Sinus Rhythm Activation Signature Indicates Reentrant Ventricular Tachycardia Inducibility and Approximate Isthmus Location
Sinus rhythm activation time is useful to assess infarct border zone substrate. (Source: Heart Rhythm)
Source: Heart Rhythm - April 25, 2024 Category: Cardiology Authors: Edward J. Ciaccio, James Coromilas, Deepak S. Saluja, Henry H. Hsia, Nicholas S. Peters, Hirad Yarmohammadi Source Type: research

To the Editor: PVC Response Atrial-Pace triggers more than atrial arrhythmias
Refers to: “PVC response Atrial-Pace,” an algorithm designed for preventing pacemaker-induced tachycardia after premature ventricular contractions, triggers atrial high rate episodes.1 (Source: Heart Rhythm)
Source: Heart Rhythm - April 24, 2024 Category: Cardiology Authors: David Gittess, Ramil Goel Source Type: research

Pulsed Field Ablation for Incessant Scar-Related Ventricular Tachycardia: First U.S. Report
70 y/o woman with a history of ischemic cardiomyopathy with ejection fraction of 20% due to a large healed anteroapical infarction. She had previously undergone three prior endocardial radiofrequency ablations for scar-related ventricular tachycardia (VT) with the most recent procedure at our center 4 months prior to the current hospital presentation. During that procedure, three zones of deceleration were identified, and ablation terminated two VT morphologies along the septal aspect of the scar and the patient was rendered noninducible from multiple sites of stimulation within the left ventricle. (Source: Heart Rhythm)
Source: Heart Rhythm - April 24, 2024 Category: Cardiology Authors: Praneeth Katrapati, J. Peter Weiss, David Baning, Michael Zawaneh, Wilber Su, Roderick Tung Source Type: research

Personalized voltage maps guided by cardiac magnetic resonance in the era of high-density mapping
Voltage mapping could identify the conducting channels potentially responsible for ventricular tachycardia (VT). Standard thresholds (0.5-1.5 mV) were established using bipolar catheters. No thresholds have been analyzed with high density mapping catheters. In addition, channels identified by cardiac magnetic resonance (CMR) has been proven to be related with VT. (Source: Heart Rhythm)
Source: Heart Rhythm - April 24, 2024 Category: Cardiology Authors: Sara V ázquez-Calvo, Paz Garre, Elisenda Ferró, Paula Sánchez-Somonte, Jean-Baptiste Guichard, Pasquale Valerio Falzone, Eduard Guasch, Andreu Porta-Sánchez, José Maria Tolosana, Roger Borras, Elena Arbelo, José T. Ortiz-Pérez, Susana Prats, Rosari Source Type: research

Diversity of ICD-10 coding for sudden arrhythmic death syndrome is likely to create a spurious rise in cases under new ICD-11 nomenclature.
Numerous studies have established that the commonest contemporary finding in young sudden cardiac death is a negative autopsy – so-called ‘sudden arrhythmic death syndrome’ (SADS) (1). However, no specific International Classification of Disease (ICD) ICD-10 code described the entity of SADS. (Source: Heart Rhythm)
Source: Heart Rhythm - April 24, 2024 Category: Cardiology Authors: Elizabeth D. Paratz, Louise Fahy, Dion Stub, Ziad Nehme, Vanessa Connell, Andreas Pflaumer, Andre La Gerche Source Type: research

Predicting Post-Infarct Ventricular Tachycardia by Integrating Cardiac MRI and Advanced Computational Reentrant Pathway Analysis
Implantable cardiac defibrillator (ICD) implantation can protect against sudden cardiac death (SCD) after a myocardial infarction. However, improved risk stratification for device requirement is still needed. (Source: Heart Rhythm)
Source: Heart Rhythm - April 23, 2024 Category: Cardiology Authors: Pranav Bhagirath, Fernando O. Campos, Hassan A. Zaidi, Zhong Chen, Mark Elliott, Justin Gould, Michiel J.B. Kemme, Arthur A.M. Wilde, Marco J.W. G ötte, Pieter Postema, Anton J. Prassl, Aurel Neic, Gernot Plank, Christopher A. Rinaldi, Martin J. Bishop Source Type: research

Underestimated Recurrence Rates after Ablation for Wolff-Parkinson-White Syndrome and Impact on Follow-up Practices
The risk of recurrence after accessory pathway (AP) ablation in patients with Wolff-Parkinson-White (WPW) syndrome ranges between 5-12%.1-3 Given practice variation in duration of follow up after successful AP ablation, data on recurrence risk is largely limited to the first year following catheter ablation2. Cases of late recurrence at our institution prompted us to describe our institutional experience including long-term risk of recurrence of WPW pattern on ECG, accessory pathway characteristics before and after recurrence, and the proportion of recurrence that is symptomatic or asymptomatic to better guide follow-up pr...
Source: Heart Rhythm - April 23, 2024 Category: Cardiology Authors: Brendan J. Burke, Iqbal El Assaad, Wei Liu, Mohamed Kanj, Oussama M. Wazni, Thomas D. Callahan, Bryan Baranowski, Elizabeth V. Saarel, Alison Heilbronner, Peter F. Aziz Source Type: research

Operator and Centre Characteristics, And Choice of Pacing Mode
Single- or dual-chamber devices may be implanted in patients requiring a permanent pacemaker (PPM) with a preserved left ventricular ejection fraction and without permanent atrial fibrillation (AF). Although studies have failed to show a mortality benefit of dual- over single-chamber pacing, dual-chamber pacing is associated with lower risks of AF and pacemaker syndrome. As a result of these data, international guidelines recommend dual-chamber pacing as the default option in patients with AV block (AVB) or sinus node disease (SND) but without permanent AF. (Source: Heart Rhythm)
Source: Heart Rhythm - April 23, 2024 Category: Cardiology Authors: Paul A. Scott, Antonio Cannata, Aminat Shote, Ian J. Wright, Anish N. Bhuva, Matthew J. Lovell, Chris Plummer, Mark de Belder, Mark Dayer, Francis D. Murgatroyd Source Type: research

Evaluating Autonomic Outcomes After Pulmonary Vein Isolation: The Differential Effects of Pulsed-Field and Radiofrequency Energy
The autonomic nervous system (ANS) plays a pivotal role in the onset and maintenance of atrial fibrillation (AF). During thermal ablation, the epicardial ganglionated plexi (GP) can inadvertently be affected, as indicated by a post-ablation increase in heart rate (HR) and decrease of heart rate variability (HRV), potentially impacting post-procedural outcomes. Pulsed ‐field ablation (PFA) offers a safer and potentially more effective alternative, as lesion transmurality is not inversely related to safety as in thermal ablation. (Source: Heart Rhythm)
Source: Heart Rhythm - April 23, 2024 Category: Cardiology Authors: Chiara Valeriano, Dimitri Buytaert, Lucio Addeo, Koen De Schouwer, Peter Geelen, Tom De Potter Source Type: research

Prediction of severe ventricular arrhythmias in mitral valve prolapse patients by exercise ECG
Mitral valve prolapse (MVP) is a common condition (prevalence 2-3 %)1, with a good prognosis. However, some MVP patients experience severe ventricular arrhythmias (VA). Identifying patients at risk is challenging and evidence is sparse. The predictive role of exercise testing in MVP has not been investigated. We aimed to explore whether exercise ECG could predict subsequent severe VA in MVP patients. (Source: Heart Rhythm)
Source: Heart Rhythm - April 23, 2024 Category: Cardiology Authors: Christian K. Five, Nina E. Hasselberg, Monica Chivulescu, Christine Rootwelt-Norberg, Margareth P. Ribe, Lars A. Dejgaard, Anna I. Castrini, Eivind W. Aabel, Kristina H. Haugaa Source Type: research

Compliance and Complications in Catecholaminergic Polymorphic Ventricular Tachycardia
Based on this robust study, one can conclude that symptomatic pediatric CPVT patients are at high risk for arrhythmic syncope, SCA and SCD even when receiving medical treatment. Compliance and underdosing with medications play a major role in these risks. LCSD may be underutilized in CPVT. ICDs are protective against these risks but at the cost of a high rate of appropriate and inappropriate shocks and other complications. (Source: Heart Rhythm)
Source: Heart Rhythm - April 22, 2024 Category: Cardiology Authors: Shankar Baskar, Charles I. Berul Source Type: research

The value of invisible electrocardiography
Two or three decades ago, many considered the standard 12-lead electrocardiograms (ECGs) similarly as theoretical physics was seen at the end of 19th century: of some practical use but dull since everything was known making noticeable advances impossible. Indeed, various medical schools stopped studying and teaching ECGs, believing that only diagnostics by standard equipment was of any value. (Source: Heart Rhythm)
Source: Heart Rhythm - April 18, 2024 Category: Cardiology Authors: Marek Malik Tags: Editorial Commentary Source Type: research

Continuous Peripheral Electrical Nerve Stimulation Improves Cardiac Function via Autonomic Nerve Regulation in MI Rats
Peripheral electrical nerve stimulation (PENS) reportedly improves cardiac function after myocardial ischemia (MI) by rebalancing the cardiac autonomic nervous system. The dynamic and continuous influence of the PENS on autonomic and cardiac functioning based on cardiac self-repair is not well understood. (Source: Heart Rhythm)
Source: Heart Rhythm - April 18, 2024 Category: Cardiology Authors: Hanqing Xi, Xia Li, Ziyi Zhang, Xiang Cui, Bing Zhu, Xianghong Jing, Xinyan Gao Source Type: research

Premature Ventricular Complexes: Assessing Burden Density in a Large National Cohort to Better Define Optimal ECG Monitoring Duration
Premature ventricular contractions (PVCs) burden is a risk factor for heart failure and cardiovascular death in patients with structural heart disease. Long-term ECG monitoring can have a significant impact on PVC burden evaluation by further defining PVC distribution patterns. (Source: Heart Rhythm)
Source: Heart Rhythm - April 17, 2024 Category: Cardiology Authors: Andrew Krumerman, Luigi Di Biase, Edward Gerstenfeld, Timm Dickfeld, Nishant Verma, Leonardo Liberman, Richard Amara, Ardit Kacorri, Lori Crosson, Alan Wilk, Kevin J. Ferrick Source Type: research

Premature Ventricular Contractions: the Incidentalomas of Cardiac Electrophysiology?
An incidentaloma generally has two characteristics. First, it is observed as an unintended consequence of ordering a medical test. Second, the subsequent steps for optimal clinical care remain poorly elucidated. Might there be such a phenomenon relevant to cardiac electrophysiology? Two original research manuscripts in this issue of Heart Rhythm remind us that premature ventricular contractions (PVCs) sometimes represent an incidentaloma and sometimes are the prespecified target of scrutiny.1,2 (Source: Heart Rhythm)
Source: Heart Rhythm - April 17, 2024 Category: Cardiology Authors: Krishna Pundi, Gregory M. Marcus Source Type: research