Work Stress and the Risk of Cancer: a Meta ‐analysis of Observational Studies
This study aimed to investigate the association between work stress and the risk of cancer and in relation to major potential confounding and modifying factors. We systematically searched three electronic databases, hand ‐searched references and citations of retrieved articles, and consulted experts to identify studies on assessing the association between work stress and the risk of cancer. The relative risks (RRs) of cancer associated with work stress were estimated using a random‐effects model, and stratified by exposure measurement, study design, gender, study location, cancer site, smoking, drinking, body mass inde...
Source: International Journal of Cancer - November 28, 2018 Category: Cancer & Oncology Authors: Tingting Yang, Yan Qiao, Siyun Xiang, Wenzhen Li, Yong Gan, Yongchun Chen Tags: Research Article Source Type: research

The role of microbiota in the development of colorectal cancer
This article reviews the pathways of microbial signaling in the intestinal epithelial barrier, the role of microbiota in inflammatory colorectal tumors, and typical microbial carcinogenesis. Finally, by gaining a deeper understanding of the intestinal microbiota, we hope to achieve the goal of treating colorectal cancer using current microbiota technologies, such as fecal microbiological transplantation. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Zhujiang Dai, Jingqiu Zhang, Qi Wu, Juan Chen, Jun Liu, Lu Wang, Chaowu Chen, Jiaming Xu, Hongpeng Zhang, Chunfeng Shi, Zhen Li, Huiwen Fang, Chaobiao Lin, Dong Tang, Daorong Wang Tags: Mini Review Source Type: research

Issue Information
International Journal of Cancer, Volume 143, Issue 12, Page 3282-3283, 15 December 2018. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 26, 2018 Category: Cancer & Oncology Tags: Issue Information Source Type: research

Issue Information
International Journal of Cancer, Volume 143, Issue 12, Page 3043-3049, 15 December 2018. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 26, 2018 Category: Cancer & Oncology Tags: Issue Information Source Type: research

A functional ex vivo assay to detect PARP1 ‐EJ repair and radiosensitization by PARP‐inhibitor in prostate cancer
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 26, 2018 Category: Cancer & Oncology Authors: S. K öcher, B. Beyer, T. Lange, L. Nordquist, J. Volquardsen, S. Burdak‐Rothkamm, T. Schlomm, C. Petersen, K. Rothkamm, W.Y. Mansour Tags: Research Article Source Type: research

Large scale in ‐vivo micro‐RNA loss of function screen identified miR‐29a, miR‐100 and miR‐155 as modulators of radioresistance and tumor‐stroma communication
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Azadeh Fahim Golestaneh, Laura S.M. Lecker, Julian Schlegel, Ali Nowrouzi, Christian Schwager, Sarah Meister, Wilko Weichert, J ürgen Debus, Amir Abdollahi Tags: Research Article Source Type: research

Molecular mechanisms of resistance to CDK4/6 inhibitors in breast cancer: A review
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Kamal Pandey, Hee ‐Jung An, Seung Ki Kim, Seung Ah Lee, Sewha Kim, Sun Min Lim, Gun Min Kim, Joohyuk Sohn, Yong Wha Moon Tags: Mini Review Source Type: research

The GPRC5A frameshift variant c.183del is not associated with increased breast cancer risk in BRCA1 mutation carriers
International Journal of Cancer, Volume 0, Issue ja, -Not available-. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 26, 2018 Category: Cancer & Oncology Authors: Kristina Klaschik, Jan Hauke, Guido Neidhardt, Christian Tr änkle, Harald M. Surowy, Stefanie Heilmann‐Heimbach, Gunter Rappl, Elisabeth Mangold, Norbert Arnold, Dieter Niederacher, Christian Sutter, Barbara Burwinkel, Christoph Engel, Bar Tags: Letter to the Editor Source Type: research

Response to: The GPRC5A frameshift variant c.183del is not associated with increased breast cancer risk in BRCA1 mutation carriers
International Journal of Cancer, Volume 0, Issue ja, -Not available-. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 25, 2018 Category: Cancer & Oncology Authors: Daria R. Bulanova, Mikko Helenius, Anna P. Sokolenko, Sergey G. Kuznetsov, Evgeny N. Imyanitov Tags: Letter to the Editor Source Type: research

Increasing risk of uterine cervical cancer among young Japanese women: Comparison of incidence trends in Japan, South Korea and Japanese ‐Americans between 1985 and 2012
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 25, 2018 Category: Cancer & Oncology Authors: Mai Utada, Pavel Chernyavskiy, Won Jin Lee, Silvia Franceschi, Catherine Sauvaget, Amy Berrington de Gonzalez, Diana R. Withrow Tags: Research Article Source Type: research

Different characteristics and survival in non ‐small cell lung cancer patients with primary and acquired EGFR T790M mutation
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 25, 2018 Category: Cancer & Oncology Authors: Shuyuan Wang, Bo Yan, Yanwei Zhang, Jianlin Xu, Rong Qiao, Yu Dong, Bo Zhang, Yiming Zhao, Lele Zhang, Jie Qian, Jun Lu, Ruiying Zhao, Baohui Han Tags: Research Article Source Type: research

Strong associations of a healthy lifestyle with all stages of colorectal carcinogenesis: results from a large cohort of participants of screening colonoscopy
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 23, 2018 Category: Cancer & Oncology Authors: Vanessa Erben, Prudence R Carr, Bernd Holleczek, Christa Stegmaier, Michael Hoffmeister, Hermann Brenner Tags: Research Article Source Type: research

A controlled trial of HNSCC patient ‐derived xenografts reveals broad efficacy of PI3Kα inhibition in controlling tumor growth
Head and neck squamous cell carcinomas (HNSCCs) frequently harbor alterations in the PI3K/AKT/mTOR signalling axis, particularly in thePIK3CA gene. PI3K ‐targeted agents have therefore gained considerable preclinical and clinical interest as emerging therapies for HNSCC. Identification of predictive biomarkers of response would advance the clinical application of PI3K‐targeted drugs for patients in order to achieve maximal benefit. To date, stud ies of drug biomarkers have largely focused on screening cell lines, with much more limitedin vivo testing, usually only as validation. This approach has rarely enabled accurat...
Source: International Journal of Cancer - November 23, 2018 Category: Cancer & Oncology Authors: Kara M. Ruicci, Jalna Meens, Ren X. Sun, Giananthony Rizzo, Nicole Pinto, John Yoo, Kevin Fung, Danielle MacNeil, Joe S. Mymryk, John W. Barrett, Paul C. Boutros, Laurie Ailles, Anthony C. Nichols Tags: Short Report Source Type: research

Selective BTK inhibition improves bendamustine therapy response and normalizes immune effector functions in chronic lymphocytic leukemia
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 23, 2018 Category: Cancer & Oncology Authors: Eriong Lee ‐Vergés, Bola S. Hanna, Haniyeh Yazdanparast, Vanina Rodríguez, Marta Leonor Rodríguez, Ariadna Giró, Anna Vidal‐Crespo, Laia Rosich, Virginia Amador, Marta Aymerich, Neus Villamor, Julio Delgado, Peter Lichter, Patricia P Tags: Research Article Source Type: research

CLPTM1L/CRR9 Ectodomain Interaction with GRP78 at the Cell Surface Signals for Survival and Chemoresistance upon ER Stress in Pancreatic Adenocarcinoma Cells
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 23, 2018 Category: Cancer & Oncology Authors: William R. Clarke, Laufey Amundadottir, Michael A. James Tags: Research Article Source Type: research