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Referees 2009email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Acknowledgement to RefereesDOI 10.1007/s11739-009-0328-2 Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 Journal Volume Volume 4 Journal Issue Volume 4, Number 6 / December, 2009 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - November 18, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Characteristics of patients in a ward of Academic Internal Medicine: implications for medical care, training programmes and researchemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  To describe the characteristics of “delayed discharge patients” and the factors associated with “delayed discharges”, we performed a 12-month observational study on patients classified as “delayed discharge patients” admitted to an Academic Internal Medicine ward. We assessed the demographic variables, the number and severity of diseases using the Geriatric Index of Comorbidity (GIC), the cognitive, affective and functional status using, respectively, the Mini Mental Stare Examination, the Geriatric Depression Scale and the Barthel Index. We assessed the total length of stay (T-LHS), the...
Source: Internal and Emergency Medicine - November 6, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

An unusual cause of small bowel obstructionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0326-4Authors Sidhartha Sinha, North Middlesex University Hospital NHS Trust London UKKezia Gaitskell, North Middlesex University Hospital NHS Trust London UKRudy Borgstein, North Middlesex University Hospital NHS Trust London UKRomi Navaratnam, North Middlesex University Hospital NHS Trust London UK Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - November 5, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Extended prophylaxis of venous thromboembolism with fondaparinux in patients undergoing major orthopaedic surgery in Italy: a cost-effectiveness analysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, our model shows that, when administered for extended prophylaxis of VTE following MOS, fondaparinux is more effective and cost saving than enoxaparin. Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-009-0324-6Authors Stefano Capri, Cattaneo-LIUC University Institute of Economics Castellanza ItalyWalter Ageno, University of Insubria Department of Clinical Medicine Varese ItalyDavide Imberti, Hospital of Piacenza Emergency Department, Thrombosis Center Piacenza ItalyGualtiero Palareti, University Hospital Department of Angiology and Blood Coagulation “Marino Golinelli” Bologna It...
Source: Internal and Emergency Medicine - November 5, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Measuring the impact of evidence: the Cochrane systematic review of organised stroke careemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0323-7Authors Rita Banzi, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyLorenzo Moja, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyAlessandro Liberati, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyGian Franco Gensini, University of Florence Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiologico e dei Vasi, Azie...
Source: Internal and Emergency Medicine - November 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Upper extremities deep venous thrombosis CVC-related: try to findemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0317-5Authors Rino Frizzelli, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyOrnella Tortelli, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyVincenzo Di Comite, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyRedenta Ghirardi, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyClaudio Pinzi, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile ...
Source: Internal and Emergency Medicine - October 31, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

New oral anticoagulants: just a new therapeutic option or a real breakthrough?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0327-3Authors Giancarlo Agnelli, Università di Perugia Medicina Interna e Cardiovascolare-Stroke Unit, Dipartimento di Medicina Interna Via G. Dottori 1 06129 Perugia ItalyCecilia Becattini, Università di Perugia Medicina Interna e Cardiovascolare-Stroke Unit, Dipartimento di Medicina Interna Via G. Dottori 1 06129 Perugia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - October 30, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Insights into the pathogenesis and management of thrombosis in polycythemia vera and essential thrombocythemiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The classic myeloproliferative neoplasms (MPNs) include polycythemia vera and essential thrombocythemia; their molecular basis has been described only recently with the demonstration of recurrent mutations in JAK2 or MPL. While life expectancy may not be significantly shortened, arterial and venous thrombosis constitute the major causes of morbidity and mortality, together with disease evolution to myelofibrosis or transformation to acute leukemia. Therapy is currently aimed at reducing the rate of thrombosis without increasing the risk of hematologic transformation by inappropriate exposure to cyto...
Source: Internal and Emergency Medicine - September 30, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

A 41-year-old woman with paroxysmal abdominal pain, weight loss and an epigastric bruitemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0318-4Authors Antonella Marcoccia, UOD ANGIOLOGIA, Ospedale Sandro Pertini, Via Dei Monti Tiburtini 00157 Rome ItalyMarco Di Tola, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyFrancesca Paris, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyGiuseppe Donato, Università Sapienza di Roma Dipartimento Medicina Clinica, Policlinico U. I Rome ItalyValerio Libanori, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyAntonio Pi...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

New evidence in infective and cardiovascular medicineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0315-7Authors Beatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Viale Morgagni 85 50134 Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Florence ItalyAndrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universitaria Careggi General Med...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Acquired haemophilia A: a case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0307-7Authors Daniela Colomba, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone” Piazza delle Cliniche no 2 90127 Palermo ItalyDomenico Di Raimondo, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone” Piazza delle Cliniche no 2 90127 Palermo ItalyLuciana Marino, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Spigelian hernia mimicking appendicular massemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0322-8Authors Sidhartha Sinha, North Middlesex University Hospital NHS Trust London UKArunthathi Pushparajasekaran, North Middlesex University Hospital NHS Trust London UKRudy Borgstein, North Middlesex University Hospital NHS Trust London UKDavid L. Stoker, North Middlesex University Hospital NHS Trust London UK Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Presence of low titre of antiphospholipid antibodies in cancer patients: a prospective studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, a high prevalence of low-titre aPL was found in cancer patients at diagnosis, but no statistical difference in thrombosis-free survival or in overall survival was observed between aPL positive and aPL negative patients. Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-009-0316-6Authors Mario Bazzan, CMID, Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Giovanni Bosco Hospital P.zza Donatori di Sangue 3 10154 Turin ItalyBarbara Montaruli, Laboratory Analysis and Oncology ...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Upper extremity deep vein thrombosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Upper extremities deep venous thrombosis (UEDVT) is a rare condition. According to the literature, approximately 4–10% of all cases of venous thrombosis may involve the subclavian, axillary or brachial veins. In the last few decades, the incidence of UEDVT has increased because of more frequent use of central venous catheters (CVCs) and cardiac pacemaker implantation. In addition, another common risk factor for UEDVT is cancer. UEDVT is classified as primary, approximately one-third of cases, which refers either to effort thrombosis or idiopathic UEDVT, or secondary, due to the presence of overt p...
Source: Internal and Emergency Medicine - September 29, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Matrix metalloproteinases and peripheral arterial diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory ErratumDOI 10.1007/s11739-009-0308-6Authors Chiara Busti, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyEmanuela Falcinelli, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyStefania Momi, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyPaolo Gresele, University of Perugia Division of Internal and Cardiovascula...
Source: Internal and Emergency Medicine - September 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Pulmonary arterial hypertensionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0321-9Authors Massimo Miniati, Università degli Studi di Firenze Dipartimento di Area Critica Medico Chirurgica Viale Morgagni 85 50134 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Emergency department use by the uninsured after health care reform in Massachusettsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study is limited by its analysis of a single large institution and a limited set of diagnoses. Content Type Journal ArticleCategory EM - OriginalDOI 10.1007/s11739-009-0313-9Authors Peter Smulowitz, Beth Israel Deaconess Medical Center Department of Emergency Medicine, WCC2 Boston MA 02215 USABruce E. Landon, Harvard Medical School Department of Medicine and Health Care Policy Boston MA USALaura Burke, Beth Israel Deaconess Medical Center Department of Emergency Medicine, WCC2 Boston MA 02215 USAChristopher Baugh, Brigham and Women’s Hospital and Massachusetts General Hospital Department of Emergency Medicine B...
Source: Internal and Emergency Medicine - September 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Hepcidin mutation in a β-thalassemia major patient with persistent severe iron overload despite chelation therapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0306-8Authors Lorena Duca, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyPaola Delbini, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyIsabella Nava, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyMaria Domenica Cappellini, University of Milan Department of Internal Medicine, Maggiore...
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

When pre-test probability can be deceptiveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0305-9Authors Micaela La Regina, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia ItalyMaria Cristina Pierantoni, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia ItalyMassimo Ratti, La Spezia I ItalyFrancesco Orlandini, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Heart failure and clinical practiceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0310-zAuthors Giorgio Costantino, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyAnna Maria Rusconi, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyStefano Guzzetti, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyNicola Montano, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan Italy Journal Internal and ...
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

A new approach to resident morning report: introducing “VAVUM”email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0311-yAuthors Mark D. Huffman, Northwestern University Division of Cardiology 676 North St. Clair St., Suite #600 Chicago IL 60611 USASamuel R. Kaufman, University of Michigan Health System Department of Internal Medicine Ann Arbor MI USASanjay Saint, University of Michigan Health System Department of Internal Medicine Ann Arbor MI USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Noncompaction of ventricular myocardium in an elderly womanemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0309-5Authors Alessio Currò, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyAlessandro Lauro, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyRaffaella Gallo, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyAndrea Corsonello, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

New direct thrombin inhibitorsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Direct thrombin inhibitors (DTIs) are a class of anticoagulants that bind selectively to thrombin and block its interaction with its substrates. Dabigatran etexilate and AZD0837, the new generation of DTIs, are now under intense development, and are potentially of great interest for internists. Dabigatran etexilate is a potent, non-peptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of thrombin molecule. It has been already licensed in the European Union and in Canada for the prevention of VTE in patients undergoing hip- a...
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Atrial fibrillation in a pregnant woman with a normal heartemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0312-xAuthors Luca Cacciotti, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome ItalyGiovanni S. Camastra, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome ItalyGerardo Ansalone, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - September 15, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Soluble forms of RAGE in internal medicineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The receptor for advanced glycation end-products (RAGE) and its ligands are intimately involved in the pathobiology of a wide range of diseases that share common features, such as enhanced oxidative stress, immune/inflammatory responses, and altered cell functions. Soluble forms of RAGE (sRAGE), including the splice variant endogenous secretory (es)RAGE, have been found circulating in plasma and tissues. Experimental data suggest that these isoforms may neutralize the ligand-mediated damage by acting as a decoy. Moreover, evidence is mounting to support a role for both sRAGE and esRAGE as biomarkers...
Source: Internal and Emergency Medicine - September 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Efficacy of medical therapy in a case of idiopathic pulmonary fibrosis due to gastroesophageal reflux diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0301-0Authors Franca Dipaola, A.O. “Istituti Clinici di Perfezionamento” U.O. Medicina Interna Viale Matteotti, 83 20099 Sesto San Giovanni Milan ItalyAndrea Galli, Ospedale “Civile di Vimercate” Medicina Interna Vimercate Milan ItalyCarlo Selmi, IRCCS Istituto Clinico Humanitas, Rozzano, Università di Milano Dipartimento Medicina Interna Milan ItalyRaffaello Furlan, Ospedale “Bolognini”, Università di Milano Medicina Generale Seriate Bergamo Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print I...
Source: Internal and Emergency Medicine - September 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Thiamine deficiency as a single cause of life-threatening lactic acidosis in a patient with acute axonal polyneuropathyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0303-yAuthors Petronella Johanna Van den Berg, St. Elisabeth Hospital Department of Neurology Tilburg The NetherlandsPeter J. Bijlstra, St. Elisabeth Hospital Department of Intensive Care Hilvarenbeekseweg 60 5022 GC Tilburg The NetherlandsGeert J. F. Brekelmans, St. Elisabeth Hospital Department of Neurology Tilburg The Netherlands Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

A case of thrombolysis in acute pulmonary embolism with right atrial thrombus: comparing current and past guidelinesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0304-xAuthors Francesco Paneni, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyErika Pagannone, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyAngela Gurgo, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalySebastiano Sciarretta, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyCamillo Auto...
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Heterogeneity and meta-analyses: do study results truly differ?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0296-6Authors Gianni Virgili, University of Florence Department of Oto-Neuro-Ophthalmological Surgical Sciences, Eye Clinic V.le Morgagni 85 50134 Florence ItalyAndrea A. Conti, University of Florence Department of Critical Care Medicine and Surgery Florence ItalyLorenzo Moja, Mario Negri Institute for Pharmacological Research Italian Cochrane Centre Milan ItalyGian Franco Gensini, University of Florence and Azienda Ospedaliero-Universitaria Careggi Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiol...
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Abnormalities of hemostasis and bleeding in chronic liver disease: the paradigm is challengedemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Chronic liver disease is characterized by a global hemostatic defect including platelet–vessel wall interaction (primary hemostasis), coagulation and fibrinolysis that may cause abnormalities of the relevant laboratory tests. The causal relationship between abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with the timing and incidence of actual bleeding. In this article, we review recent evidence from the literature that disputes the above paradigm, and opens new venues for laboratory/clinical research and patient management in this f...
Source: Internal and Emergency Medicine - August 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

New evidence in neoplastic and cardiovascular medicineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0294-8Authors Andrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyBeatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universit...
Source: Internal and Emergency Medicine - August 26, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Future drugs for migraineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0299-3Authors Luigi Alberto Pini, University of Modena and Reggio Emilia Headache Centre via del Pozzo, 71 41100 Modena Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - August 25, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

The microcirculation as a diagnostic and therapeutic target in sepsisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The microcirculation is defined as the smallest vessels where gas and nutrient exchange with tissues takes place. One of its primary functions is to ensure adequate oxygen delivery to meet the oxygen demands of tissue cells. Previous data from clinical and experimental studies and the recent development of new imaging modalities, such as Orthogonal Polarization Spectral videomicroscopy and Sidestream Dark Field imaging, have helped to identify the crucial role that microcirculation plays in sepsis. If not corrected, microcirculatory dysfunction can lead to respiratory distress in tissue cells and su...
Source: Internal and Emergency Medicine - August 25, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Splenic infarction: a rare cause of acute abdominal pain presenting in an older patient with primary antiphospholipid antibodies syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0298-4Authors Marco Rossato, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgical and Medical Sciences Via Ospedale 105 35128 Padua ItalyMartina Paccagnella, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgical and Medical Sciences Via Ospedale 105 35128 Padua ItalyMarta Burei, University of Padova Nuclear Medicine Unit, Department of Diagnostic Medical Sciences Padua ItalyGiovanni Federspil, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department...
Source: Internal and Emergency Medicine - August 21, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Oral factor Xa inhibitors for thromboprophylaxis in major orthopedic surgery: a reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, is a major cause of morbidity and mortality in patients undergoing major orthopedic surgery. Routine thromboprophylaxis has been the standard of care over the last 20 years. Currently available options for the prevention of VTE in major orthopedic surgery include low molecular weight heparins, vitamin K antagonists, and, more recently, the synthetic pentasaccharide fondaparinux. Although effective, all these drugs have several limitations and new oral antithrombotics offering predictable, effective and safe ant...
Source: Internal and Emergency Medicine - August 20, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Can plasma levels of N-terminal pro-brain natriuretic peptide be useful in predicting the risk of developing chronic pulmonary hypertension in patients with pulmonary embolism?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0292-xAuthors Federico Lussana, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda Ospedaliera San Paolo Via A. di Rudinì, 8 20142 Milan ItalyGian Marco Podda, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda Ospedaliera San Paolo Via A. di Rudinì, 8 20142 Milan ItalyMarco Cattaneo, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda O...
Source: Internal and Emergency Medicine - August 4, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Acetazolamide-induced adynamic ileusemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0291-yAuthors Massimo Gallerani, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 44100 Ferrara ItalyMaura Coletti, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 44100 Ferrara ItalyMauro Ferri, University of Ferrara Department of Ophthalmology Ferrara ItalyNicoletta Napolitano, University of Ferrara Department of Ophthalmology Ferrara ItalyBenedetta Boari, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 4410...
Source: Internal and Emergency Medicine - August 3, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Leukocyte interferon-α and ribavirin for treatment of chronic hepatitis C patients intolerant to pegylated-interferonemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Treatments for chronic hepatitis C (CHC) patients intolerant to pegylated interferons (peg-IFNs) are lacking. Thus, such patients remain at high risk of developing an advanced and decompensated liver disease. Leukocyte IFN-α (Le-IFN-α) seems to possess a safer profile than other natural and recombinant α-interferons, but no information is available for peg-IFN intolerant patients. Accordingly, we evaluated the safety and efficacy of Le-IFN-α in patients intolerant to peg-IFNs. Twenty-five consecutive CHC patients intolerant to peg-IFNs were prospectively enrolled. HCV genotype 1 was present in 8...
Source: Internal and Emergency Medicine - July 31, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Procalcitonin and acute coronary syndromes: a new biomarker for an old diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0295-7Authors Luigi M. Biasucci, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome ItalyGina Biasillo, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome ItalyAntonella Stefanelli, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 28, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Giant left atrium in a woman with mitral prosthetic valve malfunction and history of rheumatic heart diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0280-1Authors Gaspare Parrinello, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Cliniche 2 90127 Palermo ItalyDaniele Torres, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Cliniche 2 90127 Palermo ItalySalvatore Paterna, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Clinich...
Source: Internal and Emergency Medicine - July 27, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Essential thrombocythemia: past and presentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Essential thrombocythemia (ET) is a clonal myeloproliferative disorder characterized by sustained increase in platelet number and tendency for thromboembolism. A somatic point mutation that causes a constitutive activation of the JAK2 gene is found in one in two ET patients. ET is more common in women, its incidence being 0.6–2.5/100,000 patient/year and the median age at diagnosis is 65–70 years. ET can affect all age groups, including children (0.09 cases/year), and is often diagnosed in the third–fourth decade of life. Rare cases of familial ET have been reported. Miscarriages are 3–...
Source: Internal and Emergency Medicine - July 27, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

A thrombotic snake in the thoracic aortaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0288-6Authors Girolamo Catapano Minotti, Fondazione San Raffaele, Cittadella della Carità Taranto ItalyAndrea Corsonello, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Viale della Resistenza Pal. Alfa Scala H, Rende 87036 Cosenza ItalyGiovanni Guadalupi, Fondazione San Raffaele, Cittadella della Carità Taranto ItalyRaffaele Antonelli Incalzi, Fondazione San Raffaele, Cittadella della Carità Taranto Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 25, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Paradoxical embolism and thrombus trapped in patent foramen ovale in an old woman: a case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0289-5Authors Vincenzo Brianti, Fidenza Hospital Emergency Medicine Fidenza ItalyCorrado Pattacini, Fidenza Hospital 2nd Unit of Internal Medicine Fidenza ItalyGianni Rastelli, Fidenza Hospital Emergency Medicine Fidenza ItalyMario Pini, Fidenza Hospital 2nd Unit of Internal Medicine Fidenza Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Tibial intercondylar eminence fractures in adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0286-8Authors Cemil Kavalci, Trakya University Emergency Department, Faculty of Medicine 22030 Edirne TurkeyNezih Dagdeviren, Trakya University Department of Family Medicine, Faculty of Medicine Edirne TurkeyPolat Durukan, Erciyes University Department of Emergency Medicine, Faculty of Medicine Kayseri TurkeyYunsur Çevik, Ataturk Training and Research Hospital Emergency Department Ankara Turkey Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Brain natriuretic peptide and preclinical chronic thromboembolic pulmonary hypertensionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0287-7Authors Marco Paolo Donadini, University of Insubria Department of Clinical Medicine Varese ItalyFrancesco Dentali, University of Insubria Department of Clinical Medicine Varese ItalyWalter Ageno, University of Insubria Department of Clinical Medicine Varese Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Lyme carditisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory EM - Morbidity and Mortality ReportDOI 10.1007/s11739-009-0285-9Authors Russell Evan Berger, Beth Israel Deaconess Medical Center Department of Emergency Medicine 1 Deaconess Road Boston MA 02215 USADaniel C. McGillicuddy, Beth Israel Deaconess Medical Center Department of Emergency Medicine 1 Deaconess Road Boston MA 02215 USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Matrix metalloproteinases and peripheral arterial diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Matrix metalloproteinases (MMPs), a family of enzymes that degrade extracellular matrix, are emerging as important modulators of atherothrombosis. MMPs are produced by inflammatory cells; some of them are also released by activated platelets and play a crucial role in the remodeling processes, leading to atherosclerotic plaque formation, plaque rupture, arterial aneurysm development, and critical limb ischemia. Independent from their matrix degrading activity, MMPs also regulate some cell functions relevant to atherothrombosis, such as platelet activation, neutrophil activation, and vascular reactiv...
Source: Internal and Emergency Medicine - July 24, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Cholestasis preceding ileal perforation in a patient with typhoid feveremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0282-zAuthors Seyfettin Köklü, Karargahtepe Mahallesi, Kumrulu Sokak, 18/2, Keçiören Ankara TurkeySelcan Gültuna, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyÖmer Başar, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyIlhami Yuksel, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyMurat Oktay, Dışkapı Yıldırım Beyazit Educational and Resear...
Source: Internal and Emergency Medicine - July 18, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Oral anticoagulant therapy in hemodialysis patients: do the benefits outweigh the risks?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Managing oral anticoagulation may be difficult in hemodialysis patients because the antithrombotic effect can be counterbalanced by an increased risk of hemorrhagic complications. There is insufficient evidence to recommend the routine use of warfarin for thrombosis prophylaxis of the vascular access in all patients. If a decision for anticoagulation is made, dosing warfarin to a “therapeutic” level is suggested, although the most appropriate target INR range remains unclear. Many hemodialysis patients with atrial fibrillation have multiple risk factors for stroke and generally benefit from warf...
Source: Internal and Emergency Medicine - July 18, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals

Procalcitonin in patients with acute coronary syndromes and cardiogenic shock submitted to percutaneous coronary interventionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Procalcitonin (PCT) is known to be a biological diagnostic marker for severe sepsis, or septic shock in critically ill patients. There are still contrasting data about a role of procalcitonin in patients with acute myocardial infarction or cardiogenic shock, and in those with acute coronary syndromes, that is, non-ST-elevation myocardial infarction or unstable angina. We evaluated plasma levels of procalcitonin and C-reactive protein (CRP) in 52 patients admitted to our intensive cardiac care unit (ICCU): 14 patients with cardiogenic shock (CS) following ST-elevation myocardial infarction (STEMI), 1...
Source: Internal and Emergency Medicine - July 9, 2009 Category: Emergency Medicine Tags: Internal and Emergency Medicine Source Type: journals