MODELS: a six-step framework for developing an infectious disease model
AbstractSince the COVID-19 pandemic began, a plethora of modeling studies related to COVID-19 have been released. While some models stand out due to their innovative approaches, others are flawed in their methodology. To assist novices, frontline healthcare workers, and public health policymakers in navigating the complex landscape of these models, we introduced a structured framework named MODELS. This framework is designed to detail the essential steps and considerations for creating a dependable epidemic model, offering direction to researchers engaged in epidemic modeling endeavors.Graphical Abstract (Source: Infectiou...
Source: Infectious Diseases of Poverty - April 17, 2024 Category: Infectious Diseases Source Type: research
Mutations and intron polymorphisms in voltage-gated sodium channel genes of different geographic populations of Culex pipiens pallens/Culex pipiens quinquefasciatus in China
ConclusionsCx. p. pallens andCx. p. quinquefasciatus have developed resistance to insecticides in most regions of China. The neighboring downstream introns of thevgsc gene gradually decreased to one intron with the mutation of thevgsc gene. Mutations may originate from multiple mutation events rather than from a single origin, and populations lacking mutations may be genetically isolated.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - April 15, 2024 Category: Infectious Diseases Source Type: research
Towards an actionable One Health approach
ConclusionsBy promoting broader engagement and connection of multidisciplinary stakeholders, OHAC envisions a collaborative global platform for the generation of innovative One Health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of One Health.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - April 12, 2024 Category: Infectious Diseases Source Type: research
Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study
ConclusionsPersons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the public or private sector. Patient costs could be reduced through expanded insurance reimbursement to minimize direct medical costs in the private sector, use of remote monitoring and multi-week/month dosing strategies to avert economic costs in the public sector and greater access to social protection mechanism in general. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - March 25, 2024 Category: Infectious Diseases Source Type: research
Climate-influenced vector-borne diseases in Africa: a call to empower the next generation of African researchers for sustainable solutions
This article underscores the urgency of increased national investment in research, proposing the establishment of research government agencies to drive evidence-based interventions. Collaboration between governments and scientific communities, sustained by pan-African funding bodies, is crucial. Through these efforts, African nations are likely to enhance the resilience and adaptive capacity of their systems and communities by navigating these challenges effectively, fostering scientific excellence and implementing transformative solutions against climate-sensitive vector-borne diseases. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - March 14, 2024 Category: Infectious Diseases Source Type: research
Advancing the National Immunization Program in an era of achieving universal vaccine coverage in China and beyond
ConclusionThe articles emphasize the need for government leadership, strategic policymaking, and public awareness to enhance vaccine coverage and equity. The VaxLab will continue strengthening China ’s NIP by focusing on vaccine financing, emphasizing diversity, equity, and inclusion, and improving maternal vaccination coverage. Research will extend to Southeast Asian and Western Pacific regions, especially in middle-income countries facing challenges in vaccine financing and delivery. The co llective efforts outlined in this collection show a commitment to evolving and adapting immunization strategies to meet global hea...
Source: Infectious Diseases of Poverty - March 13, 2024 Category: Infectious Diseases Source Type: research
Natural variables separate the endemic areas of Clonorchis sinensis and Opisthorchis viverrini along a continuous, straight zone in Southeast Asia
ConclusionsOur findings highlight the critical role of specific climatic and environmental factors in influencing the geographical distribution ofC. sinensis andO. viverrini. This spatial delineation offers valuable insights for integrated surveillance and control strategies, particularly in regions with sympatric transmission. The results underscore the need for tailored interventions, considering regional epidemiological variations. Future collaborations integrating eco-epidemiology, molecular epidemiology, and parasitology are essential to further elucidate the complex interplay of liver fluke distributions in Asia. (So...
Source: Infectious Diseases of Poverty - March 12, 2024 Category: Infectious Diseases Source Type: research
Male genitourinary schistosomiasis-related symptoms among long-term Western African migrants in Spain: a prospective population-based screening study
ConclusionsUrogenital clinical signs and symptoms are prevalent among male African long-term migrants with a positiveSchistosoma serology results. Genital involvement can be frequent even among those with long periods of non-residence in their sub-Saharan African countries of origin. Further research is needed to develop diagnostic tools and validate therapeutic approaches to chronic schistosomiasis.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - March 7, 2024 Category: Infectious Diseases Source Type: research
Development of innovative tripartite partnership for China ’s engagement in global health: recommendations from China-Tanzania Cooperation Project on Malaria Control
(Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - March 5, 2024 Category: Infectious Diseases Source Type: research
The risk of mpox importation and subsequent outbreak potential in Chinese mainland: a retrospective statistical modelling study
ConclusionsOur study demonstrates that the reduced international air-travel volume and stringent border entry policy during the COVID-19 pandemic reduced mpox importations prominently. However, the risk could be substantially higher with the recovery of air-travel volume to pre-pandemic level. Mpox could emerge as a public health threat for Chinese mainland given its large MSM community.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 29, 2024 Category: Infectious Diseases Source Type: research
Chromosome-level genome assembly of Oncomelania hupensis: the intermediate snail host of Schistosoma japonicum
ConclusionsIntegrated use of multiple sequencing technologies, we have successfully constructed the genome at the chromosomal-level ofO. hupensis. These data will not only provide the compressive genomic information, but also benefit future work on population genetics of this snail as well as evolutional studies betweenS. japonicum and the snail host.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 27, 2024 Category: Infectious Diseases Source Type: research
Toward tuberculosis elimination by understanding epidemiologic characteristics and risk factors in Hainan Province, China
ConclusionsThe notification rate of TB in Hainan Province has been declining overall but still remained high in central and southern regions. Particular attention should be paid to the prevalence of TB among males, farmers, and out-of-province migrant populations. The notification rate was also influenced by economic development and medical conditions, indicating the need of more TB specialized hospitals, active surveillance and other tailored prevention and control measures to promote the progress of TB elimination in Hainan Province. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 27, 2024 Category: Infectious Diseases Source Type: research
Incidence and warning signs for complications of human brucellosis: a multi-center observational study from China
ConclusionsMore than 50% of patients with brucellosis experienced complications. Factors such as diagnostic delay, underlying disease, arthralgia, eye pain, and elevated levels of CRP and ESR were identified as significant markers for the development of complications. Therefore, patients presenting with these conditions should be closely monitored for potential complications, regardless of their culture results and standard tube agglutination test titers. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 20, 2024 Category: Infectious Diseases Source Type: research
Effectiveness of ivermectin mass drug administration in the control of soil-transmitted helminth infections in endemic populations: a systematic review and meta-analysis
ConclusionsThis study underscores the key role of ivermectin-based MDA in addressing limitations in current global STH guidelines in terms of limited efficacy againstS. stercoralis andT. trichiura. Based on these findings, revising international STH guidelines to include ivermectin is a promising option to progress the control and eventual elimination of STHs and other NTDs. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 18, 2024 Category: Infectious Diseases Source Type: research
Unsuccessful tuberculosis treatment outcomes across Brazil's geographical landscape before and during the COVID-19 pandemic: are we truly advancing toward the sustainable development/end TB goal?
ConclusionsThe pandemic has brought additional challenges, emphasizing the importance of enhancing efforts and disease control strategies, prioritizing early identification, treatment adherence, and follow-up. This commitment is vital for achieving the goal of tuberculosis elimination. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 18, 2024 Category: Infectious Diseases Source Type: research
