Prolonged depression of knee ‐extensor torque complexity following eccentric exercise
New FindingsWhat is the central question of this study?Does eccentric exercise leading to prolonged knee ‐extensor torque depression also result in a prolonged loss of knee‐extensor torque complexity?What is the main finding and its importance?The recovery of the loss of torque complexity after eccentric exercise took 24  h, whereas after acute muscle fatigue it took 10 min. The depression of torque complexity after eccentric exercise was prolonged.AbstractNeuromuscular fatigue reduces the temporal structure, or complexity, of muscle torque output. Exercise ‐induced muscle damage reduces muscle torque output for co...
Source: Experimental Physiology - November 28, 2018 Category: Physiology Authors: Jamie Pethick, Katherine Whiteaway, Samantha L. Winter, Mark Burnley Tags: RESEARCH PAPER Source Type: research

Messages from the auricle ‐ limiting progression of heart failure with preserved ejection fraction through transcutaneous nerve stimulation of nerves in the external ear
Experimental Physiology, Volume 0, Issue ja, -Not available-. (Source: Experimental Physiology)
Source: Experimental Physiology - November 27, 2018 Category: Physiology Authors: Beatrice Bretherton, Susan Deuchars, Jim Deuchars Tags: VIEWPOINT Source Type: research

Ventilatory constraints influence physiological dead space in heart failure
New FindingsWhat is the central question of this study?The goal of this study was to investigate the effect of alterations in tidal volume and alveolar volume on the elevated physiological dead space and the contribution of ventilatory constraints thereof in heart failure patients during submaximal exercise.What is the main finding and its importance?We found that physiological dead space was elevated in heart failure via reduced tidal volume and alveolar volume. Furthermore, the degree of ventilatory constraints was associated with physiological dead space and alveolar volume.AbstractPatients who have heart failure with r...
Source: Experimental Physiology - November 23, 2018 Category: Physiology Authors: Joshua R. Smith, Thomas P. Olson Tags: RESEARCH PAPER Source Type: research

Evidence of high 18F ‐Fluorodeoxyglucose uptake in the subcutaneous adipose tissue of the dorsocervical area in young adults
This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 23, 2018 Category: Physiology Authors: Borja Martinez ‐Tellez, Guillermo Sanchez‐Delgado, Juan M.A. Alcantara, Francisco M. Acosta, Francisco J. Amaro‐Gahete, Francisco J. Osuna‐Prieto, Alejandro Perez‐Bey, David Jimenez‐Pavon, Jose M. Llamas‐Elvira, Angel Gil, Concepci Tags: SHORT COMMUNICATION Source Type: research

The magnitude of neuromuscular fatigue is not intensity ‐dependent when cycling above critical power but relates to aerobic and anaerobic capacities
This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 23, 2018 Category: Physiology Authors: Lisa U. Sch äfer, Mark Hayes, Jeanne Dekerle Tags: RESEARCH PAPER Source Type: research

Ventilatory constraints influence physiological dead space in heart failure
New FindingsWhat is the central question of this study?The goal of this study was to investigate the effect of alterations in tidal volume and alveolar volume on the elevated physiological dead space and the contribution of ventilatory constraints thereof in heart failure patients during submaximal exercise.What is the main finding and its importance?We found that physiological dead space was elevated in heart failure via reduced tidal volume and alveolar volume. Furthermore, the degree of ventilatory constraints was associated with physiological dead space and alveolar volume.AbstractPatients who have heart failure with r...
Source: Experimental Physiology - November 23, 2018 Category: Physiology Authors: Joshua R. Smith, Thomas P. Olson Tags: RESEARCH PAPER Source Type: research

Evidence of high 18F ‐Fluorodeoxyglucose uptake in the subcutaneous adipose tissue of the dorsocervical area in young adults
This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 23, 2018 Category: Physiology Authors: Borja Martinez ‐Tellez, Guillermo Sanchez‐Delgado, Juan M.A. Alcantara, Francisco M. Acosta, Francisco J. Amaro‐Gahete, Francisco J. Osuna‐Prieto, Alejandro Perez‐Bey, David Jimenez‐Pavon, Jose M. Llamas‐Elvira, Angel Gil, Concepci Tags: SHORT COMMUNICATION Source Type: research

The magnitude of neuromuscular fatigue is not intensity ‐dependent when cycling above critical power but relates to aerobic and anaerobic capacities
This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 23, 2018 Category: Physiology Authors: Lisa U. Sch äfer, Mark Hayes, Jeanne Dekerle Tags: RESEARCH PAPER Source Type: research

Smoking during pregnancy increases chemerin expression in neonatal tissue
We examined chemerin gene expression [n = 31 non‐smoker (NS) and 15 smoker (S)] and DNA methylation (n = 28 NS andn = 11 S) in skin collected from babies born to mothers who smoked during pregnancy as compared to non‐smoking controls. Quality RNA and DNA were isolated from foreskin tissue following circumcision, and chemerin gene expression and DNA methylation were assessed. Further, in a second cohort, we ut ilized primary dermal foreskin fibroblasts as a functional measure of adipogenesis in living cells (n = 11 NS andn = 8 S). Cells were stimulated with an adipogenic cocktail, mRNA was isolated from cells after...
Source: Experimental Physiology - November 22, 2018 Category: Physiology Authors: Leryn J. Reynolds, Niraj R. Chavan, Logan B. DeHoff, Joshua D. Preston, Hannah F. Maddox, John M. O'Brien, David A. Armstrong, Carmen J. Marsit, Kevin J. Pearson Tags: RESEARCH PAPER Source Type: research

Humans: A homeothermic animal that needs perturbation?
Experimental Physiology, Volume 0, Issue ja, -Not available-. (Source: Experimental Physiology)
Source: Experimental Physiology - November 22, 2018 Category: Physiology Authors: Mike Tipton Tags: EDITORIAL Source Type: research

Impairment of rat esophageal muscle contractility associated with experimental non ‐erosive esophageal mucosal damage
This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 22, 2018 Category: Physiology Authors: Kalinne Kelly Lima Gadelha, Francisco Jos é Batista‐Lima, Daniel Maia Nogueira Oliveira, Emanuella Feitosa de Carvalho, Daniel Sifrim, Armênio Aguiar dos Santos, Pedro Jorge Caldas Magalhães Tags: RESEARCH PAPER Source Type: research

Plasma asymmetric dimethylarginine concentrations are not related to differences in maximal oxygen uptake in endurance trained and untrained men
ConclusionExercise capacity and microvascular O2 delivery are not related to plasma ADMA concentrations in young healthy male subjects. Our findings show that ADMA does not play a crucial role in local muscle perfusion and in maintaining exercise capacity without pathological conditions.This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 22, 2018 Category: Physiology Authors: Mehdi Pawlak ‐Chaouch, Julien Boissière, Désiré Munyaneza, Semah Tagougui, François‐Xavier Gamelin, Grégory Cuvelier, Elsa Heyman, Jean‐François Goossens, Amandine Descat, Serge Berthoin, Julien Aucouturier Tags: Research Paper Source Type: research

Smoking during pregnancy increases chemerin expression in neonatal tissue
We examined chemerin gene expression [n = 31 non‐smoker (NS) and 15 smoker (S)] and DNA methylation (n = 28 NS andn = 11 S) in skin collected from babies born to mothers who smoked during pregnancy as compared to non‐smoking controls. Quality RNA and DNA were isolated from foreskin tissue following circumcision, and chemerin gene expression and DNA methylation were assessed. Further, in a second cohort, we ut ilized primary dermal foreskin fibroblasts as a functional measure of adipogenesis in living cells (n = 11 NS andn = 8 S). Cells were stimulated with an adipogenic cocktail, mRNA was isolated from cells after...
Source: Experimental Physiology - November 22, 2018 Category: Physiology Authors: Leryn J. Reynolds, Niraj R. Chavan, Logan B. DeHoff, Joshua D. Preston, Hannah F. Maddox, John M. O'Brien, David A. Armstrong, Carmen J. Marsit, Kevin J. Pearson Tags: RESEARCH PAPER Source Type: research

Humans: A homeothermic animal that needs perturbation?
Experimental Physiology, Volume 0, Issue ja, -Not available-. (Source: Experimental Physiology)
Source: Experimental Physiology - November 22, 2018 Category: Physiology Authors: Mike Tipton Tags: EDITORIAL Source Type: research