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University College Hospital In London Introduces Treatments Delivering Faster Form Of Radiotherapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Two female brain tumor patients have become the first people in the south of England to be treated using a faster form of radiotherapy that extends more advanced care to more patients. RapidArc technology from Varian Medical Systems (NYSE: VAR) makes it possible to deliver image-guided IMRT (intensity modulated radiotherapy) two to eight times faster than is possible with conventional IMRT. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2009 Category: Consumer Health News Tags: Radiology / Nuclear Medicine Source Type: news

University College Hospital In London Introduces Treatments Delivering Faster Form Of Radiotherapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Two female brain tumor patients have become the first people in the south of England to be treated using a faster form of radiotherapy that extends more advanced care to more patients. RapidArc technology from Varian Medical Systems (NYSE: VAR) makes it possible to deliver image-guided IMRT (intensity modulated radiotherapy) two to eight times faster than is possible with conventional IMRT. (Source: Radiology / Nuclear Medicine News From Medical News Today)
Source: Radiology / Nuclear Medicine News From Medical News Today - November 20, 2009 Category: Radiology Tags: Radiology / Nuclear Medicine Source Type: news

Evaluation of a biplanar diode array dosimeter for quality assurance of step-and-shoot IMRT.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We described and characterized a novel biplanar diode array, and demonstrated its applicability to dosimetric QA of the step-and-shoot IMRT. It is the first commercially available device of its kind specifically designed for measurements at varying gantry angles. The detector consists of a cylindrical PMMA phantom with two orthogonal detector boards. There are a total of 1069 p-type 1 mm wide diode detectors covering the measurement area of 20 x 20 cm2 in each of the measurement planes. The orthogonal detector arrays ensure that the dose modulation information is not lost regardless of the beam incidence angle. For absolut...
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Feygelman V, Forster K, Opp D, Nilsson G Tags: J Appl Clin Med Phys Source Type: journals

Comparing planning time, delivery time and plan quality for IMRT, RapidArc and Tomotherapy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The purpose of this study is to examine plan quality, treatment planning time, estimated treatment delivery time and other dose metrics for 5 and 9 field sliding window IMRT (IMRT5 and IMRT9), single and dual arc Rapid Arc (RA1 and RA2) and Tomotherapy (TOMO). Four cylindrical virtual phantoms were created each with its own distinct set of contours. The contour sets were 2D contours on the axial slice extended in the superior-inferior direction. The prescription dose in all cases was 2 Gy per fraction. IMRT plans were created with 5 or 9 equally spaced beams and RA plans were created with either 1 or 2 complete rotatio...
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Oliver M, Ansbacher W, Beckham WA Tags: J Appl Clin Med Phys Source Type: journals

Direct machine parameter optimization for intensity modulated radiation therapy (IMRT) of oropharyngeal cancer - a planning study.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The purpose of the study was to investigate the potential of direct machine parameter optimization (DMPO) to achieve parotid sparing without compromising target coverage in IMRT of oropharyngeal cancer as compared to fluence modulation with subsequent leaf sequencing (IM) and forward planned 2-step arc therapy (IMAT). IMRT plans were generated for 10 oropharyngeal cancer patients using DMPO and IM. The resulting dose volume histograms (DVH) were evaluated with regard to compliance with the dose volume objectives (DVO) and plan quality. DMPO met the DVO for the targets better than IM but violated the DVO to the parotids...
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Dobler B, Koelbl O, Bogner L, Pohl F Tags: J Appl Clin Med Phys Source Type: journals

Algorithm for correcting optimization convergence errors in Eclipse.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
IMRT plans generated in Eclipse use a Dose Volume Optimizer (DVO) algorithm to evaluate dose for optimization and a more accurate algorithm for a final Volume Dose (VD) calculation, the Analytical Anisotropic Algorithm (AAA). The use of the DVO introduces Optimization Convergence Errors (OCE's) into an IMRT plan. Eclipse has a feature where optimization may be performed on top of an existing base plan. When the base plan is an optimized IMRT plan, a second optimization can compensate for errors in the base plan. Errors in the base plan are demonstrated to originate in the DVO. An IMRT plan containing the same field arr...
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Zacarias AS, Mills MD Tags: J Appl Clin Med Phys Source Type: journals

Effect of Collimator and Couch Angle Change on Breast IMRT Dose Distributions.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objective of this work is to investigate the effects of the collimator and the couch angle change on the dose distribution for breast cancer treatment using intensity modulated tangential photon beams, and thus to determine the clinical acceptable range of the angle change for routine treatment. Ten breast cases treated with intensity modulated tangential photon beams were analyzed in this study. Patient-specific CT data and the RTP files obtained from our home-grown Monte Carlo based breast IMRT treatment planning system were used for IMRT dose re-calculation with collimator or couch angle changes. The isodose distrib...
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Yang J, Ma C, Wang L, Chen L, Li J Tags: J Appl Clin Med Phys Source Type: journals

The effect of interfraction prostate motion on IMRT plans: a dose-volume histogram analysis using a Gaussian error function model.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The Gaussian error function model, containing pairs of error and complementary error functions, was used to carry out cumulative dose-volume histogram (cDVH) analysis on prostate intensity modulated radiation therapy (IMRT) plans with interfraction prostate motion. Cumulative DVHs for clinical target volumes (CTVs) shifted in the anterior-posterior directions based on a 7-beam IMRT plan were calculated and modeled using the Pinnacle3 treatment planning system and a Gaussian error function, respectively. As the parameters in the error function model, namely, a, b and c were related to the shape of the cDVH curve, evalua...
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Chow JC, Jiang R, Markel D Tags: J Appl Clin Med Phys Source Type: journals

A diagnostic tool for basic daily quality assurance of a Tomotherapy Hi*Art machine.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: This tool makes it possible to perform an easy-to-use and fast basic daily quality assurance check featuring an output as well as an energy evaluation. Ideally this tool should offer also the combined dosimetry check of jaw width, couch speed, leaf latency, output, leaf/gantry synchrony and lasers. This will be investigated in the future. PMID: 19918225 [PubMed - in process] (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Van de Vondel I, Tournel K, Verellen D, Duchateau M, Lelie S, Storme G Tags: J Appl Clin Med Phys Source Type: journals

Characterization of cylindrical ionization chambers for patient specific IMRT QA.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Proven conventional dosimetry techniques do not provide accuracy and precision in the measurement of inverse planned intensity modulated radiation therapy (IMRT) fields. Dynamic and step-and-shoot multileaf collimation (DMLC/SMLC) challenge current ionization chamber dosimetry practices. Ionization chamber performance in these fields is evaluated for three cylindrical chambers of varying volumes (PinPoint (PP): 0.015 cm3, IC10: 0.13 cm3, Farmer type NE2571 (FT): 0.69 cm3) in terms of measurement reproducibility, dose measurement linearity, and IMRT dose measurements. Fifty IMRT patient specific quality assurance dose m...
Source: Journal of Applied Clinical Medical Physics - November 20, 2009 Category: Physics Authors: Fraser DJ, Parker W, Seuntjens J Tags: J Appl Clin Med Phys Source Type: journals

Comparison of IMRT planning with two-step and one-step optimization: a strategy for improving therapeutic gain and reducing the integral dose.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The aim of this study was to evaluate the effectiveness and efficiency in inverse IMRT planning of one-step optimization with the step-and-shoot (SS) technique as compared to traditional two-step optimization using the sliding windows (SW) technique. The Pinnacle IMRT TPS allows both one-step and two-step approaches. The same beam setup for five head-and-neck tumor patients and dose-volume constraints were applied for all optimization methods. Two-step plans were produced converting the ideal fluence with or without a smoothing filter into the SW sequence. One-step plans, based on direct machine parameter optimization ...
Source: Physics in Medicine and Biology - November 20, 2009 Category: Physics Authors: Abate A, Pressello MC, Benassi M, Strigari L Tags: Phys Med Biol Source Type: journals

Dose-Rate Effects When Estimating Risks for Second Malignancies: In Regard to Fontenot et al (Int J Radiat Oncol Biol Phys 2009;74:616–622)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To the Editor: In the work by Fontenot et al. , the risk for developing a second malignancy after prostate radiation therapy was estimated for proton therapy and intensity-modulated X-ray therapy (IMRT). The authors conclude that proton therapy can reduce the risk for a second cancer when compared with IMRT. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - November 19, 2009 Category: Radiology Authors: Harald Paganetti, Basit S. Athar, Bryan Bednarz Tags: Letters to the Editor Source Type: journals

[68Ga]-DOTATOC-PET/CT for meningioma IMRT treatment planningemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: DOTATOC-PET/CT information may strongly complement patho-anatomical data from MRI and CT in cases with complex meningioma and is thus helpful for improved target volume delineation especially for skull base manifestations and recurrent disease after surgery. (Source: Radiation Oncology)
Source: Radiation Oncology - November 18, 2009 Category: Cancer & Oncology Authors: Barbara GehlerFrank PaulsenMehmet OksuzTill-Karsten HauserSusanne EschmannRoland BaresChristina PfannenbergMichael BambergPeter BartensteinClaus BelkaUte Ganswindt Source Type: journals

Postoperative Reirradiation for Mucosal Head and Neck Squamous Cell Carcinomas [Original Article]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions  Reirradiation represents the only chance for cure in patients with unresectable disease. After surgery, reirradiation is performed in patients at high risk of locoregional recurrence and may increase acute toxic effects. However, free-flap reconstruction may reduce toxic effects. Functional outcomes have declined since 2000 likely because of the addition of concurrent platinum-based chemotherapy. Future research may define the subpopulation of postoperative patients for whom survival benefits most outweigh reirradiation toxic effects. (Source: Archives of Otolaryngology)
Source: Archives of Otolaryngology - November 16, 2009 Category: ENT & OMF Authors: Iseli, T. A., Iseli, C. E., Rosenthal, E. L., Caudell, J. J., Spencer, S. A., Magnuson, J. S., Smith, A. N., Carroll, W. R. Tags: Oncology, Head & Neck Cancer, Oncology, Other, Otolaryngology/ Head & Neck Surgery, Neoplasms of Head & Neck, Radiation Therapy Original Article Source Type: journals

New technology unveiled at ASTRO 2009email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CHICAGO—Accuray introduced the CyberKnife VSI System. The system is designed to also include conventionally fractionated robotic intensity-modulated radiation therapy. (Source: Cancer Network)
Source: Cancer Network - November 16, 2009 Category: Cancer & Oncology Source Type: info

Intensity-modulated radiotherapy for recurrent and second primary head and neck cancer in previously irradiated territory.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: High-dose IMRT for recurrent and second primary head and neck cancer in previously irradiated territory leads to approximately 20% long-term survival in a non-selected patient population. Identification of patients who would benefit most of curative IMRT is warranted. PMID: 19919885 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 16, 2009 Category: Radiology Authors: Duprez F, Madani I, Bonte K, Boterberg T, Vakaet L, Derie C, De Gersem W, De Neve W Tags: Radiother Oncol Source Type: journals

IMRT delivers high doses to prostate with satisfactory functional outcomesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Prostate cancer patients treated with intensity-modulated radiation therapy experience no significant worsening of urinary, sexual, or bowel function 5 years after treatment, Japanese researchers report. (Source: MedWire News - Prostate Cancer)
Source: MedWire News - Prostate Cancer - November 14, 2009 Category: Cancer & Oncology Source Type: news

Advances In Radiation Therapy Enable Doctors To Improve The Quality Of Treatments For Patients With Head And Neck Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Clinical studies suggest that advanced treatments like intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) are enabling radiation oncologists to enhance post-treatment health-related quality of life for patients with head and neck cancer. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 14, 2009 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Advances In Radiation Therapy Enable Doctors To Improve The Quality Of Treatments For Patients With Head And Neck Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Clinical studies suggest that advanced treatments like intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) are enabling radiation oncologists to enhance post-treatment health-related quality of life for patients with head and neck cancer. In an educational session for radiotherapy professionals, delivered by two noted experts during the annual meeting of the American Society for Radiation Oncology (ASTRO) in Chicago last week, Avraham Eisbruch, M.D. (Source: Cancer / Oncology News From Medical News Today)
Source: Cancer / Oncology News From Medical News Today - November 14, 2009 Category: Cancer & Oncology Tags: Cancer / Oncology Source Type: news

Advances in Radiation Therapy Enable Doctors to Improve the Quality of Treatments for Patients With Head and Neck Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Noted clinical experts detail recent developments at the annual ASTRO meeting in Chicago PALO ALTO, Calif., Nov. 13 (HSMN NewsFeed) -- Clinical studies suggest that advanced treatments like intensity-modulated radiotherapy (IMRT) and image-guided radi... Devices, OncologyVarian Medical Systems, image-guided radiotherapy, IGRT, radiotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 13, 2009 Category: Pharmaceuticals Source Type: news

IMRT delivers high doses to prostate with satisfactory functional outcomesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Prostate cancer patients treated with intensity-modulated radiation therapy experience no significant worsening of urinary, sexual, or bowel function 5 years after treatment, Japanese researchers report. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - November 13, 2009 Category: Cancer & Oncology Source Type: news

Clinical-Dosimetric Analysis of Measures of Dysphagia including Gastrostomy-tube Dependence among Head and Neck Cancer Patients Treated Definitively by Intensity-Modulated Radiotherapy with Concurrent Chemotherapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Our analysis suggests that adhering to the following parameters may decrease the risk of prolonged GT dependence and dysphagia: IPC V65 < 15%, IPC V60 < 40%, IPC Dmean < 55 Gy, and CPI Dmax < 60 Gy. (Source: Radiation Oncology)
Source: Radiation Oncology - November 12, 2009 Category: Cancer & Oncology Authors: Baoqing LiDan LiDerick LauD FarwellQuang LuuDavid RockeKathleen NewmanJean CourquinJames PurdyAllen Chen Source Type: journals

Incidence and Correlates of Radiation Dermatitis in Children and Adolescents Receiving Radiation Therapy for the Treatment of Paediatric Sarcomasemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Aims: To investigate the relationship between the maximum grade of skin toxicity, radiation dose and clinical variables in children receiving treatment for sarcomas involving the bone and soft tissue.Materials and methods: Between January 2003 and July 2006, 82 patients with musculoskeletal tumours on an Institutional Review Board (IRB)-approved prospective study at St. Jude Children's Research Hospital received three-dimensional conformal or intensity-modulated radiation therapy for local tumour control. Radiation dermatitis was graded according to the National Cancer Institute's Common Toxicity Criteria version...
Source: Clinical Oncology - November 9, 2009 Category: Radiology Authors: M.J. Krasin, K.A. Hoth, C. Hua, J.M. Gray, S. Wu, X. Xiong Tags: Original Articles Source Type: journals

A Dosimetric Selectivity Intercomparison of HDR Brachytherapy, IMRT and Helical Tomotherapy in Prostate Cancer Radiotherapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion:   HDR-BT offers better conformality in comparison with HT and IMRT and reduces the volume of healthy tissue receiving a low dose. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00066-009-2009-5Authors Johanne Hermesse, Liège University Hospital Department of Radiation Oncology Liège BelgiumSylvie Biver, Liège University Hospital Department of Radiation Oncology Liège BelgiumNicolas Jansen, Liège University Hospital Department of Radiation Oncology Liège BelgiumEric Lenaerts, Liège University Hospital Department of Medical Physics Liège BelgiumNathalie De Patoul, S...
Source: Strahlentherapie und Onkologie - November 9, 2009 Category: Cancer & Oncology Tags: Strahlentherapie und Onkologie Source Type: journals

Med Tec Inc - CIVCO MTAPSID2932 Type-S Thermoplastic - Class 3 Recallemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CIVCO MTAPSID2932 Type-S Thermoplastic, Disposable nonsterile (48.3 cm) IMRT Style 29 thermoplastic (3.2 mm), Ref. MTAPSID2932, disposable frame mask, 5 per box. The firm name on the label is CIVCO, Orange City, IA. Intended to be used for patient fixation. (Source: Medical Device Recalls since July 07, 2006)
Source: Medical Device Recalls since July 07, 2006 - November 7, 2009 Category: Medical Equipment Source Type: organizations

Evaluation of the impact of dental artefacts on intensity-modulated radiotherapy planning for the head and neck.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Use of an extended CT/density look-up table together with a simple manual bulk density correction reduces the impact of dental artefacts on head and neck IMRT planning to acceptable levels. PMID: 19897267 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 6, 2009 Category: Radiology Authors: Webster GJ, Rowbottom CG, Mackay RI Tags: Radiother Oncol Source Type: journals

Radiotherapy of malignant gliomas: Comparison of volumetric single arc technique (RapidArc), dynamic intensity-modulated technique and 3D conformal technique.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: If PTV is distant to OAR, the use of 3D conformal technique is sufficient. Otherwise an intensity-modulated technique should be used. RapidArc was faster than conventional IMRT and should be preferred if PTV coverage is adequate. PMID: 19897266 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 6, 2009 Category: Radiology Authors: Wagner D, Christiansen H, Wolff H, Vorwerk H Tags: Radiother Oncol Source Type: journals

Mesothelioma Trimodality Therapy Benefits Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In a study recently published in The Annals of Thoracic Surgery, mesothelioma researchers found a trimodality therapeutic approach of chemotherapy, surgery and radiation to be effective in treating malignant pleural mesothelioma. Mesothelioma is a cancer caused almost exclusively by asbestos exposure. A long latency period of 20 to 50 years complicates the diagnostic process and usually leads to a diagnosis at a late stage of cancer development. Because most cases of malignant mesothelioma are diagnosed in a late stage of development, treatment options are often limited to palliative measures intended to improve quality of...
Source: Asbestos and Mesothelioma News - November 5, 2009 Category: Environmental Health Authors: mwhitmer Tags: Asbestos Exposure Mesothelioma Mesothelioma Research Mesothelioma Treatment Malignant Mesothelioma Malignant Pleural Mesothelioma Mesothelioma Cancer Source Type: news

Impact of target volumes and radiation technique on loco-regional control and survival for patients with unilateral cervical lymph node metastases from an unknown primary.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Retrospective comparisons between bilateral and unilateral neck radiotherapies did not show differences in terms of loco-regional control and survival. However, patient's local regional control and survival are significantly improved after 3D-CRT or IMRT. PMID: 19892420 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 4, 2009 Category: Radiology Authors: Ligey A, Gentil J, Créhange G, Montbarbon X, Pommier P, Peignaux K, Truc G, Maingon P Tags: Radiother Oncol Source Type: journals

A treatment planning study comparing helical tomotherapy with intensity-modulated radiotherapy for the treatment of anal cancer.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: HT and IMRT techniques achieved comparable target dose coverage and organ sparing, whereas HT plans were more homogeneous for both men and women. PMID: 19896229 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - November 4, 2009 Category: Radiology Authors: Joseph KJ, Syme A, Small C, Warkentin H, Quon H, Ghosh S, Field C, Pervez N, Tankel K, Patel S, Usmani N, Severin D, Nijjar T, Fallone G, Pedersen J Tags: Radiother Oncol Source Type: journals

Image guided dose escalated prostate radiotherapy: still room to improveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: IGRT to 79.8 Gy results in favourable rates of late toxicity compared with published non-IGRT treated cohorts. Future avenues of investigation for toxicity reduction include IMRT, margin reduction, and dose modulation targeted to sites of disease burden. Further work is required to maximize efficacy beyond that achieved through radiation dose escalation alone. (Source: Radiation Oncology)
Source: Radiation Oncology - November 3, 2009 Category: Cancer & Oncology Authors: Jarad MartinAndrew BayleyRobert BristowPeter ChungMary GospodarowiczCynthia MenardMichael MilosevicTara RosewallPadraig WardeCharles Catton Source Type: journals

Five-year Follow-up of Health-related Quality of Life after Intensity-modulated Radiation Therapy for Prostate Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions IMRT can provide the possibility to deliver a high irradiation dose to the prostate with satisfactory functional outcomes for long-term periods. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - November 2, 2009 Category: Cancer & Oncology Authors: Namiki, S., Ishidoya, S., Ito, A., Tochigi, T., Numata, I., Narazaki, K., Yamada, S., Takai, Y., Arai, Y. Tags: Original Articles Source Type: journals

Anaplastic thyroid cancer: Clinical outcomes with conformal radiotherapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions.Outcomes for anaplastic thyroid cancer treated with 3DRT or IMRT remain equivalent to historical results. Healthy patients with localized disease who tolerate full dose irradiation can potentially enjoy prolonged survival. Biologically targeted radiosensitization merits prioritized investigation. © 2009 Wiley Periodicals, Inc. Head Neck, 2009 (Source: Head and Neck)
Source: Head and Neck - November 2, 2009 Category: ENT & OMF Authors: Aarti Bhatia, Archana Rao, Kie-Kian Ang, Adam S. Garden, William H. Morrison, David I. Rosenthal, Douglas B. Evans, Gary Clayman, Steven I. Sherman, David L. Schwartz Source Type: journals

Critical Appraisal of Volumetric Modulated Arc Therapy in Stereotactic Body Radiation Therapy for Metastases to Abdominal Lymph Nodesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Purpose: A planning study was performed comparing volumetric modulated arcs, RapidArc (RA), fixed beam IMRT (IM), and conformal radiotherapy (CRT) with multiple static fields or short conformal arcs in a series of patients treated with hypofractionated stereotactic body radiation therapy (SBRT) for solitary or oligo-metastases from different tumors to abdominal lymph nodes.Methods and Materials: Fourteen patients were included in the study. Dose prescription was set to 45 Gy (mean dose to clinical target volume [CTV]) in six fractions of 7.5 Gy. Objectives for CTV and planning target volume (PTV) were as follows: Dosemin >...
Source: International Journal of Radiation Oncology * Biology * Physics - November 2, 2009 Category: Radiology Authors: Mario Bignardi, Luca Cozzi, Antonella Fogliata, Paola Lattuada, Pietro Mancosu, Piera Navarria, Gaetano Urso, Sabrina Vigorito, Marta Scorsetti Tags: Physics Contributions Source Type: journals

Accuray Introduces the CyberKnife(R) VSI(TM) Systememail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
New Capabilities Extend CyberKnife Treatment Options to Include Robotic IMRT SUNNYVALE, Calif., Nov. 1 (HSMN NewsFeed) -- Accuray Incorporated (Nasdaq: ARAY ), a global leader in the field of radiosurgery, announced today the introduction of the Cyber... Devices, OncologyAccuray, CyberKnife, CyberKnife VSI, radiosurgery, radiotherapy (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 1, 2009 Category: Pharmaceuticals Source Type: news

Radiation therapy for urologic malignancies in the elderly.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article also reviews the role of radiotherapy in older patients with other urologic malignancies, such as testicular tumor, bladder cancer, renal carcinoma, and penile cancer. PMID: 19879475 [PubMed - in process] (Source: Urologic Oncology)
Source: Urologic Oncology - November 1, 2009 Category: Urology & Nephrology Authors: Sandhu A, Mundt AJ Tags: Urol Oncol Source Type: journals

Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: This study did not find a statistically significant correlation between radiation dose to the PC and observer-assessed dysphagia grade or patient-reported MDADI questionnaire at 1year. PMID: 19883951 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 31, 2009 Category: Radiology Authors: Bhide SA, Gulliford S, Kazi R, El-Hariry I, Newbold K, Harrington KJ, Nutting CM Tags: Radiother Oncol Source Type: journals

Radiation therapy for urologic malignancies in the elderlyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article also reviews the role of radiotherapy in older patients with other urologic malignancies, such as testicular tumor, bladder cancer, renal carcinoma, and penile cancer. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - October 30, 2009 Category: Urology & Nephrology Authors: Ajay Sandhu, Arno J. Mundt Tags: Seminar Articles Source Type: journals

Strategies for Online Organ Motion Correction for Intensity-Modulated Radiotherapy of Prostate Cancer: Prostate, Rectum, and Bladder Dose Effectsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: With online correction of both translations and rotations, a 4-mm margin was sufficient for 15 of 19 patients, whereas the remaining four patients had an underdosed CTV volume (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - October 26, 2009 Category: Radiology Authors: Erik-Jan Rijkhorst, Annemarie Lakeman, Jasper Nijkamp, Josien de Bois, Marcel van Herk, Joos V. Lebesque, Jan-Jakob Sonke Tags: Physics Contributions Source Type: journals

A fast radiotherapy paradigm for anal cancer with volumetric modulated arc therapy (VMAT)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: VMAT provides treatment plans with high conformity and homogeneity equivalent to step-and-shoot-IMRT for this mono-concave treatment volume. Short treatment delivery time and low primary MU are the most important advantages. (Source: Radiation Oncology)
Source: Radiation Oncology - October 25, 2009 Category: Cancer & Oncology Authors: Florian StielerDirk WolffFrank LohrVolker SteilYasser Abo-MadyanFriedlieb LorenzFrederik WenzSabine Mai Source Type: journals

Single crystal chemical vapor deposited diamond detectors for intensity-modulated radiation therapy applicationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report here on first intensity-modulated radiation therapy (IMRT) clinical tests performed at the Gustave Roussy Institute in France using one small (0.117 mm) synthetic single crystal diamond detector (SCDD). We report the comparison between the point doses evaluated with our detector, with a P ... [J. Appl. Phys. 106, 084509 (2009)] published Fri Oct 23, 2009. (Source: Journal of Applied Physics)
Source: Journal of Applied Physics - October 23, 2009 Category: Physics Source Type: journals

Dosimetric study of five-field intensity-modulated radiotherapy compared with conventional three-dimensional conformal radiotherapy for rectal canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  Five-field IMRT-plan is better than 3DCRT-plan in the conformity and the dose homogeneity within target volume and also better in sparing the small bowel and bladder. Content Type Journal ArticleDOI 10.1007/s10330-009-0130-7Authors Bo Yao, General Hospital of Beijing Military Command Department of Radiation Oncology Beijing 100700 ChinaMingmin Zheng, General Hospital of Beijing Military Command Department of Radiation Oncology Beijing 100700 ChinaPing Wang, General Hospital of Beijing Military Command Department of Radiation Oncology Beijing 100700 China Journal The Chinese-German Jou...
Source: The Chinese-German Journal of Clinical Oncology - October 21, 2009 Category: Cancer & Oncology Tags: The Chinese-German Journal of Clinical Oncology Source Type: journals

A generalized inverse planning tool for volumetric-modulated arc therapy.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The recent development in linear accelerator control systems, named volumetric-modulated arc therapy (VMAT), has generated significant interest in arc-based intensity-modulated radiation therapy (IMRT). The VMAT delivery technique features simultaneous changes in dose rate, gantry angle and gantry rotation speed as well as multi-leaf collimator (MLC) leaf positions while radiation is on. In this paper, we describe a generalized VMAT planning tool that is designed to take full advantage of the capabilities of the new linac control systems. The algorithm incorporates all of the MLC delivery constraints such as restrictio...
Source: Physics in Medicine and Biology - October 21, 2009 Category: Physics Authors: Cao D, Afghan MK, Ye J, Chen F, Shepard DM Tags: Phys Med Biol Source Type: journals

A study of middle ear function in the treatment of nasopharyngeal carcinoma with IMRT technique.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: IMRT may have better protected the middle ear function compared with the CRT technique, even with larger fraction sizes than for the conventional CRT technique. PMID: 19853315 [PubMed - as supplied by publisher] (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - October 21, 2009 Category: Radiology Authors: Wang SZ, Li J, Miyamoto CT, Chen F, Zhou LF, Zhang HY, Yang G, Wang WF, Guo M, Ni XC, Wang L Tags: Radiother Oncol Source Type: journals

A dosimetric comparison of four treatment planning methods for high grade gliomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: No single treatment planning method was found to be superior to all others and a personalized approach is advised for planning and treating high-grade glioma patients with radiotherapy. Integral dose did not reflect accurately the dose volume histogram (DVH) of the normal brain and may not be a good indicator of delayed radiation toxicity. (Source: BioMed Central)
Source: BioMed Central - October 20, 2009 Category: Journals (General) Authors: Leor ZachBronwyn StallHolly NingJohn OndosBarbara AroraShankavaram UmaRobert MillerDeborah CitrinKevin Camphausen Source Type: journals

Risk of Fracture After Single Fraction Image-Guided Intensity-Modulated Radiation Therapy to Spinal Metastases [Radiation Oncology]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Vertebral fracture is common after single fraction IG-IMRT for metastatic spine lesions. Lytic disease involving more than 40% of the vertebral body and location at or below T10 confer a high risk of fracture, the presence of which yields significantly poorer clinical outcomes. These results may help clinicians identify high-risk patients who would benefit from prophylactic vertebro- or kyphoplasty. (Source: Journal of Clinical Oncology)
Source: Journal of Clinical Oncology - October 16, 2009 Category: Cancer & Oncology Authors: Rose, Laufer, Boland, Hanover, Bilsky, Yamada, Lis Tags: Risk factors, Radiation Oncology Source Type: journals

Preliminary results of SIB-IMRT in head and neck cancers: Report from a regional cancer center in northern Indiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion&lt;/b&gt; : SIB-IMRT schedules evaluated were found to be safe and effective and are being subjected to further prospective studies. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - October 16, 2009 Category: Cancer & Oncology Authors: Chakraborty Santam, Ghoshal Sushmita, Patil Vijay M, Oinam Arun S, Sharma Suresh C Source Type: journals

Radiotherapy and radiosurgery for benign skull base meningiomasemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Meningiomas located in the region of the base of skull are difficult to access. Complex combined surgical approaches are more likely to achieve complete tumor removal, but frequently at a cost of treatment related high morbidity. Local control following subtotal excision of benign meningiomas can be improved with conventional fractionated external beam radiation therapy with a reported 5-year progression-free survival up to 95%. New radiation techniques, including stereotactic radiosurgery (SRS), fractionated stereotactic radiotherapy (FSRT), and intensity-modulated radiotherapy (IMRT) have been developed as a more accurat...
Source: Radiation Oncology - October 13, 2009 Category: Cancer & Oncology Authors: Giuseppe MinnitiMaurizio AmichettiRiccardo Maurizi Enrici Source Type: journals

Remarks on reporting and recording consistent with the ICRU Reference Doseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The authors advocate reporting the PTV median dose or preferably the mean dose of the central dose plateau PTVx as a potential replacement or successor of the ICRU Reference Dose - both usable for CRT and IMRT. (Source: Radiation Oncology)
Source: Radiation Oncology - October 13, 2009 Category: Cancer & Oncology Authors: Klaus BratengeierMarkus OechsnerMark GaineyMichael Flentje Source Type: journals

Aggressive IMRT and SIB well tolerated by prostate cancer patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Men with intermediate- to high-risk prostate cancer are generally able to tolerate a new and aggressive combination of radiotherapies, findings suggest. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 13, 2009 Category: Cancer & Oncology Source Type: news