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IEEE Engineering in Medicine and Biology Magazine - coverEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Table of contentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Dream jobs [from the Editor]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Research funding [President's message]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Communicating your research in lay language [Student's corner]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Multiscale modeling of biomedical, biological, and behavioral systems (part 2)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Image-based biomechanics of collagen-based tissue equivalentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Multiscale modeling of the primary visual cortexEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Computational fluid dynamicsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Variation in the individual airway geometry makes subject-specific models essential for the study of pulmonary air flow and drug delivery. Recent evidence also suggests that early exposure to environmental pollutants has chronic, adverse effects on lung development in children from the age of ten to 18 years [1]. Thus, the capability of predicting air flow and particle deposition in the subjectspecific breathing lungs is highly desirable for understanding the correlation between structure and function and for assessing individual differences in vulnerability to airborne pollutants. Furthermore, it has been demonstrated tha...
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Multiscale modeling of respirationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To distinguish mechanisms of impaired muscle oxygen delivery and oxidative metabolism in response to exercise, we need to evaluate how these factors affect muscle oxygen utilization (UO2m), which represents cellular respiration. During human or animal exercise experiments, direct in vivo measurement of UO2m is not feasible. Instead, pulmonary oxygen uptake (VO2p), which represents external respiration, is measured noninvasively at the mouth as an indirect indicator of metabolic processes that control cellular respiration in the working skeletal muscles [1]. Factors that contribute to the differences between the dynamic res...
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Multiscale modeling in computational biomechanicsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Biomechanics is broadly defined as the scientific discipline that investigates the effects of forces acting on and within biological structures. The realm of biomechanics includes the circulatory and respiratory systems, tissue mechanics and mechanotransduction, and the musculoskeletal system and motor control. As in many other biological phenomena, many spatial scales are crossed by biomechanics research: intracellular, multicellular, and extracellular matrices; and tissue, organ, and multiorgan systems. It is well established that the effect of forces at higher scales influence behavior at lower scales and that lower-sca...
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Error detection and unit conversionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Computer models of physiology are based on physical laws governing chemical reaction kinetics, magnetic fields, hydrodynamics, ion fields, charge transfer, and other phenomena. Equations that instantiate these models represent the relationships among time, mass, distance, force, pressure, chemical concentration, and potential difference. In the Systeme Internationale (SI) system, the seven base units are ampere, candela, kelvin, kilogram, meter, mole, and second. The units may be fundamental, as in SI units, or derived, as with velocity (m/s) or pressure in its varied forms (e.g., 1 mmHg = 1.00000014 torr = 1:33:322 Pa = 1333.22 g cm s
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

What can be patented?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Neural Engineering: EPFL Center for NeuroprostheticsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Helping students recognize the valueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Access for all [point of view]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

In Memory of Dr. Marco Eugenio CabreraEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

CorrectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

GOLD 2009 activities in the EMBS [GOLD]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Accessing the futureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Book Review: Principles and recent advances in medical imaging and image analysis (Dhawan, A.P., Huang, H.K., Kim, D.-S. (editors))Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

The IEEE Engineering in Medicine and Biology Society congratulates The recipients of the 2009 EMBS awardsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

Conference calendarEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - May 21, 2009 Category: Biomedical Engineering Source Type: info

IEEE Engineering in Medicine and Biology Magazine - coverEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Table of contentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

cooperation and competition [From the Editor]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
One of the great aspects of biomedical engineering and life science in general is that all of us who are practitioners for the most part work together. The scientific enterprise is devoted to a better understanding of our world and, through that understanding, improving the quality of life of the world's population. We do this by learning from each other and each of us adding something to what we have learned. We learn by reading, listening to, and exchanging the ideas with our colleagues in the field. Most scientists and engineers not only carry out this type of exchange with colleagues in their own field but also look to...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

EMBC 2009 - Call for PapersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

EMBC 2009Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Feedback relicensure [Letters to the Editor]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Call for Nominations 2009 IEEE EMBS AwardsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

The nuts and bolts of EMBS student chapters! [Student's Corner]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article addresses lessons learned from the formation of an IEEE EMBS student chapter at Kansas State University (KSU) and highlights some of the activities supported by this group, which include research to aid persons with disabilities and hands-on efforts to interest young women in science and engineering.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Call for ADCOM NominationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Multiscale modeling of biomedical, biological, and behavioral systems (Part 1)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Mathematical and computational modeling provide a natural infrastructure for systematically bringing together the wealth of data and knowledge obtained from biological, physiological, and clinical research. Furthermore, the power of this infrastructure is the ability for the model to simulate pathophysiology and predict how, when, and in whom diseases will develop. Historically, the majority of models in biology and physiology are created to understand a particular process or phenomenon by putting together known biological constructs, using modeling to fill in the gaps of the unknown, creating new hypotheses, and redesigni...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Multiscale models of angiogenesisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Vascular disease, cancer, stroke, neurodegeneration, diabetes, inflammation, asthma, obesity, arthritis--the list of conditions that involve angiogenesis reads like main chapters in a book on pathology. Angiogenesis, the growth of capillaries from preexisting vessels, also occurs in normal physiology, in response to exercise or in the process of wound healing.Why and when is angiogenesis prevalent? What controls the process? How can we intelligently control it? These are the key questions driving researchers in fields as diverse as cell biology, oncology, cardiology, neurology, biomathematics, systems biology, and biomedic...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Effect of red blood cells on platelet aggregationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The blood cell that plays a central role in the normal clotting process is the platelet. Blood plateletswere first discovered by Donne in 1842 [1], but 40 years later, Bizzozero [2] recognized the importance of platelet clumping in the blood clotting process. It is now well established that platelet aggregation is not only important for primary hemostasis but when exaggerated can also lead to the formation of occlusive thrombi [3], which form at sites of atherosclerotic plaque rupture, resulting in a heart attack, stroke, or sudden death.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Multiscale modeling of cell mechanics and tissue organizationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nowadays, experimental biology gathers a large number of molecular and genetic data to understand the processes in living systems. Many of these data are evaluated on the level of cells, resulting in a changed phenotype of cells. Tools are required to translate the information on the cellular scale to the whole tissue, wheremultiple interacting cell types are involved. Agent-based modeling allows the investigation of properties emerging from the collective behavior of individual units. A typical agent in biology is a single cell that transports information from the intracellular level to larger scales. Mainly, two scales a...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Multiscale modeling in rodent ventricular myocytesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is a growing body of experimental evidence suggesting that the Ca2+ signaling in ventricular myocytes is characterized by a high gradient near the cell membrane and a more uniform Ca2+ distribution in the cell interior [1]--[7]. An important reason for this phenomenon might be that in these cells the t-tubular system forms a network of extracellular space, extending deep into the cell interior. This allows the electrical signal, that propagates rapidly along the cell membrane, to reach the vicinity of the sarcoplasmic reticulum (SR), where intracellular Ca2+ required for myofilament activation is stored [1], [8]--[11...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Computational multiscale modeling in protein--ligand dockingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In biological systems, the binding of small molecule ligands to proteins is a crucial process for almost every aspect of biochemistry and molecular biology. Enzymes are proteins that function by catalyzing specific biochemical reactions that convert reactants into products. Complex organisms are typically composed of cells in which thousands of enzymes participate in complex and interconnected biochemical pathways. Some enzymes serve as sequential steps in specific pathways (such as energy metabolism), while others function to regulate entire pathways and cellular functions [1]. Small molecule ligands can be designed to bi...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Deriving principles of microbiology by multiscaling laws of molecular physicsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It has long been an objective of the physical sciences to derive principles of biology fromthe laws of physics. At the angstrom scale for processes evolving on timescales of 10-14 s, many systems can be characterized in terms of atomic vibrations and collisions. In contrast, biological systems display dramatic transformations including self-assembly and reorganization from one cell phenotype to another as the microenvironment changes. We have developed a framework for understanding the emergence of living systems from the underlying atomic chaos.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Cardiac tissue engineering using stem cells [Cellular/Tissue Engineering]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The limited clinical success of stem-cell injections for the treatment of myocardial infarction [1], [2] has been mainly attributed to the low retention and survival of injected cells. Alternative methods for improving the efficiency of cell delivery include the following: 1) injection of a mixture of bioactive hydrogels and cells followed by cell-hydrogel polymerization in situ [3] and 2) the epicardial implantation of a tissue-engineered cardiac patch [4]. Although surgically more complex than cell or cell-hydrogel injection, the patch implantation is also expected to yield improved survival of delivered cells, and poten...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Symposium and 3rd Workshop on Wireless & RFID Technology in health Care - 2009Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

HIMSS09 Workshop on Wireless Technology in HealthcareEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Call for Papers - IEEE Transactions on NanoBioscience Special IssueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

The dreaded question. . . [GOLD]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
All good things must come to an end, including a thesis. After years of reading countless journal articles, scouring through textbooks, listening to hours of lectures, attending annual IEEE Engineering in Medicine and Biology Society (EMBS) conferences, meeting numerous clinicians, coding at all hours of the night, and dissecting draft after draft after written draft, there comes a time in every graduate student¿s life when the thesis is ready for the print room. Engineering graduate students around the world spend years of their lives striving toward the goal of a finished thesis product, one which contributes novel idea...
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Jose M. Ferrero (1940--2008)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Career Development in Bioengineering and Biotechnology (G. Madhavean, et al; 2008) [Book Review]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Commercializing Successful Biomedical Technologies: Basic Principles in the Development of Drugs, Diagnostics, and Devices (S.S. Mehta; 2008) [Book Review]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Bakken Museum Social - Sept. 4, 2009Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

IEEE EMBS Corporate Partnership ProgramEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info

Conference Calendar (2009-2011)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: IEEE Engineering in Medicine and Biology - April 17, 2009 Category: Biomedical Engineering Source Type: info