Human CellThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the latest items in this publication.

Pages: 1 2

99 records returned

Proceedings of The 27th Annual Meeting of the Japan Human Cell Society 22–23 August 2009 Tokyo, JapanEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - October 26, 2009 Category: Cytology Tags: Abstract Source Type: journals

Subject IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - October 26, 2009 Category: Cytology Tags: Subject Index Source Type: journals

Author IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - October 26, 2009 Category: Cytology Tags: Author Index Source Type: journals

Polymorphisms of p53 codon 72 and MDM2 promoter 309 and the risk of endometrial cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Genetic polymorphisms of p53 and its negative regulator murine double minute 2 homolog (MDM2) have been shown to be closely associated with tumorigenesis in a variety of human cancers. In the present study, single nucleotide polymorphism (SNP) at p53 codon 72 and MDM2 promoter 309 was examined for germline DNA samples from 102 endometrial cancer cases and 95 controls using polymerase chain reaction-based fragment analysis. There were no significant differences in the genotype and allele prevalence between control subjects and endometrial cancer patients for p53 codon 72. The GG genotype frequency of MDM2-SNP309 was statist...
Source: Human Cell - October 26, 2009 Category: Cytology Authors: Osamu NUNOBIKI, Masatsugu UEDA, Michiko YAMAMOTO, Eisaku TOJI, Naomi SATO, Shinji IZUMA, Yoshiaki OKAMOTO, Kiyo TORII, Sadamu NODA Tags: Research Articles Source Type: journals

POU6F1 is the transcription factor that might be involved in cell proliferation of clear cell adenocarcinoma of the ovaryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clear cell adenocarcinoma of the ovary often shows resistance to anticancer agents. We investigated new molecules to use when developing molecular-targeting therapy for clear cell adenocarcinoma of the ovary. RMG-I cells without invasive potential and RMG-V cells with invasive potential (derived from clear cell adenocarcinoma of the ovary) were subjected to complementary deoxyribonucleic acid microarray analysis. Caveolin-1, a molecule involved in cellular motility and invasion, showed differing expression between the two cell lines. An RNA interference experiment using the published siRNA for caveolin-1 was carried out. T...
Source: Human Cell - October 26, 2009 Category: Cytology Authors: Norihito YOSHIOKA, Nao SUZUKI, Atsushi UEKAWA, Kazushige KIGUCHI, Bunpei ISHIZUKA Tags: Research Articles Source Type: journals

Characterization and comparison of the properties of sarcoma cell lines in vitro and in vivoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To expand the available tools for investigating human sarcomas, we characterized the primary properties of 22 common, uncommon, and newly characterized sarcoma cell lines representing eight different histological subtypes. Throughout the characterization process we noticed that in vitro markers and assays are poor indicators of tumorigenicity and that generated xenografts often bear little resemblance to the original histopathology. In vitro properties examined included morphology, proliferation rate, cell cycle characteristics, invasiveness, and immunohistochemical expression of p53 and phospho-AKT. In vivo properties exa...
Source: Human Cell - August 1, 2009 Category: Cytology Authors: Joslyn MILLS, Tulio MATOS, Elizabeth CHARYTONOWICZ, Todd HRICIK, Mireia CASTILLO-MARTIN, Fabrizio REMOTTI, Francis Y LEE, Igor MATUSHANSKY Tags: Research Articles Source Type: journals

Establishment and characterization of the NEYS cell line derived from carcinosarcoma of human ovary with special reference to the susceptibility test of anticancer drugsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A cell line designated as NEYS was established from ovarian carcinosarcoma (stage IIIc) of a 56-year-old Japanese woman. The extirpated original tumor was carried in growth medium at 0 °C to the culture room. The primary culture was done on 20 August 2003. The cell line was composed of angular adhesive cells and showed neoplastic and pleomorphic features, such as bizarre aggregation of chromatin granules, an irregular thickening nuclear membrane and multiple large nucleoli. They grew as multi-layered cultures without contact inhibition. The cells proliferated moderately, and population doubling time was about 56 h. The ch...
Source: Human Cell - June 24, 2009 Category: Cytology Authors: Yoshiaki IDE, Taka NAKAHARA, Masanori NASU, Noriko TOMINAGA, Akihiro OHYAMA, Toshiaki TACHIBANA, Makoto YASUDA Source Type: journals

Induced in vitro differentiation of pancreatic-like cells from human amnion-derived fibroblast-like cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is growing evidence that the human amnion contains various types of stem cells. As amniotic tissue is readily available, it has the potential to be an important source of material for regenerative medicine. In the present study, we evaluated the potential of human amnion-derived fibroblast-like (HADFIL) cells to differentiate into pancreatic islet cells. Two HADFIL cell populations, derived from two different neonates, were analyzed. The expression of pancreatic cell-specific genes was examined before and after in vitro induction of cellular differentiation. We found that Pdx-1, Isl-1, Pax-4, and Pax-6 showed signifi...
Source: Human Cell - June 22, 2009 Category: Cytology Authors: Tomoharu TAMAGAWA, Isamu ISHIWATA, Kahei SATO, Yukio NAKAMURA Source Type: journals

Cell cycle, morphology and pluripotency of octaploid embryonic stem cells in comparison with those of tetraploid and diploid cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To examine the alteration of cellular characteristics on ploidy transition of embryonic stem (ES) cells, octaploid cells (8H1 cells) were established from tetraploid H-1 (ES) cells, and compared with tetraploid and diploid H-1 (ES) cells (4H1 and 2H1 cells, respectively). The duration of G1, S, and G2/M phases were essentially the same among 2H1, 4H1, and 8H1 cells, suggesting that cell cycle progression is conserved. The ratio of cell volume of 2H1, 4H1, and 8H1 cells was about 1 : 2 : 4, indicating that these polyploid cells were generated through cell cycle progression without cell division. The morphology of 8H1 cells ...
Source: Human Cell - June 22, 2009 Category: Cytology Authors: Kohzaburo FUJIKAWA-YAMAMOTO, Minoru MIYAGOSHI, Hiroko YAMAGISHI Source Type: journals

Is parainfluenza virus a threatening virus for human cancer cell lines?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Immortalized cell lines, such as human cancer cell lines, are an indispensable experimental resource for many types of biological and medical research. However, unless the cell line has been authenticated prior to use, interpretation of experimental results may be problematic. The potential problems this may cause are illustrated by studies in which authentication of cell lines has not been carried out. For example, immortalized cell lines may unknowingly be infected with viruses that alter their characteristics. In fact, parainfluenza virus type 5 (PIV5) poses a threat to the use of immortalized cell lines in biological a...
Source: Human Cell - June 22, 2009 Category: Cytology Authors: Inaho DANJOH, Hiyori SONE, Nahomi NODA, Emi IIMURA, Mariko NAGAYOSHI, Kaoru SAIJO, Takashi HIROYAMA, Yukio NAKAMURA Source Type: journals

Murine double-minute 2 homolog single nucleotide polymorphism 309 and the risk of gynecologic cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, MDM2-SNP309 was examined in a total of 400 blood samples from 108 normal, 88 cervical, 119 endometrial and 85 ovarian cancer cases using two independent polymerase chain reaction assays for each allele. When the MDM2-SNP309 genotype was classified into two subgroups of TT+TG and GG, the GG genotype was associated with an increased risk for the development of endometrial cancer (odds ratio [OR]= 1.91, 95% confidence interval [CI] = 1.05 to 3.47) compared with the TT+TG genotype (P = 0.0353). The G allele also increased the risk of endometrial cancer (OR = 1.20, 95% CI = 0.83 to 1.74) compared with the T allel...
Source: Human Cell - April 15, 2009 Category: Cytology Authors: Masatsugu Ueda, Michiko Yamamoto, Osamu Nunobiki, Eisaku Toji, Naomi Sato, Shinji Izuma, Yoshiaki Okamoto, Kiyo Torii, Sadamu Noda Tags: Research Articles Source Type: journals

Effects of in vitro culture of mouse fetal gonads on subsequent ovarian development in vivo and oocyte maturation in vitroEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we investigated the effect of in vitro culture of female fetal gonads before transplantation on subsequent in vivo development. The gonads derived from female fetuses 12.5 days postcoitum were organ-cultured for 0, 7 and 14 days, and then were grafted underneath the kidney capsules of severe combined immunodeficient mice and recovered at 21, 14 and 7 days post-transplantation, respectively. The histological analysis of the grafts showed that the in vitro culture of the fetal gonads restricted follicular development to the antral follicle stage post-transplantation. In the grafts cultured for 14 days, particu...
Source: Human Cell - April 15, 2009 Category: Cytology Authors: Hideyuki H MOTOHASHI, Tadashi SANKAI, Koichi NARIAI, Kahei SATO, Hidemi KADA Tags: Research Articles Source Type: journals

Donor age-dependent acceleration of cellular aging by repeated ultraviolet A irradiation of human dermal fibroblasts derived from a single donorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The relationship between cellular aging and aging of entire organisms has been studied extensively. The findings are confusing, however, and no clear relationships have been demonstrated. The conflicting data may be due to individual differences among the donors of the studied cells. It is crucial to identify the changes in cellular properties that are the result of the aging process. Here, we used human dermal fibroblast cell lines established from a single donor at different ages to assess the influence of ultraviolet A (UVA) on cellular aging. These cell lines have the same genetic background and were obtained from a re...
Source: Human Cell - February 23, 2009 Category: Cytology Authors: Eiji NARU, Toshiro OHTA, Ken INOMATA, Akinobu HAYASHI, Kazuhiko KAJI Source Type: journals

Donor age reflects the replicative lifespan of human fibroblasts in cultureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human fibroblasts, which have a finite lifespan in cultures, have been widely used as a model system for cellular aging, and frequently used as one model of human aging. But whether cellular aging contributes to organismal aging has been controversial. To reinvestigate this question, we cultured human fibroblasts from the skin of one individual volunteer collected at different ages. Over a period of 27 years (donor age 36 years to 62 years), we obtained skin cells four times at appropriate intervals, and established eight fibroblast lines. These human fibroblasts have presented evidence for a correlation between donor age ...
Source: Human Cell - February 23, 2009 Category: Cytology Authors: Kazuhiko KAJI, Toshiro OHTA, Nobuyuki HORIE, Eiji NARU, Miho HASEGAWA, Naotoshi KANDA Source Type: journals

Establishment and characterization of a new squamous cell carcinoma cell line, TMUU-08, derived from human bladder cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human squamous cell carcinoma (SCC) of the bladder is a rare malignancy that represents less than 5% of bladder tumors. In contrast to non-bilharzial SCC, bilharzial SCC is a distinct pathological disease that is rarely encountered in Japan. The majority of patients with non-bilharzial SCC present with a poorly differentiated, muscle-invasive tumor with no previous episode of urothelial carcinoma (UC). Even in the absence of distant metastases, the prognosis of patients with non-bilharzial SCC of the bladder remains dismal because patients die of localized recurrence. This is in contrast to UC in which distant metastasis a...
Source: Human Cell - February 12, 2009 Category: Cytology Authors: Choichiro OZU, Hisashi TAKEUCHI, Kazuhito MATSUSHITA, Yutaka HORIGUCHI, Kazunori NAMIKI, Kunihiko YOSHIOKA, Takeshi NAGAI, Masaaki TACHIBANA Tags: Cell Line Source Type: journals

Protective effect of green tea polyphenols against ultraviolet B-induced damage to HaCaT cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Many deleterious effects on the skin have been associated with the ultraviolet B (UVB) portion of the solar spectrum. The role of green tea polyphenols (GTP) in protecting HaCaT cells against the UVB-induced damages was examined. The promotion effect of low level GTP on cell viability was revealed in a dose-dependent manner. High level GTP had a cytotoxic effect. UVB induced destruction of HaCaT cells, including shedding of cell membrane microvilli, degeneration of nucleus and nucleols and changes of mitochondrial size and internal cristae. GTP alleviated the UVB-induced destructive morphological changes in HaCat cells. It...
Source: Human Cell - February 12, 2009 Category: Cytology Authors: Liang-Yu WU, Xin-Qiang ZHENG, Jian-Liang LU, Yue-Rong LIANG Tags: Research Articles Source Type: journals

Tissue injury alters the site of expression of hepatocyte growth factor activator inhibitor type 1 in bronchial epithelial cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hepatocyte growth factor activator inhibitor-1 (HAI-1) is a Kunitz-type transmembrane serine proteinase inhibitor that inhibits trypsin-like serine proteinases, such as hepatocyte growth factor activator, matriptase, hepsin and prostasin. HAI-1 is expressed in polarized epithelial cells, in which HAI-1 is mainly located on the basolateral membrane. In the present study, we analyzed the expression and distribution of HAI-1 in respiratory epithelium. We found that HAI-1 is expressed by the bronchial respiratory epithelium with basal or basolateral localization and also by the alveolar epithelium. Bronchial expression of HAI-...
Source: Human Cell - February 12, 2009 Category: Cytology Authors: Hiroyuki TANAKA, Tsuyoshi FUKUSHIMA, Kenji YORITA, Makiko KAWAGUCHI, Hiroaki KATAOKA Tags: Research Articles Source Type: journals

High frequency of common DNA copy number abnormalities detected by bacterial artificial chromosome array comparative genomic hybridization in 24 breast cancer cell linesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Breast cancer is a widespread disease in Japan and across the world. Breast cancer cells, as well as most other types of cancer cells, have diverse chromosomal aberrations. Clarifying the character of these chromosomal aberrations should contribute to the development of more suitable therapies, along with the predictions of metastasis and prognosis. Twenty-four breast cancer cell lines were analyzed by bacterial artificial chromosome (BAC) array comparative genomic hybridization (CGH). The array slide contained duplicate spots of 4030 BAC clone DNAs covering the entire human genome with 1 Mbp resolution. In all 24 breast c...
Source: Human Cell - February 1, 2009 Category: Cytology Authors: Soichiro SAITO, Keiko MORITA, Takashi HIRANO Tags: Research Articles Source Type: journals

ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Contents Source Type: journals

Poster PresentationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Abstract Source Type: journals

Oral PresentationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Abstract Source Type: journals

Luncheon Seminar 1 & 2Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Abstract Source Type: journals

Symposium3: Battle Front of the Regenerative MedicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Abstract Source Type: journals

Symposium2: Telomere and Cancer Stem CellEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Abstract Source Type: journals

Symposium1: Topics on the Reproductive MedicineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Abstract Source Type: journals

Abstracts of Special Lectures 1–4Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Abstract Source Type: journals

Subject IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Subject Index Source Type: journals

Author IndexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Human Cell)
Source: Human Cell - November 18, 2008 Category: Cytology Tags: Author Index Source Type: journals

Establishment and characterization of HER2-positive cell line derived from pleural effusion of human breast scirrhous carcinomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We have established a cell line derived from a pleural effusion of breast scirrhous carcinoma. This cell line presented immunohistochemically negative for estrogen receptor and slightly positive for progesterone receptor, and positive for c-erbB/HER2/neu. However the original tumor was found to be positive for estrogen receptor and progesterone receptor and slightly positive for c-erbB/HER2/neu expression. Enzyme and electrochemiluminescence immunoassays of tumor markers in the conditioned medium by the cell line revealed they secrete CA15-3, NCC-ST-439 and HER2 protein. We believe the cell line will contribute to the ther...
Source: Human Cell - November 18, 2008 Category: Cytology Authors: Isao TABEI, Shigeki NISHIYAMA, Shigeo YAMASHITA, Hisashi HASHIMOTO, Toshiaki TACHIBANA, Ken UCHIDA, Hiroshi ISHIKAWA Tags: Original Article Source Type: journals

Germline polymorphism of cancer susceptibility genes in gynecologic cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The multifactorial process of carcinogenesis involves mutations in oncogenes, or tumor suppressor genes, as well as the influence of environmental etiological factors. Common DNA polymorphisms in low penetrance genes have emerged as genetic factors that seem to modulate an individual's susceptibility to malignancy. Genetic studies, which lead to a true association, are expected to increase understanding of the pathogenesis of each malignancy and to be a powerful tool for prevention and prognosis in the future. Here, we review the findings of genetic association studies of gene polymorphisms in gynecologic cancer with speci...
Source: Human Cell - November 1, 2008 Category: Cytology Authors: Masatsugu UEDA, Eisaku TOJI, Osamu NUNOBIKI, Shinji IZUMA, Yoshiaki OKAMOTO, Kiyo TORII, Sadamu NODA Tags: Review Article Source Type: journals

Establishment of orthotopic mouse superficial bladder tumor model for studies on intravesical treatmentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Various animal models of bladder tumor have been developed for the preclinical evaluation of therapeutic modalities for the treatment of bladder cancers. The ideal model for the investigation of therapeutic effects of proposed novel intravesical treatments requires the mass of the implanted tumor to be confined to the urothelium of the bladder at least for the initial phase. However, previously reported bladder tumor models are not suitable for the evaluation of intravesical therapies for the treatment of superficial bladder cancer, since the muscle invasive tumors have developed from the beginnings of the experiments. The...
Source: Human Cell - July 31, 2008 Category: Cytology Authors: Yutaka HORIGUCHI, Eiji KIKUCHI, Choichiro OZU, Toru NISHIYAMA, Masafumi OYAMA, Minoru HORINAGA, Kunihiko YOSHIOKA, Masaaki TACHIBANA Tags: Research Articles Source Type: journals

Establishment and characterization of a cell line (IGSK-3) secreting human chorionic gonadotropin, adrenocorticotropic hormone and parathyroid hormone-related protein derived from primary poorly differentiated adenocarcinoma of the stomachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We recently established human chorionic gonadotropin-, adrenocorticotropic hormone- and parathyroid hormone-related protein-secreting cell line derived from primary poorly differentiated adenocarcinoma of the stomach. The cell line was designated as IGSK-3. Inverted-phase contrast microscopy revealed that the IGSK-3 cells consist of two morphological subtypes. One type has visible nucleoli and clear nuclei, but nucleoli and nuclear membrane of the other type are invisible. The population-doubling time was about 43 h. An analysis of conditioned medium by IGSK-3 cells cultured for 4 days revealed the IGSK-3 cells secrete hum...
Source: Human Cell - July 30, 2008 Category: Cytology Authors: Shigeo YAMASHITA, Naoto TAKAHASHI, Hisashi HASHIMOTO, Toshiaki TACHIBANA, Taka NAKAHARA, Akihiro OHYAMA, Katsuhiko YANAGA Tags: Cell Line Source Type: journals

Establishment of a human malignant fibrous mesothelioma cell line and the biological characteristics compared with malignant epithelial mesothelioma cell lineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Two human malignant mesothelioma cell lines, which we designated "epithelial mesothelioma cells" and "fibrous mesothelioma cells", were established from the pleural fluid containing malignant mesothelial cells of a 72-year-old Japanese man. These cell lines were separated by the colonial techniques from the initiation of the primary cultures and grew well without interruption for 12 years. They were characterized as producing hyaluronic acid. These cell lines displayed different biological characteristics, including morphology, heterotransplantability and genetics using with BAC array CGH. The epithelial mesothelioma cells...
Source: Human Cell - July 30, 2008 Category: Cytology Authors: Iwao ISHIWATA, Emiko ISHIWATA, Takashi HIRANO Tags: Research Articles Source Type: journals

Increased levels of a particular phosphatidylcholine species in senescent human dermal fibroblasts in vitroEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Plasma membranes are essential components of living cells, and phospholipids are major components of cellular membranes. Here, we used liquid chromatography/mass spectrometry to investigate changes in the membrane phospholipid content that occur in association with aging. Our results indicate that the levels of a particular species of phosphatidylcholine comprised of stearic acid and arachidonic acid increased with age. To determine the reason for the increased levels of this particular phosphatidylcholine, we examined the effect of highly unsaturated fatty acids, such as arachidonic acid and eicosapentaenoic acid, on cell...
Source: Human Cell - July 30, 2008 Category: Cytology Authors: Eiji NARU, Yasukazu TAKANEZAWA, Misako KOBAYASHI, Yuko MISAKI, Kazuhiko KAJI, Kumi ARAKANE Tags: Research Articles Source Type: journals

Establishment and characterization of a human cell line derived from a uterine papillary serous carcinoma with wild-type p53 functionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Uterine papillary serous carcinoma is an uncommon histologic subtype of endometrial cancer that behaves aggressively and has a poor prognosis. We successfully established a uterine papillary serous carcinoma cell line. The population-doubling time was approximately 16 h. Although loss of p53 function is considered critical for the molecular pathogenesis of uterine papillary serous carcinoma, p53 was not only mutated but functionally active in this cell line. This newly established cell line should be useful for investigating the characteristics of uterine papillary serous carcinoma. (Source: Human Cell)
Source: Human Cell - July 30, 2008 Category: Cytology Authors: Hisashi HASHIMOTO, Atsumi KOJIMA, Tamotsu SUDO, Noriyoshi OHKI, Satoshi YAMAGUCHI, Yoshiki MIKAMI, Masaharu ITO, Ryuichiro NISHIMURA Tags: Research Articles Source Type: journals

Mutational analysis of the BRAF gene in human tumor cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Genes of the RAF family, which mediate cellular responses to growth signals, encode kinases that are regulated by RAS and participate in the RAS, RAF, mitogen/extracellular signal-regulated kinase, extracellular signal-regulated kinase and mitogen-activated protein kinase pathway. As BRAF is a serine/threonine kinase that is commonly activated by somatic point mutation, it may provide possible diagnostic and therapeutic targets in human malignant tumors. We analyzed exon 15 of the BRAF gene for mutations in 58 lung, 12 breast, six kidney, 14 cervical, four endometrial and 10 ovarian carcinoma cell lines by PCR-SSCP and dir...
Source: Human Cell - May 1, 2008 Category: Cytology Authors: Masatsugu UEDA, Eisaku TOJI, Osamu NUNOBIKI, Shinji IZUMA, Yoshiaki OKAMOTO, Kiyo TORII, Sadamu NODA Tags: Research Articles Source Type: journals

Mutational analysis of the BRAF gene in human tumor cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 2, Page 13-17, May 2008. Abstract Genes of the RAF family, which mediate cellular responses to growth signals, encode kinases that are regulated by RAS and participate in the RAS, RAF, mitogen/extracellular signal-regulated kinase, extracellular signal-regulated kinase and ... (Source: Human Cell)
Source: Human Cell - April 4, 2008 Category: Cytology Tags: article Source Type: journals

Induced in vitro differentiation of neural-like cells from human amnion-derived fibroblast-like cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we evaluated the ... (Source: Human Cell)
Source: Human Cell - April 4, 2008 Category: Cytology Tags: article Source Type: journals

G1 arrest and expression of cyclin-dependent kinase inhibitors in tamoxifen-treated MCF-7 human breast cancer cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 2, Page 28-37, May 2008. Abstract Treatment of exponentially growing MCF-7 human breast carcinoma cells with tamoxifen (TAM) inhibits cell growth in a dose-dependent manner. However, the molecular basis for the drug's activity and its relationship to the cell cycle have not yet ... (Source: Human Cell)
Source: Human Cell - April 4, 2008 Category: Cytology Tags: article Source Type: journals

Alteration and preservation of cellular characteristics in long-term culture of tetraploid H-1 (ES) cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 2, Page 18-27, May 2008. Abstract To examine the alteration in cellular characteristics of polyploid ES cells during long-term culturing, tetraploid H-1 (ES) cells were continuously cultured for 180 days. Cellular DNA content of the tetraploid cells decreased and reached a ... (Source: Human Cell)
Source: Human Cell - April 4, 2008 Category: Cytology Tags: article Source Type: journals

Establishment and characterization of a cell line (OMC-9) originating from a human endometrial stromal sarcomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe the establishment and characterization of a new human endometrial ... (Source: Human Cell)
Source: Human Cell - April 4, 2008 Category: Cytology Tags: article Source Type: journals

Serum level of macrophage colony-stimulating factor is increased in prostate cancer patients with bone metastasisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page 1-6, February 2008. Abstract Recent evaluation of human prostate tissues has shown predominantly high expression of the macrophage colony-stimulating factor receptor in prostatic intra-epithelial neoplasia or prostate cancer. However, the expression of its ligand, the ... (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Research Articles Source Type: journals

Abstracts of Special Lectures I & IIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page A1, February 2008. (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Abstracts Source Type: journals

Mitochondrial behavior and localization in reconstituted oocytes derived from germinal vesicle transferEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page 7-11, February 2008. Abstract We investigated the mitochondrial behavior, localization and heteroplasmy in reconstituted oocytes derived from germinal vesicle (GV) transfers. The karyoplast containing the GV nucleus and the ooplast (enucleated oocyte) were prepared from GV ... (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Research Articles Source Type: journals

Abstracts of Poster PresentationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page A16-A21, February 2008. (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Abstracts Source Type: journals

Abstracts of Oral PresentationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page A4-A16, February 2008. (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Abstracts Source Type: journals

Abstract of Luncheon SeminarEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page A4, February 2008. (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Abstracts Source Type: journals

Abstracts of Symposia I–IIIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page A1-A4, February 2008. (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Abstracts Source Type: journals

Erratum: CORRIGENDUMEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 21, Issue 1, Page 12, February 2008. (Source: Human Cell)
Source: Human Cell - January 8, 2008 Category: Cytology Tags: article Corrigendum Source Type: journals

ContentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Human Cell, Volume 20, Issue 4, Page i-iv, November 2007. (Source: Human Cell)
Source: Human Cell - October 18, 2007 Category: Cytology Tags: article Contents Source Type: journals