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European Journal of Obstetrics, Gynecology, and Reproductive BiologyEuropean Journal of Obstetrics, Gynecology, and Reproductive Biology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. subscribe with MyMedWormSubscribe to this data using MyMedWorm.subscribe with GoogleReaderSubscribe to this data using GoogleReader.subscribe with BloglinesSubscribe to this data using Bloglines.subscribe with MyYahooSubscribe to this data using MyYahoo.

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Announcementsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - November 14, 2009 Category: OBGYN Source Type: journals

Editors’ highlightsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The aim of this Journal is to publish review articles regularly every month and we are happy to continue to do so in the last issue of 2009. The first article deals with the role of myo-inositol in human reproduction and the second is a systematic review of the accuracy of C-reactive protein determination in predicting chorioamnionitis. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - October 23, 2009 Category: OBGYN Authors: W. Künzel, J. Drife Tags: The Editors' Section Source Type: journals

Announcementsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - October 16, 2009 Category: OBGYN Source Type: journals

Editorial Boardemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - October 16, 2009 Category: OBGYN Source Type: journals

Working conditions survey and trainees situation: New approach to auditing the situation of European trainees in obstetrics and gynaecology ten years lateremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Steps towards harmonisation are being made. Hospital visitation systems should be further introduced. Not all countries have remunerated training posts. Assessment should become more homogeneous. Compliance with the European Working Time Directive (EWTD) is a big challenge. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - October 5, 2009 Category: OBGYN Authors: David Rodríguez, Panagiotis Christopoulos, Nuno Martins, Pille Pärgmäe, Henrica M.J. Werner Tags: European View Source Type: journals

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(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 30, 2009 Category: OBGYN Source Type: journals

Accuracy of C-reactive protein determination in predicting chorioamnionitis and neonatal infection in pregnant women with premature rupture of membranes: A systematic reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Preterm premature rupture of the fetal membranes (PPROM) is associated with intra-uterine infection. Early detection of intra-uterine infection may help prevent neonatal sepsis. C-reactive protein (CRP) is an acute phase protein often elevated when inflammation is present. The aim of this review was to assess whether CRP accurately predicts chorioamnionitis and/or neonatal sepsis in women with PPROM.We searched Medline and Embase databases for articles reporting on CRP and chorioamnionitis and/or neonatal sepsis. Two reviewers extracted clinical and methodological study characteristics and test accuracy data. Acc...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 30, 2009 Category: OBGYN Authors: Rafli van de Laar, David P. van der Ham, S. Guid Oei, Christine Willekes, Carl P. Weiner, Ben W.J. Mol Tags: Reviews Source Type: journals

Effects of menopausal hormone therapy on hemostatic parameters, blood pressure, and body weight: Open-label comparison of randomized treatment with estradiol plus drospirenone versus estradiol plus norethisterone acetateemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objectives: Clinical studies have reported changes in hemostatic parameters in women taking menopausal hormone therapy (HT) and a small increased risk of venous thromboembolism. We compared the effects of two different HTs on hemostatic parameters in postmenopausal women.Study design: An open-label, randomized study conducted at two centers in Germany compared continuous 28-week combined HT with 17β-estradiol 1mg plus drospirenone 2mg (E2/DRSP) daily versus E2 1mg plus norethisterone acetate 0.5mg (E2/NETA) daily in healthy postmenopausal women. Changes in D-dimer levels from baseline to the end of treatment, as...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 25, 2009 Category: OBGYN Authors: Wolfgang Junge, Volker El-Samalouti, Christoph Gerlinger, Matthias Schaefers Tags: Reproductive Medicine and Endocrinology Source Type: journals

Contribution of myo-inositol to reproductionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article will review the involvement of inositol in female reproduction. After describing the biologic function of inositol and its derivatives, studies are quoted in which the role of inositol in fertility, oogenesis, and polycystic ovary syndrome are examined. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 24, 2009 Category: OBGYN Authors: E. Papaleo, V. Unfer, J.P. Baillargeon, T.T. Chiu Tags: Reviews Source Type: journals

Robot assisted laparoscopic transperitoneal para-aortic lymphadenectomy in the management of advanced cervical carcinomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Robot assisted transperitoneal laparoscopic para-aortic lymphadenectomy is feasible and provides the surgeon with greater precision than classical laparoscopy. Larger prospective multicentric trials are needed to validate the generalised usefulness of this technique. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 23, 2009 Category: OBGYN Authors: Maxime Fastrez, Jean Vandromme, Pascale George, Serge Rozenberg, Michel Degueldre Tags: Gynaecology and Gynaecological Oncology Source Type: journals

A longitudinal 2-year follow-up of quality of life in women referred for colposcopy after an abnormal cervical smearemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Women experienced long-lasting negative effects on their mental health, but not on their physical health after referral for colposcopy. LLETZ had no measurable influence on QoL at any of the visits. This indicates that it is not the severity of the lesions or the treatment itself that affects women but the fact of having had an abnormal cervical smear identified. Depressive mood may be a major variable for the perception of low QoL. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 23, 2009 Category: OBGYN Authors: C. Hellsten, K. Sjöström, P.G. Lindqvist Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Methylation of the long control region of HPV16 is related to the severity of cervical neoplasiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objective: Oncogenic human papillomavirus (HPV) is the cause of cervical cancer. Hypermethylation of the CpG islands located at the long control region (LCR) of the HPV genome may regulate the expression of the major oncogenes E6 and E7, and may relate to cancer progression. The goal of the present study was to investigate the methylation patterns of CpG dinucleotides contained within the LCR of the HPV16 genome in a collection of clinical specimens comprising the full spectrum of cervical carcinogenesis.Study design: The status of LCR methylation was investigated in HPV16-infected cervical precancer and cancer c...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 23, 2009 Category: OBGYN Authors: Dah-Ching Ding, Ming-Hsien Chiang, Hung-Cheng Lai, Chao Agnes Hsiung, Chang-Yao Hsieh, Tang-Yuan Chu Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Effects of strontium ranelate, raloxifene and misoprostol on bone mineral density in ovariectomized ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Strontium ranelate, raloxifene and misoprostol can prevent bone loss in the vertebrae, whereas strontium ranelate can also prevent bone loss in the femur of ovariectomized rats. Strontium ranelate increases greater than raloxifene and misoprostol BMD in the vertebrae.Condensation: Strontium ranelate may increase both vertebral and femur BMD in ovariectomized rats while raloxifene and misoprostol may only increase lumbar spine BMD. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 23, 2009 Category: OBGYN Authors: Nefise Ahmet-Camcioglu, Tulay Okman-Kilic, Gulay Durmus-Altun, Galip Ekuklu, Mustafa Kucuk Tags: Reproductive Medicine and Endocrinology Source Type: journals

Editors’ highlightsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
With summer gone and Christmas still to come, November is a month of long dark nights in Europe. These are good for academic work and discussion, and in some countries this is a busy time for local and regional meetings. In London the Academic Association of Obstetrics and Gynaecology (AAOG) is about to hold its fourth annual meeting. It evolved from an older organisation, the Association of Professors of Obstetrics and Gynaecology, with the purpose of being a voice for academics in our specialty in the British Isles. The AAOG works closely with the Royal College of Obstetricians and Gynaecologists, and as well as developi...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 22, 2009 Category: OBGYN Authors: J. Drife, W. Künzel Tags: The Editors' Section Source Type: journals

Management of asymptomatic mid-trimester lower segment scar dehiscenceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We discuss an interesting case where asymptomatic uterine scar dehiscence presented in the early second trimester. Uterine scar dehiscence during pregnancy, defined as asymptomatic thinning or separation of a prior uterine scar, is found incidentally in (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 4, 2009 Category: OBGYN Authors: Srilatha Gorthi, Nigel A.B. Simpson, Virginia Lodge, Richard J.C. Dunham, Geoffrey Lane Tags: Letters to the Editor - Brief Communications Source Type: journals

Risk factors for reproductive tract infections among married women in rural areas of Anhui Province, Chinaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Among married women in rural China, the prevalence of RTIs was high, indicating the need for health education. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 4, 2009 Category: OBGYN Authors: Xiu-Jun Zhang, Qiong Shen, Guo-Ying Wang, Yu-Ling Yu, Ye-Huan Sun, Guo-Bin Yu, Dong Zhao, Dong-Qing Ye Tags: Reproductive Medicine and Endocrinology Source Type: journals

Factors influencing delivery mode for nulliparous women with a singleton pregnancy and cephalic presentation during a 17-year periodemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: These data demonstrate that the increasing trend of unplanned abdominal delivery in nulliparous women with a singleton pregnancy and cephalic presentation may be partially explained by advancing maternal age, and other obstetric factors also play a significant role. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 4, 2009 Category: OBGYN Authors: Vimla Sharma, Gabrielle Colleran, Brendan Dineen, Marie B. Hession, Gloria Avalos, John J. Morrison Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

Hysteroscopic evaluation of endocervical and endometrial lesions observed after different procedures of embryo transfer: A prospective comparative studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objective: Endocervical and endometrial damage observed after different procedures of embryo transfer (ET) were investigated using diagnostic hysteroscopy.Study design: Prospective, descriptive and comparative study, in an Infertility centre, University Hospital. Hundred consecutive infertile patients with a normal uterine cavity, included in an IVF program, were enrolled between May 1st, 2006 and April 30th, 2007. All the patients had a diagnostic hysteroscopy immediately after trial ET using soft ET catheters: (i) IVF Sydney Set (Cook, Limerick, Ireland) (n=27), (ii) Elliocath (Ellios, Paris, France) (n=34), (i...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 3, 2009 Category: OBGYN Authors: Christophe Poncelet, Christophe Sifer, Delphine Hequet, Raphael Porcher, Jean-Philippe Wolf, Michèle Uzan, Guillaume Ducarme Tags: Reproductive Medicine and Endocrinology Source Type: journals

Evaluation of the tocolytic effect of morphine in a mouse model of lipopolysaccharide-induced preterm delivery: The role of nitric oxideemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Morphine increases the gestational duration and decreases the preterm delivery rate induced by LPS probably through modulation in NO release. l-NAME, unlike naltrexone, reversed the effect of morphine on preterm delivery, demonstrating the involvement of nitric oxidergic pathway. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 3, 2009 Category: OBGYN Authors: Mehrak Javadi-Paydar, Ali Lesani, Ramin Vakilipour, Payam Ghazi, Seyed Mohammad Tavangar, Sedigheh Hantoushzadeh, Abbas Norouzi, Ahmad Reza Dehpour Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

Severe dysuria attributable to a solitary leiomyoma of the greater omentumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We found an unusual case of solitary leiomyoma originating from the greater omentum presenting as severe dysuria. A 35-year-old woman visited our outpatient clinic complaining of severe dysuria for the previous 10 days. The pain began before the initiation of voiding and continued during micturition. She had no history of medical or surgical treatment. Routine urine analysis revealed no abnormality. A rectovaginal examination revealed a firm mass, the size of a man's fist, in her mid-lower abdomen and there was mild tenderness on palpation. Transrectal ultrasonography (US) revealed a solitary 8.5cm×6.0cm sized isoechoic s...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Sung-Bum Cho, Sa Ra Lee, Min-Hyung Jung, Woong Ju, Seung Cheol Kim Tags: Letters to the Editor - Brief Communications Source Type: journals

False-positive immunometric assay results in the detection of phantom human chorionic gonadotropin: A situation with possible severe iatrogenic consequencesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We found a situation that in our opinion is insufficiently recognized by clinicians and biochemists, despite several publications reporting the limitations of immunometric assays for human chorionic gonadotropin (hCG) and the hCG reference service directed by Dr Cole in New-Mexico underlining the risk of needless therapy for false diagnosis of trophoblastic disease . (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: J. Seror, N. Chabbert-Buffet, F. Millot, N. Lahlou, S. Uzan, N. Berkane Tags: Letters to the Editor - Brief Communications Source Type: journals

Pregnancy after hysteroscopic tubal sterilization despite two hysterosalpingograms showing bilateral occlusionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report a case of spontaneous pregnancy after hysteroscopic tubal sterilization with failed procedure on the right side but confirmation of bilateral tubal occlusion by two hysterosalpingograms (HSG) and chromolaparoscopy. The question underlined by this case is how to check the bilateral tubal occlusion. ESSURE® system (Conceptus Inc., Mountain View, CA) involves the placement of a micro-insert in the proximal section of fallopian tube under hysteroscopic approach using a specialized delivery device. Contraception is necessary for 3 months after the procedure. According to the French recommendation, an abdominal X-ray ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Stéphane Ploteau, Patrice Lopes Tags: Letters to the Editor - Brief Communications Source Type: journals

Urinary ascites following caesarean section: An unusual presentation of bladder injuryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 39-year-old woman underwent an elective caesarean section (CS) following an emergency CS in her first pregnancy. Next morning, the urinary catheter was removed and she subsequently reported some abdominal pain. It became worse and she did not pass urine for 12h. The abdomen was distended, with audible bowel sounds. She was commenced on intravenous fluids and when the urinary catheter was replaced 2000ml of urine were drained. Soon she felt more comfortable and her abdomen became less distended. An ultrasound scan showed a small amount of ascites in the right flank with no free fluid in the pelvis. (Source: European Journ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Ismail Hassan, Carolina López, Harry Gee, Philip Toozs-Hobson Tags: Letters to the Editor - Brief Communications Source Type: journals

Impact of HTLV-I in quality of life and urogynecologic parameters of women with urinary incontinenceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Poor quality of life and physical abnormalities were identified in incontinent HTLV-I seropositive women when compared with incontinent HTLV-I seronegative women. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Monica Suzana Costa Diniz, Paulo Cezar Feldner, Rodrigo Aquino Castro, Marair Gracio Ferreira Sartori, Manoel João Batista Castello Girão Tags: Gynaecological Urology Source Type: journals

Vulvar and vaginal cancers and dysplasia in France—An analysis of the hospital medical information system (PMSI) databaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The burden of hospitalizations due to vulvar and vaginal cancers is substantial. Further research is needed to assess the outpatient burden due to these diseases especially for precancerous dysplasia which may be mostly managed in an outpatient setting. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Vanessa Rémy, Patrice Mathevet, Alexandre Vainchtock Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Evidence of measles virus antigens and RNA in endometrial canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: We demonstrate for the first time a link between endometrial cancer and the presence of viral antigens and RNA of the measles virus, although these findings do not necessarily signify a causal relationship between the cancer and the virus. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Daniel Benharroch, Irina Klinkovich, Benjamin Piura, Ruthy Shaco-Levy, Jacob Gopas Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Performance and cost analysis of Siriraj liquid-based cytology: A direct-to-vial studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objective: To compare the cytological diagnoses, specimen adequacy, and cost of the Siriraj liquid-based cytology (LBC) with those of the conventional smear technique.Study design: An observational study with historical comparison was conducted in a tertiary university hospital. Cytological reports of 23,676 Siriraj-LBC specimens obtained in 2006 were compared with those of 25,510 conventional smears obtained in 2004.Results: Overall prevalence of abnormal cervical cytology detected by conventional smear was 1.76% and by Siriraj-LBC was 3.70%. Compared with the conventional method, the Siriraj-LBC yielded a signi...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Somsak Laiwejpithaya, Mongkol Benjapibal, Sujera Laiwejpithaya, Weerasak Wongtiraporn, Suthi Sangkarat, Manee Rattanachaiyanont Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Prediction of pelvic pathology in subfertile women with combined Chlamydia antibody and CA-125 testsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The combined test adds hardly anything to the predictive value of CAT alone to diagnose severe tubal disease. The combined test is better than the CAT to predict severe pelvic pathology, but is not significantly better than the CA-125. If both the CAT and CA-125 are normal one could consider not performing a laparoscopy. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Josien Penninx, Monique Brandes, Jan Peter de Bruin, Peter M. Schneeberger, Carl J.C.M. Hamilton Tags: Reproductive Medicine and Endocrinology Source Type: journals

Maternal pro-hepcidin at term correlates with cord blood pro-hepcidin at birthemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objective: Hepcidin, a small 25 amino-acid antimicrobial peptide, has a significant role in the regulation of iron homeostasis. Pro-hepcidin, an 84 amino-acid peptide, is a precursor of the active hepcidin. The main aim of this study was to examine the association of maternal serum pro-hepcidin with cord blood pro-hepcidin levels in term pregnancies, and whether maternal and newborn iron status measurements correlate with the pro-hepcidin level.Study design: The population consisted of 193 pregnant women admitted to the Kuopio University Hospital (Finland) for delivery, and their full-term newborn infants (cord b...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Mari Ervasti, Ulla Sankilampi, Susanna Luukkonen, Seppo Heinonen, Kari Punnonen Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

Contribution and limit of the model of perfused cotyledon to the study of placental transfer of drugs. Example of a protease inhibitor of HIV: Nelfinaviremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objectives: The perfused cotyledon model is a very useful method to study placental transfer of drugs. Here we studied placental transfer of the human immunodeficiency virus protease inhibitor nelfinavir using the non-recirculating dual human placental perfusion with a main goal to determining the clearance index of nelfinavir as related to maternal concentrations, and analyze the conditions under which ex vivo and in vivo data can be correlated.Study design: Thirteen human cotyledons, obtained after uneventful term pregnancies, were perfused in an open double circuit with nelfinavir (320–4436μg/l) and a freel...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Laurent Gavard, Delphine Beghin, François Forestier, Yvon Cayre, Gilles Peytavin, Laurent Mandelbrot, Robert Farinotti, Sophie Gil Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

Does young maternal age increase the risk of adverse obstetric, fetal and neonatal outcomes: A cohort studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: In our population, younger maternal age was significantly and consistently associated to greater risks of fetal death and anaemia and to lower risks of adverse obstetric outcomes. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Claire M. de Vienne, Christian Creveuil, Michel Dreyfus Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

An efficient protocol for the detection of chromosomal abnormalities in spontaneous miscarriages or foetal deathsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Adopting this sequential protocol, chromosomal complement information was available even in cases with culture failure. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Sofia Dória, Filipa Carvalho, Carla Ramalho, Vera Lima, Tânia Francisco, Ana Paula Machado, Otília Brandão, Mário Sousa, Alexandra Matias, Alberto Barros Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

Maternal infection rates after cesarean delivery by Pfannenstiel or Joel–Cohen incision: A multicenter surveillance studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The Joel–Cohen technique is faster than the Pfannenstiel technique but is associated with a higher incidence of endometritis. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - September 1, 2009 Category: OBGYN Authors: Anne Marie Dumas, Raphaële Girard, Louis Ayzac, Emmanuelle Caillat-Vallet, Françoise Tissot-Guerraz, Agnès Vincent-Bouletreau, Michel Berland Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

Editors’ highlightsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In previous issues we have had the pleasure of offering reviews about a wide variety of subjects and this month we are happy to continue with five reviews ranging from the methodology of systematic reviews to COX-2 expression in ovarian malignancies. On page 121, Knox and colleagues from Birmingham, UK, memorably describe systematic reviews of fetal medicine as “a tool for translation of research findings from a few expert centres to a wider health care specialty”. They identified 84 reviews which met their inclusion criteria – over half being in the field of fetal pathology. The authors say there is a paucity of goo...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 31, 2009 Category: OBGYN Authors: W. Künzel, J. Drife Tags: The Editors' Section Source Type: journals

An unusual case of vaginal blood lossemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Wegener's granulomatosis (WG) is a vasculitis characterized by necrotizing granulomatous inflammation of small and medium sized vessels of predominantly the upper and lower respiratory tract and the kidneys. Almost every organ systems can be affected, although involvement of the genital tract is rare . The pathogenesis is regarded as inflammatory noninfectious and 90% of patients present with antineutrophil cytoplasmatic antibodies (ANCA). Diagnosis is established by tissue biopsy showing signs of a necrotizing granulomatous vasculitis. Here we present a case of WG with initial presentation in the genital tract. (Source: E...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 17, 2009 Category: OBGYN Authors: Yvonne Hendrix, Mariëlle P. Wuite-Eversdijk, Jos W. Meijer, Arjan A. Kraayenbrink, Clemens Richter Tags: Letters to the Editor - Brief Communications Source Type: journals

Expression of the melatonin receptor and tryptophan hydroxylase in placentas of the fetus with intra-uterine stressemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We found that melatonin is the only hormone of the neuroendocrine system present in all systems, demonstrating synchronized biological rhythmic coordination and it is considered to be one of the most powerful natural antioxidants and is capable of controlling stress . Although the mechanisms regarding its control of fetal circadian rhythm have been described, how melatonin acts in fetal stress conditions has not been fully established . Moreover, some studies identify the presence of melatonin in the placenta , but no information regarding the mechanisms of synthesis, the production cells or alterations possibly associated...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 17, 2009 Category: OBGYN Authors: Rosana R.M. Corrêa, Sue E.G. Barrilari, Camila S.O. Guimarães, Renata C. Rossi e Silva, Janaínna G.P. Olegário, Camila L. Cavellani, Flávia A. Oliveira, Ana K.M. Salge, Vicente P.A. Teixeira, Eumênia C.C. Castro Tags: Letters to the Editor - Brief Communications Source Type: journals

Transabdominal uterine arteries Doppler at 12–14th and 20–24th week of gestation and pregnancy outcome: A prospective studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: This study indicates that early evaluation of arterial uterine RI and presence of notches may be predictive of low birth weight and intra uterine growth retardation in a high risk population. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 17, 2009 Category: OBGYN Authors: Stefania Rampello, Luigi Frigerio, Elena Ricci, Elena Rota, Marzia Lucianetti, Fabio Parazzini Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

Ectopic pregnancy after caesarean section sterilisationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 39-year-old woman presented to the acute gynaecology admission unit complaining of sudden onset constant left iliac fossa pain with dizziness. Her last menstrual period had been six weeks before and a pregnancy test was positive. There was no vaginal bleeding or shoulder tip pain. She had five children, four by spontaneous vaginal deliveries and one by caesarean section in 2003, when she had bilateral tubal ligation. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 16, 2009 Category: OBGYN Authors: Aisha Janjua, Joanne Beasley Tags: Letters to the Editor - Brief Communications Source Type: journals

Mechanical evaluation of synthetic biomaterials used in the correction of pelvic floor disorders—Experimental study in rabbitsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: In our abdominal rabbit model, as regards mechanical properties, heavyweight PET seems to be the optimal biomaterial. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 16, 2009 Category: OBGYN Authors: Fabrice Sergent, Nicolas Desilles, Yann Lacoume, Claude Bunel, Jean-Paul Marie, Loïc Marpeau Tags: Gynaecological Urology Source Type: journals

Histological response is not a prognostic factor after neoadjuvant chemotherapy in advanced-stage ovarian cancer with no residual diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: These results suggest that the degree of the histological response has a limited impact on survival when complete debulking surgery is achieved at IDS. The degree of tumour cell viability after initial chemotherapy is not a reliable marker for modifying chemotherapy after debulking surgery in such patients. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 16, 2009 Category: OBGYN Authors: Jean-Guillaume Ferron, Catherine Uzan, Annie Rey, Sebastien Gouy, Patricia Pautier, Catherine Lhommé, Pierre Duvillard, Philippe Morice Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Menstrual disorders and subfertility in Spanish hairdressersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Our results suggest an increased risk of subfertility and menstrual disorders in hairdressers compared to a control group of office workers and shop assistants. More research is needed in order to elucidate what particular occupational exposure may explain this association. Nevertheless, it would seem that chemicals present in hairdressing salons could be responsible. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 16, 2009 Category: OBGYN Authors: Elena Ronda, Ana Maria García, José Sánchez-Paya, Bente E. Moen Tags: Reproductive Medicine and Endocrinology Source Type: journals

Attitude towards cessation among French pregnant smokers: Explaining the poor uptake of specialised supportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Despite being offered professional help, many pregnant heavy smokers do not feel ready to stop smoking. Their attitude towards cessation illustrates ambivalence. There is thus a need for coordinated efforts between antenatal care providers and smoking treatment specialists in order to enhance pregnant smokers’ motivation to quit. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 16, 2009 Category: OBGYN Authors: Monique Y. Baha, Anne-Laurence Le Faou Tags: Obstetrics and Maternal-Fetal Medicine Source Type: journals

The European perinatal health report: Delivering comparable data for examining differences in maternal and infant healthemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: In December 2008, the first-ever European Perinatal Health Report was released by EURO-PERISTAT. Part of the EU Health Programme for health surveillance and reporting, this landmark report presents indicators of perinatal health and care derived from routine statistical data in 25 EU Member States and Norway. It also includes chapters from three other European projects with perinatal data: SCPE on cerebral palsy, EUROCAT on congenital anomalies and EURONEOSTAT on very preterm babies admitted to intensive care. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 16, 2009 Category: OBGYN Authors: Meagan Zimbeck, Ashna Mohangoo, Jennifer Zeitlin, the EURO-PERISTAT Report Writing Committee Tags: European View Source Type: journals

Announcementsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 14, 2009 Category: OBGYN Source Type: journals

Editorial Boardemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 14, 2009 Category: OBGYN Source Type: journals

Transverse myelitis: A rare cause of puerperal pyrexiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Common causes of puerperal pyrexia include puerperal sepsis, urinary tract infection, breast complications, thrombosis, and malaria. Infections and autoimmune disorders are outlined as triggering mechanisms but the exact etiology remains unknown. We came across an interesting case of puerperal pyrexia caused by transverse myelitis, an inflammatory disorder involving the spinal cord. There is no case report of transverse myelitis in the puerperium, though a few cases have been reported during pregnancy . (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 12, 2009 Category: OBGYN Authors: Savita Rani Singhal, Smiti Nanda Tags: Letters to the Editor - Brief Communications Source Type: journals

Assessment of preoperative serum prolidase activity in epithelial ovarian canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objective: Prolidase is a cytosolic exopeptidase that cleaves iminodipeptides with C-terminal proline and hydroxyproline and plays a major role in collagen turnover. The aim of this study was to evaluate preoperative serum prolidase activity, total oxidant status (TOS), and total antioxidant capacity (TAC) in patients with newly diagnosed epithelial ovarian cancer (EOC).Study design: Serum prolidase activity, TOS, and TAC were measured spectrophotometrically in both EOC cases (n=28) and controls (n=28).Results: Preoperative serum prolidase activity and TOS were significantly higher in patients with EOC compared t...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 11, 2009 Category: OBGYN Authors: Hakan Camuzcuoglu, Dagistan Tolga Arioz, Harun Toy, Sefa Kurt, Hakim Celik, Nurten Aksoy Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Efficacy of using electrosurgical bipolar vessel sealing during vaginal hysterectomy in patients with different degrees of operative difficulty: A randomised controlled trialemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Objective: To assess the efficacy of electrosurgical bipolar vessel sealing using the LigaSure® system during vaginal hysterectomy in comparison with conventional suture ligation method.Study design: 103 patients undergoing vaginal hysterectomy for benign conditions were randomised to either LigaSure® or Suture groups. Each group was divided into two subgroups according to the degree of surgical difficulty.Results: Participants in the LigaSure® had shorter procedure time (52.5min vs. 90min; p (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 11, 2009 Category: OBGYN Authors: Mounir Elhao, Khaled Abdallah, Ihab Serag, Mohamed El-Laithy, Wael Agur Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Analysis of outcome in women with borderline glandular change on cervical cytologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Colposcopic examination and biopsy of colposcopically identified abnormalities is reliable, with negative colposcopy having a high negative predictive value. We also recommend thorough colposcopic examination before any invasive investigation as over treatment may impact on the future reproductive outcome . (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 11, 2009 Category: OBGYN Authors: Bismeen A. Jadoon, Sean Kehoe, Kathleen Romain, Colin Clelland, Sudha S. Sundar Tags: Gynaecology and Gynaecological Oncology Source Type: journals

Age-specific differences in the treatment of cervical cancer in the east and the south of The Netherlands 1989–2004email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study aims to describe trends and variation in treatment and survival of cervical cancer in two regions in The Netherlands and to relate this to adherence to the treatment recommendations.Study design: Patient characteristics, tumour characteristics, treatment and follow-up data were collected for 1954 cervical cancer cases diagnosed in the period 1989–2004.Results: In FIGO stages IB-IIA 93% of patients were treated according to the recommendations of The Netherlands Working Group Gynaecologic Oncology. Older patients received radiotherapy more often than younger patients: 48% (95%CI 40–57) of patients older than ...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - August 11, 2009 Category: OBGYN Authors: Maaike A. van der Aa, Sabine Siesling, Lonneke V. v.d. Poll-Franse, Eltjo M. Schutter, Marnix L. Lybeert, Jan Willem W. Coebergh Tags: Gynaecology and Gynaecological Oncology Source Type: journals