International Journal of Developmental Neuroscience This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Grey matter alterations in generalized anxiety disorder: A voxel-wise meta-analysis of voxel-based morphometry studies
CONCLUSION: GAD might have the modest grey matter alterations in the left superior temporal gyrus. Anxiety severity might be related to the grey matter alterations in the limbic regions, such as the right insula, lenticular nucleus, putamen and striatum. This kind of correlation might be related to the effects of adult GAD. Future studies with adequate sample sizes and sophisticated GAD categories will be needed.PMID:38638086 | DOI:10.1002/jdn.10330 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - April 19, 2024 Category: Neuroscience Authors: Chang-Hsien Ou Chiu-Shih Cheng Pei-Ling Lin Cheng-Lung Lee Source Type: research

Compartmental neuronal degeneration in the ventral striatum induced by status epilepticus in young rats' brain in comparison with adults
Int J Dev Neurosci. 2024 Apr 17. doi: 10.1002/jdn.10331. Online ahead of print.ABSTRACTAccording to experimental and clinical studies, status epilepticus (SE) causes neurodegenerative morphological changes not only in the hippocampus and other limbic structures, it also affects the thalamus and the neocortex. In addition, several studies reported atrophy, metabolic changes, and neuronal degeneration in the dorsal striatum. The literature lacks studies investigating potential neuronal damage in the ventral component of the striatopallidal complex (ventral striatum [VS] and ventral pallidum) in SE experimentations. To better...
Source: International Journal of Developmental Neuroscience - April 17, 2024 Category: Neuroscience Authors: Azzat Al-Redouan Martin Salaj Hana Kubova Rastislav Druga Source Type: research

Experience of treatment in critical Guillain-Barre Syndrome case after COVID-19 vaccination
CONCLUSIONS: For patients with previous radiculitis, COVID-19 vaccination may increase the susceptibility to GBS. Thus, it is recommended to extend the vaccination interval for these patients and ensure that any potential increased risk is continually assessed.PMID:38590219 | DOI:10.1002/jdn.10325 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - April 9, 2024 Category: Neuroscience Authors: Chunying Zhu Huan Wang Yingfu Zhang Wentao Wang Jia Wang Wei Li Source Type: research

Gut-brain barrier dysfunction bridge autistic-like behavior in mouse model of maternal separation stress: A behavioral, histopathological, and molecular study
Int J Dev Neurosci. 2024 Apr 7. doi: 10.1002/jdn.10329. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is a fast-growing neurodevelopmental disorder throughout the world. Experiencing early life stresses (ELS) like maternal separation (MS) is associated with autistic-like behaviors. It has been proposed that disturbance in the gut-brain axis-mediated psychiatric disorders following MS. The role of disruption in the integrity of gut-brain barrier in ASD remains unclear. Addressing this knowledge gap, in this study we aimed to investigate role of the gut-brain barrier integrity in mediating autistic-like behavi...
Source: International Journal of Developmental Neuroscience - April 7, 2024 Category: Neuroscience Authors: Negin Rowshan Maryam Anjomshoa Anahita Farahzad Elham Bijad Hossein Amini-Khoei Source Type: research

Compound heterozygous mutations in three Chinese patients of Segawa syndrome and their treatment outcomes
Int J Dev Neurosci. 2024 Apr 2. doi: 10.1002/jdn.10328. Online ahead of print.ABSTRACTSegawa syndrome is a rare autosomal recessive form of dopa-responsive dystonia resulting from TH gene dysfunction. Patients typically exhibit symptoms such as generalized dystonia, rigidity, tremors, infantile Parkinsonism, and pseudo-spastic paraplegia. Levodopa is often an effective treatment. Due to its rarity, high heterogeneity, and poorly understood pathological mutation and phenotype spectrums, as well as genotype-phenotype and genotype-treatment outcome correlations, Segawa syndrome poses diagnostic and therapeutic challenges. In ...
Source: International Journal of Developmental Neuroscience - April 3, 2024 Category: Neuroscience Authors: Jie Zhang Yaxin Huang Yulei Hu Bing Bai Source Type: research