Internal and Emergency Medicine
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Referees 2009
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Content Type Journal ArticleCategory Acknowledgement to RefereesDOI 10.1007/s11739-009-0328-2
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447
Journal Volume Volume 4
Journal Issue Volume 4, Number 6 / December, 2009 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - November 18, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Characteristics of patients in a ward of Academic Internal Medicine: implications for medical care, training programmes and research
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Abstract To describe the characteristics of “delayed discharge patients” and the factors associated with “delayed discharges”, we performed
a 12-month observational study on patients classified as “delayed discharge patients” admitted to an Academic Internal Medicine
ward. We assessed the demographic variables, the number and severity of diseases using the Geriatric Index of Comorbidity
(GIC), the cognitive, affective and functional status using, respectively, the Mini Mental Stare Examination, the Geriatric
Depression Scale and the Barthel Index. We assessed the total length of stay (T-LHS), the...
Source: Internal and Emergency Medicine - November 6, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
An unusual cause of small bowel obstruction
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Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0326-4Authors
Sidhartha Sinha, North Middlesex University Hospital NHS Trust London UKKezia Gaitskell, North Middlesex University Hospital NHS Trust London UKRudy Borgstein, North Middlesex University Hospital NHS Trust London UKRomi Navaratnam, North Middlesex University Hospital NHS Trust London UK
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - November 5, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Extended prophylaxis of venous thromboembolism with fondaparinux in patients undergoing major orthopaedic surgery in Italy: a cost-effectiveness analysis
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In conclusion, our model shows that, when administered
for extended prophylaxis of VTE following MOS, fondaparinux is more effective and cost saving than enoxaparin.
Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-009-0324-6Authors
Stefano Capri, Cattaneo-LIUC University Institute of Economics Castellanza ItalyWalter Ageno, University of Insubria Department of Clinical Medicine Varese ItalyDavide Imberti, Hospital of Piacenza Emergency Department, Thrombosis Center Piacenza ItalyGualtiero Palareti, University Hospital Department of Angiology and Blood Coagulation “Marino Golinelli” Bologna It...
Source: Internal and Emergency Medicine - November 5, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Measuring the impact of evidence: the Cochrane systematic review of organised stroke care
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Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0323-7Authors
Rita Banzi, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyLorenzo Moja, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyAlessandro Liberati, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyGian Franco Gensini, University of Florence Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiologico e dei Vasi, Azie...
Source: Internal and Emergency Medicine - November 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Upper extremities deep venous thrombosis CVC-related: try to find
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0317-5Authors
Rino Frizzelli, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyOrnella Tortelli, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyVincenzo Di Comite, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyRedenta Ghirardi, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyClaudio Pinzi, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile ...
Source: Internal and Emergency Medicine - October 31, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
New oral anticoagulants: just a new therapeutic option or a real breakthrough?
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Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0327-3Authors
Giancarlo Agnelli, Università di Perugia Medicina Interna e Cardiovascolare-Stroke Unit, Dipartimento di Medicina Interna Via G. Dottori 1 06129 Perugia ItalyCecilia Becattini, Università di Perugia Medicina Interna e Cardiovascolare-Stroke Unit, Dipartimento di Medicina Interna Via G. Dottori 1 06129 Perugia Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - October 30, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Insights into the pathogenesis and management of thrombosis in polycythemia vera and essential thrombocythemia
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Abstract The classic myeloproliferative neoplasms (MPNs) include polycythemia vera and essential thrombocythemia; their molecular basis
has been described only recently with the demonstration of recurrent mutations in JAK2 or MPL. While life expectancy may not be significantly shortened, arterial and venous thrombosis constitute the major causes of
morbidity and mortality, together with disease evolution to myelofibrosis or transformation to acute leukemia. Therapy is
currently aimed at reducing the rate of thrombosis without increasing the risk of hematologic transformation by inappropriate
exposure to cyto...
Source: Internal and Emergency Medicine - September 30, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
A 41-year-old woman with paroxysmal abdominal pain, weight loss and an epigastric bruit
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Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0318-4Authors
Antonella Marcoccia, UOD ANGIOLOGIA, Ospedale Sandro Pertini, Via Dei Monti Tiburtini 00157 Rome ItalyMarco Di Tola, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyFrancesca Paris, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyGiuseppe Donato, Università Sapienza di Roma Dipartimento Medicina Clinica, Policlinico U. I Rome ItalyValerio Libanori, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyAntonio Pi...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
New evidence in infective and cardiovascular medicine
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Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0315-7Authors
Beatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Viale Morgagni 85 50134 Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Florence ItalyAndrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universitaria Careggi General Med...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Acquired haemophilia A: a case report
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0307-7Authors
Daniela Colomba, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone” Piazza delle Cliniche no 2 90127 Palermo ItalyDomenico Di Raimondo, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone” Piazza delle Cliniche no 2 90127 Palermo ItalyLuciana Marino, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Spigelian hernia mimicking appendicular mass
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Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0322-8Authors
Sidhartha Sinha, North Middlesex University Hospital NHS Trust London UKArunthathi Pushparajasekaran, North Middlesex University Hospital NHS Trust London UKRudy Borgstein, North Middlesex University Hospital NHS Trust London UKDavid L. Stoker, North Middlesex University Hospital NHS Trust London UK
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Presence of low titre of antiphospholipid antibodies in cancer patients: a prospective study
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In conclusion, a high prevalence of low-titre aPL was found in cancer patients at diagnosis, but
no statistical difference in thrombosis-free survival or in overall survival was observed between aPL positive and aPL negative
patients.
Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-009-0316-6Authors
Mario Bazzan, CMID, Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Giovanni Bosco Hospital P.zza Donatori di Sangue 3 10154 Turin ItalyBarbara Montaruli, Laboratory Analysis and Oncology ...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Upper extremity deep vein thrombosis
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Abstract Upper extremities deep venous thrombosis (UEDVT) is a rare condition. According to the literature, approximately 4–10% of
all cases of venous thrombosis may involve the subclavian, axillary or brachial veins. In the last few decades, the incidence
of UEDVT has increased because of more frequent use of central venous catheters (CVCs) and cardiac pacemaker implantation.
In addition, another common risk factor for UEDVT is cancer. UEDVT is classified as primary, approximately one-third of cases,
which refers either to effort thrombosis or idiopathic UEDVT, or secondary, due to the presence of overt p...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Matrix metalloproteinases and peripheral arterial disease
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Content Type Journal ArticleCategory ErratumDOI 10.1007/s11739-009-0308-6Authors
Chiara Busti, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyEmanuela Falcinelli, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyStefania Momi, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyPaolo Gresele, University of Perugia Division of Internal and Cardiovascula...
Source: Internal and Emergency Medicine - September 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Pulmonary arterial hypertension
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Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0321-9Authors
Massimo Miniati, Università degli Studi di Firenze Dipartimento di Area Critica Medico Chirurgica Viale Morgagni 85 50134 Florence Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Emergency department use by the uninsured after health care reform in Massachusetts
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This study is limited by its analysis of a single large institution and a limited set of diagnoses.
Content Type Journal ArticleCategory EM - OriginalDOI 10.1007/s11739-009-0313-9Authors
Peter Smulowitz, Beth Israel Deaconess Medical Center Department of Emergency Medicine, WCC2 Boston MA 02215 USABruce E. Landon, Harvard Medical School Department of Medicine and Health Care Policy Boston MA USALaura Burke, Beth Israel Deaconess Medical Center Department of Emergency Medicine, WCC2 Boston MA 02215 USAChristopher Baugh, Brigham and Women’s Hospital and Massachusetts General Hospital Department of Emergency Medicine B...
Source: Internal and Emergency Medicine - September 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Hepcidin mutation in a β-thalassemia major patient with persistent severe iron overload despite chelation therapy
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0306-8Authors
Lorena Duca, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyPaola Delbini, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyIsabella Nava, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyMaria Domenica Cappellini, University of Milan Department of Internal Medicine, Maggiore...
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
When pre-test probability can be deceptive
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0305-9Authors
Micaela La Regina, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia ItalyMaria Cristina Pierantoni, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia ItalyMassimo Ratti, La Spezia I ItalyFrancesco Orlandini, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Heart failure and clinical practice
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0310-zAuthors
Giorgio Costantino, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyAnna Maria Rusconi, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyStefano Guzzetti, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyNicola Montano, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan Italy
Journal Internal and ...
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
A new approach to resident morning report: introducing “VAVUM”
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0311-yAuthors
Mark D. Huffman, Northwestern University Division of Cardiology 676 North St. Clair St., Suite #600 Chicago IL 60611 USASamuel R. Kaufman, University of Michigan Health System Department of Internal Medicine Ann Arbor MI USASanjay Saint, University of Michigan Health System Department of Internal Medicine Ann Arbor MI USA
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Noncompaction of ventricular myocardium in an elderly woman
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Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0309-5Authors
Alessio Currò, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyAlessandro Lauro, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyRaffaella Gallo, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyAndrea Corsonello, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
New direct thrombin inhibitors
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Abstract Direct thrombin inhibitors (DTIs) are a class of anticoagulants that bind selectively to thrombin and block its interaction
with its substrates. Dabigatran etexilate and AZD0837, the new generation of DTIs, are now under intense development, and
are potentially of great interest for internists. Dabigatran etexilate is a potent, non-peptidic small molecule that specifically
and reversibly inhibits both free and clot-bound thrombin by binding to the active site of thrombin molecule. It has been
already licensed in the European Union and in Canada for the prevention of VTE in patients undergoing hip- a...
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Atrial fibrillation in a pregnant woman with a normal heart
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0312-xAuthors
Luca Cacciotti, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome ItalyGiovanni S. Camastra, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome ItalyGerardo Ansalone, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Soluble forms of RAGE in internal medicine
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Abstract The receptor for advanced glycation end-products (RAGE) and its ligands are intimately involved in the pathobiology of a wide
range of diseases that share common features, such as enhanced oxidative stress, immune/inflammatory responses, and altered
cell functions. Soluble forms of RAGE (sRAGE), including the splice variant endogenous secretory (es)RAGE, have been found
circulating in plasma and tissues. Experimental data suggest that these isoforms may neutralize the ligand-mediated damage
by acting as a decoy. Moreover, evidence is mounting to support a role for both sRAGE and esRAGE as biomarkers...
Source: Internal and Emergency Medicine - September 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Efficacy of medical therapy in a case of idiopathic pulmonary fibrosis due to gastroesophageal reflux disease
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0301-0Authors
Franca Dipaola, A.O. “Istituti Clinici di Perfezionamento” U.O. Medicina Interna Viale Matteotti, 83 20099 Sesto San Giovanni Milan ItalyAndrea Galli, Ospedale “Civile di Vimercate” Medicina Interna Vimercate Milan ItalyCarlo Selmi, IRCCS Istituto Clinico Humanitas, Rozzano, Università di Milano Dipartimento Medicina Interna Milan ItalyRaffaello Furlan, Ospedale “Bolognini”, Università di Milano Medicina Generale Seriate Bergamo Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print I...
Source: Internal and Emergency Medicine - September 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Thiamine deficiency as a single cause of life-threatening lactic acidosis in a patient with acute axonal polyneuropathy
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0303-yAuthors
Petronella Johanna Van den Berg, St. Elisabeth Hospital Department of Neurology Tilburg The NetherlandsPeter J. Bijlstra, St. Elisabeth Hospital Department of Intensive Care Hilvarenbeekseweg 60 5022 GC Tilburg The NetherlandsGeert J. F. Brekelmans, St. Elisabeth Hospital Department of Neurology Tilburg The Netherlands
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
A case of thrombolysis in acute pulmonary embolism with right atrial thrombus: comparing current and past guidelines
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Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0304-xAuthors
Francesco Paneni, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyErika Pagannone, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyAngela Gurgo, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalySebastiano Sciarretta, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyCamillo Auto...
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Heterogeneity and meta-analyses: do study results truly differ?
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Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0296-6Authors
Gianni Virgili, University of Florence Department of Oto-Neuro-Ophthalmological Surgical Sciences, Eye Clinic V.le Morgagni 85 50134 Florence ItalyAndrea A. Conti, University of Florence Department of Critical Care Medicine and Surgery Florence ItalyLorenzo Moja, Mario Negri Institute for Pharmacological Research Italian Cochrane Centre Milan ItalyGian Franco Gensini, University of Florence and Azienda Ospedaliero-Universitaria Careggi Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiol...
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Abnormalities of hemostasis and bleeding in chronic liver disease: the paradigm is challenged
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Abstract Chronic liver disease is characterized by a global hemostatic defect including platelet–vessel wall interaction (primary hemostasis),
coagulation and fibrinolysis that may cause abnormalities of the relevant laboratory tests. The causal relationship between
abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with the
timing and incidence of actual bleeding. In this article, we review recent evidence from the literature that disputes the
above paradigm, and opens new venues for laboratory/clinical research and patient management in this f...
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
New evidence in neoplastic and cardiovascular medicine
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Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0294-8Authors
Andrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyBeatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universit...
Source: Internal and Emergency Medicine - August 26, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Future drugs for migraine
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Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0299-3Authors
Luigi Alberto Pini, University of Modena and Reggio Emilia Headache Centre via del Pozzo, 71 41100 Modena Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - August 25, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
The microcirculation as a diagnostic and therapeutic target in sepsis
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Abstract The microcirculation is defined as the smallest vessels where gas and nutrient exchange with tissues takes place. One of its
primary functions is to ensure adequate oxygen delivery to meet the oxygen demands of tissue cells. Previous data from clinical
and experimental studies and the recent development of new imaging modalities, such as Orthogonal Polarization Spectral videomicroscopy
and Sidestream Dark Field imaging, have helped to identify the crucial role that microcirculation plays in sepsis. If not
corrected, microcirculatory dysfunction can lead to respiratory distress in tissue cells and su...
Source: Internal and Emergency Medicine - August 25, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Splenic infarction: a rare cause of acute abdominal pain presenting in an older patient with primary antiphospholipid antibodies syndrome
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0298-4Authors
Marco Rossato, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgical and Medical Sciences Via Ospedale 105 35128 Padua ItalyMartina Paccagnella, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgical and Medical Sciences Via Ospedale 105 35128 Padua ItalyMarta Burei, University of Padova Nuclear Medicine Unit, Department of Diagnostic Medical Sciences Padua ItalyGiovanni Federspil, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department...
Source: Internal and Emergency Medicine - August 21, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Oral factor Xa inhibitors for thromboprophylaxis in major orthopedic surgery: a review
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Abstract Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, is a major cause of morbidity and
mortality in patients undergoing major orthopedic surgery. Routine thromboprophylaxis has been the standard of care over the
last 20 years. Currently available options for the prevention of VTE in major orthopedic surgery include low molecular weight
heparins, vitamin K antagonists, and, more recently, the synthetic pentasaccharide fondaparinux. Although effective, all these
drugs have several limitations and new oral antithrombotics offering predictable, effective and safe ant...
Source: Internal and Emergency Medicine - August 20, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Can plasma levels of N-terminal pro-brain natriuretic peptide be useful in predicting the risk of developing chronic pulmonary hypertension in patients with pulmonary embolism?
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0292-xAuthors
Federico Lussana, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda Ospedaliera San Paolo Via A. di Rudinì, 8 20142 Milan ItalyGian Marco Podda, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda Ospedaliera San Paolo Via A. di Rudinì, 8 20142 Milan ItalyMarco Cattaneo, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda O...
Source: Internal and Emergency Medicine - August 4, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Acetazolamide-induced adynamic ileus
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0291-yAuthors
Massimo Gallerani, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 44100 Ferrara ItalyMaura Coletti, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 44100 Ferrara ItalyMauro Ferri, University of Ferrara Department of Ophthalmology Ferrara ItalyNicoletta Napolitano, University of Ferrara Department of Ophthalmology Ferrara ItalyBenedetta Boari, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 4410...
Source: Internal and Emergency Medicine - August 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Leukocyte interferon-α and ribavirin for treatment of chronic hepatitis C patients intolerant to pegylated-interferon
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Abstract Treatments for chronic hepatitis C (CHC) patients intolerant to pegylated interferons (peg-IFNs) are lacking. Thus, such patients
remain at high risk of developing an advanced and decompensated liver disease. Leukocyte IFN-α (Le-IFN-α) seems to possess
a safer profile than other natural and recombinant α-interferons, but no information is available for peg-IFN intolerant patients.
Accordingly, we evaluated the safety and efficacy of Le-IFN-α in patients intolerant to peg-IFNs. Twenty-five consecutive
CHC patients intolerant to peg-IFNs were prospectively enrolled. HCV genotype 1 was present in 8...
Source: Internal and Emergency Medicine - July 31, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Procalcitonin and acute coronary syndromes: a new biomarker for an old disease
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Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0295-7Authors
Luigi M. Biasucci, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome ItalyGina Biasillo, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome ItalyAntonella Stefanelli, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Giant left atrium in a woman with mitral prosthetic valve malfunction and history of rheumatic heart disease
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Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0280-1Authors
Gaspare Parrinello, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Cliniche 2 90127 Palermo ItalyDaniele Torres, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Cliniche 2 90127 Palermo ItalySalvatore Paterna, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Clinich...
Source: Internal and Emergency Medicine - July 27, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Essential thrombocythemia: past and present
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Abstract Essential thrombocythemia (ET) is a clonal myeloproliferative disorder characterized by sustained increase in platelet number
and tendency for thromboembolism. A somatic point mutation that causes a constitutive activation of the JAK2 gene is found
in one in two ET patients. ET is more common in women, its incidence being 0.6–2.5/100,000 patient/year and the median age
at diagnosis is 65–70 years. ET can affect all age groups, including children (0.09 cases/year), and is often diagnosed in
the third–fourth decade of life. Rare cases of familial ET have been reported. Miscarriages are 3–...
Source: Internal and Emergency Medicine - July 27, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
A thrombotic snake in the thoracic aorta
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Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0288-6Authors
Girolamo Catapano Minotti, Fondazione San Raffaele, Cittadella della Carità Taranto ItalyAndrea Corsonello, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Viale della Resistenza Pal. Alfa Scala H, Rende 87036 Cosenza ItalyGiovanni Guadalupi, Fondazione San Raffaele, Cittadella della Carità Taranto ItalyRaffaele Antonelli Incalzi, Fondazione San Raffaele, Cittadella della Carità Taranto Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 25, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Paradoxical embolism and thrombus trapped in patent foramen ovale in an old woman: a case report
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Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0289-5Authors
Vincenzo Brianti, Fidenza Hospital Emergency Medicine Fidenza ItalyCorrado Pattacini, Fidenza Hospital 2nd Unit of Internal Medicine Fidenza ItalyGianni Rastelli, Fidenza Hospital Emergency Medicine Fidenza ItalyMario Pini, Fidenza Hospital 2nd Unit of Internal Medicine Fidenza Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Tibial intercondylar eminence fractures in adults
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Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0286-8Authors
Cemil Kavalci, Trakya University Emergency Department, Faculty of Medicine 22030 Edirne TurkeyNezih Dagdeviren, Trakya University Department of Family Medicine, Faculty of Medicine Edirne TurkeyPolat Durukan, Erciyes University Department of Emergency Medicine, Faculty of Medicine Kayseri TurkeyYunsur Çevik, Ataturk Training and Research Hospital Emergency Department Ankara Turkey
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Brain natriuretic peptide and preclinical chronic thromboembolic pulmonary hypertension
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0287-7Authors
Marco Paolo Donadini, University of Insubria Department of Clinical Medicine Varese ItalyFrancesco Dentali, University of Insubria Department of Clinical Medicine Varese ItalyWalter Ageno, University of Insubria Department of Clinical Medicine Varese Italy
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Lyme carditis
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Content Type Journal ArticleCategory EM - Morbidity and Mortality ReportDOI 10.1007/s11739-009-0285-9Authors
Russell Evan Berger, Beth Israel Deaconess Medical Center Department of Emergency Medicine 1 Deaconess Road Boston MA 02215 USADaniel C. McGillicuddy, Beth Israel Deaconess Medical Center Department of Emergency Medicine 1 Deaconess Road Boston MA 02215 USA
Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Matrix metalloproteinases and peripheral arterial disease
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Abstract Matrix metalloproteinases (MMPs), a family of enzymes that degrade extracellular matrix, are emerging as important modulators
of atherothrombosis. MMPs are produced by inflammatory cells; some of them are also released by activated platelets and play
a crucial role in the remodeling processes, leading to atherosclerotic plaque formation, plaque rupture, arterial aneurysm
development, and critical limb ischemia. Independent from their matrix degrading activity, MMPs also regulate some cell functions
relevant to atherothrombosis, such as platelet activation, neutrophil activation, and vascular reactiv...
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Cholestasis preceding ileal perforation in a patient with typhoid fever
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Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0282-zAuthors
Seyfettin Köklü, Karargahtepe Mahallesi, Kumrulu Sokak, 18/2, Keçiören Ankara TurkeySelcan Gültuna, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyÖmer Başar, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyIlhami Yuksel, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyMurat Oktay, Dışkapı Yıldırım Beyazit Educational and Resear...
Source: Internal and Emergency Medicine - July 18, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Oral anticoagulant therapy in hemodialysis patients: do the benefits outweigh the risks?
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Abstract Managing oral anticoagulation may be difficult in hemodialysis patients because the antithrombotic effect can be counterbalanced
by an increased risk of hemorrhagic complications. There is insufficient evidence to recommend the routine use of warfarin
for thrombosis prophylaxis of the vascular access in all patients. If a decision for anticoagulation is made, dosing warfarin
to a “therapeutic” level is suggested, although the most appropriate target INR range remains unclear. Many hemodialysis patients
with atrial fibrillation have multiple risk factors for stroke and generally benefit from warf...
Source: Internal and Emergency Medicine - July 18, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
Procalcitonin in patients with acute coronary syndromes and cardiogenic shock submitted to percutaneous coronary intervention
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Abstract Procalcitonin (PCT) is known to be a biological diagnostic marker for severe sepsis, or septic shock in critically ill patients.
There are still contrasting data about a role of procalcitonin in patients with acute myocardial infarction or cardiogenic
shock, and in those with acute coronary syndromes, that is, non-ST-elevation myocardial infarction or unstable angina. We
evaluated plasma levels of procalcitonin and C-reactive protein (CRP) in 52 patients admitted to our intensive cardiac care
unit (ICCU): 14 patients with cardiogenic shock (CS) following ST-elevation myocardial infarction (STEMI), 1...
Source: Internal and Emergency Medicine - July 9, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals
