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Serum Levels of Leptin As Marker For Patients At High Risk of Gastric Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Background: Serological screening for gastric cancer (GC) may reduce mortality. However, optimal serum markers for advanced gastric precursor lesions are lacking.Aim: To evaluate in a case[ndash]control study whether serum leptin levels correlate with intestinal metaplasia (IM) and can serve as a tool to identify patients at high risk for GC.Materials and Methods: Cases were patients with a previous diagnosis of IM or dysplasia, controls were patients without such a diagnosis. All patients underwent endoscopy. Fasting serum was collected for the measurement of leptin, pepsinogens I/II, gastrin, and Helicobacter pylori. Rec...
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Lisette G. Capelle, Annemarie C. de Vries, Jelle Haringsma, Ewout W. Steyerberg, Caspar W. N. Looman, Nicole M. A. Nagtzaam, Herman van Dekken, Frank ter Borg, Richard A. de Vries, Ernst J. Kuipers Tags: ORIGINAL ARTICLES Source Type: journals

Modulation of Activation-Induced Cytidine Deaminase by Curcumin in Helicobacter pylori-Infected Gastric Epithelial Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Nonbactericidal concentrations of curcumin downregulated H. pylori-induced AID expression in gastric epithelial cells, probably via the inhibition of NF-[kappa]B pathway. Hence, curcumin can be considered as a potential chemopreventive candidate against H. pylori-related gastric carcinogenesis. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Syed Faisal Haider Zaidi, Takeshi Yamamoto, Alaa Refaat, Kanwal Ahmed, Hiroaki Sakurai, Ikuo Saiki, Takashi Kondo, Khan Usmanghani, Makoto Kadowaki, Toshiro Sugiyama Tags: ORIGINAL ARTICLES Source Type: journals

Host Single Nucleotide Polymorphisms of MMP-9 −1562/TIMP-1 372 Have Gender Differences in the Risk of Gastric Intestinal Metaplasia After Helicobacter pylori Infectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The host MMP-9 [minus]1562/TIMP-1 372 SNPs had gender differences in the risk of IM after H. pylori infection, and could possibly serve as a host factor to identify the risk group harboring gastric precancerous changes after H. pylori infection. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Kuei-Hsiang Hung, Hunt-Wen Hung, Hsiao-Bai Yang, Cheng-Chan Lu, Jiunn-Jong Wu, Bor-Shyang Sheu Tags: ORIGINAL ARTICLES Source Type: journals

LTA 252GG and GA Genotypes are Associated with Diffuse-Type Noncardia Gastric Cancer Risk in the Japanese Populationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The LTA 252 genotype is associated with noncardia gastric cancer of diffuse type in Japan and interacted with radiation dose. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Gen Suzuki, Harry Cullings, Saeko Fujiwara, Shinsuke Matsuura, Takeshi Kishi, Waka Ohishi, Masazumi Akahoshi, Tomonori Hayashi, Eiichi Tahara Tags: ORIGINAL ARTICLES Source Type: journals

Bioaccumulation of Amylose-Like Glycans by Helicobacter pyloriemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: This work shows that under specific environmental conditions, H. pylori expresses a phase-variable cell-surface [alpha]-(1[rarr]4)-glucose moiety. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: José A. Ferreira, Cristiana Pires, Marina Paulo, Nuno F. Azevedo, M. Rosário Domingues, Maria João Vieira, Mario A. Monteiro, Manuel A. Coimbra Tags: ORIGINAL ARTICLES Source Type: journals

Reactive Nitrogen Species Mediate DNA Damage in Helicobacter pylori-Infected Gastric Mucosaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Helicobacter pylori infection can induce inflammatory cells infiltration, which evokes DNA damage of gastric epithelial cells through ROS and RNS production. 8-NG might be a more sensitive biomarker than 8-OHdG for H. pylori-induced DNA damage in gastric mucosa. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Masaki Katsurahara, Yoshinao Kobayashi, Motoh Iwasa, Ning Ma, Hiroyuki Inoue, Naoki Fujita, Kyosuke Tanaka, Noriyuki Horiki, Esteban C. Gabazza, Yoshiyuki Takei Tags: ORIGINAL ARTICLES Source Type: journals

Detection of Helicobacter hepaticus in Human Bile Samples of Patients with Biliary Diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Helicobacter hepaticus may closely associate with diseases of the liver and biliary tract in humans. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Toshihide Hamada, Kenji Yokota, Kiyoshi Ayada, Kazuyuki Hirai, Tomoari Kamada, Ken Haruma, Kazuaki Chayama, Keiji Oguma Tags: ORIGINAL ARTICLES Source Type: journals

Cost-Effectiveness of Eradication of Helicobacter pylori in Gastric Cancer Survivors After Endoscopic Resection of Early Gastric Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: In this selective population with very high risk of developing gastric cancer, H. pylori eradication should be considered for reimbursement with priority to prevent subsequent cancer and also reduce health care cost. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Dong Wook Shin, Young Ho Yun, Il Ju Choi, Eurah Koh, Sang Min Park Tags: ORIGINAL ARTICLES Source Type: journals

Helicobacter pylori Multiplex Serologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: With its high-throughput and simultaneous detection abilities, H. pylori multiplex serology appears suited as tool for large seroepidemiologic studies assessing H. pylori prevalence, antibody patterns, and associations with specific diseases. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Angelika Michel, Tim Waterboer, Manfred Kist, Michael Pawlita Tags: ORIGINAL ARTICLES Source Type: journals

The Modified Sequential Treatment Regimen Containing Levofloxacin for Helicobacter pylori Eradication in Turkeyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Sequential therapy using "rabeprazole and amoxicillin 7 days followed by rabeprazole, metronidazole and levofloxacin for 7 days" is a new regimen with acceptable eradication rates in naïve patients in Turkey. Further modifications in the dose or duration of this new sequential therapy might increase its effectiveness as both first and second line treatment. (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Ahmet Aydin, Nevin Oruc, Ilker Turan, Omer Ozutemiz, Muge Tuncyurek, Ahmet Musoglu Tags: ORIGINAL ARTICLES Source Type: journals

Validation of Diagnostic Tests for Helicobacter pylori with Regard to Grade of Atrophic Gastritis and/or Intestinal Metaplasiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Any one of biopsy-based tests or serology was found to be excellent for identifying current H. pylori infection among individuals without AG or IM and/or younger patients ( (Source: Helicobacter)
Source: Helicobacter - November 4, 2009 Category: Gastroenterology Authors: Cheol Min Shin, Nayoung Kim, Hye Seung Lee, Hee Eun Lee, Sang Hyub Lee, Young Soo Park, Jin Hyuk Hwang, Jin-Wook Kim, Sook-Hyang Jeong, Dong Ho Lee, Hyun Chae Jung, In Sung Song Tags: ORIGINAL ARTICLES Source Type: journals

Clarithromycin–Amoxycillin-Containing Triple Therapy: A Valid Empirical First-Line Treatment for Helicobacter pylori Eradication in Hong Kong?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The standard 7-day clarithromycin-containing triple therapy is still valid as the most effective empirical first-line eradication therapy for H. pylori infection in Hong Kong, as prevalence of primary resistance of H. pylori to amoxycillin and clarithromycin remains low. Patients who failed their empirical first-line eradication therapy should undergo H. pylori susceptibility testing to guide further treatment. (Source: Helicobacter)
Source: Helicobacter - October 1, 2009 Category: Gastroenterology Authors: Ivan F.N. Hung, Pierre Chan, Sally Leung, Fion S.Y. Chan, Axel Hsu, David But, Wai Kay Seto, Siu Yin Wong, Chi Kuen Chan, Qing Gu, Teresa S.M. Tong, Ting Kin Cheung, Kent Man Chu, Benjamin C.Y. Wong Tags: ORIGINAL ARTICLES Source Type: journals

Moxifloxacin-Containing Triple Therapy as Second-Line Treatment for Helicobacter pylori Infection: Effect of Treatment Duration and Antibiotic Resistance on the Eradication Rateemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The 7-day moxifloxacin-containing triple therapy produced an unacceptably low eradication rate. Increasing the duration of therapy was expected to increase the eradication rate, but the expected increased did not materialize, most likely because of coincident marked increase in the prevalence of resistance to moxifloxacin. Tailored treatment based on antibiotic susceptibility testing might be more effective in the achievement of high eradication rate when rapid antibiotic resistance such as moxifloxacin is occurring. (Source: Helicobacter)
Source: Helicobacter - September 10, 2009 Category: Gastroenterology Authors: Hyuk Yoon, Nayoung Kim, Byoung Hwan Lee, Tae Jun Hwang, Dong Ho Lee, Young Soo Park, Ryoung Hee Nam, Hyun Chae Jung, In Sung Song Tags: ORIGINAL ARTICLES Source Type: journals

Corrigendumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Tags: CORRIGENDUM Source Type: journals

Helicobacter pylori Infection Significantly Increases Insulin Resistance in the Asymptomatic Japanese Populationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We examined the association between H. pylori infection and insulin resistance in a large Japanese population.Materials and Methods: Fifteen hundred ninety-eight consecutive asymptomatic subjects that underwent a complete medical survey in our institute between May 2007 and July 2008 were recruited. Cases under medication for hypertension, hyperlipidemia, diabetes mellitus, hyperuricemia, or cardiovascular diseases were excluded from the study. Cases suffering from chronic renal or liver failure were also excluded. The homeostasis model assessment of insulin resistance (HOMA-IR) score was used to quantitatively estimate in...
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Toshiaki Gunji, Nobuyuki Matsuhashi, Hajime Sato, Kazutoshi Fujibayashi, Mitsue Okumura, Noriko Sasabe, Akio Urabe Tags: ORIGINAL ARTICLES Source Type: journals

Evaluation of a New Tumor Necrosis Factor-α-Inducing Membrane Protein of Helicobacter pylori as a Prophylactic Vaccine Antigenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Vaccinations with Tip[alpha] and del-Tip[alpha] were effective against H. pylori infection. The inhibition of H. pylori colonization is associated mainly with Th1 cell-mediated immunity. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Kunimitsu Inoue, Seiji Shiota, Kentaro Yamada, Kazuyo Gotoh, Masami Suganuma, Toshio Fujioka, Kamruddin Ahmed, Hidekatsu Iha, Akira Nishizono Tags: ORIGINAL ARTICLES Source Type: journals

Helicobacter pylori Infection and Family History of Gastric Cancer Decrease Expression of FHIT Tumor Suppressor Gene in Gastric Mucosa of Dyspeptic Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The decreased FHIT gene expression associated with hereditary factors and with H. pylori infection, especially with vacA(+)cagA(+)-positive strains, may be related to gastric carcinoma development. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Krystyna Stec-Michalska, Lukasz Peczek, Blazej Michalski, Maria Wisniewska-Jarosinska, Agnieszka Krakowiak, Barbara Nawrot Tags: ORIGINAL ARTICLES Source Type: journals

Genetic Variation in a4GnT in Relation to Helicobacter pylori Serology and Gastric Cancer Riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: a4GnT genetic variation may be relevant to H. pylori infection, but not to gastric cancer risk. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Zongli Zheng, Yanbin Jia, Lifang Hou, Christina Persson, Meredith Yeager, Jolanta Lissowska, Stephen J. Chanock, Martin Blaser, Wong-Ho Chow, Weimin Ye Tags: ORIGINAL ARTICLES Source Type: journals

Interaction of Helicobacter pylori with Genetic Variants in the MDM2 Promoter, is Associated with Gastric Cancer Susceptibility in Chinese Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The MDM2 promoter SNP309 is associated with the presence of gastric cancer in Chinese patients especially those with H. pylori infection. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Xiaoyong Wang, Jing Yang, Bo Ho, Yang Yang, Zuhu Huang, Zhihong Zhang, Guoxin Zhang Tags: ORIGINAL ARTICLES Source Type: journals

A Population-Based Epidemiologic Study of Helicobacter Pylori Infection and its Association with Systemic Inflammationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Our data suggest that infection with H. pylori is associated with increased systemic inflammation. This suggests one potential mechanism to explain the extra-gastrointestinal conditions associated with H. pylori infection. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Louisa Jackson, John Britton, Sarah A. Lewis, Tricia M. McKeever, John Atherton, Donna Fullerton, Andrew W. Fogarty Tags: ORIGINAL ARTICLES Source Type: journals

Meta-Analysis: Lactobacillus Containing Quadruple Therapy Versus Standard Triple First-Line Therapy for Helicobacter pylori Eradicationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Our review suggests that supplementation with Lactobacilli could be effective in increasing eradication rates of anti-H. pylori therapy for first-treated patients. Furthermore, Lactobacilli showed a positive impact on some H. pylori therapy-related side effects. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Jian Zou, Jie Dong, Xiaofeng Yu Tags: ORIGINAL ARTICLES Source Type: journals

Variables Influencing Outcome of Helicobacter pylori Eradication Therapy in South Chinaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The eradication rate with a PPI, metronidazole and amoxicillin triple therapy was unacceptably low in South China. These results suggest that studies of the eradication of H. pylori infection in China must take into account antibiotic resistance as well as patient occupation, gender, and protocol compliance. Gastric cancer and peptic ulcer disease are both important in China making methods to effectively and efficiently eradicate H. pylori a priority. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Wenzhi Cai, Liping Zhou, Wei Ren, Ling Deng, Min Yu Tags: ORIGINAL ARTICLES Source Type: journals

Annual Change of Primary Resistance to Clarithromycin among Helicobacter pylori Isolates from 1996 through 2008 in Japanemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The resistance rate of H. pylori infection to clarithromycin in Japan has increased gradually to approximately 30% from 1996 through 2004, and remained unchanged since 2004. Elderly and females were at high risk of having resistance to clarithromycin. Our results suggested that the level of clarithromycin resistance in Japan has now risen to the point where it should no longer be used as empiric therapy. (Source: Helicobacter)
Source: Helicobacter - September 8, 2009 Category: Gastroenterology Authors: Noriyuki Horiki, Fumio Omata, Masayo Uemura, Shoko Suzuki, Naoki Ishii, Yusuke Iizuka, Katsuyuki Fukuda, Yoshiyuki Fujita, Masaki Katsurahara, Toshiyuki Ito, Gabazza Esteban Cesar, Ichiro Imoto, Yoshiyuki Takei Tags: ORIGINAL ARTICLES Source Type: journals

The Epidemiology of Helicobacter pylori and Public Health Implicationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article presents a review of the literature on the epidemiology and public health implications of Helicobacter pylori infection published from April 2008 through to March 2009. The authors used MeSH terms "Helicobacter infections epidemiology,""Helicobacter infections prevention and control" to search multiple databases (PubMed, Embase, Cochrane, Cochrane Library, EBMR, BIOSIS), and independently searched PubMed using the term "Helicobacter" with "Epidemiology,""Transmission,""Prevalence" or "Environment." Articles without topical relevance were excluded. Two additional papers known to the authors were added. The iden...
Source: Helicobacter - August 25, 2009 Category: Gastroenterology Authors: Nuno F. Azevedo, Janis Huntington, Karen J. Goodman Tags: The Year in Helicobacter 2009 Source Type: journals

Helicobacter spp. Other Than Helicobacter pyloriemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Non-H. pyloriHelicobacter species (NHPHS) are associated with several important human and animal diseases. In the past year research into this group of bacteria has continued to gain attention, and novel species have been described in new niches owing to improvements in detection methods. Polymerase chain reaction and/or sequencing remain the gold standard for the detection of this genus. New insights into the pathogenesis of the NHPHS in hepatobiliary, gastric, and intestinal diseases were gained. In particular, data revealed interaction between hepatic steatosis and infectious hepatitis in the development of hepatocellul...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Arinze S. Okoli, Armelle Menard, George L. Mendz Tags: REVIEW ARTICLES Source Type: journals

Helicobacters and Extragastric Diseasesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
For two decades, Helicobacter pylori has been considered as the culprit in many extragastric manifestations. However, for several of these supposed associations the hypothesis of an etiological role has not yet been fully investigated. This may be due to a series of factors linked to the epidemiological features of the studies and to the diseases investigated. This review attempts to highlight the main reported associations of H. pylori with extragastric manifestations during the last year. The most convincing data arise in the field of idiopathic thrombocytopenic purpura (ITP) and sideropenic anemia. Long-term follow-up s...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Rinaldo Pellicano, Francesco Franceschi, Giorgio Saracco, Sharmila Fagoonee, Davide Roccarina, Antonio Gasbarrini Tags: REVIEW ARTICLES Source Type: journals

Helicobacter pylori Infection in Pediatricsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This review summarizes the articles published on Helicobacter pylori infection in children between April 2008 and March 2009. Recent evidence highlights the decreasing prevalence trend of H. pylori infection and supports both intrafamilial and extrafamilial transmission. The association with various symptoms is still being debated. Interestingly, H. pylori infection seems inversely associated with allergic diseases. Monoclonal stool antigen tests are widely used and accurate for the diagnosis of H. pylori infection, but less accurate in young children. The new biprobe real-time PCR assay applied to stools showed a poor sen...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Angelika Kindermann, Ana I. Lopes Tags: REVIEW ARTICLES Source Type: journals

Treatment of Helicobacter pylori Infectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article aims to examine current best practice in the field reference to first-line, second-line, rescue and emerging treatment regimens for Helicobater pylori eradication. The recommended first-line treatment in published guidelines in Europe and North American is proton pump inhibitor combined with amoxicillin and clarithromycin being the favoured regimen. Rates of eradication with this regimen however are falling alarmingly due to a combination of antibiotic resistance and poor compliance with therapy. Bismuth based quadruple therapies and levofloxacin based regimes have been shown to be effective second line regime...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Anthony O'Connor, Javier Gisbert, Colm O'Morain Tags: REVIEW ARTICLES Source Type: journals

Helicobacter pylori and Clinical Aspects of Gastric Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In spite of important new insights into the basic mechanisms of gastric carcinogenesis, progress in the management of gastric cancer has been modest. Some modifications in the chemotherapies used for palliation and strategies for downstaging of the disease prior to surgical intervention are noteworthy. The positive experience with endoscopic mucosal resection (EMR) and submucosal dissection (ESD) for treatment of early gastric cancer has been confirmed and extended. The procedure-related morbidity and post-interventional quality of life is clearly favorable compared to open surgical resection in well-selected patients. New...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Jan Bornschein, Theodore Rokkas, Michael Selgrad, Peter Malfertheiner Tags: REVIEW ARTICLES Source Type: journals

Basic Aspects of Gastric Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Gastric cancer is a worldwide health burden, which is still the second most common cause of cancer related deaths with little improvement of long-term survival during the past decades. Understanding the molecular nature of this disease and its precursor lesions has been under intense investigation and our review attempts to highlight recent progress in this field of cancer research. First, host-related genetic susceptibility is dealt with genes involved in inflammation and carcinogen metabolism. Next, role of overexpression of a proinflammatory cytokine (interleukin-1beta) and deletion of a cell-cell adhesion molecule (E-c...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Marta Correia, José Carlos Machado, Ari Ristimäki Tags: REVIEW ARTICLES Source Type: journals

Helicobacter pylori and Non-malignant Diseasesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
It is well known that Helicobacter pylori infection is associated with many nonmalignant disorders such as gastritis, peptic ulcer, gastroesophageal reflux disease (GERD), gastric polyp, nonsteroidal anti-inflammatory drug (NSAID)/aspirin-induced gastric injury, and functional dyspepsia. In 2008, interesting articles on the association of H. pylori infection with these disorders were presented, some of which intended to reveal the mechanisms of inter-individual differences in response to H. pylori infection, and have demonstrated that genetic differences in host and bacterial factors as well as environmental factors accoun...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Takahisa Furuta, Jean-Charles Delchier Tags: REVIEW ARTICLES Source Type: journals

Inflammation, Immunity, and Vaccines for Helicobacter pyloriemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Helicobacter pylori infects almost half of the population worldwide and represents the major cause of gastroduodenal diseases, such as duodenal and gastric ulcer, gastric adenocarcinoma, autoimmune gastritis, and B-cell lymphoma of mucosa-associated lymphoid tissue. Helicobacter pylori induces the activation of a complex and fascinating cytokine and chemokine network in the gastric mucosa. Different bacterial and environmental factors, other concomitant infections, and host genetics may influence the balance between mucosal tolerance and inflammation in the course of H. pylori infection. An inverse association between H. p...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Mario M. D'Elios, Leif P. Andersen Tags: REVIEW ARTICLES Source Type: journals

Pathogenesis of Helicobacter pylori Infectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article will also review the recent novel findings on the interactions of H. pylori with diverse host epithelial signaling pathways and events involved in the initiation of carcinogenesis, including genetic instability and dysregulation of DNA repair. (Source: Helicobacter)
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Ana C Costa, Ceu Figueiredo, Eliette Touati Tags: REVIEW ARTICLES Source Type: journals

Diagnosis of Helicobacter pylori Infectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The articles published this last year in the field of Helicobacter pylori diagnosis reported the development of in vivo histology, small improvements in some invasive methods (urease test, culture, and histology) and new kits for the stool antigen tests. They also contributed to increasing our knowledge, by further exploration into specific conditions for the urea breath test and into the significance of cagA antibodies. The role of serum markers of atrophy was also confirmed. Molecular methods are still being developed for direct genotyping, detection of H. pylori and its clarithromycin resistance, either by polymerase ch...
Source: Helicobacter - August 24, 2009 Category: Gastroenterology Authors: Lurdes Monteiro, Mónica Oleastro, Philippe Lehours, Francis Mégraud Tags: REVIEW ARTICLES Source Type: journals

Presence of High Numbers of Transcriptionally Active Helicobacter pylori in Vomitus from Bangladeshi Patients Suffering from Acute Gastroenteritisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: We conclude that high numbers of transcriptionally active H. pylori are shed in vomitus, which indicates that new infections may be disseminated through vomiting. (Source: Helicobacter)
Source: Helicobacter - July 24, 2009 Category: Gastroenterology Authors: Anders Janzon, Taufiq Bhuiyan, Anna Lundgren, Firdausi Qadri, Ann-Mari Svennerholm, Åsa Sjöling Tags: ORIGINAL ARTICLES Source Type: journals

Author Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: Author Index Source Type: journals

Keyword Indexemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: Keyword Index Source Type: journals

P10 Molecular Genetics and Genomics, Virulence Factors and Pathogenesis IIemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P09 Clinical Trials and Novel Treatments, NSAIDs, COXIBs, ASA, and H. pylori Infectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P08 Microbiology and Drug Resistanceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P07 Gastric Cancer, Preneoplastic and Neoplastic Diseases, Pathology, and Pathophysiologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P06 Molecular Genetics and Genomics, Virulence Factors and Pathogenesis Iemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P05 Other Helicobacters, Hepatobiliary Diseases, Esophageal, and Extradigestive Diseasesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P04 Inflammation, Host response, Immunity, Animal Models, and Vaccinesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P03 Epidemiology and Transmissionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P02 Pediatric Issuesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

P01 Diagnosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

Workshop 8: Genetics and Virulence Factorsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

Workshop 7: Treatmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals

Workshop 6: Gastric Cancer IIemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Helicobacter)
Source: Helicobacter - July 22, 2009 Category: Gastroenterology Tags: ABSTRACTS Source Type: journals