Effects of equibiaxial mechanical stretch on extracellular matrix ‐related gene expression in human calvarial osteoblasts
Mechanical stretch commonly promotes craniofacial suture remodeling during interceptive orthodontics. The mechanical responses of osteoblasts in craniofacial sutures play a role in suture remodeling. Moreover, the extracellular matrix (ECM) produced by osteoblasts is crucial for the transduction of mechanical signals that promote cell differentiation. Therefore, we aimed to investigate the effect of mechanical stretch on cell viability and ECM ‐related gene‐expression changes in human osteoblasts. Human calvarial osteoblasts (HCObs) were subjected to 2% deformation. Caspase activity, MTT, and cell viability assays were...
Source: European Journal of Oral Sciences - November 26, 2018 Category: Dentistry Authors: Jiawei Zhang,
Shuhao Xu,
Yanggen Zhang,
Shujuan Zou,
Xiaobing Li Tags: Original Article Source Type: research
Proteomic analysis of dentin –enamel junction and adjacent protein‐containing enamel matrix layer of healthy human molar teeth
This study identified 46 proteins in DEJ and EOM. The protei ns identified have a variety of functions, including calcium ion‐binding, formation of extracellular matrix, formation of cytoskeleton, cytoskeletal protein binding, cell adhesion, and transport. Collagens were identified as the most dominant proteins. Tissue‐specific proteins, such as ameloblas tin and amelogenin, were also detected. Our findings reveal new insight into proteomics of DEJ and EOM, highly mineralized tissues that are obviously difficult to analyze. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 22, 2018 Category: Dentistry Authors: Michal J ágr,
Peter Ergang,
Statis Pataridis,
Marta Kolrosová,
Martin Bartoš,
Ivan Mikšík Tags: Original Article Source Type: research
Effect of margin design on fracture load of zirconia crowns
Zirconia ‐based restorations are showing an increase as the clinicians’ preferred choice at posterior sites because of the strength and esthetic properties of such restorations. However, all‐ceramic restorations fracture at higher rates than do metal‐based restorations. Margin design is one of severa l factors that can affect the fracture strength of all‐ceramic restorations. The aim of this study was to assess the effect of preparation and crown margin design on fracture resistance. Four groups of bilayer zirconia crowns (with 10 crowns in each group) were produced by hard‐ or soft‐machin ing technique, with...
Source: European Journal of Oral Sciences - November 22, 2018 Category: Dentistry Authors: Anneli Skjold,
Christian Schriwer,
Marit Øilo Tags: Original Article Source Type: research
Interaction between interferon regulatory factor 6 and glycine receptor beta shows a protective effect on developing nonsyndromic cleft lip with or without cleft palate in the Han Chinese population
Single ‐nucleotide polymorphisms (SNPs) in protein‐coding regions of genes which were previously reported to be associated with nonsyndromic cleft lip, with or without palate involvement (NSCL/P), were investigated. Twelve candidate loci [platelet‐derived growth factor C (PDGFC), platelet ‐derived growth factor subunit A (PDGFA), platelet ‐derived growth factor receptor alpha (PDGFRA), glycine receptor alpha 2 (GLRA2), glycine receptor beta (GLRB), ATP binding cassette subfamily A member 4 (ABCA4), MAF bZIP transcription factor B (MAFB), interferon regulatory factor 6 (IRF6), CCDC26 long non ‐coding RNA (CCDC26...
Source: European Journal of Oral Sciences - November 21, 2018 Category: Dentistry Authors: Di Wu,
Mei Wang,
Xingang Wang,
Yong ‐Biao Zhang,
Tao Song,
Ningbei Yin,
Zhenmin Zhao Tags: Original Article Source Type: research
Effect of glycerol on reconstructed human oral mucosa
This study aimed to investigate dose ‐dependent effects of glycerol on homeostasis and tissue integrity of in vitro‐reconstructed normal human buccal mucosa (RNHBM). Primary keratinocytes and fibroblasts were isolated and expanded from biopsies of mucosa from eight healthy volunteers. Ninety‐six samples of RNHBM were prepared an d exposed for 24 h to 17%, 42.5%, or 85% glycerol, or to distilled H2O (control). Sections were stained with haematoxylin and eosin (H&E) to evaluate epithelial thickness or used for immunohistochemistry to measure expression of Ki67 (proliferation), cleaved caspase ‐3 (apoptosis), and E...
Source: European Journal of Oral Sciences - November 19, 2018 Category: Dentistry Authors: Siri F. Kvalheim,
Victoria Xenaki,
Arild Kvalheim,
Stein ‐Atle Lie,
Mihaela C. Marthinussen,
Gunhild V. Strand,
Daniela E. Costea Tags: Original Article Source Type: research
Dental anxiety in relation to torture experiences and symptoms of post ‐traumatic stress disorder
Torture victims often show symptoms of dental anxiety when receiving dental care, but little systematic research is available. The purpose of this study was to explore torture experiences, symptoms of post ‐traumatic stress disorder (PTSD), and dental anxiety in refugees in Norway and to test the hypothesis that refugees with torture experiences are more prone to dental anxiety than refugees with no such experiences. A total of 173 refugees were interviewed shortly after an oral examination. The Mod ified Dental Anxiety Scale (MDAS) and the Harvard Trauma Questionnaire‐PTSS16 were administered verbally through attendin...
Source: European Journal of Oral Sciences - November 16, 2018 Category: Dentistry Authors: Ann C. H øyvik,
Birgit Lie,
Tiril Willumsen Tags: Original Article Source Type: research
‘One tooth one child’: evaluating the effects of diet and fertility on the oral health of women from archaeological sites in South America
Women from ancient societies have shown a higher prevalence of dental caries in comparison with men. Recent research has shown that the relationship between increased oestrogen production during pregnancy and decreased salivary flow is a possible cause for the higher levels of caries in women, which is in contrast to the traditional view of sexual division of labour resulting in unequal access to cariogenic food. In order to test these two hypotheses, individuals exhumed from 12 South American archaeological sites were examined for markers of oral health (caries, ante mortem tooth loss, deep caries, and enamel hypoplasia) ...
Source: European Journal of Oral Sciences - November 16, 2018 Category: Dentistry Authors: Maria Rita G. Carvalho,
Luis Pezo ‐Lanfranco,
Sabine Eggers Tags: Original Article Source Type: research
Progressive muscle relaxation therapy to relieve dental anxiety: a randomized controlled trial
Dental anxiety causes patients to refuse or delay treatment, which may exacerbate oral diseases. The aim of the current randomized controlled trial was to determine whether progressive muscle relaxation therapy could relieve dental anxiety. The trial included 68 periodontal patients with dental anxiety scores of ≥13 who were randomly assigned to either an intervention group or a control group (n = 34 per group). The intervention group was administered progressive muscle relaxation therapy for 20 min and oral health education for 15 min before periodontal treatment once per week for 4 wk. The control group was prov...
Source: European Journal of Oral Sciences - November 14, 2018 Category: Dentistry Authors: Eun S. Park,
Hyeon W. Yim,
Kang S. Lee Tags: Original Article Source Type: research
Corrigendum
European Journal of Oral Sciences, Volume 126, Issue 6, Page 533-533, December 2018. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 12, 2018 Category: Dentistry Tags: Corrigendum Source Type: research
Volume content for 2018
European Journal of Oral Sciences, Volume 126, Issue 6, Page 535-541, December 2018. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 12, 2018 Category: Dentistry Tags: Volume content for 2018 Source Type: research
Issue Information
European Journal of Oral Sciences, Volume 126, Issue 6, Page i-iii, December 2018. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 12, 2018 Category: Dentistry Tags: Issue Information Source Type: research
Reviewers 2018
European Journal of Oral Sciences, Volume 126, Issue 6, Page 534-534, December 2018. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 12, 2018 Category: Dentistry Tags: Reviewers 2018 Source Type: research
Author Guidelines
European Journal of Oral Sciences, Volume 126, Issue 6, Page 542-542, December 2018. (Source: European Journal of Oral Sciences)
Source: European Journal of Oral Sciences - November 12, 2018 Category: Dentistry Tags: Instructions to contributors Source Type: research
Inhibition of dentin matrix ‐bound cysteine cathepsins by potassium fluoride
This study investigated the use of potassium fluoride (KF) as a potential inhibitor of MMPs and CCs in dentin. Demineralized dentin beams were divided into groups (n = 10 in each group) and incubated in artificial saliva (AS, control), either alone or with one of seven concentrations of KF (6–238 mM fluoride) for 1, 7, and 21 d. After 21 d, all groups were further aged in AS for 6 months. Total MMP activity was screened using the colorimetric MMP assay. The activities of MMP‐2 and MMP‐9 were investigated using gelatin zymography. At the end of each incubation, changes in loss of dry mass and CC‐mediated or to...
Source: European Journal of Oral Sciences - November 10, 2018 Category: Dentistry Authors: Pinar Altinci,
Murat Mutluay,
Leo Tj äderhane,
Arzu Tezvergil‐Mutluay Tags: Original Article Source Type: research
Effect of methacrylated chitosan incorporated in experimental composite and adhesive on mechanical properties and biofilm formation
This study aimed to investigate the effect of methacrylated chitosan (CH‐MA), incorporated into the polymeric network of an experimental dental composite and adhesive, on biofilm growth ofStreptococcus mutans and to assess the mechanical properties of the modified materials. The methacrylation of low ‐molecular‐weight chitosan was achieved and biofilm studies confirmed the antibacterial effect of the modified polymer in solution. Methacrylated chitosan was incorporated into an experimental composite and adhesive, and the modified materials reduced the formation ofS. mutans biofilm. The incorporation of CH ‐MA did...
Source: European Journal of Oral Sciences - November 9, 2018 Category: Dentistry Authors: Ida S. R. Stenhagen,
H åkon V. Rukke,
Inger S. Dragland,
Hilde M. Kopperud Tags: Original article Source Type: research
