Infectious Diseases in Obstetrics and GynecologyThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

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Detection of Fastidious Vaginal Bacteria in Women with HIV Infection and Bacterial VaginosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Fastidious bacteria (BVAB 1, 2, and 3) remain specific indicators of BV in HIV-infected women, and BVAB2 may contribute to the elevated vaginal pH that is a hallmark of this syndrome. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - November 12, 2009 Category: OBGYN Source Type: journals

Treatment Interruption after Pregnancy: Effects on Disease Progression and Laboratory FindingsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. While changes in CD4 and HIV RNA levels over one year were similar between women stopping or continuing ART postpartum, higher immune activation among women stopping therapy requires further study. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - November 2, 2009 Category: OBGYN Source Type: journals

Once Daily Valacyclovir for Reducing Viral Shedding in Subjects Newly Diagnosed with Genital HerpesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. In this study, the frequency of total and subclinical HSV-2 shedding was greater than reported in earlier studies involving subjects with a history of symptomatic genital recurrences. Our study is the first to demonstrate a significant reduction in viral shedding with valacyclovir 1 g daily compared to placebo in a population of subjects newly diagnosed with HSV-2 infection. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - August 11, 2009 Category: OBGYN Source Type: journals

Incidence and Risk of Cytomegalovirus Infection during Pregnancy in an Urban Area of Northern ItalyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The fetal consequences of CMV infection make it one of the most serious infections contracted during pregnancy, but the scientific community is divided over the proposed implementation of preventive screening for anti-CMV antibodies. The aim of this study was to assess the incidence and risk of infection during pregnancy in 2817 women who underwent anti-CMV IgG and IgM antibody screening during the period 2005–2007. The prevalence of anti-CMV IgG antibodies was 68.3% (95% CI: 66.6–70.0); the seroconversion rate in the 892 seronegative women was 0.32%; the results of IgG avidity testing revealed an c...
Source: Infectious Diseases in Obstetrics and Gynecology - July 27, 2009 Category: OBGYN Source Type: journals

Malaria at Parturition in Nigeria: Current Status and Delivery OutcomeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. In Nigeria, maternal age <20 years was the most important predisposing factor to malaria at parturition. The main impacts on pregnancy outcome were a twofold increase in rate of maternal anaemia and higher prevalence of LBW. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - July 21, 2009 Category: OBGYN Source Type: journals

Trichomonas vaginalis Infection and Associated Risk Factors in a Socially-Marginalized Female Population in Coastal PeruEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. A moderately high prevalence of trichomonal infection was found among women in our study. Trichomonal infection was associated with unprotected sex and multiple sex partners. Efforts to control the continued spread of trichomonal infection are warranted. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 29, 2009 Category: OBGYN Source Type: journals

Species Distribution and Susceptibility to Azoles of Vaginal Yeasts Isolated ProstitutesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. An indiscriminate use of miconazole, such as that observed among female prostitutes in Costa Rica, results in a reduced susceptibility of vaginal yeasts to miconazole but not to other azoles. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

World Wide Web Resources on Obstetrical and Gynecological InfectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Modern information and communications technology has provided medical students and practitioners around the world with a new, valuable, and easy-to-use way to retrieve potentially useful information. Using previously described by our research group methodology, we generated a list of 50 Internet resources in the field of obstetrical and gynecological infections. We believe that the availability of such a list will help in the education of students and clinicians interested in obstetrical and gynecological infections. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Genital Tract Interleukin-8 but not Interleukin-1β or Interleukin-6 Concentration is Associated with Bacterial Vaginosis and Its Clearance in HIV-Infected and HIV-Uninfected WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Genital tract infections and cytokine perturbations are associated with increased HIV acquisition and transmission. We measured the relationship between bacterial vaginosis (BV) and concentrations of Interleukin-8 (IL-8), Interleukin-1β (IL-1β), and Interleukin-6 (IL-6) in cervicovaginal lavage (CVL) specimens collected longitudinally from 16 HIV-infected and 8 HIV-uninfected high-risk women. CVL samples were analyzed when women presented with BV, and at their next visit, after successful treatment, when BV was cleared. A subset of participants had cytokine levels evaluated at three consecutive clinic visits:...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Phase I Trial of a Lactobacillus crispatus Vaginal Suppository for Prevention of Recurrent Urinary Tract Infection in WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: L. crispatus CTV-05 can be given as a vaginal suppository with minimal sideeffects to healthy women with a history of recurrent UTI. Mild inflammation of the urinary tract was noted in some women. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Safety Study of an Antimicrobial Peptide Lactocin 160, Produced by the Vaginal Lactobacillus rhamnosusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Lactocin 160 showed minimal irritation and has a good potential for intravaginal application. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Cost Comparisons between Home- and Clinic-Based Testing for Sexually Transmitted Diseases in High-Risk Young WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We examined the cost differences between home-based and clinic-based testing and the cost-effectiveness of home testing based on the DAISY study, a randomized controlled trial. Direct and indirect costs were estimated for home and clinic testing, and cost-effectiveness was calculated as cost per additional test performed. In the clinic testing group, direct costs were $49/test and indirect costs (the costs of seeking or receiving care) were $62/test. Home testing cost was $25/test. We found that home testing was cost saving when all testing for all patients was considered. However cost savings were not seen whe...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Staphylococcus aureus and MRSA Colonization Rates among Gravidas Admitted to Labor and Delivery: A Pilot StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Rates of Staphylococcus aureus colonization among gravidas entering labor and delivery are modest and consistent with the general population. MRSA rates among gravidas appear to be reassuringly low in this pilot study. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Human Papillomavirus in Endometrial Adenocarcinomas: Infectious Agent or a Mere “Passenger”?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. It appears that the presence of HPV in the endometrium, as detected by PCR, does not play any role in the initiation or prognosis of endometrial adenocarcinoma. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Provider Knowledge, Attitudes, and Practices regarding Obstetric and Postsurgical Gynecologic Infections Due to Group A Streptococcus and Other Infectious AgentsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Postpartum and postsurgical infections are common. Providing empiric treatment without attaining diagnostic cultures represents a missed opportunity for potential prevention of diseases such as severe GAS infections. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Morbidly Obese Woman Unaware of Pregnancy until Full-Term and Complicated by Intraamniotic Sepsis with PseudomonasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 32-year-old Caucasian woman of body mass index (BMI) 46 presented with urinary symptoms to accident and emergency (A&E). Acute pyelonephritis was the diagnosis. Transabdominal scan revealed a live term fetus. Both the partners were unaware of the ongoing pregnancy until diagnosed. She underwent emergency cesarean under general anaesthesia (GA) for nonreassuring CTG, severe chorioamnionitis, and moderate preecclampsia. A live male baby weighing 4400 grams delivered in poor condition. Placental tissue on culture exhibited scanty growth of pseudomonas aeruginosa. Chorioamnionitis due to pseudomonas is rare, with ...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Tubercular Sinus of Labia Majora: Rare Case ReportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a 50-year-old female patient admitted to Department to Surgery with swelling over left inguinal area with discharging sinus from labia majora to left inguinal crease which was found to be tubercular sinus on histopathology. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Pulmonary Tuberculosis in a Young Pregnant Female: Challenges in Diagnosis and ManagementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. A high index of suspicion is required to recognize the changing face and disease spectrum of tuberculosis and initiate treatment for better outcomes. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

The Relationship between Cocaine Use and Human Papillomavirus Infections in HIV-Seropositive and HIV-Seronegative WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Cocaine use is associated with an increased risk of detection of both prevalent and incident oncogenic HPV infection, as well as an increased risk of HPV-positive SIL over time. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

High Rate of Severe Fetal Outcomes Associated with Maternal Parvovirus B19 Infection in PregnancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. These findings suggest that parvovirus B19 infection in pregnancy follows seasonal and annual trend variation, may produce a lower frequency of maternal symptoms and a higher fetal loss rate than previously reported. Synopsis. Maternal parvovirus B19 infection follows seasonal and annual variation is often asymptomatic and may have higher fetal loss rates than previously reported. Continued surveillance is warranted. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Human Granulocytic Ehrlichiosis Complicating Early PregnancyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Treatment of human granulocytic ehrlichiosis in pregnancy presents unique challenges. Management of pyrexia during pregnancy is limited to external cooling in the setting of thrombocytopenia and elevated aminotransferases. Extensive counseling regarding teratogenic potential of medications allows the patient to weigh the pros and cons of treatment. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Tetracycline Effects on Candida Albicans Virulence FactorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Tetracycline appears to have a small growth enhancing effect and may influence virulence through augmentation of hypha formation, and a modest effect on drug efflux and biofilm formation, although tetracycline did not affect hemolysin. It is not clear if the magnitude of the effect is sufficient to attribute vaginitis following tetracycline treatment to direct action of tetracycline on yeast. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

The Metabolism and Transplacental Transfer of Oseltamivir in the Ex Vivo Human ModelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Oseltamivir phosphate was extensively metabolized in the ex vivo model. Transplacental transfer of the metabolite was incomplete and accumulation was minimal. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Effect of Semen on Vaginal Fluid Cytokines and Secretory Leukocyte Protease InhibitorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: proinflammatory cytokine measurement does not appear to be affected by the presence of semen, but secretory leukocyte protease inhibitor is significantly higher when semen is present. Detection of semen by acid phosphatase was associated with higher vaginal SLPI concentrations, however, the presence of semen did not appear to influence vaginal proinflammatory cytokine concentrations. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Necrotizing Pneumonia Caused by Panton-Valentine Leucocidin-Producing Staphylococcus aureus Originating from a Bartholin's AbscessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. S. aureus, in particular PVL-positive strains, should be considered when a young, immunocompetent person develops a fulminant necrotizing pneumonia. Minor infections—such as Bartholin's abscess—can precede this life-threating syndrome. Bactericidal antistaphylococcal antibiotics are recommended for treatment, and surgical procedures may become necessary. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Hydatidosis of the Pelvic Cavity: A Big MasqueradeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report and discuss a case of primary hydatidosis of the pelvic cavity in a woman who presented with severe weight loss and abdominal pain. This unusual presentation was initially considered as a tumor process until surgical exploration and microscopic studies confirmed the diagnosis. The gynecologists should be aware of possibility of primary hydatid cyst of the pelvic cavity and should be considered in the differential diagnosis of cystic pelvic masses, especially in areas where the disease is endemic. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Progressive Hypertrophic Genital Herpes in an HIV-Infected Woman despite Immune Recovery on Antiretroviral TherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a progressive, hypertrophic HSV-2 lesion in an HIV-coinfected woman, despite near-complete immune restoration on antiretroviral therapy for up to three years. In this case, there was prompt response to topical imiquimod. The immunopathogenesis and clinical presentation of HSV-2 disease in HIV-coinfected individuals are reviewed, with a focus on potential mechanisms for persistent disease despite apparent immune reconstitution. HIV-infected individuals and their care providers should be aware that HSV-2 may cause atypical disease even in the context of near-comlpete immune reconstitution on HAART. (Sou...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

The Role of Obstetrician/Gynecologists in the Management of Hepatitis C Virus InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic infection with hepatitis C virus (HCV) is a major cause of liver disease-related death and is also the most frequent indication for liver transplantation in USA. Infected individuals can remain asymptomatic for 20 years or more, but they remain at risk for progressive liver disease. They also represent a potential source of infection for others. For reducing the future disease burden due to HCV, obstetrician/gynecologists and primary health care practitioners should be aware of the factors that promote HCV transmission: how to provide counseling and testing, and when specialist referral is needed. (Source: Infectio...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Ampicillin Resistance and Outcome Differences in Acute Antepartum PyelonephritisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. A majority of uropathogens were ampicillin resistant, but no differences in outcomes were observed in these patients. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Spermicidal Activity of the Safe Natural Antimicrobial Peptide SubtilosinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bacterial vaginosis (BV), a condition affecting millions of women each year, is primarily caused by the gram-variable organism Gardnerella vaginalis. A number of organisms associated with BV cases have been reported to develop multidrug resistance, leading to the need for alternative therapies. Previously, we reported the antimicrobial peptide subtilosin has proven antimicrobial activity against G. vaginalis, but not against the tested healthy vaginal microbiota of lactobacilli. After conducting tissue sensitivity assays using an ectocervical tissue model, we determined that human cells remained viable after prolonged expo...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Chlamydia trachomatis Serology in Women with and without Ovarian CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pelvic inflammation has been implicated in the genesis of ovarian cancer. We conducted serologic measurements of Chlamydia trachomatis antibodies as a surrogate marker of chlamydial pelvic inflammatory disease. Women with ovarian cancer (n=521) and population-based controls (n=766) were tested. IgG antibodies to serovar D of chlamydia elementary bodies (EBs) were detected using an ELISA assay. The odds of having ovarian cancer among women with the highest titers (≥0.40 OD units) were 0.6 (95% CI 0.4–0.9). These data do not support our earlier finding of elevated titers for antibodies to C. trachomatis amon...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Postpartum Invasive Group A Streptococcal Disease in the Modern EraEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To describe the clinical features of individuals hospitalized for postpartum invasive group A Streptococcus (GAS) infection, a retrospective, population-based study of hospitalized patients in the state of Florida was conducted. Cases of postpartum invasive GAS infection (occurring within 42 days of delivery) were compared to women with other manifestations of invasive GAS disease with respect to their age at the time of admission. Four cases of postpartum invasive GAS infection were detected in this population, yielding a prevalence of 1.6% (4/257) of postpartum disease in this invasive GAS infection database. Patients pr...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Adhesion of Human Probiotic Lactobacillus rhamnosus to Cervical and Vaginal Cells and Interaction with Vaginosis-Associated PathogensEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. The ability of Lcr35 to adhere to cervicovaginal cells and its antagonist activities against vaginosis-associated pathogens suggest that this probiotic strain is a promising candidate for use in therapy. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Infection with Hepatitis C Virus among HIV-Infected Pregnant Women in ThailandEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Antibiotic Resistance Patterns in Invasive Group B Streptococcal IsolatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Antibiotics are used for both group B streptococcal (GBS) prevention and treatment. Active population-based surveillance for invasive GBS disease was conducted in four states during 1996–2003. Of 3813 case-isolates, 91.0% (3471) were serotyped, 77.1% (2937) had susceptibility testing, and 46.6% (3471) had both. All were sensitive to penicillin, ampicillin, cefazolin, cefotaxime, and vancomycin. Clindamycin and erythromycin resistance was 12.7% and 25.6%, respectively, and associated with serotype V (P<.001). Clindamycin resistance increased from 10.5% to 15.0% (X2 for trend 12.70; ...
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Postoperative Infectious Morbidities of Cesarean Delivery in Human Immunodeficiency Virus-Infected WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. In our facilities, emergent cesarean delivery and chorioamnionitis but not HIV infection were identified as risk factors for post-operative endometritis. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 9, 2009 Category: OBGYN Source Type: journals

Antibiotic Resistance Patterns in Invasive Group B Streptococcal IsolatesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Antibiotics are used for both group B streptococcal (GBS) prevention and treatment. Active population-based surveillance for invasive GBS disease was conducted in four states during 1996–2003. Of 3813 case-isolates, 91.0% (3471) were serotyped, 77.1% (2937) had susceptibility testing, and 46.6% (3471) had both. All were sensitive to penicillin, ampicillin, cefazolin, cefotaxime, and vancomycin. Clindamycin and erythromycin resistance was 12.7% and 25.6%, respectively, and associated with serotype V (P<.001). Clindamycin resistance increased from 10.5% to 15.0% (X2 for trend 12.70; ...
Source: Infectious Diseases in Obstetrics and Gynecology - February 6, 2009 Category: OBGYN Source Type: journals

Adhesion of Human Probiotic Lactobacillus rhamnosus to Cervical and Vaginal Cells and Interaction with Vaginosis-Associated PathogensEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. The ability of Lcr35 to adhere to cervicovaginal cells and its antagonist activities against vaginosis-associated pathogens suggest that this probiotic strain is a promising candidate for use in therapy. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - January 27, 2009 Category: OBGYN Source Type: journals

Infection with Hepatitis C Virus among HIV-Infected Pregnant Women in ThailandEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - January 27, 2009 Category: OBGYN Source Type: journals

Postpartum Invasive Group A Streptococcal Disease in the Modern EraEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To describe the clinical features of individuals hospitalized for postpartum invasive group A Streptococcus (GAS) infection, a retrospective, population-based study of hospitalized patients in the state of Florida was conducted. Cases of postpartum invasive GAS infection (occurring within 42 days of delivery) were compared to women with other manifestations of invasive GAS disease with respect to their age at the time of admission. Four cases of postpartum invasive GAS infection were detected in this population, yielding a prevalence of 1.6% (4/257) of postpartum disease in this invasive GAS infection database. Patients pr...
Source: Infectious Diseases in Obstetrics and Gynecology - January 3, 2009 Category: OBGYN Source Type: journals

Chlamydia trachomatis Serology in Women with and without Ovarian CancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pelvic inflammation has been implicated in the genesis of ovarian cancer. We conducted serologic measurements of Chlamydia trachomatis antibodies as a surrogate marker of chlamydial pelvic inflammatory disease. Women with ovarian cancer (n=521) and population-based controls (n=766) were tested. IgG antibodies to serovar D of chlamydia elementary bodies (EBs) were detected using an ELISA assay. The odds of having ovarian cancer among women with the highest titers (≥0.40 OD units) were 0.6 (95% CI 0.4–0.9). These data do not support our earlier finding of elevated titers for antibodies to C. trachomatis amon...
Source: Infectious Diseases in Obstetrics and Gynecology - December 18, 2008 Category: OBGYN Source Type: journals

Ampicillin Resistance and Outcome Differences in Acute Antepartum PyelonephritisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. A majority of uropathogens were ampicillin resistant, but no differences in outcomes were observed in these patients. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - October 9, 2008 Category: OBGYN Source Type: journals

Spermicidal Activity of the Safe Natural Antimicrobial Peptide SubtilosinEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bacterial vaginosis (BV), a condition affecting millions of women each year, is primarily caused by the gram-variable organism Gardnerella vaginalis. A number of organisms associated with BV cases have been reported to develop multidrug resistance, leading to the need for alternative therapies. Previously, we reported the antimicrobial peptide subtilosin has proven antimicrobial activity against G. vaginalis, but not against the tested healthy vaginal microbiota of lactobacilli. After conducting tissue sensitivity assays using an ectocervical tissue model, we determined that human cells remained viable after prolonged expo...
Source: Infectious Diseases in Obstetrics and Gynecology - October 9, 2008 Category: OBGYN Source Type: journals

The Role of Obstetrician/Gynecologists in the Management of Hepatitis C Virus InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Chronic infection with hepatitis C virus (HCV) is a major cause of liver disease-related death and is also the most frequent indication for liver transplantation in USA. Infected individuals can remain asymptomatic for 20 years or more, but they remain at risk for progressive liver disease. They also represent a potential source of infection for others. For reducing the future disease burden due to HCV, obstetrician/gynecologists and primary health care practitioners should be aware of the factors that promote HCV transmission: how to provide counseling and testing, and when specialist referral is needed. (Source: Infectio...
Source: Infectious Diseases in Obstetrics and Gynecology - September 23, 2008 Category: OBGYN Source Type: journals

Progressive Hypertrophic Genital Herpes in an HIV-Infected Woman despite Immune Recovery on Antiretroviral TherapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a progressive, hypertrophic HSV-2 lesion in an HIV-coinfected woman, despite near-complete immune restoration on antiretroviral therapy for up to three years. In this case, there was prompt response to topical imiquimod. The immunopathogenesis and clinical presentation of HSV-2 disease in HIV-coinfected individuals are reviewed, with a focus on potential mechanisms for persistent disease despite apparent immune reconstitution. HIV-infected individuals and their care providers should be aware that HSV-2 may cause atypical disease even in the context of near-comlpete immune reconstitution on HAART. (Sou...
Source: Infectious Diseases in Obstetrics and Gynecology - September 4, 2008 Category: OBGYN Source Type: journals

Hydatidosis of the Pelvic Cavity: A Big MasqueradeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report and discuss a case of primary hydatidosis of the pelvic cavity in a woman who presented with severe weight loss and abdominal pain. This unusual presentation was initially considered as a tumor process until surgical exploration and microscopic studies confirmed the diagnosis. The gynecologists should be aware of possibility of primary hydatid cyst of the pelvic cavity and should be considered in the differential diagnosis of cystic pelvic masses, especially in areas where the disease is endemic. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - August 29, 2008 Category: OBGYN Source Type: journals

Necrotizing Pneumonia Caused by Panton-Valentine Leucocidin-Producing Staphylococcus aureus Originating from a Bartholin's AbscessEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. S. aureus, in particular PVL-positive strains, should be considered when a young, immunocompetent person develops a fulminant necrotizing pneumonia. Minor infections—such as Bartholin's abscess—can precede this life-threating syndrome. Bactericidal antistaphylococcal antibiotics are recommended for treatment, and surgical procedures may become necessary. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - July 29, 2008 Category: OBGYN Source Type: journals

Effect of Semen on Vaginal Fluid Cytokines and Secretory Leukocyte Protease InhibitorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: proinflammatory cytokine measurement does not appear to be affected by the presence of semen, but secretory leukocyte protease inhibitor is significantly higher when semen is present. Detection of semen by acid phosphatase was associated with higher vaginal SLPI concentrations, however, the presence of semen did not appear to influence vaginal proinflammatory cytokine concentrations. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - July 4, 2008 Category: OBGYN Source Type: journals

The Metabolism and Transplacental Transfer of Oseltamivir in the Ex Vivo Human ModelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Oseltamivir phosphate was extensively metabolized in the ex vivo model. Transplacental transfer of the metabolite was incomplete and accumulation was minimal. (Source: Infectious Diseases in Obstetrics and Gynecology)
Source: Infectious Diseases in Obstetrics and Gynecology - June 4, 2008 Category: OBGYN Source Type: journals