Proposed model for the prediction of intrahepatic covalently closed circular DNA level in patients with chronic hepatitis B
ConclusionOur proposed model for the prediction of IH ‐cccDNA level could be helpful in CHB patients. (Source: Hepatology Research)
Source: Hepatology Research - November 26, 2018 Category: Internal Medicine Authors: Kunihiro Hasegawa, Hiroki Nishikawa, Hirayuki Enomoto, Yoshinori Iwata, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Nobuhiro Aizawa, Ryo Takata, Kazunori Yoh, Noriko Ishii, Yukihisa Yuri, Takashi Nishimura, Hiroko Iijima, Etsuro Hatano Tags: Original Article Source Type: research

The efficiency of acoustic radiation force impulse imaging for the staging of graft fibrosis after liver transplantation
ConclusionsARFI helps assess graft LF after LT. The high sensitivity suggested that ARFI may reduce the frequency of liver biopsies by detecting patients who are unlikely to have significant fibrosis after liver transplantation. (Unique trial number: UMIN R000028296) (Source: Hepatology Research)
Source: Hepatology Research - November 24, 2018 Category: Internal Medicine Authors: Kenji Yoshino, Kojiro Taura, Yukihiro Okuda, Yoshinobu Ikeno, Yusuke Uemoto, Takahiro Nishio, Gen Yamamoto, Kazutaka Tanabe, Yukinori Koyama, Satoru Seo, Toshimi Kaido, Hideaki Okajima, Takumi Imai, Shiro Tanaka, Shinji Uemoto Tags: Original Article Source Type: research

Changes in serum levels of leucine ‐rich α2‐glycoprotein predict prognosis in primary biliary cholangitis
ConclusionsChanges in LRG levels after treatment predicted PBC prognosis but were not associated with histological stage. Changes in LRG in addition to the APRI may be a useful tool for clinicians as a noninvasive biomarker. (Source: Hepatology Research)
Source: Hepatology Research - November 24, 2018 Category: Internal Medicine Authors: Manabu Hayashi, Kazumichi Abe, Masashi Fujita, Ken Okai, Atsushi Takahashi, Hiromasa Ohira Tags: Original Article Source Type: research

Inhibition of GSK3 β protects liver against ischemia/reperfusion injury via activating AMPK‐mediated autophagy
ConclusionAutophagy was induced by GSK3 β inhibition through AMPK/mTOR pathway and could substantially ameliorate liver I/R injury. Therefore, our findings strongly renew the therapeutic value of the GSK3β/autophagy axis in the hepatic I/R injury. (Source: Hepatology Research)
Source: Hepatology Research - November 22, 2018 Category: Internal Medicine Authors: Defu Kong, Xiangwei Hua, Tian Qin, Jianjun Zhang, Kang He, Qiang Xia Tags: Original Article Source Type: research

An analysis of 307 cases with drug ‐induced liver injury between 2010 and 2018 in Japan
ConclusionsJapanese DILI patients are somewhat different from those of western countries. The diagnostic scale of the DDW ‐Japan 2004 workshop has been used in Japan. However, there are many issues to improve causality assessment of DILI that we must investigate in future. It is critical to elucidate the mechanisms of drug metabolism and the pathophysiology of liver injury by various drugs to prevent DILI. (Source: Hepatology Research)
Source: Hepatology Research - November 22, 2018 Category: Internal Medicine Authors: Mitsuhiko Aiso, Hajime Takikawa, Keiji Tsuji, Tatehiro Kagawa, Masaaki Watanabe, Atsushi Tanaka, Ken Sato, Shotaro Sakisaka, Yoichi Hiasa, Yoshiyuki Takei, Hiromasa Ohira, Minoru Ayada, Etsuko Hashimoto, Shuichi Kaneko, Yoshiyuki Ueno, Kenj Tags: Original Article Source Type: research

Issue Information
No abstract is available for this article. (Source: Hepatology Research)
Source: Hepatology Research - November 14, 2018 Category: Internal Medicine Tags: Issue Information Source Type: research

Non ‐invasive liver fibrosis assessment correlates with collagen and elastic fiber quantity in patients with hepatitis C
ConclusionLiver fibrosis correlates with fiber quantity through non ‐invasive assessment regardless of fiber type, including elastic fiber. Moreover, MRE is useful for predicting high amounts of elastic fiber. (Source: Hepatology Research)
Source: Hepatology Research - November 12, 2018 Category: Internal Medicine Authors: Yutaka Yasui, Tokiya Abe, Masayuki Kurosaki, Kotaro Matsunaga, Mayu Higuchi, Nobuharu Tamaki, Keiya Watakabe, Mao Okada, Wan Wang, Takao Shimizu, Kenta Takaura, Yohei Masugi, Hiroyuki Nakanishi, Kaoru Tsuchiya, Yuka Takahashi, Jun Itakura, Tags: Original Article Source Type: research

Serosal invasion is a strong prognostic factor for hepatocellular carcinoma after hepatectomy
ConclusionsSerosal invasion was a strong predictor of worse outcomes after hepatectomy for HCC. Patients showing serosal invasion need close postoperative follow ‐up or consideration of adjuvant treatment. (Source: Hepatology Research)
Source: Hepatology Research - November 7, 2018 Category: Internal Medicine Authors: Katsunori Sakamoto, Kohei Ogawa, Taiji Tohyama, Yoshitomo Ueno, Kei Tamura, Hitoshi Inoue, Taro Nakamura, Jota Watanabe, Akihiro Takai, Yasutsugu Takada Tags: Original Article Source Type: research

No ‐touch ablation in hepatocellular carcinoma has the potential to prevent intrasubsegmental recurrence to the same degree as surgical resection
ConclusionThe no ‐touch pincer ablation procedure has the potential to prevent intrasubsegmental recurrence after RFA for patients with HCC to the same degree as partial resection. (Source: Hepatology Research)
Source: Hepatology Research - November 6, 2018 Category: Internal Medicine Authors: Yusuke Kawamura, Kenji Ikeda, Junichi Shindoh, Yuta Kobayashi, Kayoko Kasuya, Shunichiro Fujiyama, Tetsuya Hosaka, Masahiro Kobayashi, Satoshi Saitoh, Hitomi Sezaki, Norio Akuta, Fumitaka Suzuki, Yoshiyuki Suzuki, Yasuji Arase, Masaji Hashim Tags: Original Article Source Type: research

Differential expression of circular RNAs in hepatic tissue in a model of liver fibrosis and functional analysis of theirtarget genes
Hepatology Research,Volume 0, Issue ja, -Not available-. (Source: Hepatology Research)
Source: Hepatology Research - October 31, 2018 Category: Internal Medicine Authors: Yuping Zhou, Xueyou Lv, Hui Qu, Kekai Zhao, Liyun Fu, Linwen Zhu, Guoliang Ye, Junming Guo Source Type: research

Hepatitis C Virus infection could affect the pathogenesis of ischemic heart diseases in northern part of Japan
Hepatology Research,Volume 0, Issue ja, -Not available-. (Source: Hepatology Research)
Source: Hepatology Research - October 30, 2018 Category: Internal Medicine Authors: Ryo Fukuda, Yasuteru Kondo Source Type: research

Epidemiological survey of hemoglobin A1c and liver fibrosis in a general population with non ‐alcoholic fatty liver disease
Hepatology Research,Volume 0, Issue ja, -Not available-. (Source: Hepatology Research)
Source: Hepatology Research - October 27, 2018 Category: Internal Medicine Authors: Kenichi Tanaka, Hirokazu Takahashi, Hideyuki Hyogo, Masafumi Ono, Noriko Oza, Yoichiro Kitajima, Miwa Kawanaka, Kazuaki Chayama, Toshiji Saibara, Keizo Anzai, Yuichiro Eguchi Source Type: research

Combining probiotics and an angiotensin ‐II type 1 receptor blocker has beneficial effects on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis
Hepatology Research,Volume 0, Issue ja, -Not available-. (Source: Hepatology Research)
Source: Hepatology Research - October 26, 2018 Category: Internal Medicine Authors: Yasuhiko Sawada, Hideto Kawaratani, Takuya Kubo, Yukihisa Fujinaga, Masanori Furukawa, Soichiro Saikawa, Shinya Sato, Kenichiro Seki, Hiroaki Takaya, Yasushi Okura, Kosuke Kaji, Naotaka Shimozato, Tsuyoshi Mashitani, Mitsuteru Kitade, Kei Mo Source Type: research

A proposed model for the prediction of intrahepatic covalently closed circular DNA level in patients with chronic hepatitis B
Hepatology Research,Volume 0, Issue ja, -Not available-. (Source: Hepatology Research)
Source: Hepatology Research - October 25, 2018 Category: Internal Medicine Authors: Kunihiro Hasegawa, Hiroki Nishikawa, Hirayuki Enomoto, Yoshinori Iwata, Yoshiyuki Sakai, Naoto Ikeda, Tomoyuki Takashima, Nobuhiro Aizawa, Ryo Takata, Kazunori Yoh, Noriko Ishii, Yukihisa Yuri, Takashi Nishimura, Hiroko Iijima, Etsuro Hatano Source Type: research

Relationship between various hepatic function scores and the formation of esophageal varices in patients with HIV/HCV coinfection due to contaminated blood products for hemophilia
Hepatology Research,Volume 0, Issue ja, -Not available-. (Source: Hepatology Research)
Source: Hepatology Research - October 25, 2018 Category: Internal Medicine Authors: Tomoko Yoshimoto, Susumu Eguchi, Koji Natsuda, Masaaki Hidaka, Tomohiko Adachi, Shinichiro Ono, Takashi Hamada, Yu Huang, Kengo Kanetaka, Mitsuhisa Takatsuki Source Type: research