Intensive Care Medicine Experimental This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Carboxyhemoglobin predicts oxygenator performance and imminent oxygenator change in extracorporeal membrane oxygenation
The continuous exposure of blood to a non-biological surface during extracorporeal membrane oxygenation (ECMO) may lead to progressive thrombus formation in the oxygenator, hemolysis and consequently impaired ... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 24, 2024 Category: Surgery Authors: Rolf Erlebach, Alix Buhlmann, Rea Andermatt, Benjamin Seeliger, Klaus Stahl, Christian Bode, Reto Schuepbach, Pedro David Wendel-Garcia and Sascha David Tags: Research Articles Source Type: research

Epstein –Barr virus, Cytomegalovirus, and Herpes Simplex-1/2 reactivations in critically ill patients with COVID-19
To assess the incidences of Herpes Simplex-1 and 2 (HSV-1, HSV-2), Cytomegalovirus (CMV), Epstein –Barr Virus (EBV) reactivations in critically ill COVID-19 patients. To determine the association between viral ... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 22, 2024 Category: Surgery Authors: Alessia Mattei, Lorenzo Schiavoni, Elisabetta Riva, Massimo Ciccozzi, Roberta Veralli, Angela Urselli, Vincenzo Citriniti, Antonio Nenna, Giuseppe Pascarella, Fabio Costa, Rita Cataldo, Felice Eugenio Agr ò and Massimiliano Carassiti Tags: Research Articles Source Type: research

Immediate inflammatory response to mechanical circulatory support in a porcine model of severe cardiogenic shock
In selected cases of cardiogenic shock, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is combined with trans valvular micro axial flow pumps (ECMELLA). Observational studies indicate that ECMELL... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 22, 2024 Category: Surgery Authors: Emilie Gregers, Peter H. Frederiksen, Nanna L. J. Udesen, Louise Linde, Ann Banke, Amalie L. Povlsen, Jeppe P. Larsen, Christian Hassager, Lisette O. Jensen, Jens F. Lassen, Henrik Schmidt, Hanne B. Ravn, Peter M. H. Heegaard and Jacob E. M øller Tags: Research Articles Source Type: research

Ineffectiveness of hemoadsorption in large animals with abdominal sepsis: a randomized controlled porcine study
The use of hemoadsorption (HA) has become popular in the treatment of vasoplegic states associated with massive cytokine release, including septic shock. However, this approach does not seem to be based on rob... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 18, 2024 Category: Surgery Authors: Vaclav Tegl, Jan Horak, Lukas Nalos, Michala Horakova, Milan Stengl, Martin Matejovic and Jan Benes Tags: Research Articles Source Type: research

Hyperoxemia and hypoxemia impair cellular oxygenation: a study in healthy volunteers
Administration of oxygen therapy is common, yet there is a lack of knowledge on its ability to prevent cellular hypoxia as well as on its potential toxicity. Consequently, the optimal oxygenation targets in cl... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 15, 2024 Category: Surgery Authors: Bashar N. Hilderink, Reinier F. Crane, Bas van den Bogaard, Janesh Pillay and Nicole P. Juffermans Tags: Research Articles Source Type: research

Oxygenation and ventilation during prolonged experimental cardiopulmonary resuscitation with either continuous or 30:2 compression-to-ventilation ratios together with 10 cmH20 positive end-expiratory pressure
In refractory out-of-hospital cardiac arrest, the patient is commonly transported to hospital with mechanical continuous chest compressions (CCC). Limited data are available on the optimal ventilation strategy... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 12, 2024 Category: Surgery Authors: Jukka Kopra, Erik Litonius, Pirkka T. Pekkarinen, Merja Laitinen, Juho A. Heinonen, Luca Fontanelli and Markus B. Skrifvars Tags: Research Articles Source Type: research

Impact of respiratory cycle during mechanical ventilation on beat-to-beat right ventricle stroke volume estimation by pulmonary artery pulse wave analysis
The same principle behind pulse wave analysis can be applied on the pulmonary artery (PA) pressure waveform to estimate right ventricle stroke volume (RVSV). However, the PA pressure waveform might be influenc... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 9, 2024 Category: Surgery Authors: Arnoldo Santos, M. Ignacio Monge-Garc ía, João Batista Borges, Jaime Retamal, Gerardo Tusman, Anders Larsson and Fernando Suarez-Sipmann Tags: Research Articles Source Type: research

The ongoing journey in targeting hemodynamic interventions: missing miles for missing the last micron?
(Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 9, 2024 Category: Surgery Authors: Johannes Heymer and Daniel Raepple Tags: Hypothesis Source Type: research

Isoflurane, like sepsis, decreases CYP1A2 liver enzyme activity in intensive care patients: a clinical study and network model
Liver function of intensive care patients is routinely monitored by static blood pathology. For specific indications, liver specific cytochrome activity may be measured by the commercially available maximum li... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 8, 2024 Category: Surgery Authors: Thomas K öhler, Elke Schwier, Janina Praxenthaler, Carmen Kirchner, Günther Winde, Björn Koos and Dietrich Henzler Tags: Research Articles Source Type: research

Reinforcement learning for intensive care medicine: actionable clinical insights from novel approaches to reward shaping and off-policy model evaluation
Reinforcement learning (RL) holds great promise for intensive care medicine given the abundant availability of data and frequent sequential decision-making. But despite the emergence of promising algorithms, R... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - March 25, 2024 Category: Surgery Authors: Luca F. Roggeveen, Ali el Hassouni, Harm-Jan de Grooth, Armand R. J. Girbes, Mark Hoogendoorn and Paul W. G. Elbers Tags: Research Articles Source Type: research

Determinants of acute kidney injury during high-power mechanical ventilation: secondary analysis from experimental data
The individual components of mechanical ventilation may have distinct effects on kidney perfusion and on the risk of developing acute kidney injury; we aimed to explore ventilatory predictors of acute kidney f... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - March 21, 2024 Category: Surgery Authors: Simone Gattarello, Fabio Lombardo, Federica Romitti, Rosanna D ’Albo, Mara Velati, Isabella Fratti, Tommaso Pozzi, Rosmery Nicolardi, Antonio Fioccola, Mattia Busana, Francesca Collino, Peter Herrmann, Luigi Camporota, Michael Quintel, Onnen Moerer, Lei Tags: Research Articles Source Type: research

Flow-controlled ventilation decreases mechanical power in postoperative ICU patients
Mechanical power (MP) is the energy delivered by the ventilator to the respiratory system and combines factors related to the development of ventilator-induced lung injury (VILI). Flow-controlled ventilation (... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - March 19, 2024 Category: Surgery Authors: Julien P. Van Oosten, Juliette E. Francovich, Peter Somhorst, Philip van der Zee, Henrik Endeman, Diederik A. M. P. J. Gommers and Annemijn H. Jonkman Tags: Research Articles Source Type: research

The ESICM datathon and the ESICM and ICMx data science strategy
(Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - March 12, 2024 Category: Surgery Authors: Paul Elbers, Patrick Thoral, Lieuwe D. J. Bos, Massimiliano Greco, Pedro D. Wendel-Garcia and Ari Ercole Tags: Editorial Source Type: research

Impact of age on the host response to sepsis in a murine model of fecal-induced peritonitis
Despite older adults being more vulnerable to sepsis, most preclinical research on sepsis has been conducted using young animals. This results in decreased scientific validity since age is an independent predi... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - March 8, 2024 Category: Surgery Authors: Neha Sharma, Alex Chen, Leah Heinen, Ruth Liu, Dhruva J. Dwivedi, Ji Zhou, Manoj M. Lalu, Asher A. Mendelson, Braedon McDonald, Colin A. Kretz, Alison E. Fox-Robichaud and Patricia C. Liaw Tags: Research Articles Source Type: research

Six methods to determine expiratory time constants in mechanically ventilated patients: a prospective observational physiology study
Expiratory time constant ( τ) objectively assesses the speed of exhalation and can guide adjustments of the respiratory rate and the I:E ratio with the goal of achieving complete exhalation. Multiple methods of ob... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - March 7, 2024 Category: Surgery Authors: Filip Depta, Caitlyn M. Chiofolo, Nicolas W. Chbat, Neil R. Euliano, Michael A. Gentile, Du šan Rybár, Viliam Donič and Marko Zdravkovic Tags: Research Articles Source Type: research