Unique immunohistochemical profiles of MUC5AC, MUC6, P53, and Ki67 in gastric atypical hyperplasia and dysplasia
CONCLUSIONS: The integration of histomorphological features and expression profiles of MUC5AC, MUC6, P53, and Ki67 is instrumental in diagnosing gastric atypical hyperplasia and dysplasia.PMID:38577693 | PMC:PMC10988094 | DOI:10.62347/JVIX8887 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Lanfang Miao Yuanyuan Sun Mei Guo Haijun Yang Xianjuan Du Junkuo Li Jingwei Shen Xiaomin Wang Ruixue Lei Source Type: research

Post-therapeutic squamous cell transformation of a metastatic prostate adenocarcinoma with comparison of molecular profiles: a case report and review of the literature
Int J Clin Exp Pathol. 2024 Mar 15;17(3):78-82. doi: 10.62347/ZQCI9925. eCollection 2024.ABSTRACTTransformation of primary prostate adenocarcinoma to squamous cell carcinoma after initial treatment with chemotherapy and hormonal therapy is extremely rare and typically results in rapid treatment-refractory disease progression and death. Here, we present a case of a 64-year-old man who was initially diagnosed with metastatic prostate adenocarcinoma (positive PSA and NKX3.1 stains, total PSA 747.2 ng/ml) to the thoracic spine (T8) in 2019. The patient received androgen deprivation therapy and chemotherapy with good response (...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Peizi Li George K Haines Qiusheng Si Brett Baskovich Source Type: research

Multifocal lower limb hemangioendothelioma in a young female: a case report and review of the literature
Int J Clin Exp Pathol. 2024 Mar 15;17(3):83-89. doi: 10.62347/YRCF9861. eCollection 2024.ABSTRACTA 26-year-old female presented with pain and swelling of distal thigh and distal leg. She was diagnosed with multifocal epitheloid hemangioendothelioma (EHE) and was successfully treated with wide resection of femoral and tibial lesions followed by their reconstruction using vascularised fibular graft and local bone grafting. One year into follow-up, the patient remained asymptomatic with full Range Of Motion (ROM) and full weight bearing walking. This case illustrates a unique multifocal presentation of hemangioendothelioma an...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Sandeep Kumar Yadav Ashraf Jamal Prabodh Kantiwal Abhay Elhence Poonam Elhence Balamurugan Thirunavukkarasu Suvinay Saxena Source Type: research

Spondylodiscitis after sacral colpopexy: diagnose early to treat earlier
Int J Clin Exp Pathol. 2024 Mar 15;17(3):90-95. doi: 10.62347/RERC7901. eCollection 2024.ABSTRACTSpondylodiscitis following sacral colpopexy for Pelvic Organ Prolapse (POP) represents a rare complication with severe consequences. Authors performed a literature search, from 2000 to 2022, to set a narrative review of literature. Spondylodiscitis is an uncommon but dangerous side effect of a routine surgical treatment that needs to be identified and treated right away to prevent worsening clinical consequences. Suboptimal dissection of the sacral promontory and/or site infection are associated with spondylodiscitis. When spon...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Andrea Tinelli Murat Yassa Giuseppe Marzo Daniela Romualdi Matteo Frigerio Alessio Melcarne Giovanni Scambia Giovanni Pecorella Andrea Morciano Source Type: research

Prognostic impact of tumor-associated neutrophils in breast cancer
CONCLUSION: The present results suggest that a higher density of TANs correlates with unfavorable prognostic factors in breast cancer. Further research on clinicopathological and genetic factors associated with TANs in breast cancer is needed.PMID:38577697 | PMC:PMC10988089 | DOI:10.62347/JQDQ1527 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Akinari Kakumoto Tsengelmaa Jamiyan Hajime Kuroda Oi Harada Tomomi Yamaguchi-Isochi Shogo Baba Yasutaka Kato Hiroshi Nishihara Hiroyuki Kawami Source Type: research

Intracardiac leakage of cement during artificial femoral head replacement: a case report and review
Int J Clin Exp Pathol. 2024 Mar 15;17(3):72-77. doi: 10.62347/FHAR9264. eCollection 2024.ABSTRACTBone cement leakage from the femoral medullary cavity is a rare complication following hip replacement. Currently, there are no reports of bone cement leakage into the heart. Here, we report an 81-year-old female patient with right femoral neck fracture. A thorough preoperative examination showed that bone cement had leaked into the heart during right femoral head replacement, leading to the death of the patient that night. Postoperative cardiac ultrasound showed that bone cement entered the vascular system through the femoral ...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Jin Li Yanqing Zhang Hongmei Zhang Shanyun Jiang Xindong Wu Source Type: research

Unique immunohistochemical profiles of MUC5AC, MUC6, P53, and Ki67 in gastric atypical hyperplasia and dysplasia
CONCLUSIONS: The integration of histomorphological features and expression profiles of MUC5AC, MUC6, P53, and Ki67 is instrumental in diagnosing gastric atypical hyperplasia and dysplasia.PMID:38577693 | PMC:PMC10988094 | DOI:10.62347/JVIX8887 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Lanfang Miao Yuanyuan Sun Mei Guo Haijun Yang Xianjuan Du Junkuo Li Jingwei Shen Xiaomin Wang Ruixue Lei Source Type: research

Post-therapeutic squamous cell transformation of a metastatic prostate adenocarcinoma with comparison of molecular profiles: a case report and review of the literature
Int J Clin Exp Pathol. 2024 Mar 15;17(3):78-82. doi: 10.62347/ZQCI9925. eCollection 2024.ABSTRACTTransformation of primary prostate adenocarcinoma to squamous cell carcinoma after initial treatment with chemotherapy and hormonal therapy is extremely rare and typically results in rapid treatment-refractory disease progression and death. Here, we present a case of a 64-year-old man who was initially diagnosed with metastatic prostate adenocarcinoma (positive PSA and NKX3.1 stains, total PSA 747.2 ng/ml) to the thoracic spine (T8) in 2019. The patient received androgen deprivation therapy and chemotherapy with good response (...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Peizi Li George K Haines Qiusheng Si Brett Baskovich Source Type: research

Multifocal lower limb hemangioendothelioma in a young female: a case report and review of the literature
Int J Clin Exp Pathol. 2024 Mar 15;17(3):83-89. doi: 10.62347/YRCF9861. eCollection 2024.ABSTRACTA 26-year-old female presented with pain and swelling of distal thigh and distal leg. She was diagnosed with multifocal epitheloid hemangioendothelioma (EHE) and was successfully treated with wide resection of femoral and tibial lesions followed by their reconstruction using vascularised fibular graft and local bone grafting. One year into follow-up, the patient remained asymptomatic with full Range Of Motion (ROM) and full weight bearing walking. This case illustrates a unique multifocal presentation of hemangioendothelioma an...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Sandeep Kumar Yadav Ashraf Jamal Prabodh Kantiwal Abhay Elhence Poonam Elhence Balamurugan Thirunavukkarasu Suvinay Saxena Source Type: research

Spondylodiscitis after sacral colpopexy: diagnose early to treat earlier
Int J Clin Exp Pathol. 2024 Mar 15;17(3):90-95. doi: 10.62347/RERC7901. eCollection 2024.ABSTRACTSpondylodiscitis following sacral colpopexy for Pelvic Organ Prolapse (POP) represents a rare complication with severe consequences. Authors performed a literature search, from 2000 to 2022, to set a narrative review of literature. Spondylodiscitis is an uncommon but dangerous side effect of a routine surgical treatment that needs to be identified and treated right away to prevent worsening clinical consequences. Suboptimal dissection of the sacral promontory and/or site infection are associated with spondylodiscitis. When spon...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Andrea Tinelli Murat Yassa Giuseppe Marzo Daniela Romualdi Matteo Frigerio Alessio Melcarne Giovanni Scambia Giovanni Pecorella Andrea Morciano Source Type: research

Prognostic impact of tumor-associated neutrophils in breast cancer
CONCLUSION: The present results suggest that a higher density of TANs correlates with unfavorable prognostic factors in breast cancer. Further research on clinicopathological and genetic factors associated with TANs in breast cancer is needed.PMID:38577697 | PMC:PMC10988089 | DOI:10.62347/JQDQ1527 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Akinari Kakumoto Tsengelmaa Jamiyan Hajime Kuroda Oi Harada Tomomi Yamaguchi-Isochi Shogo Baba Yasutaka Kato Hiroshi Nishihara Hiroyuki Kawami Source Type: research

Intracardiac leakage of cement during artificial femoral head replacement: a case report and review
Int J Clin Exp Pathol. 2024 Mar 15;17(3):72-77. doi: 10.62347/FHAR9264. eCollection 2024.ABSTRACTBone cement leakage from the femoral medullary cavity is a rare complication following hip replacement. Currently, there are no reports of bone cement leakage into the heart. Here, we report an 81-year-old female patient with right femoral neck fracture. A thorough preoperative examination showed that bone cement had leaked into the heart during right femoral head replacement, leading to the death of the patient that night. Postoperative cardiac ultrasound showed that bone cement entered the vascular system through the femoral ...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Jin Li Yanqing Zhang Hongmei Zhang Shanyun Jiang Xindong Wu Source Type: research

Unique immunohistochemical profiles of MUC5AC, MUC6, P53, and Ki67 in gastric atypical hyperplasia and dysplasia
CONCLUSIONS: The integration of histomorphological features and expression profiles of MUC5AC, MUC6, P53, and Ki67 is instrumental in diagnosing gastric atypical hyperplasia and dysplasia.PMID:38577693 | PMC:PMC10988094 | DOI:10.62347/JVIX8887 (Source: International Journal of Clinical and Experimental Pathology)
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Lanfang Miao Yuanyuan Sun Mei Guo Haijun Yang Xianjuan Du Junkuo Li Jingwei Shen Xiaomin Wang Ruixue Lei Source Type: research

Post-therapeutic squamous cell transformation of a metastatic prostate adenocarcinoma with comparison of molecular profiles: a case report and review of the literature
Int J Clin Exp Pathol. 2024 Mar 15;17(3):78-82. doi: 10.62347/ZQCI9925. eCollection 2024.ABSTRACTTransformation of primary prostate adenocarcinoma to squamous cell carcinoma after initial treatment with chemotherapy and hormonal therapy is extremely rare and typically results in rapid treatment-refractory disease progression and death. Here, we present a case of a 64-year-old man who was initially diagnosed with metastatic prostate adenocarcinoma (positive PSA and NKX3.1 stains, total PSA 747.2 ng/ml) to the thoracic spine (T8) in 2019. The patient received androgen deprivation therapy and chemotherapy with good response (...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Peizi Li George K Haines Qiusheng Si Brett Baskovich Source Type: research

Multifocal lower limb hemangioendothelioma in a young female: a case report and review of the literature
Int J Clin Exp Pathol. 2024 Mar 15;17(3):83-89. doi: 10.62347/YRCF9861. eCollection 2024.ABSTRACTA 26-year-old female presented with pain and swelling of distal thigh and distal leg. She was diagnosed with multifocal epitheloid hemangioendothelioma (EHE) and was successfully treated with wide resection of femoral and tibial lesions followed by their reconstruction using vascularised fibular graft and local bone grafting. One year into follow-up, the patient remained asymptomatic with full Range Of Motion (ROM) and full weight bearing walking. This case illustrates a unique multifocal presentation of hemangioendothelioma an...
Source: International Journal of Clinical and Experimental Pathology - April 5, 2024 Category: Pathology Authors: Sandeep Kumar Yadav Ashraf Jamal Prabodh Kantiwal Abhay Elhence Poonam Elhence Balamurugan Thirunavukkarasu Suvinay Saxena Source Type: research