Clinical consequences of poor adherence to lipid-lowering therapy in patients with cardiovascular disease: can we do better?
There is high-quality evidence demonstrating that early initiation of statin use following an acute coronary syndrome (ACS) and persistent use thereafter reduces the risk of major adverse cardiovascular events (MACE) including mortality. However, despite the overwhelming evidence, adherence remains suboptimal and the medications frequently discontinued.1 Here we discuss the data on lipid-lowering therapy among patients with cardiovascular disease and discuss some potential interventions that address the gap. Among those with established atherosclerotic cardiovascular disease (ASCVD), poor statin adherence has been reported...
Source: Heart Asia - September 2, 2019 Category: Cardiology Authors: Klimis, H., Chow, C. K. Tags: Open access Editorial Source Type: research
Statin adherence and persistence on secondary prevention of cardiovascular disease in Taiwan
Conclusions
Good adherence and persistence to statin therapy are significantly associated with lower risk of secondary ASCVD rehospitalisation and in-hospital death. (Source: Heart Asia)
Source: Heart Asia - September 2, 2019 Category: Cardiology Authors: Shau, W.-Y., Lai, C.-L., Huang, S.-T., Chen, S.-T., Li, J. Z., Fung, S., Tse, V. C., Lai, M.-S. Tags: Original research Source Type: research
Association of school hours with outcomes of out-of-hospital cardiac arrest in schoolchildren
Conclusions
School hours are not an independent factor associated with improved outcomes of OHCA in schoolchildren. The time delays in CPR and EMS arrival were independently associated with poor outcomes during school hours on school days. (Source: Heart Asia)
Source: Heart Asia - August 19, 2019 Category: Cardiology Authors: Yamashita, A., Kurosaki, H., Takada, K., Tanaka, Y., Hamada, Y., Ishita, T., Kubo, M., Inaba, H. Tags: Original research Source Type: research
Anaesthesia use in catheter ablation for atrial fibrillation: a systematic review and meta-analysis of observational studies
Conclusion
Apart from an increased likelihood of procedural success, ablation by GA/deep sedation was found to be non-significantly different from the mild/moderate sedation approach in both procedural parameters and outcome measures. (Source: Heart Asia)
Source: Heart Asia - August 14, 2019 Category: Cardiology Authors: Li, K. H. C., Sang, T., Chan, C., Gong, M., Liu, Y., Jesuthasan, A., Li, G., Liu, T., Lam, M. H. S., Wu, W. K., Chan, M. T. V., Liu, F.-z., Chen, C., Ho, J., Xia, Y., Tse, G., On behalf of International Health Informatics Study (IHIS) Network Tags: Original research Source Type: research
Transmitral inflow wave and progression from paroxysmal to permanent atrial fibrillation in Asian people
Conclusion
The A velocity could be useful for predicting progression to permanent atrial fibrillation in Asian people. (Source: Heart Asia)
Source: Heart Asia - June 26, 2019 Category: Cardiology Authors: Nakagawa, T., Hara, H., Yamamoto, M., Matsushita, Y., Hiroi, Y. Tags: Original research Source Type: research
Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria
Conclusions
The WHF echocardiographic criteria enable reproducible categorisation of echocardiograms as definite RHD versus no or borderline RHD and hence it would be a suitable tool for screening and monitoring disease progression. The study highlights the strengths and limitations of the WHF echo criteria and provides a platform for future revisions. (Source: Heart Asia)
Source: Heart Asia - June 24, 2019 Category: Cardiology Authors: Remenyi, B., Carapetis, J., Stirling, J. W., Ferreira, B., Kumar, K., Lawrenson, J., Marijon, E., Mirabel, M., Mocumbi, A. O., Mota, C., Paar, J., Saxena, A., Scheel, J., Viali, S., Vijayalakshmi, I. B., Wheaton, G. R., Zuhlke, L., Sidhu, K., Dimalapang, Tags: Original research Source Type: research
Cardioprotective medication adherence among patients with coronary heart disease in China: a systematic review
In China, poor cardioprotective medication adherence is a key reason for the high mortality rate of coronary heart disease (CHD). The aims of this systematic review are to (1) describe and synthesise factors that influence medication adherence among Chinese people with CHD, (2) evaluate the current status of intervention studies, and (3) discuss directions of future research to improve medication adherence. A comprehensive search using PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase, Scopus, Global Health and PsycINFO was undertaken to describe poor adherence in China. Thirty-three eligible article...
Source: Heart Asia - June 24, 2019 Category: Cardiology Authors: Ni, Z., Dardas, L., Wu, B., Shaw, R. Tags: Review Source Type: research
The influence of frailty under direct oral anticoagulant use in patients with atrial fibrillation
Conclusions
Frailty, female sex, hypoalbuminaemia and malignancy were associated with clinical adverse events in patients with AF who were prescribed DOAC. (Source: Heart Asia)
Source: Heart Asia - June 21, 2019 Category: Cardiology Authors: Yamamoto, T., Yamashita, K., Miyamae, K., Koyama, Y., Izumimoto, M., Kamimura, Y., Hayakawa, S., Mori, K., Yamada, T., Tomita, Y., Murohara, T. Tags: Original research Source Type: research
Severe adverse events following benzathine penicillin G injection for rheumatic heart disease prophylaxis: cardiac compromise more likely than anaphylaxis
Conclusion
These results indicate that anaphylaxis is not a major cause of adverse reactions to BPG. An alternative mechanism for sudden death following BPG administration in people with severe RHD is proposed. (Source: Heart Asia)
Source: Heart Asia - June 20, 2019 Category: Cardiology Authors: Marantelli, S., Hand, R., Carapetis, J., Beaton, A., Wyber, R. Tags: Original research Source Type: research
Effects of heat stroke on surface ECG: a study on clinical outcomes
Conclusion
There was high incidence of atrial arrhythmias in patients with classic heat stroke. A low P-wave voltage (<0.01 mV) in lead II was predictive of adverse in-hospital outcome in this cohort of patients. (Source: Heart Asia)
Source: Heart Asia - June 19, 2019 Category: Cardiology Authors: Paul, A., Alex, R., Jacob, J. R., Yadav, B. Tags: Original research Source Type: research
Safety of performing transoesophageal echocardiography in patients with oesophageal varices
Conclusions
TEE is not a common procedure performed in patients with pre-existing EV. TEE seems to be a safe diagnostic tool for evaluation of heart diseases in this group of patients. (Source: Heart Asia)
Source: Heart Asia - June 12, 2019 Category: Cardiology Authors: Hudhud, D., Allaham, H., Eniezat, M., Enezate, T. Tags: Open access Original research Source Type: research
Cardiovascular outcomes of early versus delayed coronary intervention in low to intermediate-risk patients with STEMI in Thailand: a randomised trial
Conclusions
The delayed coronary intervention (>24 hours) in low to intermediate STEMI after successful therapy with SK did not increase in short and long-term cardiovascular events compared with an early coronary intervention.
Trial registration number
NCT02131103. (Source: Heart Asia)
Source: Heart Asia - June 12, 2019 Category: Cardiology Authors: Chotechuang, Y., Phrommintikul, A., Kuanprasert, S., Muenpa, R., Patumanond, J., Chaichuen, T., Sukonthasarn, A. Tags: Open access Original research Source Type: research
Finger necrosis with eosinophilia and symmetrical occlusion of the peripheral artery
Case presentation
A 59-year-old man with hypertension, dyslipidemia and a current smoking history had presented with bilateral painful finger ulcers (figure 1A). The patient was referred to our hospital for the diagnosis and treatment. On his arrival, his fingers showed the development from ulcer to necrosis during the 3 weeks (figure 1B). Diagnostic angiography at the previous hospital had revealed symmetrical occlusions of the forearm and crural arteries (figure 2). Laboratory blood tests demonstrated an eosinophilia (21 %, 1743 cells/µL) with marked elevation of IgE (4200 mg/dL) as well as inflammatory reaction su...
Source: Heart Asia - June 5, 2019 Category: Cardiology Authors: Nishikawa, R., Hirano, T., Kawarada, O. Tags: Image Challenge Source Type: research
Cornell product is an ECG marker of heart failure with preserved ejection fraction
Conclusion
The Cornell product is an easily applicable ECG marker of HFpEF and predicts poor prognosis by reflecting the severity of diastolic dysfunction and LV hypertrophy. (Source: Heart Asia)
Source: Heart Asia - May 28, 2019 Category: Cardiology Authors: Tan, E. S., Chan, S. P., Xu, C. F., Yap, J., Richards, A. M., Ling, L. H., Sim, D., Jaufeerally, F., Yeo, D., Loh, S. Y., Ong, H. Y., Leong, K. T. G., Ng, T. P., Nyunt, S. Z., Feng, L., Okin, P., Lam, C. S., Lim, T. W. Tags: Original research Source Type: research
Left ventricular vortex formation time in elite athletes: novel predictor of myocardial performance
Conclusion
There was no significant difference between VFT at rest and immediately post-exercise. However, VFT at rest correlated with immediate post-exercise augmented systolic and early diastolic tissue Doppler indicators of myocardial performance in elite athletes. (Source: Heart Asia)
Source: Heart Asia - April 24, 2019 Category: Cardiology Authors: Poh, K. K., Ngiam, N., Wood, M. J. Tags: Original research Source Type: research
