Association of neutrophil extracellular trap levels with Raynaud's phenomenon, glomerulonephritis and disease index score in SLE patients from Brazil
This study aimed to access possible associations between serum NETs levels with epidemiological, clinical, and serological data from a well-characterized SLE Brazilian patients' cohort. NET levels were evaluated in one hundred seventy serum samples of patients with Systemic Lupus Erythematosus (SLE) using an Immunoassay. Univariate and multivariate binary logistic regression used clinical patients' data as independent variables. Parametric and non-parametric tests compared log10 base serum NET levels transformed between patients' groups. SLE patients were also dichotomized into "High serum NET levels" and "Low serum NET le...
Source: Immunobiology - April 19, 2024 Category: Allergy & Immunology Authors: Eduardo Delabio Auer Val éria Bumiller-Bini Hoch Emiliano Borges da Silva Yohan Ricci Zonta Luciane Alarc ão Dias-Melicio Thelma Larocca Skare Vanessa F Picceli Iara Jos é Messias-Reason Angelica Beate Winter Boldt Source Type: research
Retraction notice to "In vitro anticholinergic drugs affect CD8+ peripheral blood T-cells apoptosis in COPD" [Immunobiology 217/3 (2012) 345-353]
Immunobiology. 2024 Apr 18:152800. doi: 10.1016/j.imbio.2024.152800. Online ahead of print.NO ABSTRACTPMID:38641460 | DOI:10.1016/j.imbio.2024.152800 (Source: Immunobiology)
Source: Immunobiology - April 19, 2024 Category: Allergy & Immunology Authors: Mirella Profita Loredana Riccobono Angela Marina Montalbano Anna Bonanno Maria Ferraro Giusy Daniela Albano Stefania Gerbino Paola Casarosa Michael Paul Pieper Mark Gjomarkaj Source Type: research
Association of neutrophil extracellular trap levels with Raynaud's phenomenon, glomerulonephritis and disease index score in SLE patients from Brazil
This study aimed to access possible associations between serum NETs levels with epidemiological, clinical, and serological data from a well-characterized SLE Brazilian patients' cohort. NET levels were evaluated in one hundred seventy serum samples of patients with Systemic Lupus Erythematosus (SLE) using an Immunoassay. Univariate and multivariate binary logistic regression used clinical patients' data as independent variables. Parametric and non-parametric tests compared log10 base serum NET levels transformed between patients' groups. SLE patients were also dichotomized into "High serum NET levels" and "Low serum NET le...
Source: Immunobiology - April 19, 2024 Category: Allergy & Immunology Authors: Eduardo Delabio Auer Val éria Bumiller-Bini Hoch Emiliano Borges da Silva Yohan Ricci Zonta Luciane Alarc ão Dias-Melicio Thelma Larocca Skare Vanessa F Picceli Iara Jos é Messias-Reason Angelica Beate Winter Boldt Source Type: research
Retraction notice to "In vitro anticholinergic drugs affect CD8+ peripheral blood T-cells apoptosis in COPD" [Immunobiology 217/3 (2012) 345-353]
Immunobiology. 2024 Apr 18:152800. doi: 10.1016/j.imbio.2024.152800. Online ahead of print.NO ABSTRACTPMID:38641460 | DOI:10.1016/j.imbio.2024.152800 (Source: Immunobiology)
Source: Immunobiology - April 19, 2024 Category: Allergy & Immunology Authors: Mirella Profita Loredana Riccobono Angela Marina Montalbano Anna Bonanno Maria Ferraro Giusy Daniela Albano Stefania Gerbino Paola Casarosa Michael Paul Pieper Mark Gjomarkaj Source Type: research
LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy
Immunobiology. 2024 Apr 6;229(3):152799. doi: 10.1016/j.imbio.2024.152799. Online ahead of print.ABSTRACTWe hereby intend to further explore and confirm the underlying mechanism of Small nucleolar RNA Host Gene 1 (SNHG1) in osteoarthritis (OA). For in vitro assays, OA was induced in primary chondrocytes with interleukin-1β (IL-1β) treatment; while for in vivo tests, OA model was established in mice using the destabilization of the medial meniscus (DMM) method. Cell viability and apoptosis were assessed with MTT and flow cytometry assays, respectively. Cartilage tissue was stained by Safranin-O/Fast Green Staining. The mR...
Source: Immunobiology - April 18, 2024 Category: Allergy & Immunology Authors: Qiushi Wang Jie Yang Rui Pan Zhengang Zha Source Type: research
LncRNA SNHG1 overexpression alleviates osteoarthritis via activating PI3K/Akt signal pathway and suppressing autophagy
Immunobiology. 2024 Apr 6;229(3):152799. doi: 10.1016/j.imbio.2024.152799. Online ahead of print.ABSTRACTWe hereby intend to further explore and confirm the underlying mechanism of Small nucleolar RNA Host Gene 1 (SNHG1) in osteoarthritis (OA). For in vitro assays, OA was induced in primary chondrocytes with interleukin-1β (IL-1β) treatment; while for in vivo tests, OA model was established in mice using the destabilization of the medial meniscus (DMM) method. Cell viability and apoptosis were assessed with MTT and flow cytometry assays, respectively. Cartilage tissue was stained by Safranin-O/Fast Green Staining. The mR...
Source: Immunobiology - April 18, 2024 Category: Allergy & Immunology Authors: Qiushi Wang Jie Yang Rui Pan Zhengang Zha Source Type: research
Increased co-expression of ICOS and PD-1 predicts poor overall survival in patients with acute myeloid leukemia
CONCLUSION: Increased expression of ICOS predicted poor outcomes, and ICOS/PD-1 was the optimal combination of ICs to predict outcomes in patients with AML, which might be a potential immune biomarker for designing novel AML therapy.PMID:38615511 | DOI:10.1016/j.imbio.2024.152804 (Source: Immunobiology)
Source: Immunobiology - April 14, 2024 Category: Allergy & Immunology Authors: Shiyi Pan Qinghua Cai Yiqiong Wei Haifeng Tang Yuping Zhang Wei Zhou Tingfen Deng Wenjian Mo Shunqing Wang Caixia Wang Cunte Chen Source Type: research
Increased co-expression of ICOS and PD-1 predicts poor overall survival in patients with acute myeloid leukemia
CONCLUSION: Increased expression of ICOS predicted poor outcomes, and ICOS/PD-1 was the optimal combination of ICs to predict outcomes in patients with AML, which might be a potential immune biomarker for designing novel AML therapy.PMID:38615511 | DOI:10.1016/j.imbio.2024.152804 (Source: Immunobiology)
Source: Immunobiology - April 14, 2024 Category: Allergy & Immunology Authors: Shiyi Pan Qinghua Cai Yiqiong Wei Haifeng Tang Yuping Zhang Wei Zhou Tingfen Deng Wenjian Mo Shunqing Wang Caixia Wang Cunte Chen Source Type: research
Increased co-expression of ICOS and PD-1 predicts poor overall survival in patients with acute myeloid leukemia
CONCLUSION: Increased expression of ICOS predicted poor outcomes, and ICOS/PD-1 was the optimal combination of ICs to predict outcomes in patients with AML, which might be a potential immune biomarker for designing novel AML therapy.PMID:38615511 | DOI:10.1016/j.imbio.2024.152804 (Source: Immunobiology)
Source: Immunobiology - April 14, 2024 Category: Allergy & Immunology Authors: Shiyi Pan Qinghua Cai Yiqiong Wei Haifeng Tang Yuping Zhang Wei Zhou Tingfen Deng Wenjian Mo Shunqing Wang Caixia Wang Cunte Chen Source Type: research
Increased co-expression of ICOS and PD-1 predicts poor overall survival in patients with acute myeloid leukemia
CONCLUSION: Increased expression of ICOS predicted poor outcomes, and ICOS/PD-1 was the optimal combination of ICs to predict outcomes in patients with AML, which might be a potential immune biomarker for designing novel AML therapy.PMID:38615511 | DOI:10.1016/j.imbio.2024.152804 (Source: Immunobiology)
Source: Immunobiology - April 14, 2024 Category: Allergy & Immunology Authors: Shiyi Pan Qinghua Cai Yiqiong Wei Haifeng Tang Yuping Zhang Wei Zhou Tingfen Deng Wenjian Mo Shunqing Wang Caixia Wang Cunte Chen Source Type: research
Alterations in the immune landscape characterized by inflammatory activation and immune escape within 12 h after trauma
CONCLUSION: Our research has discovered a novel diagnostic biomarker and unveiled its association with post-traumatic immune alterations. This breakthrough enables accurate and timely diagnosis of early trauma, facilitating the implementation of appropriate healthcare interventions.PMID:38593729 | DOI:10.1016/j.imbio.2024.152801 (Source: Immunobiology)
Source: Immunobiology - April 9, 2024 Category: Allergy & Immunology Authors: Chenghu Song Weici Liu Yu Luo Jiwei Liu Guanyu Jiang Ruixin Wang Zhao He Xiaokun Wang Wenjun Mao Source Type: research
Alterations in the immune landscape characterized by inflammatory activation and immune escape within 12 h after trauma
CONCLUSION: Our research has discovered a novel diagnostic biomarker and unveiled its association with post-traumatic immune alterations. This breakthrough enables accurate and timely diagnosis of early trauma, facilitating the implementation of appropriate healthcare interventions.PMID:38593729 | DOI:10.1016/j.imbio.2024.152801 (Source: Immunobiology)
Source: Immunobiology - April 9, 2024 Category: Allergy & Immunology Authors: Chenghu Song Weici Liu Yu Luo Jiwei Liu Guanyu Jiang Ruixin Wang Zhao He Xiaokun Wang Wenjun Mao Source Type: research
Alterations in the immune landscape characterized by inflammatory activation and immune escape within 12 h after trauma
CONCLUSION: Our research has discovered a novel diagnostic biomarker and unveiled its association with post-traumatic immune alterations. This breakthrough enables accurate and timely diagnosis of early trauma, facilitating the implementation of appropriate healthcare interventions.PMID:38593729 | DOI:10.1016/j.imbio.2024.152801 (Source: Immunobiology)
Source: Immunobiology - April 9, 2024 Category: Allergy & Immunology Authors: Chenghu Song Weici Liu Yu Luo Jiwei Liu Guanyu Jiang Ruixin Wang Zhao He Xiaokun Wang Wenjun Mao Source Type: research
Alterations in the immune landscape characterized by inflammatory activation and immune escape within 12 h after trauma
CONCLUSION: Our research has discovered a novel diagnostic biomarker and unveiled its association with post-traumatic immune alterations. This breakthrough enables accurate and timely diagnosis of early trauma, facilitating the implementation of appropriate healthcare interventions.PMID:38593729 | DOI:10.1016/j.imbio.2024.152801 (Source: Immunobiology)
Source: Immunobiology - April 9, 2024 Category: Allergy & Immunology Authors: Chenghu Song Weici Liu Yu Luo Jiwei Liu Guanyu Jiang Ruixin Wang Zhao He Xiaokun Wang Wenjun Mao Source Type: research
PSMC2 promotes glioma progression by regulating immune microenvironment and PI3K/AKT/mTOR pathway
CONCLUSIONS: PSMC2 was upregulated in glioma and promoted cancer progression by modulating the tumor immune microenvironment, cancer cell biological behavior, immune cell homeostasis, and the PI3K/AKT/mTOR pathway, providing a new option to treat glioma.PMID:38569452 | DOI:10.1016/j.imbio.2024.152802 (Source: Immunobiology)
Source: Immunobiology - April 3, 2024 Category: Allergy & Immunology Authors: Yizheng Wang Shiyang Zhang Zijun Zhao Qianxu Jin Zairan Wang Zihan Song Liqiang Liu Zongmao Zhao Source Type: research
