A need for a paradigm shift in focus: From Kt/Vurea to appropriate removal of sodium (the ignored uremic toxin)
This study committed a Type II statistical error rejecting the time of dialysis as an important factor in determining the quality of dialysis. This study also provided the basis for the establishment of the Kt/Vurea index as a measure of dialysis adequacy. This index having been established in a sacrosanct randomized controlled trial (RCT), was readily accepted by the HD community, and led to shorter dialysis, and higher mortality in the United States. Kt/Vurea is a poor measure of dialysis quality because it combines three unrelated variables into a single formula. These variables influence the clinical status of the pati...
Source: Hemodialysis International - November 20, 2018 Category: Hematology Authors: Zbylut J. Twardowski, Madhukar Misra Tags: Review Article Source Type: research

Comparison of biocompatibility in polysulfone dialysis membranes with different sterilization
In this study, the comparison was made between two PSf membranes in order to evaluate the effect of sterilization from the biocompatibility point of view.Methods: We investigated the biocompatibility of the following two dialyzers, that is, APS ‐11SA (Asahi Kasei medical Co., Tokyo, Japan), sterilized by gamma‐ray irradiation, and RENAK PS‐1.0 (Kawasumi laboratories, Tokyo, Japan), sterilized by autoclave. Heparin of 40 units/mL was put in a syringe, and test blood was collected from healthy volunteers. Then, the dialyzer and blood c ircuit were filled with the test blood. Subsequently, the blood was circulated by a ...
Source: Hemodialysis International - November 8, 2018 Category: Hematology Authors: Konomi Togo, Masahito Yamamoto, Takahisa Ono, Motoyuki Imai, Keiichi Akiyama, Kunio Ebine, Akihiro C. Yamashita Tags: Original Article Source Type: research

Scurvy in a hemodialysis patient. Rare or ignored?
We present a case of scurvy in a HD patient that will contribute toward the understanding of vitamin status in HD. We hope it will aid in screening HD patients for vitamin C deficiency and indiv idualizing supplementation of vitamin C. (Source: Hemodialysis International)
Source: Hemodialysis International - November 8, 2018 Category: Hematology Authors: Sarju Panchal, Christine Schneider, Kunal Malhotra Tags: Case Report Source Type: research

Prevention of hemodialysis catheter infections: Ointments, dressings, locks, and catheter hub devices
AbstractTunneled central venous catheters used for the provision of hemodialysis are associated with excess morbidity and mortality. Catheter related exit site and blood stream infections are major risks of their use. Although catheter ‐avoidance is the best strategy to reduce infections and mortality in the hemodialysis population, the use of catheters remains unacceptably high.In this review, the existing clinical practice guidelines for the prevention of hemodialysis catheter associated infections are outlined, and a comprehensive evidenced ‐based summary of interventions is provided. This includes details about the...
Source: Hemodialysis International - November 8, 2018 Category: Hematology Authors: Ladan Golestaneh, Michele H. Mokrzycki Tags: Review Article Source Type: research

Moving beyond small solute clearance: What evidence is there for more permeable dialyzers and haemodiafiltration?
AbstractDialyzers were initially developed for diffusive clearance of uraemic toxins. Diffusion most effectively clears small uncharged solutes from plasma water, such as urea. Sessional urea clearance targets have been shown to be important for short ‐term patient survival, but over the longer term, although low‐flux dialysis can prolong patient survival, accumulation of middle‐sized uraemic toxins, such as β2 microglobulin can lead to disabling arthropathy. Although the introduction of high‐flux dialyzers, designed to increase β2 micr oglobulin clearance, has reduced the prevalence of arthropathy; this has not ...
Source: Hemodialysis International - November 8, 2018 Category: Hematology Authors: Andrew Davenport Tags: Review Article Source Type: research

Successful use of arterio ‐venous graft for hemodialysis in patient with hemophilia
Hemodialysis International, EarlyView. (Source: Hemodialysis International)
Source: Hemodialysis International - November 1, 2018 Category: Hematology Authors: Deepa Amberker, Ting Ting Li, Ritesh Rampure Source Type: research

Removal capacity of different high ‐flux dialyzers during postdilution online hemodiafiltration
Hemodialysis International, EarlyView. (Source: Hemodialysis International)
Source: Hemodialysis International - October 27, 2018 Category: Hematology Authors: Alba Santos Garc ía, Nicolás Macías Carmona, Almudena Vega Martínez, Soraya Abad Estébanez, Tania Linares Grávalos, Inés Aragoncillo Sauco, Ursula Verdalles Guzmán, Nayara Panizo González, Leonidas Cruzado Vega, Juan Manuel López Gómez Source Type: research

Changes to indications for tunneled cuffed catheter use in hemodialysis patients: A single ‐center experience
Hemodialysis International, EarlyView. (Source: Hemodialysis International)
Source: Hemodialysis International - October 26, 2018 Category: Hematology Authors: Takeshi Okamoto, Tsutomu Sakurada, Kenichiro Koitabashi, Yugo Shibagaki Source Type: research

Ethical implications of pursuing hemodialysis in a nonassenting incapacitated patient
Hemodialysis International, EarlyView. (Source: Hemodialysis International)
Source: Hemodialysis International - October 25, 2018 Category: Hematology Authors: Shehryar Khan, Lauren Wake, Kristina Glover, Pedro Bauza, Deepak Prabhakar, Esther Akinyemi Source Type: research

A clinical study comparing the basic performance and blood compatibility characteristics of Nipro ELISIO ‐H®, Gambro Polyflux Revaclear®, and Fresenius Optiflux® dialyzers
Hemodialysis International, EarlyView. (Source: Hemodialysis International)
Source: Hemodialysis International - October 25, 2018 Category: Hematology Authors: Madhukar Misra, Harold Moore Source Type: research

Corrigendum
Hemodialysis International,Volume 22, Issue 4, Page 535-535, October 2018. (Source: Hemodialysis International)
Source: Hemodialysis International - October 22, 2018 Category: Hematology Source Type: research

Corrigendum
Hemodialysis International,Volume 22, Issue 4, Page 534-534, October 2018. (Source: Hemodialysis International)
Source: Hemodialysis International - October 22, 2018 Category: Hematology Source Type: research

Issue information
Hemodialysis International,Volume 22, Issue 4, Page 423-424, October 2018. (Source: Hemodialysis International)
Source: Hemodialysis International - October 22, 2018 Category: Hematology Source Type: research

Choosing a dialyzer: What clinicians need to know
Hemodialysis International, EarlyView. (Source: Hemodialysis International)
Source: Hemodialysis International - October 8, 2018 Category: Hematology Authors: Sabrina Haroon, Andrew Davenport Source Type: research

Tuberculosis in dialysis: Clinical spectrum and outcome from an endemic region
Hemodialysis International, EarlyView. (Source: Hemodialysis International)
Source: Hemodialysis International - October 5, 2018 Category: Hematology Authors: Sanjay Vikrant Source Type: research