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Ebselen: A Promising Repurposing Drug to Treat Infections Caused by Multidrug-Resistant Microorganisms
Interdiscip Perspect Infect Dis. 2024 Mar 30;2024:9109041. doi: 10.1155/2024/9109041. eCollection 2024.ABSTRACTBacterial multiresistance to drugs is a rapidly growing global phenomenon. New resistance mechanisms have been described in different bacterial pathogens, threatening the effective treatment of even common infectious diseases. The problem worsens in infections associated with biofilms because, in addition to the pathogen's multiresistance, the biofilm provides a barrier that prevents antimicrobial access. Several "non-antibiotic" drugs have antimicrobial activity, even though it is not their primary therapeutic pu...
Source: Interdisciplinary Perspectives on Infectious Diseases - April 8, 2024 Category: Infectious Diseases Authors: Agostinho Alves de Lima E Silva Andr é Rio-Tinto Source Type: research

Meningitis and Bacteremia by Unusual Serotype of < em > Salmonella enterica < /em > Strain: A Whole Genome Analysis
CONCLUSIONS: We presented a genomic report of rare case of NTS meningitis in an infant who is living in a rural town in Jazan region, Saudi Arabia. Further research is required to understand the impact of host genetic factors on invasive nontyphoidal Salmonella infection.PMID:38558876 | PMC:PMC10980553 | DOI:10.1155/2024/3554734 (Source: Interdisciplinary Perspectives on Infectious Diseases)
Source: Interdisciplinary Perspectives on Infectious Diseases - April 1, 2024 Category: Infectious Diseases Authors: Thamer Brek Gassem A Gohal Muhammad Yasir Esam I Azhar Ibrahim A Al-Zahrani Source Type: research

The Decreased < em > Treg < /em > Cells Number Associated with Retinal Lesion Size in Ocular Toxoplasmosis
CONCLUSION: Ocular toxoplasmosis patients have a low number of Treg cells that are inversely related to the retinal lesion size. The size of the retinal lesion increases as the number of Treg cells decreases.PMID:38314317 | PMC:PMC10830908 | DOI:10.1155/2024/3495376 (Source: Interdisciplinary Perspectives on Infectious Diseases)
Source: Interdisciplinary Perspectives on Infectious Diseases - February 5, 2024 Category: Infectious Diseases Authors: Ovi Sofia Muna Amalia Herryanto Thomassawa Loeki Enggar Fitri Seskoati Prayitnaningsih Hani Susianti Source Type: research