Cancer chromosome breakpoints cluster in gene ‐rich genomic regions
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 27, 2018 Category: Cancer & Oncology Authors: Felix Mitelman, Bertil Johansson, Fredrik Mertens, Tommy Schyman, Nils Mandahl Tags: RESEARCH ARTICLE Source Type: research

Transcriptome and cytogenetic profiling analysis of matched in situ/invasive cutaneous squamous cell carcinomas from immunocompetent patients
In conclusion, we identified FOSL1 and BNC1, which could act as tumor drivers, and NEK10, which could function as a tumor suppressor, to be differentially expressed during cSCC development.This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Irene Garc ía‐Díez, Inmaculada Hernández‐Muñoz, Eugenia Hernández‐Ruiz, Lara Nonell, Eulàlia Puigdecanet, Marta Bódalo‐Torruella, Evelyn Andrades, Ramon M Pujol, Agustí Toll Tags: RESEARCH ARTICLE Source Type: research

Preface for GCC Special Issue on non ‐coding RNAs, non‐coding DNAs and genome editing
Genes, Chromosomes and Cancer, Volume 0, Issue ja, -Not available-. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: George A. Calin Tags: BRIEF REPORT Source Type: research

Telomere elongation through hTERT immortalisation leads to chromosome repositioning in control cells and genomic instability in Hutchinson ‐Gilford Progeria syndrome fibroblasts, expressing a novel SUN1 isoform
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Mehmet U. Bikkul, Richard G.A. Faragher, Gemma Worthington, Peter Meinke, Alastair R.W. Kerr, Aakila Sammy, Kumars Riyahi, Daniel Horton, Eric C. Schirmer, Michael Hubank, Ian R. Kill, Rhona M. Anderson, Predrag Slijepcevic, Evgeny Makarov, Tags: RESEARCH ARTICLE Source Type: research

Long non ‐coding RNA expression profiling in cancer: challenges and opportunities
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 21, 2018 Category: Cancer & Oncology Authors: Luc ía Lorenzi, Francisco Avila Cobos, Anneleen Decock, Celine Everaert, Hetty Helsmoortel, Steve Lefever, Karen Verboom, Pieter‐Jan Volders, Frank Speleman, Jo Vandesompele, Pieter Mestdagh Tags: REVIEW ARTICLE Source Type: research

Table of Content Volume 57, Number 12, December 2018
Genes, Chromosomes and Cancer, Volume 57, Issue 12, Page 609-610, December 2018. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 16, 2018 Category: Cancer & Oncology Tags: ISSUE INFORMATION ‐ TOC Source Type: research

Identification and monitoring of atypical PML/RARA fusion transcripts in acute promyelocytic leukemia
We report here the characterization of three APL cases harboring atypicalPML/RARA transcripts, which were not clearly detectable after standard RT ‐PCR amplification. In all three cases, clinical, morphological and immunophenotypic features were consistent with APL. Direct sequencing allowed the identification of atypical breakpoints within thePML andRARA genes. We then designed a patient ‐specific Q‐RT‐PCR for the atypical transcripts, which allowed for specific quantitative evaluation of MRD during follow‐up. Despite the rarity of APL cases with an atypicalPML/RARA fusion, our study indicates that an integrated...
Source: Genes, Chromosomes and Cancer - November 12, 2018 Category: Cancer & Oncology Authors: Licia Iaccarino, Mariadomenica Divona, Tiziana Ottone, Laura Cicconi, Serena Lavorgna, Claudia Ciardi, Valentina Alfonso, Serena Travaglini, Luca Facchini, Giuseppe Cimino, Eros Di Bona, Maria Teresa Voso, Francesco Lo ‐Coco Tags: RESEARCH ARTICLE Source Type: research

The FRA14B common fragile site maps to a region prone to somatic and germline rearrangements within the large GPHN gene
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 8, 2018 Category: Cancer & Oncology Authors: Diana Zheglo, Lena M. Brueckner, Olga Sepman, Elisa M. Wecht, Ekaterina Kuligina, Evgenij Suspitsin, Evgenij Imyanitov, Larissa Savelyeva Tags: RESEARCH ARTICLE Source Type: research

Micronucleus formation in human cancer cells is biased by chromosome size
This article is protected by copyright. All rights reserved. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 8, 2018 Category: Cancer & Oncology Authors: Tilmann Bochtler, Mutlu Kartal ‐Kaess, Martin Granzow, Thomas Hielscher, Marco R. Cosenza, Christel Herold‐Mende, Anna Jauch, Alwin Krämer Tags: BRIEF REPORT Source Type: research

Cinsarc signature as a prognostic marker for clinical outcome in sarcomas and beyond
Genes, Chromosomes and Cancer,Volume 0, Issue ja, -Not available-. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 2, 2018 Category: Cancer & Oncology Authors: Frederic Chibon, Tom Lesluyes, Thibaud Valentin, Sophie Le Guellec Source Type: research

A journey with common fragile sites: from S ‐phase to telophase
Genes, Chromosomes and Cancer,Volume 0, Issue ja, -Not available-. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 2, 2018 Category: Cancer & Oncology Authors: Michelle Debatisse, Filippo Rosselli Source Type: research

Common fragile site instability in normal cells: lessons and perspectives
Genes, Chromosomes and Cancer,Volume 0, Issue ja, -Not available-. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 2, 2018 Category: Cancer & Oncology Authors: Elisa Palumbo, Antonella Russo Source Type: research

Cancer Diagnosis and Immunotherapy in the age of CRISPR
Genes, Chromosomes and Cancer,Volume 0, Issue ja, -Not available-. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 1, 2018 Category: Cancer & Oncology Authors: Peter J. Cook, Andrea Ventura Source Type: research

Immunohistochemical Correlates of Recurrent Genetic Alterations in Sarcomas
Genes, Chromosomes and Cancer,Volume 0, Issue ja, -Not available-. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 1, 2018 Category: Cancer & Oncology Authors: William J. Anderson, Jason L. Hornick Source Type: research

miR ‐155 expression in anti‐tumor immunity: the higher the better?
Genes, Chromosomes and Cancer,Volume 0, Issue ja, -Not available-. (Source: Genes, Chromosomes and Cancer)
Source: Genes, Chromosomes and Cancer - November 1, 2018 Category: Cancer & Oncology Authors: Jean ‐Jacques Michaille, Hamdy Awad, Emily C. Fortman, Alexander A. Efanov, Esmerina Tili Source Type: research