The stratified effects of repetitive transcranial magnetic stimulation in upper limb motor impairment recovery after stroke: a meta-analysis
ConclusionThe effectiveness of rTMS depends on its parameters, severity of hemiplegia, and stroke stages. It is important to consider all these factors together, as any single grouping method is incomplete. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
The greatest loss of unpleasant smells may be related to the risk of more severe PD symptoms
ConclusionOur results emphasize the link between olfactory impairment of specific emotional valence, neutral/unpleasant odors, and PD severity, particularly with respect to akinetic-rigid symptoms. A concise olfactory test that focuses on both neutral and unpleasant odors may offer deeper insights into PD symptoms. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
Global research trends and hotspots of artificial intelligence research in spinal cord neural injury and restoration —a bibliometrics and visualization analysis
ConclusionWe pinpointed three research hotspots for AI research in spinal cord neural injury and restoration: (1) intelligent robots and limb exoskeletons to assist rehabilitation training; (2) brain-computer interfaces; and (3) neuromodulation and noninvasive electrical stimulation. In addition, many new hotspots were discussed: (1) starting with image segmentation models based on convolutional neural networks; (2) the use of AI to fabricate polymeric biomaterials to provide the microenvironment required for neural stem cell-derived neural network tissues; (3) AI survival prediction tools, and transcription factor regulat...
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
The effect of cognitive rehabilitation on daily functioning of patients with Alzheimer ’s disease: a systematic review and meta-analysis of clinical trials
ConclusionCognitive rehabilitation exhibited a moderate to large impact on both quality of life and occupational performance levels in people with AD. Future studies are required to explore the potential of various cognitive interventions across specific domains, so as to provide more insights into the management of AD.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023444390. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
Therapeutic singing-induced swallowing exercise for dysphagia in advanced-stage Parkinson ’s disease
ConclusionTherapeutic singing exercises may help maintain swallowing function in advanced PD patients, potentially enhancing quality of life related to swallowing in those with advanced-stage diseases.Clinical trial registrationhttps://cris.nih.go.kr/cris/search/listDetail.do, identifier KCT0008644. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
Machine learning applied to epilepsy: bibliometric and visual analysis from 2004 to 2023
ConclusionsThis study is the first to use bibliometric methods to visualize and analyze research in areas related to the application of machine learning in epilepsy, revealing research trends and frontiers in the field. This information will provide a useful reference for epilepsy researchers focusing on machine learning. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
Dual effects of serum urate on stroke risk and prognosis: insights from Mendelian randomization
ConclusionThis study supports the dual role of genetically predicted SUA in increasing stroke risk, especially ischemic stroke risk, and in improving functional outcome and motor recovery. SBP and DBP are key mediators lying on the causal pathways of SUA with AS and IS. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
A bibliometric analysis of cerebral palsy from 2003 to 2022
ConclusionThis study provides a systematic and comprehensive analysis of the CP-related literature. It reveals that Developmental Medicine and Child Neurology is the most active journal in this field. The USA, Vrije Universiteit Amsterdam, and Boyd are the top countries, institutions, and authors, respectively. Emerging treatment methods, complication management, and functional recovery comprise the future research directions and potential topic hotspots for CP. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
Associations of apolipoprotein E ε4 allele, regional cerebral blood flow, and serum liver function markers in patients with cognitive impairment
ConclusionAPOE4 exerts a strong effect on CBF dysfunction by inheritance, representing a risk factor for AD. APOE4 may be related to bilirubin metabolism, potentially providing specific neural targets for the diagnosis and treatment of AD. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - April 2, 2024 Category: Neurology Source Type: research
Catgut embedding in acupoints combined with repetitive transcranial magnetic stimulation for the treatment of postmenopausal osteoporosis: study protocol for a randomized clinical trial
DiscussionCEA achieves brain-bone mass regulation through the bottom-up way of peripheral-central while rTMS achieves it through the top-down stimulation of central-peripheral. CEA combined with rTMS can stimulate the peripheral-central at the same time and promote peripheral bone mass formation. The combination of CEA and rTMS may play a coordinating, synergistic, and side-effect-reducing role, which is of great clinical significance in exploring better treatment options for PMOP.Clinical trial registration: https://www.chictr.org.cn/, identifier ChiCTR2300073863. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research
Endovascular treatment of intracranial internal carotid artery bifurcation region aneurysms
Intracranial internal carotid artery (ICA) bifurcation region aneurysms are uncommon. When treatment is necessary for ICA, endovascular treatment (EVT) can be a useful option. Due to the complexity of these aneurysms and the variability of EVT techniques, EVT for ICA bifurcation aneurysms is challenging. Currently, it is necessary to perform a review to explore this issue further. In this review, the following issues were discussed: the anatomy of the ICA bifurcation region; the classification, natural history and EVT status of ICA bifurcation region aneurysms; the technique used for identifying ICA bifurcation region aneu...
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research
Safety and efficacy of magnesium-rich artificial cerebrospinal fluid for subarachnoid hemorrhage
ConclusionUsing MACSF as an irrigation fluid for aneurysm clipping can significantly improve the 90-day prognosis of patients with aSAH, which may be related to the reduced incidence of CVS.Clinical trial registrationhttps://www.clinicaltrials.gov, identifier NCT04358445. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research
Case report: A cystic capillary hemangioma located at the conus medullaris mimicking hemangioblastoma
We report a rare case of intradural extramedullary capillary hemangioma at the conus medullaris in a 66-year-old female patient. Our initial diagnosis leaned towards a cystic hemangioblastoma based on MRI findings due to the presence of cystic formation with an enhanced mural nodule. However, surgical exploration and subsequent pathological examination revealed the lesion as a capillary hemangioma. To the authors’ knowledge, this case may represent the first documented instance of a spinal capillary hemangioma that mimics a cystic hemangioblastoma. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research
Altered volume of the amygdala subregions in patients with chronic low back pain
ConclusionOur study suggests that the left Ce and left Co may be involved in the pathophysiological processes of CLBP. Moreover, the volume of the left Ce may be a biomarker for detecting the risk of CLBP. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research
Peripapillary hyperreflective ovoid mass-like structures: multimodal imaging and associated diseases
Growing evidence has demonstrated that peripapillary hyperreflective ovoid mass-like structures (PHOMS) are novel structures rather than a subtype of optic disc drusen. They correspond to the laterally bulging herniation of optic nerve fibers and are believed to be the marker of axoplasmic stasis. PHOMS present in a broad spectrum of diseases, including optic disc drusen, tilted disc syndrome, papilloedema, multiple sclerosis, non-arteritic anterior ischemic optic neuropathy, optic neuritis, Leber hereditary optic neuropathy, and so on. We focus on the multimodal imaging features, pathophysiological mechanisms of PHOMS, an...
Source: Frontiers in Neurology - March 28, 2024 Category: Neurology Source Type: research
