FEMS Immunology and Medical Microbiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Issue Information
(Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - November 6, 2014 Category: Microbiology Tags: Issue Information Source Type: research

Is the hoopla over CPAF justified?
(Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - September 15, 2014 Category: Microbiology Authors: Georg Häcker, Dagmar Heuer, David M. Ojcius Tags: Commentary Source Type: research

Pseudomonas aeruginosa AmpR: an acute–chronic switch regulator
Abstract Pseudomonas aeruginosa is one of the most intractable human pathogens that pose serious clinical challenge due to extensive prevalence of multidrug‐resistant clinical isolates. Armed with abundant virulence and antibiotic resistance mechanisms, it is a major etiologic agent in a number of acute and chronic infections. A complex and intricate network of regulatory factors dictates the expression of pathogenicity factors in P. aeruginosa. Some proteins within the network play key roles and control multiple pathways. This review discusses the role of one such protein, AmpR, which was initially recognized for its r...
Source: FEMS Immunology and Medical Microbiology - September 3, 2014 Category: Microbiology Authors: Deepak Balasubramanian, Hansi Kumari, Kalai Mathee Tags: MiniReview Source Type: research

An H1 ‐H3 chimeric influenza virosome confers complete protection against lethal challenge with PR8 (H1N1) and X47 (H3N2) viruses in mice
Abstract Annual health threats and economic damages caused by influenza virus are still a main concern of the World Health Organization and other health departments all over the world. An influenza virosome is a highly efficient immunomodulating carrier mimicking the natural antigen presentation pathway and has shown an excellent tolerability profile due to its biocompatibility and purity. The major purpose of this study was to construct a new chimeric virosome influenza vaccine containing hemagglutinin (HA) and neuraminidase (NA) proteins derived from the A/PR/8/1934 (H1N1) (PR8) and A/X/47 (H3N2) (X47) viruses, and to ev...
Source: FEMS Immunology and Medical Microbiology - August 31, 2014 Category: Microbiology Authors: Asghar Abdoli, Hoorieh Soleimanjahi, Masoumeh Tavassoti Kheiri, Abbas Jamali, Vahideh Mazaheri, Meghdad Abdollahpour Alitappeh Tags: Research Article Source Type: research

Is the hoopla about CPAF justified?
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 11, 2014 Category: Microbiology Authors: Georg Häcker, David M. Ojcius, Dagmar Heuer Tags: Commentary Source Type: research

Issue Information
(Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 11, 2014 Category: Microbiology Tags: Issue Information Source Type: research

Development of imaging techniques to study the pathogenesis of biosafety level 2/3 infectious agents
Abstract Despite significant advances in microbiology and molecular biology over the last decades, several infectious diseases remain global concerns, resulting in the death of millions of people worldwide each year. According to the Center for Disease Control (CDC) in 2012, there were 34 million people infected with HIV, 8.7 million new cases of tuberculosis, 500 million cases of hepatitis, and 50–100 million people infected with dengue. Several of these pathogens, despite high incidence, do not have reliable clinical detection methods. New or improved protocols have been generated to enhance detection and quantitat...
Source: FEMS Immunology and Medical Microbiology - August 11, 2014 Category: Microbiology Authors: Courtney E. Rella, Nancy Ruel, Eliseo A. Eugenin Tags: Research Article Source Type: research

CD4+/CD25+ T cells suppress autologous CD4+/CD25− lymphocytes and secrete granzyme B during acute and chronic hepatitis C
Abstract We aimed to verify whether CD4+/CD25+ T cells suppress CD4+ T cells and secrete Granzyme B (GZB) during acute and chronic hepatitis C (CHC) infection. We enrolled 50 subjects: 20 patients with CHC (Group A), 15 healthy individuals (Group B), 10 patients with acute hepatitis C later evolved to persistent infection (Group C) and five patients who resolved hepatitis C virus infection during acute phase (Group D). We analysed, on enrolled subjects CD4+/CD25+ T cells and related GZB production as well as Annexin V activity. Patients from Groups A and C had higher frequency and function of peripheral Treg cells than hea...
Source: FEMS Immunology and Medical Microbiology - August 11, 2014 Category: Microbiology Authors: Alessandro Perrella, Anna D'Antonio, Costanza Sbreglia, Paolo Sorrentino, Paolo Conca, Luigi Atripaldi, Pio Conti, Oreste Perrella Tags: Research Article Source Type: research

The Mycobacterium tuberculosis recombinant LprN protein of mce4 operon induces Th ‐1 type response deleterious to protection in mice
Abstract Lipoproteins are known to be effective immunogens and affect both innate and adaptive immunity. The lprN gene of Mycobacterium tuberculosis has been predicted to encode for a putative lipoprotein in silico. Here, we studied its function as an immunogen by in vivo studies in mice. The recombinant LprN protein, expressed and purified in Escherichia coli, triggered a cell‐mediated immune response in BALB/c mice. This was observed by significantly higher T‐cell proliferation and increased production of TNF‐α and IFN‐γ cytokines. However, pre‐exposure to LprN protein failed to provide protection in mice aft...
Source: FEMS Immunology and Medical Microbiology - August 6, 2014 Category: Microbiology Authors: Rashmi Pasricha, Neeraj K. Saini, Nisha Rathor, Rakesh Pathak, Rajesh Sinha, Mandira Varma ‐Basil, Kiran Mishra, Vani Brahmachari, Mridula Bose Tags: Research Article Source Type: research

Replication of type 5 adenovirus promotes middle ear infection by Streptococcus pneumoniae in the chinchilla model of Otitis media
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 1, 2014 Category: Microbiology Authors: Kyle A. Murrah, Roberta L. Turner, Bing Pang, Antonia C. Perez, Jennifer L. Reimche, Lauren B. King, John Wren, Uma Gandhi, W. Edward Swords, David A. Ornelles Tags: Research Paper Source Type: research

Cellular interaction of nontypeable Haemophilus influenzae triggers cytotoxicity of infected Type II alveolar cells via apoptosis
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 1, 2014 Category: Microbiology Authors: Manu Goyal, Meenu Singh, Pallab Ray, Radhika Srinivasan, Anuradha Chakraborti Tags: Research Paper Source Type: research

Analysis of cell surface alterations in Legionella pneumophila cells treated with human apolipoprotein E
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 1, 2014 Category: Microbiology Authors: Marta Palusinska‐Szysz, Agnieszka Zdybicka‐Barabas, Małgorzata Cytryńska, Sylwia Wdowiak‐Wróbel, Elżbieta Chmiel, Wiesław I. Gruszecki Tags: Research Paper Source Type: research

The Chlamydia protease CPAF: Caution, Precautions And Function
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 1, 2014 Category: Microbiology Authors: Ming Tan, Christine Sütterlin Tags: Commentary Article Source Type: research

Evaluation of antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection: tetracycline versus tetracycline plus rifampicin
This article is protected by copyright. All rights reserved. (Source: FEMS Immunology and Medical Microbiology)
Source: FEMS Immunology and Medical Microbiology - August 1, 2014 Category: Microbiology Authors: Annette Prohl, Markus Lohr, Carola Ostermann, Elisabeth Liebler‐Tenorio, Angela Berndt, Wieland Schroedl, Michael Rothe, Evelyn Schubert, Konrad Sachse, Petra Reinhold Tags: Research Paper Source Type: research