Editorial board
Publication date: October 2019Source: European Psychiatry, Volume 62Author(s): (Source: European Psychiatry)
Source: European Psychiatry - November 2, 2019 Category: Psychiatry Source Type: research

Diagnostic stability and long-term symptomatic and functional outcomes in first-episode antipsychotic-naïve patients with schizophrenia
ConclusionWe confirm the emerging evidence of a decreasing long-term diagnostic stability of schizophrenia, and a protective role of female sex. The association between premorbid intelligence and symptomatic remission underscores the pertinence of including cognitive deficits in the diagnostic category of schizophrenia. The association between younger age at diagnosis and symptomatic remission may reflect positive effects of early detection or a drift in the interpretation of the diagnostic classification system. (Source: European Psychiatry)
Source: European Psychiatry - October 12, 2019 Category: Psychiatry Source Type: research

Insulin-signaling abnormalities in drug-naïve first-episode schizophrenia: Transduction protein analyses in extracellular vesicles of putative neuronal origin
ConclusionThese findings support the hypothesis of neuronal insulin resistance in DNFES, small sample sizes notwithstanding. The counterintuitive trend towards reduced pS312-IRS-1 in DNFES may result from adaptive feedback mechanisms. The observed changes in insulin signaling could be clinically meaningful as suggested by their association with higher PANSS scores. (Source: European Psychiatry)
Source: European Psychiatry - October 5, 2019 Category: Psychiatry Source Type: research

Associations of psychosis-risk symptoms with quality of life and self-rated health in the Community
ConclusionsWhen present, CHR, in particular basic symptoms are already distressful for individuals of the community and associated with poorer subjective QoL and health. Therefore, the symptoms are clinically relevant by themselves, even when criteria for a CHR state are not fulfilled. Yet, unlike affective and anxiety disorders, CHR symptoms seem to have no long-term influence on QoL and SRH. (Source: European Psychiatry)
Source: European Psychiatry - October 4, 2019 Category: Psychiatry Source Type: research

Family history of alcohol use disorder is associated with brain structural and functional changes in healthy first-degree relatives
ConclusionsFamily history of alcohol use disorder is linked to structural and functional variations including brain regions involved in reward processes. (Source: European Psychiatry)
Source: European Psychiatry - September 25, 2019 Category: Psychiatry Source Type: research

Correlates of current rapid-cycling bipolar disorder: Results from the Italian multicentric RENDiBi study
ConclusionsRC in BD seems to be more prevalent in female gender and associated with some unfavorable clinical features, such as an increased risk of hospitalization. These aspects should be taken into account in the management and monitoring of RC versus non-RC patients. (Source: European Psychiatry)
Source: European Psychiatry - September 22, 2019 Category: Psychiatry Source Type: research

Trajectories and determinants of functional limitations in late-life depression: A 2-year prospective cohort study
Conclusions1 in 5 depressed older patients have a course with functional recovery. Combining functional and symptomatic recovery points to a subgroup of older patients that might profit from more rigorous psychiatric treatment targeted at psychiatric comorbidity and a group of frail depressed older patients that might profit from integrated geriatric rehabilitation. (Source: European Psychiatry)
Source: European Psychiatry - September 22, 2019 Category: Psychiatry Source Type: research

Electroretinography in psychiatry: A systematic literature review
Publication date: October 2019Source: European Psychiatry, Volume 62Author(s): Peter Youssef, Siddharth Nath, Gary A Chaimowitz, Sebastien S. PratAbstractThis review aims to consolidate the available information on use of electroretinography as a diagnostic tool in psychiatry. The electroretinogram (ERG) has been found to have diagnostic utility in cocaine withdrawal (reduced light-adapted b-wave response), major depressive disorder (reduced contrast gain in pattern ERG), and schizophrenia (reduced a- and b-wave amplitudes). This review examines these findings as well as the applicability of ERG to substance use disorder, ...
Source: European Psychiatry - September 22, 2019 Category: Psychiatry Source Type: research

Accuracy of psychometric tools in the assessment of personality in adolescents and adults requesting gender-affirming treatments: A systematic review
ConclusionThere are no agreed reference standards for this population and psychometric tools continue to be scored on reference data from the cisgender (not transgender) population. We need robust evidence on this issue, as individuals may be denied access to gender affirming treatments based on psychometric tools without established reliability in this population. (Source: European Psychiatry)
Source: European Psychiatry - September 21, 2019 Category: Psychiatry Source Type: research

Association between circulating zinc/ferritin levels and parent Conner’s scores in children with attention deficit hyperactivity disorder
Conclusion, Zinc supplements in adjuvant to the main treatment significantly improved symptoms of ADHD children. However, a combined zinc and iron supplements was superior to zinc alone in alleviating ADHD symptoms as well as IQ improvement. (Source: European Psychiatry)
Source: European Psychiatry - September 21, 2019 Category: Psychiatry Source Type: research

The effect of the Suicide Prevention Program (SPP) on the characteristics of Israeli soldiers who died by suicide after its implementation
ConclusionsWhile the SPP succeeded in reducing risk of suicide in situational factors, dispositional risk factors were not affected by the SPP. The OR decreased in critical masses and rose in unique and smaller groups. (Source: European Psychiatry)
Source: European Psychiatry - September 21, 2019 Category: Psychiatry Source Type: research

Atypical antipsychotics for Attention-Deficit/Hyperactivity disorder- science, art, or fad?
Publication date: October 2019Source: European Psychiatry, Volume 62Author(s): Ahmed Naguy, Mohamed S Hashem, Sulaiman AlKhadhar (Source: European Psychiatry)
Source: European Psychiatry - September 20, 2019 Category: Psychiatry Source Type: research

Perceived discrimination and psychotic experiences in the English general population
ConclusionDifferent forms of discrimination are associated with PEs in the general population. As discrimination is common at the societal level, this highlights the importance of public policy and evidence-based interventions to reduce discrimination and improve population mental health. (Source: European Psychiatry)
Source: European Psychiatry - September 15, 2019 Category: Psychiatry Source Type: research

Transcranial direct current stimulation in patients with obsessive compulsive disorder: A randomized controlled trial
ConclusionDespite significant acute effects, tDCS with the cathode placed over the left OFC and the anode placed over the right cerebellum was not significantly effective in inducing a long-lasting reduction of symptoms in patients with treatment-resistant OCD. (Source: European Psychiatry)
Source: European Psychiatry - September 14, 2019 Category: Psychiatry Source Type: research

Subjective response to antipsychotics in bipolar disorders: A review of a neglected area
ConclusionsThere is an asymmetry between the increase in the use of antipsychotics in BD and the lack of data regarding the SRA. Phenomenologically, SRA in BD is similar to that found in schizophrenic subjects. Some of these symptoms may be misdiagnosed as depressive symptoms. The existing data show that SRA has a strong correlation with treatment compliance as well as a promising way to develop theoretical paradigms for these disorders. (Source: European Psychiatry)
Source: European Psychiatry - September 14, 2019 Category: Psychiatry Source Type: research