due to a lack of elevation of the kidneys in the early embryonic period [2]. The pelvic kidneys were malrotated and their hiluses were displaced anteriorly. Ultrasonographic diagnosis of the pelvic kidney is difficult due to the shadow of the pelvic iliac crests and intestines. The anterior position of the hilum, horizontal placement of the kidney, and smaller size of the kidney make diagnosis more difficult. (So...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 15, 2024 Category: OBGYN Authors: Refaettin Sahin, Atakan Tanacan, Hakki Serbetci, Osman Onur Ozkavak, Murat Haksever, Alperen Simsek, Ozgur Kara, Dilek Sahin Tags: Full length article Source Type: research

Perinatal Science International: a new meeting of the European Association of Perinatal Medicine
Over March 7-9th 2024, a group of around 42 academics, clinicians, basic scientists, and policymakers with an interest in perinatal medicine came together on the historic island of San Servolo in the Venetian lagoon, for the first meeting of Perinatal Science International. Here we describe the genesis of Perinatal Science International, the rationale for its establishment, insights that emerged at the initial meeting, and our ambitions for future editions. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 15, 2024 Category: OBGYN Authors: Neena Modi, Bo Jacobsson, Diogo Ayres de Campos, K. Beardsall, J.P. Boardman, Y.S. Chong, V. Cornelius, G. Ekman-Ordeberg, L. Fabbri, S. Kumar, T. Lavin, C. Lees, R. Luengo-Fernandez, R. Menon, V. Niklas, E. Schleussner, O. Simetka, W. Tarnow-Mordi, M. Tu Tags: Short communication Source Type: research

Vaginal foreign body in the pediatric patient: A systematic review
Vaginal foreign objects represent a clinical and diagnostical challenge in pediatric gynecology, necessitating a thorough understanding of their clinical presentation and optimal management. Several case reports, case series and retrospective studies have been published, highlighting rare or complex cases. A recent narrative review that included patients with a self-inserted object up to the age of 20, presented an overview of 40 recent cases [1]. However, a comprehensive systematic review of literature is lacking. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - April 15, 2024 Category: OBGYN Authors: E. Umans, M. Boogaerts, B. Vergauwe, A. Verest, S. Van Calenbergh Tags: Review article Source Type: research