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Therapeutic potential of phosphoethanolamine-bound C-reactive protein in atherosclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 599-602.
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Biology of LOX-1 in relation to atherogenesisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 689-696. LOX-1, a lectin-like 52 kD receptor for oxidized LDL, is present primarily on endothelial cells. It has been linked to endothelial dysfunction, inflammation and oxidative stress. LOX-1 activation has also been linked to collagen formation, a key component ...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Augmentation of the renin–angiotensin system by hypercholesterolemia promotes vascular diseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 625-636. Activation of the renin–angiotensin system (RAS) and aberrant cholesterol metabolism have generally been considered as independent mechanisms in the development of several vascular diseases. However, it is becoming increasingly apparent in both human and ...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Sphingosine-1-phosphate synthesis and functions in mast cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 665-674. Sphingolipids are not only major lipid components of all eukaryotic cell membranes, but they also comprise an important family of bioactive signaling molecules that regulate a diverse array of biological responses. The sphingolipid metabolite sphingosine-...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Sex hormones and circulating lipoprotein levelsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 603-606.
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Bulletin BoardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 607-609.
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

AcknowledgementsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 709-709.
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Oxidized LDL and the metabolic syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 637-649. The metabolic syndrome is a common and complex disorder combining obesity, dyslipidemia, hypertension and insulin resistance. It is associated with a high cardiovascular risk that can only partially be explained by its components. There is evidence that ...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Lipidology: bridge between basic science and clinical pathologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 611-623. The 49th meeting of the International Conference for the Bioscience of Lipids (ICBL) was convened at the end of August 2008 in the historic city of Maastricht in The Netherlands. The meeting organizers (Jan Glatz, Joost Luiken and Edouard Bevers) crafted ...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Uncontrolled airway inflammation in lung disease represents a defect in counter-regulatory signalingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 697-704. Counter-regulatory lipid mediators are generated during airway inflammation to promote resolution. Defects in the production of these lipid mediators have now been associated with several diseases of persistent airway inflammation. Lipoxins are the lead ...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Insulin resistance and lipid disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 651-664. The dyslipidemia of insulin resistance is characterized by elevated levels of triglycerides (TGs), low HDL-cholesterol and small dense LDL particles. Many of these features are affected by the reduction in insulin sensitivity, with a central role played ...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Role of the ABC transporters ABCA1 and ABCG1 in foam cell formation and atherosclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , December 2008, Vol. 3, No. 6, Pages 675-687. Enhancing reverse cholesterol transport from macrophages in the arterial wall to the liver for biliary excretion has been identified as a potential therapeutic strategy to reduce and eventually regress atherogenesis. In addition to HDL-raising therapies, ...
Source: Future Lipidology - November 28, 2008 Category: Lipidology Tags: article Source Type: journals

Intestinal postprandial chylomicrons: state of the union between liver, gut and dyslipidemia?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 473-480.
Source: Future Lipidology - September 26, 2008 Category: Lipidology Tags: article Source Type: journals

Dissecting NPC1L1-mediated cholesterol absorptionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 481-484.
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Long-term effects of trans fatty acid intake during pregnancy and lactation: does it have deleterious consequences?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 489-494. Evaluation of: Pisani LP, Oller do Nascimento CM, Bueno AA et al.: Hydrogenated fat diet intake during pregnancy and lactation modifies the PAI-1 gene expression in white adipose tissue of offspring in adult life. Lipids Health Dis. 7, 13 (2008). ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Effect of exercise on lipolysis in adipose tissueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 557-572. Adipose tissue is a major source of nonesterified fatty acids, which are involved in the etiopathogenesis of several metabolic diseases. Mechanisms regulating the processes of lipolysis are of major importance because they represent potential drug ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Apolipoprotein E and cholesterol in aging and disease in the brainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 505-530. Cholesterol can be detrimental or vital, and must be present in the right place at the right time and in the right amount. This is well known in the heart and the vascular system. However, in the CNS cholesterol is still an enigma, although several of ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Apolipoprotein M: structure and functionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 495-503. Lipoproteins in blood play an important physiological role transporting cholesterol, lipids and lipid-soluble substances to the different organs of the body. Diseases such as atherosclerosis, cardiovascular disease and stroke are associated with defects ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

DHCR7 mutations causing the Smith–Lemli–Opitz syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 585-593. The Smith–Lemli–Opitz Syndrome (SLOS) is a metabolic malformation and mental retardation syndrome that is casued by a defect in cholesterol biosynthesis. The resulting loss of cholesterol leads to a spectrum from mild to very severe phenotype. The DHCR7 ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Macrophage infiltration into adipose tissue: initiation, propagation and remodelingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 545-556. It has long been known that adipose tissue in obesity is in a heightened state of inflammation. Recently, our understanding of this has been transformed by the knowledge that immune cells such as macrophages and T cells can infiltrate adipose tissue and ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Bulletin BoardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 485-487.
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Postprandial triglyceride-rich lipoproteins in insulin resistance and Type 2 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 531-543. Recent evidence from prospective epidemiological large-scale studies have provided convincing proof for the role of nonfasting triglycerides, carried in VLDL and chylomicrons, as an independent risk factor for cardiovascular disease and death. ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

AcknowledgementsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 597-597.
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Nutritional management of lipids for overweight and obesity: what can we achieve?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , October 2008, Vol. 3, No. 5, Pages 573-584. Overweight and obesity are independent risk factors for cardiovascular disease. Many cardiovascular disease risk factors are elevated in overweight and obese individuals, including dyslipidemia and inflammation, among others. Current dietary ...
Source: Future Lipidology - September 25, 2008 Category: Lipidology Tags: article Source Type: journals

Clinical trials and surrogate end points: lessons from the ENHANCE trialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 353-357.
Source: Future Lipidology - July 17, 2008 Category: Lipidology Tags: article Source Type: journals

In vivo versus cell culture models: the example of lipid biosynthesis in the enterocyteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report reviews the ...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Sex-dependent differences in lipid handling and the implications for obesity-linked disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 359-361.
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Structure and function of the enigmatic Sec14 domain-containing proteins and the etiology of human diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 399-410. Proteins containing the Sec14 domain, also referred to as the CRAL-TRIO domain, are found throughout Eukarya. Sec14 domains bind a single lipophilic molecule with the hydrophobic tail oriented toward the middle of the protein and the hydrophilic head ...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Risk of metabolic and vascular disease in South Asians: potential mechanisms for increased insulin resistanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 411-424. The impending global pandemic of obesity, Type 2 diabetes and vascular disease suggests an urgent need for prevention strategies. Of all the common ethnic groups, South Asians, who make up a fifth of the world’s population, experience the highest ...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Roles of eicosanoids in prostate cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 453-467. Arachidonic acid (AA) is metabolized by oxygenases to numerous biologically active eicosanoids. For example, AA is metabolized by COX to prostaglandins (PGs) and thromboxanes, by lipoxygenases (LOX) to leukotrienes and hydroxyeicosatetraenoic acids (...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Apolipoprotein AV: gene expression, physiological role in lipid metabolism and clinical relevanceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 371-384. The apolipoprotein APOA5 gene, a member of the gene cluster on chromosome 11q23 that includes APOA1, APOC3 and APOA4, has gained considerable interest as it encodes ApoAV, a key determinant of circulating levels of potentially atherogenic triglyceride-...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Role of lipoprotein lipase in triglyceride metabolism: potential therapeutic targetEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 385-397. Moderately elevated plasma triglyceride levels contribute to increased risk for cardiovascular disease, whereas severe hypertriglyceridemia (fasting plasma triglyceride >10 mmol/l) is associated with an increased risk of pancreatitis. The enzyme ...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Researchers identify the role of the XBP1 transcription factor in cholesterol production in the liverEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 363-365.
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Ganglioside complexes as target antigens in Guillain–Barré syndrome and related disordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 425-434. Recent data demonstrate that sera from patients with Guillain–Barré syndrome react with ganglioside complexes (GSCs) consisting of two different gangliosides, but not with each constituent ganglioside. GSCs are likely to express conformationally ...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

The ins and outs of endocannabinoid signaling in healthy and diseased brainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 435-452. The endocannabinoid signaling system regulates neuronal activity and glial cell function. While numerous studies exist on the pharmacology and coupling of cannabinoid receptors, only recently have fundamental questions been addressed regarding ...
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

AcknowledgementsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , August 2008, Vol. 3, No. 4, Pages 471-471.
Source: Future Lipidology - July 16, 2008 Category: Lipidology Tags: article Source Type: journals

Myriocin as an atherosclerosis inhibitorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 221-224.
Source: Future Lipidology - May 20, 2008 Category: Lipidology Tags: article Source Type: journals

Evaluation of phospholipid transfer protein as a therapeutic targetEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 327-335. Phospholipid transfer protein (PLTP) plays an essential role in lipoprotein metabolism. Deficiency or overexpression of PLTP in animal models results in modulation of the atherosclerotic process. Moreover, PLTP has also been implicated in obesity and ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Colesevelam hydrochloride: a specifically engineered bile acid sequestrantEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 237-255. There is a well established association between serum cholesterol and coronary heart disease and this relationship has been found to be related to concentration and is continuous over the entire distribution of cholesterol levels. Recent studies have ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Fatty liver and HDL-cholesterol: just a matter of quantity?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 225-227.
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Status of cardiolipin synthesis in heart failureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 311-317. Phospholipids are important structural and functional components of all biological membranes. The mitochondrial phospholipid, cardiolipin, comprises approximately 15% of the entire phospholipid mass of the heart. Cardiolipin plays an important role in ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

The case against ApoB and the ApoB:ApoA-I ratio: are they right?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 257-264. Based on similar predictive powers, the investigators of the Framingham Offspring Study concluded that the total cholesterol:HDL-cholesterol and the ApoB:ApoA-I ratios were equivalent markers of cardiovascular risk. Since the apolipoprotein ratio offered ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Statins in stroke preventionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 319-325. Beside blood pressure-lowering drugs and, in certain circumstances, antithrombotic agents, statins are among the most effective drugs in reducing the risk of stroke in populations of patients at high vascular risk, as well as reducing the risk of major ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Phytosterols in cardiovascular disease: innocuous dietary components, or accelerators of atherosclerosis?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 301-310. Plant sterols (phytosterols) are a normal component of the diet. Their uptake and elimination is tightly controlled, so that only very low levels are normally found in plasma. However, rare mutations in genes responsible for phytosterol elimination lead ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Ceramide signaling in cancer and stem cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 273-300. Most of the previous work on the sphingolipid ceramide has been devoted to its function as an apoptosis inducer. Recent studies, however, have shown that in stem cells, ceramide has additional nonapoptotic functions. In this article, ceramide signaling ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Results of the ENHANCE study presentedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 233-235.
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Regulation of cellular steroid levels with special focus on oxysterol and estrogen metabolismEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 337-346. Steroids play essential roles in a number of physiological systems. However, disturbed functions or abnormal levels of steroids can result in serious health problems. The cellular levels of steroids are regulated by enzymes and other factors that control ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Compartmentalizing oxidative stressEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 229-231.
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

AcknowledgementsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 351-351.
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals

Potential roles for inhibitors of arachidonic acid metabolism in prevention and treatment of breast cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Future Lipidology , June 2008, Vol. 3, No. 3, Pages 265-271. Breast cancer is the second leading cause of female cancer-related deaths between the ages of 40 and 50 years in industrialized nations. The essential fatty acid arachidonic acid is suggested to play an important role in the development of various ...
Source: Future Lipidology - May 19, 2008 Category: Lipidology Tags: article Source Type: journals